The Way Forward. Allergy Autoimmune Urinalysis Infectious Disease. International Diagnostic Products Catalogue

Transcription

1 The Way Forward Allergy Autoimmune Urinalysis Infectious Disease International Diagnostic Products Catalogue

2 We are at your service. The Way Forward with a New Attitude and Increased Global Vision The new HYCOR is providing answers for allergy care and new insights into autoimmune disorders based on a long history of global R&D and manufacturing capabilities. As part of the Linden family of companies, HYCOR is building an ever stronger and intelligent organization to address the healthcare challenges we all face. We are expanding expertise in the area of allergy, autoimmune, urinalysis and infectious disease in order to provide more cost-effective laboratory based solutions that result in better patient outcomes. It is important for us to maintain a dialogue with you, our valued customers. We invite you to go to and You Tube: for up-to-date information on our products and trends in the industry. HYCOR here for you today Addressing the demands of the healthcare systems of tomorrow. Do you have questions regarding our products?* Do not hesitate to contact us. Customer Service: Toll Free Telephone (0) Toll Free Fax Fax (0) cseurope@hycorbiomedical.com Technical Service: Toll Free Telephone (0) Toll Free Fax Fax (0) techserviceseurope@hycorbiomedical.com * NOTE: This catalogue is not intended for use in the USA.

3 HYCOR Product Catalogue Table of Contents Automation HYTEC 288 System The Automated EIA System for Your Modern Diagnostics... 2 HYTEC 288 System... 3 Accessories... 3 Allergy Automated Allergy Diagnostics Using the HYTEC 288 System... 4 Specific IgE ELISA and Total IgE ELISA... 4 Specific IgG ELISA... 4 Specific IgG 4 ELISA... 5 Basic Reagents for All Allergy Applications... 5 Manual Allergy Diagnostics... 6 Manual Specific IgE ELISA... 6 Manual and Automated Allergens Using the HYTEC 288 System... 7 Allergen Discs... 7 Autoimmune AUTOSTAT II ELISA Microplate Assay Kits... 8 Thyroid Autoantibodies... 8 Rheumatology... 8 Thrombosis... 9 ANCA/Vasculitis... 9 Gastroenterology... 9 Other... 9 Basic Reagents for Autoimmune Applications... 9 Urinalysis KOVA Plastics KOVA Slides KOVA System Components KOVA Controls KOVA-Trol KOVA Liqua-Trol KOVA Stain KOVA System Pacs Urinalysis Literature (Educational Materials) Infectious Disease (Serology) ELISA (HRP), Microplates Respiratory Gastrointestinal Herpes Family Mycosis Ticks Vaccination Titers Other Basic Reagents for Infectious Disease (Serology) HYSORB Kit (RF-Absorbance)

4 Automation HYTEC 288 System The Automated EIA System for Your Modern Diagnostics Advanced Ease-of-Use due to true walk-away operation High Throughput up to 50 patients for allergy and up to 105 patients for autoimmune High Efficiency because of simultaneous processing of Specific and Total IgE in one test run or combination of up to 8 different autoimmune parameters Fast Technical Service due to remote maintenance per modem Low Rate of Personnel Expenditure due to intuitive operating software as well as fast loading of the system Easy Reagents Logistics due to long shelf-life of the reagents Professional Data Processing due to bi-directional LIS interface access See the HYTEC 288 System demo at youtube.com/hycorchannel 2

5 Automation HYTEC 288 System Fully Automated Immunoassay System for the performance of ELISA for the diagnosis of allergies, autoimmune antibodies and user defined ELISA tests. DESCRIPTION PART NO. HYTEC 288 System 74000P Accessories DESCRIPTION PKG.CONTENTS/SIZE PART NO. HYTEC 288 Autoimmune Upgrade Kit Mictrotitre Plate Adapter 3 x Wash Buffer Bottle (Standard) Wash Buffer Bottle (Cardiolipin) Reagent Rack Sample/Reagent Rack Dilution Rack HYTEC 288 Autoimmune Reagent Bottle Kit Bottle for Conjugate (60 ml) 4 x Bottle for Substrate (60 ml) 4 x Uncoated Microplate Zero Calibrator Rack R Allergen Disc Rack Bottle Top Holder Uncoated Microplates (Autoimmune Application) Sample Diluent Bottles (125 ml) Bottles for Conjugate and Substrate (60 ml) Conjugate Vials (15 ml) Control Vials (2 ml) Calibrator Vials (4 ml) HYTEC 288 Tubes (9 x 45 mm) Precision Kit Probe Cleaning Kit Probe Cleaning Solution (480 ml) Empty bottle (30 ml)

