Head of Division, Allergology Division. Head of Allergy-Unit and Interdisciplinary Allergy Center

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1 Curriculum vitae PERSONAL INFORMATION Vera Mahler WORK EXPERIENCE February 2017 Present Head of Division, Allergology Division Paul-Ehrlich-Insitut (Germany) Regulation of test- and therapeutic allergens in Germany Research on clinically relevant aspects of allergic diseases Scientific advice (EMA and national) to pharmaceutic companies, politics and scientific/medical societies Strategic guidance of Division Cooperation with other Divisions and academic institutions November 2002 January 2017 Head of Allergy-Unit and Interdisciplinary Allergy Center Medical Training of Residents Teaching (medical students) Translational Research Steering of own research group (Experimental allergology) Aquisition of external funding Participation in Clinical studies Participation in academic societies und cooperation Projects Medical Expertises Publishing of Research results Participation in Guideline development Medical Controlling Quality management January 2000 January 2002 Fellow Medical Training of Residents Teaching (medical students) Medical Expertises Translational Research Steering of own research group (Experimental allergology) Aquisition of external funding Participation in Clinical studies Participation in academic societies und cooperation Projects Publishing of Research results Quality management January 1997 December 1999 Research Fellow Inst. for Pathophysiology and Allergy, University of Vienna (Austria) Basic research in allergy/molecular allergology 16/11/17 European Union, Page 1 / 5

2 allergen aharacterization Mouse models September 1992 August 1997 Resident (specialty training in Dermatology and Allergology) training in dermatology and the subspecialties of the field (allergology, andrology, infectious disease, occupational dermatology, oncology, phlebology, phototherapy, proctology, venerology) Board certified expert in dermatology, allergology occupational dermatology EDUCATION AND TRAINING September 1992 August 1997 Board certified expert in dermatology, allergology, occupational dermatology. Dept. of Medical education as a resident in dermatology and the subspecialties of the field (allergology, andrology, infectious disease, occupational dermatology, oncology, phlebology, phototherapy, proctology, venerology) October 1985 May 1992 Licence as a state certified physician Ruprecht-Karls-University Heidelberg (Germany) human medicine ADDITIONAL INFORMATION Expertise Clinical and molecular allergology Dermatology occupational dermatology Type I/Type IV-Allergy Clinical Studies (GCP) Medicinal products Act (Germany) Therapy Allergen ordinance Publications Allergenic and microbiological hazards caused by skin markings during medical procedures? Maronna A, Psaier S, Erfurt-Berge C, Geier J, Mahler V. J Dtsch Dermatol Ges Oct;15(10): doi: /ddg Omalizumab treatment in patients with chronic inducible urticaria: A systematic review of published evidence. Maurer M, Metz M, Brehler R, Hillen U, Jakob T, Mahler V, Pföhler C, Staubach P, Treudler R, Wedi B, Magerl M. J Allergy Clin Immunol Jul 24. pii: S (17) doi: /j.jaci [Epub ahead of print] Occupational skin diseases: actual state analysis of patient management pathways in 28 European countries. Mahler V, Aalto-Korte K, Alfonso JH, Bakker JG, Bauer A, Bensefa-Colas L, Boman A, Bourke J, Bubaš M, Bulat P, Chaloupka J, Constandt L, Danielsen TE, Darlenski R, Dugonik A, Ettler K, Gimenez-Arnau A, Gonçalo M, Johansen JD, John SM, Kiec-Swierczynska M, Koch P, Kohánka V, Krecisz B, Larese Filon F, Ljubojević S, Macan J, Marinović B, Matura M, Mihatsch PW, Mijakoski D, Minov J, Pace J, Pesonen M, Ramada Rodilla JM, Rast H, Reljic V, Salavastru C, Schuster C, Schuttelaar ML, Simon D, Spiewak R, Jurakic Tončić R, Urbanček S, Valiukevičienė S, Weinert P, Wilkinson M, Uter W. J Eur Acad Dermatol Venereol Jun;31 Suppl 4: doi: /jdv Minimum standards on prevention, diagnosis and treatment of occupational and work-related skin diseases in Europe - position paper of the COST Action StanDerm (TD 1206). Alfonso JH, Bauer A, 16/11/17 European Union, Page 2 / 5

