Wahlberg Elsner Kanerva Maibach Management of Positive Patch Test Reactions
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1 Wahlberg Elsner Kanerva Maibach Management of Positive Patch Test Reactions
2 Springer-Verlag Berlin Heidelberg GmbH
3 J.E. Wahlberg P. Elsner L. Kanerva H.I. Maibach (Eds.) Management of Positive Patch Test Reactions 123
4 ISBN Library of Congress Cataloging-in-Publication Data Management of positive patch test reactions / Jan E. Wahlberg [et al.]. p. cm. Includes bibliographical references. ISBN ISBN (ebook) DOI / Contact dermatitis Handbooks, manuals, etc. I. Wahlberg, Jan E. RL244.M dc This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer-Verlag. Violations are liable for prosecution under the German Copyright Law. Springer-Verlag Berlin Heidelberg 2003 Originally published by Springer-Verlag Berlin Heidelberg New York in 2003 Cover design: Erich Kirchner, Heidelberg Typesetting: Fotosatz-Service Köhler GmbH, Würzburg Printing and bookbinding: Stürtz AG, Würzburg The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publisher cannot guarantee the accuracy of any information about the application of operative techniques and medications contained in this book. In every individual case the user must check such information by consulting the relevant literature. Printed on acid-free paper 24/3150PF
5 Preface The International Contact Dermatitis Research Group (ICDRG) updated their standard series in Proposal for a revised international standard series of patch tests 1 ; 34 allergens/test preparations from three standard series from Europe (EECDRG), from USA (NACDG), and from Japan (JSDS) were compared. They were divided in a modified international standard series (20 allergens), and an extended international standard series and additional useful allergens (8+6, respectively). These 34 allergens/test preparations are reviewed in this booklet. To aid the reader, we provide an abbreviated exposure sheet which we hope will be of practical value. The editors welcome comments, additions, corrections, and suggestions for future editions. We would like to thank all our contributors for their excellent work. Jan E. Wahlberg, Peter Elsner, Lasse Kanerva, Howard I. Maibach, for the ICDRG 1 Contact Dermatitis (1997) 36:
6 Addresses Editors Wahlberg, Jan E. National Institute for Working Life Stockholm Elsner, Peter Universitätsklinikum Jena Erfurter Straße Jena Germany Kanerva, Lasse Institute of Occupational Health Section of Dermatology Topeliuksenkatu 41 a Helsinki Finland Maibach, Howard I. University of California San Francisco School of Medicine San Francisco, CA USA
7 VIII Addresses Contributors Alanko, Kristiina Finnish Institute of Occupational Health Topeliuksenkatu 41 aa Helsinki Finland Andersen, Klaus E. Odense University Hospital 5000 Odense C Denmark Avnstorp, Christian Klinik for Hudsygdomme Roskildevej Rödovre Denmark Bruynzeel, Derk P. Free University Hospital De Boelelaan HV Amsterdam The Netherlands Bruze, Magnus Department of Occupational and Environmental Dermatology Malmö University Hospital Malmö Chowdhury, Mahbub M. U. University Hospital of Wales Box 100, Heath Park Cardiff CF14 4XW United Kingdom
8 Addresses IX Färm, Gunilla Örebro University Hospital Örebro Fischer, Torkel Hensvik Herräng Flyvholm, Mari-Ann National Institute of Occupational Health Lersö Parkallé Copenhagen Denmark Freeman, Susanne Skin and Cancer Foundation Contact and Occupational Clinic 277 Bourke Street, Darlinghurst 2101 Sydney Australia Goh, Chee Leok National Skin Centre (S) 1 Mandalay Road Singapore Singapore Goossens, An UZKU Leuven 3000 Leuven Belgium
9 X Addresses Gruvberger, Birgitta Department of Occupational and Environmental Dermatology Malmö University Hospital Malmö Guin, Jere D. 18 Corporate Hill Drive, Suite 100 Little Rock, AR USA Hannuksela, Matti South Karelia Central Hospital Laihiankatu 6, Lappeenranta Finland Hansson, Christer University Hospital Lund Hindsén, Monica Department of Occupational and Environmental Dermatology Malmö University Hospital Malmö Isaksson, Marléne Department of Occupational and Environmental Dermatology Malmö University Hospital Malmö