6 Allergy Automated Allergy Diagnostics Using the HYTEC 288 System Free patient brochures at brochures.html All HYCOR allergy assays are performed with serum. You can test all listed assays using our HYTEC 288 Automated Immunoassay System. Specific IgE and Total IgE ELISA For the diagnosis of a Type I Allergy (immediate type reaction) Specific IgE and Total IgE can be tested within the same HYTEC 288 System run using the same reagents The calibrator set contains 5 standards ( IU/mL) which are calibrated to the WHO reference preparation 2nd IRP 75/502. The extended calibrator set provides an additional zero level calibrator to have higher sensitivity below 0.35 IU/mL A stored reference curve is valid for 30 days Alkaline Phosphatase (AP)/pNPP are used as detection system Total IgE values will be expressed up to 2000 IU/mL Specific IgE results are reported in 6 RAST classes RAST Class Specific IgE (IU/mL) Negative < 0.35 Class I Class II Class III Class IV Class V Class VI > 100 DESCRIPTION PKG. CONTENTS/SIZE PART NO. Specific/Total IgE EIA Kit* IgE Conjugate 29 ml for 500 tests IgE Sample Diluent 100 ml IgE Reference Discs IgE Calibrator Set 5 levels IgE Extended Calibrator Set 6 levels IgE Control (positive, negative) 4 x 2 ml * Reference Discs, Calibrator Set and Control not included. Specific IgG ELISA For the diagnosis of a Type III Allergy (immune complexes) and monitoring of an immunotherapy. The calibrator set contains 4 standards ( ng/ml) which are calibrated to the WHO reference preparation 1st IRP 67/86 A stored reference curve is valid for 30 days Alkaline Phosphatase (AP)/pNPP are used as detection system Results are reported in µg/ml DESCRIPTION PKG. CONTENTS/SIZE ORDER NO. Specific IgG ELISA Kit* Specific IgG Conjugate 8 ml for 100 tests IgG Sample Diluent 80 ml IgG Reference Discs IgG Calibrator Set 4 levels Specific IgG Control (positive) 1 x 0.5 ml * Reference Discs, Calibrator Set and Control not included. 4

7 Allergy Specific IgG 4 ELISA For monitoring of an immunotherapy and for research purposes. The calibrator set contains 4 standards ( ng/ml) Alkaline Phosphatase (AP)/pNPP are used as detection system Results are reported in µg/ml DESCRIPTION PKG. CONTENTS/SIZE ORDER NO. Specific IgG 4 ELISA Kit* IgG 4 Reference Discs coated with anti-igg H IgG 4 Calibrator Set 4 levels * Reference Discs, Calibrator Set and Control not included. Basic Reagents for All Allergy Applications DESCRIPTION PKG. CONTENTS/SIZE PART NO. Substrate Diluent 125 ml Substrate Tablets (pnpp) Wash Solution Concentrate (15 x) 1000 ml Allergy Stop Solution (1 N NaOH) 1000 ml HYTEC Tubes (9 x 45 mm)

8 Allergy Manual Allergy Diagnostics Do you have smaller numbers of allergy tests? In this case, our test kits for manual allergy diagnostics (application in tubes or microplates) will be the right choice for you. Manual Specific IgE ELISA For the diagnosis of a Type I Allergy. The calibrator set contains 5 standards ( IU/mL) which are calibrated to the WHO reference preparation 2nd IRP 75/502 Alkaline Phosphatase (AP)/pNPP are used as detection system Specific IgE results are reported in 6 RAST classes: RAST Class Specific IgE (IU/mL) Negative Class I Class II Class III Class IV Class V Class VI < 0.35 IU/mL IU/mL IU/mL IU/mL IU/mL IU/mL > 100 IU/mL DESCRIPTION PKG. CONTENTS/SIZE PART NO. Specific/Total IgE EIA Kit* IgE Reference Discs IgE Calibrator Set 5 levels IgE Control (positive, negative) 4 x 2 ml * Contains apart from the conjugate the basic reagents 6

