HAART to HEART: A multidisicplinary adherence support and evaluation program in Ryan-White funded community health centers
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1 HAART to HEART: A multidisicplinary adherence support and evaluation program in Ryan-White funded community health centers Lisa R Hirschhorn, Susan Goldin, Theresa Meehan, Israel Flores, William Woods, Jeanne Day, Lindsay A Ruhlmann, Judith Steinberg, Laurie M Kunches Dimock Community Health Center, JSI Research and Training, Neponsett Health Center
2 Adherence at a CHC Dimock Community Health Center (DCHC) urban-based comprehensive CHC with Title IIIbfunded HIV primary and specialty care In : Dimock Community Health Center (DCHC), 58% of pts on PI did not achieve durable suppression Toxicity and side effects were significantly associated with failure (63% vs 30%) and poor adherence (61% vs 41%) 30% of HAART failures were unable to tolerate Rx for 12 weeks In a larger study, the most common patientreported reason for stopping HAART was side effects
3 HAART to HEART concept For highly ACTIVE antiretroviral therapy (HAART) to be EFFECTIVE, you must be able to access, accept, take, tolerate and adhere HAART to HEART, initiated to improve adherence and treatment success by changing highly active antiretroviral therapy into highly effective antiretroviral therapy
4 Changes in the clinic Interventions to improve the durability of PI and HAART response were strengthened to include aggressive side effect and toxicity management Efforts included the development of a more aggressive and comprehensive adherence program to improve treatment success (education, adherence, optimal regimen design etc.) Target population was ~200 HIV patients in primary care 85% communities of color, 45% women ~60% HCV (+), >75% history of substance abuse and/or mental illness
5 Program Design Multidisciplinary team integrated in to HIV primary care clinic Educate of all team members on treatment, side effects and management and adherence Traditional adherence aids Nutritional support Mental health counseling Peer support and advocacy Patient education
6 Adherence support team HIV specialist (team leader) PCP (if not the team leader) Nurse case manager/educator Peer educator/advocate Mental health counselor Nutritionist Psychosocial case manager(s) Psychiatrist Other (employment specialist, referral coordinator, interpreter)
7 Design (continued) Peers received specialized training in adherence and treatment, and supervision from mental health counselor Develop and collect educational materials (English and Spanish) from web and publications to create permanent resources and patient manuals Manual translated into 3 languages and updated regularly as collaboration between DCHC and JSI
8 Protocol for HAART Initiation All patients met with their PCP for initial HAART discussion. Decision and initiation takes 2-3 visits After PCP visit, the patient meets with a nurse case manager/educator who reinforces education and provide additional information All patients are offered a peer educator. If they accept the peer support, peers contact regularly Psychosocial case manager is involved in >70% of cases Education and support includes use of a manual, regimen and adherence review, general HIV education, aggressive referrals for mental health, substance abuse, nutrition, psychosocial needs
9 Results Over 75% of patients on HAART engaged in some aspect of the program 85% from communities of color 40% women High rates of comorbid conditions (HCV, mental illness, substance abuse) required most to access >1 service and needs changed over time Follow-up chart review in 1999 showed that >90% of individuals who achieved viral suppression remained suppressed for >1 year
10 SPNS and HAART to HEART Funded in October 1999 including expansion of adherence program to second CHC and evaluation of efficacy of homebased component This has allowed a more intensive look at the program Preliminary results from DCHC are presented
11 Preliminary SPNS data 43 patients on HAART enrolled into program and screened for problems with adherence 57% women, 87% communities of color 42% IDU risk, 61% substance abuse, 38% mental illness 63% had viral loads below level of detection 65% reported 100% 3 day adherence and 56% reported missing < 1 time/week Lower levels of HIV-related knowledge was associated with missing doses Both substance abuse and difficulty taking medications on time were associated with not achieving undetectable plasma viral load
12 Role of Peer Adherence Counselor 2 peers hired and trained by the clinic to provide education and adherence support In the first 7 months of SPNS evaluation, 46% of enrolled clients accepted a PAC (67% women, 67% minority) 2 PACS initiated 168 encounters (range 1-25/client) with 83% resulting in contact by phone or face-to-face
13 Role of Peer Continued Direct services included education and adherence, but also included referrals for mental health or substance abuse treatment, housing, utilities and advocacy for care and treatment Women had high rates of chaos, with intervention provided in mean of 2.8 areas in addition to adherence and education
14 Lessons Learned Establishment of a multidisciplinary adherence support program integrated into a CHC HIV primary and specialty care program can be done, but it takes time and effort Adherence needs change with time therefor, the program must also be flexible and responsive to needs It is hard to collect data Peers are an effective and valuable part of the team, but require training to include boundaries, triage and self-support
15 Future Directions Further funding through SPNS grant in collaboration with John Snow and new CHC to continue evaluation Continue training in clinic and through NEAETC to ensure state-of-the-art care and side effect management Continue to address new challenges: hepatitis C, aging, lipodystrophy, lactic acidosis, etc. Continue to monitor effectiveness as people survive longer and medications change
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