10 Addresses XI Jolanki, Riitta Finnish Institute of Occupational Health Topeliuksenkatu 41 aa Helsinki Finland Lachapelle, Jean-Marie Louvain University, UCL 3033, 30 Clos Chapelle-aux-Champs 1200 Brussels Belgium Lidén, Carola Department of Occupational and Environmental Dermatology Norrbacka Stockholm Maibach, Howard I. University of California San Francisco School of Medicine San Francisco, CA USA Möller, Halvor Malmö University Hospital Malmö Paulsen, Evy Odense University Hospital 5000 Odense C Denmark
11 XII Addresses Seidenari, Stefania University of Modena Via del Pozzo Modena Italy Shaw, Stephanie Culverton, 110, Wycombe Road Princes Risborough Bucks HP27 OEY United Kingdom Wilkinson, John Culverton, 110, Wycombe Road Princes Risborough Bucks HP27 OEY United Kingdom
12 Contents Metals Cobalt Chloride 3 Torkel Fischer Nickel Sulfate 7 Carola Lidén Potassium Dichromate 11 Christian Avnstorp Rubber Chemicals Thiuram Mix, Mercapto Mix, and Mercaptobenzothiazole 15 Christer Hansson Preservatives Diazolidinyl Urea, Imidazolidinyl Urea, and Quaternium John Wilkinson, Stephanie Shaw Formaldehyde 29 Mari-Ann Flyvholm Methylchloroisothiazolinone and Methylisothiazolinone 37 Birgitta Gruvberger Methyldibromoglutaronitrile 41 Birgitta Gruvberger, Magnus Bruze
13 XIV Contents Parabens 45 Susanne Freeman Thimerosal 47 Halvor Möller Perfumes Balsam of Peru (Myroxylon pereirae) 53 and Fragrances Derk P. Bruynzeel Fragrance Mix 57 Derk P. Bruynzeel Corticosteroids Budesonide, Tixocortol Pivalate, and Hydrocortisone-17-Butyrate 63 Marléne Isaksson Additional Benzocaine 73 Topical Remedies Stefania Seidenari Cetylstearyl Alcohol 75 Matti Hannuksela Clioquinol 79 Jean-Marie Lachapelle Ethylenediamine Dihydrochloride 81 Susanne Freeman Neomycin Sulfate 83 An Goossens Propylene Glycol 85 Mahbub M. U. Chowdhury, Howard I. Maibach Wool Alcohols 89 An Goossens
14 Contents XV Plants Colophony 93 Gunilla Färm Primin 95 Monica Hindsén Sesquiterpene Lactone Mix 97 Evy Paulsen, Klaus E. Andersen Urushiol 101 Jere D. Guin Miscellaneous Epoxy Resin 105 Riitta Jolanki, Kristiina Alanko para-phenylenediamine Free Base 111 Stefania Seidenari p-tertiary-butylphenol Formaldehyde Resin 113 Chee Leok Goh Tosylamide/Formaldehyde Resin 115 Carola Lidén
15 Alphabetized Listing of Contents Balsam of Peru (Myroxylon pereirae) 53 Benzocaine 73 Budesonide 63 Cetylstearyl Alcohol 75 Clioquinol 79 Cobalt Chloride 3 Colophony 93 Diazolidinylurea 23 Epoxy Resin 105 Ethylenediamine Dihydrochloride 81 Formaldehyde 29 Fragrance Mix 57 Hydrocortisone 17-Butyrate 63 Imidazolidinyl Urea 23 Mercaptobenzothiazole 15 Mercapto Mix 15 Methylchloroisothiazolinone and Methylisothiazolinone (MCI/MI) 37 Methyldibromoglutaronitrile 41 Neomycin Sulfate 83 Nickel Sulfate 7 Parabens 45 para-phenylenediamine Free Base 111 Potassium Dichromate 11 Primin 95 Propylene Glycol 85 p-tertiary-butylphenol Formaldehyde Resin 113 Quaternium 15 (Dowicil 200) 23
16 Alphabetized Listing of Contents XVII Sesquiterpene Lactone Mix 97 Thimerosal 47 Thiuram Mix 15 Tixocortol Pivalate 63 Tosylamide/Formaldehyde Resin 115 Urushiol 101 Wool Alcohols 89
17 Recommended Patch-test Concentrations Allergen-patch- TRUE test tape (μg/cm 2 ) Balsam of Peru 25% pet. 800 Benzocaine 5% pet. Budesonide 0.01% pet. 2 Cetylstearyl alcohol 20% pet. Clioquinol 5% pet. 190 (mix) Cobalt chloride 1% pet. 20 Colophony 20% pet. 1,200 Diazolidinyl Urea 2% pet. 600 Epoxy resin 1% pet. 50 Ethylenediamine dihydrochloride 1% pet. 50 Formaldehyde 1% aq. 180 Fragrance mix 8% pet. 430 Hydrocortisone-17-butyrate 1% ethanol 25 Imidazolidinyl urea 2% pet. 600 Mercapto mix 1 2% pet. 75 Mercaptobenzothiazole 1 2% pet. 75 Methylchloroisothiazolinone % aq. 4 and methylisothiazolinone Methyldibromoglutaronitrile % pet. 10 Neomycin sulfate 20% pet. 230
18 Recommended patch-test concentrations XIX Allergen-patch TRUE test tape (μg/cm 2 ) Nickel sulfate 5% pet. 200 Paraben mix 16% pet. 1,000 para-phenylenediamine free base 1% pet. 90 Potassium dichromate 0.5% pet. 23 Primin 0.01% pet. Propylene glycol 5% pet., 20% aq. Not finally stated p-tertiary-butylphenol 1% pet. 45 formaldehyde resin Quaternium 15 1% pet. 100 Sesquiterpene lactone mix 0.1% pet. Thimerosal 0.1% pet. 8 Thiuram mix 1% pet. 25 Tixocortol pivalate 0.1% pet. 20 Tosylamide/formaldehyde resin 10% pet. Urushiol μg in 5 μl acetone. Open test Wool alcohols 30% pet. 1,000 aq. aqueous, pet. in petrolatum.
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