9 Allergy Manual and Automated Allergens Using the HYTEC 288 System The same allergen discs can be used for all three applications: Specific IgE, IgG and IgG 4. Allergen Discs From A like Acacia to Z like Zucchini HYCOR offers a broad spectrum of allergens. All allergen matrixes use three dimensional cellulose discs on which characterized allergen extracts are bound covalently. This guarantees a good stability and long shelf-life. DESCRIPTION PKG. CONTENTS/SIZE PART NO. Routine Allergen Discs 20 74xxx Routine Multi- and Special Allergen Discs 20 74xxx Non-Routine Allergen Discs 10 74/8xxxx Non-Routine Multi- and Special Allergen Discs 10 74/8xxxx Recombinant Allergens 10 74/8xxxx Go to for the new International Allergen Listing booklet 7

10 Autoimmune AUTOSTAT II ELISA Microplate Assay Kits HYCOR offers more than 30 parameters for the diagnosis of human autoimmune diseases. Our AUTOSTAT II ELISA kits can be performed manually or on an automated system (e.g. HYTEC 288 System). Serum is used as specimen for all AUTOSTAT II ELISA. All reagents provided with the kit are ready to use, only the wash buffer is provided as a concentrate. The microplate supplied contains 12 strips of 8 breakapart wells for your highest convenience Horseradish Peroxidase (HRP)/TMB are used as detection system The parameters marked with * are intended for the manual application only The parameters marked with are also completely validated on the DYNEX DSX instruments Free Autoantibody Map poster at The big advantage of the HYTEC 288 System: Up to 8 different autoimmune parameters can be combined in one run. Thyroid Autoantibodies Anti-Thyroid Peroxidase (TPO) 96 FGA04 Anti-Thyroglobolin (TG) 96 FGA03 Rheumatology Anti-Nuclear Antibodies Screen (ANA) 96 FGA21 ENA-6 Screen Extractable Nuclear Antigens 96 FGA14 ENA-6 (Confirmation) Tests ENA-6-Profile* (16 cavities each for all of the six antigens) 96 FGA38 Anti-Sm Smith 96 FGA31 Anti-SS-A Ro 96 FGA29 Anti-SS-B La 96 FGA30 Anti-Sm / RNP Ribonuclear Protein 96 FGA32 Anti-Scl-70 DNA Topoisomerase I 96 FGA34 Anti-Jo-1 Histidyl-tRNA-Synthetase 96 FGA33 DNA Autoantibodies Anti-dsDNA Anti-double-stranded DNA 96 FGA01 Anti-ssDNA Anti-single-stranded DNA 96 FGA02 Rheumatoid Factor Autoantibodies Total Rheumatoid Factor 96 FGA08 Rheumatoid Factor IgA 96 FGA06 Rheumatoid Factor IgG 96 FGA07 Rheumatoid Factor IgM 96 FGA05 8

11 Autoimmune Circulating Immune Complexes Circulating Immune Complex (CIC) C1q 96 FGA27 Circulating Immune Complex (CIC) C3d* 96 FGA28 Thrombosis Phospholipid Autoantibodies Anti-Cardiolipin Screen 96 FGA18 Anti-Cardiolipin Isotype* (IgA, IgG, IgM) 96 FGA37 Anti-Cardiolipin IgG 96 FGA15 Anti-Cardiolipin IgM 96 FGA16 Anti-ß2-Glycoprotein-I IgA 96 FGA24 Anti-ß2-Glycoprotein-I IgG 96 FGA22 Anti-ß2-Glycoprotein-I IgM 96 FGA23 Anti-Phosphatidyl Serine Isotype (IgG, IgM) 96 FGA35 ANCA/Vasculitis Anti-MPO p-anca Myeloperoxidase 96 FGA12 Anti-Pr-3 c-anca Proteinase-3 96 FGA11 Glomerular Basement Membrane (GBM) 96 FGA13 Gastroenterology Coeliac Diasease Autoantibodies Anti-Gliadin IgG 96 FGA19 Anti-Gliadin IgA 96 FGA20 Other Anti-Gastric Parietal Cell 96 FGA10 Anti-Mitochondrial (M2) 96 FGA09 Basic Reagents for Autoimmune Applications Only required for the HYTEC 288 application. DESCRIPTION PKG. CONTENTS/SIZE PART NO. Substrate Solution (TMB) 15 ml KLA HYTEC Tubes (9 x 45 mm) Autoimmune Stop Solution (0.25 M H 2 SO 4 ) 1000 ml D26L1000 Autoimmune Wash Buffer (Standard) 1000 ml D17L1000 Autoimmune Wash Buffer (Cardiolipin) 1000 ml D50L

12 Urinalysis KOVA Urinalysis Systems You need standardized results in your routine urinalysis? Our KOVA system offers you techniques and products for this challenge. The system cares about constant volumes, uniformity, and hygienics from sampling and transport to the analysis of the urine sediment using a microscope. The control substances KOVA-Trol can be used for the more extended quality control of physical and chemical tests as well as microscopic analysis. Join Urinalysis User Group at KOVA Plastics KOVA Slides Not only usefull for urine sediment examination, you can also use it for cell counting and other applications. DESCRIPTION PKG. CONTENTS/ PART NO. NO. of DETERMINATIONS KOVA Slide II with counting grids E KOVA Slide II without counting grids E KOVA Glasstic Slide E KOVA Glasstic Slide E KOVA Glasstic Slide 10 with counting grids E KOVA System Components DESCRIPTION PKG. CONTENTS/ PART NO. NO. of UNITS KOVA Super Tubes E KOVA Economy Tubes E KOVA Petters E KOVA Caps E KOVA Decanting Rack E KOVA Controls KOVA-Trol KOVA-Trol is a stable human urine control (freeze-dried) for complete quality control of physical chemical and microscopic examination of urine specimens. All constituents are stable for 5 days after reconstitution. Available in three levels to monitor the entire decision ranges for reagent strip chemistries. DESCRIPTION: CONTROL RANGE PKG. CONTENTS/ PART NO. NO. of UNITS KOVA-Trol I: High Abnormal 4 x 15 ml 87329E KOVA-Trol I: High Abnormal 4 x 60 ml 87325E KOVA-Trol I: High Abnormal 10 x 60 ml 87326E KOVA-Trol I: High Abnormal with Urobilinogen 4 x 60 ml 87332E KOVA-Trol I: High Abnormal with Urobilinogen 10 x 60 ml 87333E KOVA-Trol I: High Abnormal with Urobilinogen 4 x 15 ml 87334E KOVA-Trol II: Low Abnormal 4 x 15 ml 87130E KOVA-Trol II: Low Abnormal 10 x 60 ml 87128E KOVA-Trol III: Normal with hcg 4 x 15 ml 87331E KOVA-Trol III: Normal with hcg 4 x 60 ml 87327E 10

13 Urinalysis KOVA Controls (continued) KOVA Liqua-Trol KOVA Liqua-Trol is a ready-to-use liquid urine control for complete quality control of physical and chemical examination of urine specimens. Liqua-Trol is available with or without microscopics. Liqua-Trol has 30-day room temperature stability. DESCRIPTION: CONTROL RANGE PKG. CONTENTS/ PART NO. NO. of UNITS KOVA Liqua-Trol Level I: Abnormal; Level II: Normal with hcg 6 x 15 ml 87112E KOVA Liqua-Trol Level II: Normal with hcg and Microscopics 2 x 120 ml 87122E KOVA Liqua-Trol Level I: Abnormal with Microscopics 2 x 120 ml 87176E KOVA Liqua-Trol Level II: Normal with hcg and Microscopics 4 x 120 ml 87123E KOVA Liqua-Trol Level I: Abnormal with Microscopics 4 x 120 ml 87177E KOVA Stain KOVA Stain is a modified Sternheimer-Malbin stain that facilitates differentiation and enhances visualization of formed elements in urine sediment. DESCRIPTION PKG. CONTENTS/ PART NO. NO. of UNITS KOVA Stain 3 x 25 ml 87116E KOVA System Pacs DESCRIPTION PKG. CONTENTS/ PART NO. NO. of DETERMINATIONS KOVA System Super Pac 1000 with caps E 100 KOVA Glasstic Slide 10 (10 chambered) 1000 KOVA Petters 1000 KOVA Super Tubes 1000 KOVA Caps KOVA System Pac II E 100 KOVA Slide II (4 chambered) 400 KOVA Petters 400 KOVA Super Tubes KOVA System Value Pac E 50 KOVA Glasstic Slide 10 (10 chambered) 500 KOVA Petters 500 KOVA Economy Tubes KOVA System Evaluation Pack E 5 KOVA Glasstic Slide 10 with Grids 10 KOVA Petters 10 KOVA Super Tubes 10 KOVA Caps KOVA KO-LEC-PAC E 500 KOVA Super Tubes 500 KOVA Cups 500 KOVA Caps 5 Transport Racks KOVA System Super Pac E 100 KOVA Glasstic Slide 10 (10 chambered) 1000 KOVA Petters 1000 KOVA Super Tubes KOVA System Super Pac 1000 with counting grids E 100 KOVA Glasstic Slide 10 with Grid (10 chambered) 1000 KOVA Petters 1000 KOVA Super Tubes Urinalysis Educational Material (English) DESCRIPTION NO. of UNITS PART NO. A Primer for Microscopic Urinalysis by Meryl H. Haber, MD

14 Infectious Disease (Serology) ELISA (HRP) Microplates HYCOR offers a broad range of infectious disease (serology) ELISA products. Serum is used as specimen for all serology ELISA. All reagents provided with the kit are ready to use, only the wash buffer is provided as a concentrate The microplate supplied contains 12 strips of 8 breakapart wells for your highest convenience. Horseradish Peroxidase (HRP)/TMB are used as detection system Respiratory DESCRIPTION PATHOGEN TEST/KIT ANALYTE PART NO. IgG IgA IgM Adenovirus Virus ADV Bordetella pertussis Bacterium BPT Influenza A Virus IFA Influenza B Virus IFB Mycoplasma pneumoniae Mycoplasm MPP Parainfluenza 1/2/3 Virus PIF1/2/3 RSV (Resp.-Syncytial-Virus) Virus RSV Gastrointestinal DESCRIPTION PATHOGEN TEST/KIT ANALYTE PART NO. IgG IgA IgM Helicobacter pylori Bacterium HEL Yersinia enterocolitica Bacterium YER Herpes Family DESCRIPTION PATHOGEN TEST/KIT ANALYTE PART NO. IgG IgA IgM EBV EA Virus EBV-EA EBV EBNA Virus EBV-EBNA EBV VCA Virus EBV-VCA Herpes 1 Virus HSV1 Herpes 2 Virus HSV2 Herpes 1/2 Virus HSV1/2 Varicella zoster Virus VAR Mycosis DESCRIPTION PATHOGEN TEST/KIT ANALYTE PART NO. IgG IgA IgM Aspergillus fumigatus Mold ASP Candida albicans Yeast CAN Ticks DESCRIPTION PATHOGEN TEST/KIT ANALYTE PART NO. IgG IgM Borrelia burgdorferi Bacterium BBG FSME / TBEV Virus FSM 12

15 Infectious Disease (Serology) Learn more at infectuous-disease.html and download the new HYCOR Infectious Disease ELISA literature Vaccination Titers (Immune Status) DESCRIPTION PATHOGEN TEST/KIT ANALYTE PART NO. IgG Diphtheria Bacterium DIP Tetanus Bacterium TET Poliomyelitis Virus POL Others DESCRIPTION PATHOGEN TEST/KIT ANALYTE PART NO. IgG IgA IgM Brucella abortus Bacterium BRU Echinococcus Parasite ECC Measles Virus MAS Mumps Virus MUM Mycobacterium tuberculosis Bacterium MBT Basic Reagents for Infectious Disease Application (Serology) Only necessary for automated Application. DESCRIPTION PKG. CONTENTS/SIZE PART NO. Substrate Solution (TMB) 15 ml Serology Stop Solution (0.25 M H2SO4) 1000 ml D17L1000 Serology Wash Buffer 2 x 500 ml Serology Sample Diluent A 60 ml Serology Sample Diluent B 60 ml (For Measles, Mumps, Varicella, Borrelia, Diphteria, Tetanus, Echinococcus) HYSORB Kit (RF-Absorbance) HYSORB eliminates easily and quickly interfering factors (Rheumafactor/IgG antibodies) from human serum. It should be applied prior to perform an ELISA for the detection of IgM antibodies to exclude false-positive results. DESCRIPTION PKG. CONTENTS/SIZE PART NO. HYSORB Kit 20 ml for 100 tests HYS

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