3 Bensefa-Colas L, Boman A, Bubas M, Constandt L, Crepy MN, Goncalo M, Macan J, Mahler V, Mijakoski D, Ramada Rodilla JM, Rustemeyer T, Spring P, John SM, Uter W, Wilkinson M, Giménez- Arnau AM. J Eur Acad Dermatol Venereol Jun;31 Suppl 4: doi: /jdv European Surveillance System on Contact Allergies (ESSCA): results with the European baseline series, 2013/14. Uter W, Amario-Hita JC, Balato A, Ballmer-Weber B, Bauer A, Belloni Fortina A, Bircher A, Chowdhury MMU, Cooper SM, Czarnecka-Operacz M, Dugonik A, Gallo R, Giménez- Arnau A, Johansen JD, John SM, Kieć-Świerczyńska M, Kmecl T, Kręcisz B, Larese Filon F, Mahler V, Pesonen M, Rustemeyer T, Sadowska-Przytocka A, Sánchez-Pérez J, Schliemann S, Schuttelaar ML, Simon D, Spiewak R, Valiukevičienė S, Weisshaar E, White IR, Wilkinson SM. J Eur Acad Dermatol Venereol Sep;31(9): doi: /jdv Epub 2017 Aug 13. Skin diseases associated with environmental factors. Mahler V. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz Jun;60(6): doi: /s Review. German. Patterns of chronic hand eczema: a semantic map analysis of the CARPE registry data. Cazzaniga S, Apfelbacher C, Diepgen T, Ofenloch R, Weisshaar E, Molin S, Bauer A, Mahler V, Elsner P, Schmitt J, Ballmer-Weber BK, Spring P, Naldi L, Borradori L, Simon D; CARPE study groups of Germany and Switzerland. Br J Dermatol May 12. doi: /bjd [Epub ahead of print] House dust mite-specific immunotherapy with two licensed vaccines: Outcome under clinical routine conditions. Mahler V, Klein C, Sager A, Zimmermann J. Immun Inflamm Dis Jun;5(2): doi: /iid Epub 2017 Mar 5. Re "International survey on skin patch test procedures, attitudes and interpretation" L.K. Tanno et al., WAOJ (2016) 9:8. Uter W, Bruze M, Rustemeyer T, Orton D, Mahler V; European Society of Contact Dermatitis. World Allergy Organ J Apr 26;10(1):18. doi: /s ecollection Allergic contact dermatitis caused by a catheter system containing sodium metabisulfite. Grosch E, Mahler V. Contact Dermatitis Mar;76(3): doi: /cod No abstract available. The current spectrum of contact sensitization in patients with chronic leg ulcers or stasis dermatitis - new data from the Information Network of Departments of Dermatology (IVDK). Erfurt-Berge C, Geier J, Mahler V. Contact Dermatitis Sep;77(3): doi: /cod Epub 2017 Feb 14. H1-antihistamine-refractory chronic spontaneous urticaria: it's worse than we thought - first results of the multicenter real-life AWARE study. Maurer M, Staubach P, Raap U, Richter-Huhn G, Bauer A, Ruëff F, Jakob T, Yazdi AS, Mahler V, Wagner N, Lippert U, Hillen U, Schwinn A, Pawlak M, Behnke N, Chaouche K, Chapman-Rothe N. Clin Exp Allergy May;47(5): doi: /cea Epub 2017 Mar 2. Patch testing with rubber series in Europe: a critical review and recommendation. Warburton KL, Uter W, Geier J, Spiewak R, Mahler V, Crépy MN, Schuttelaar ML, Bauer A, Wilkinson M. Contact Dermatitis Apr;76(4): doi: /cod Epub 2016 Dec 28. Review. Contact allergy to preservatives: ESSCA* results with the baseline series, Giménez-Arnau AM, Deza G, Bauer A, Johnston GA, Mahler V, Schuttelaar ML, Sanchez-Perez J, Silvestre JF, Wilkinson M, Uter W. J Eur Acad Dermatol Venereol Apr;31(4): doi: /jdv Epub 2017 Jan 17. Statement of the German Contact Dermatitis Research Group (DKG) and the German Dermatological Society (DDG) on liability issues associated with patch testing using a patient's own materials. Mahler V, Dickel H, Diepgen TL, Hillen U, Geier J, Kaufmann R, Kreft B, Schnuch A, Szliska C, Bender A. J Dtsch Dermatol Ges Feb;15(2): doi: /ddg Epub 2016 Oct 28. No abstract available. Contact allergy to sulfites: clinical and occupational relevance - new data from the German Contact Dermatitis Research Group and the Information Network of Departments of Dermatology (IVDK). Häberle M, Geier J, Mahler V. J Dtsch Dermatol Ges Sep;14(9): doi: /ddg No abstract available. Limited availability of diagnostic allergens for patch testing compromises patient care. Mahler V, Schnuch A, Bauer A, Werfel T, Strömer K, Enk A, Bieber T, Klimek L. J Dtsch Dermatol Ges Jul;14(7): doi: /ddg No abstract available. Does a short patch test training course have an impact? Uter W, Gefeller O, Mahler V. Contact Dermatitis May;74(5): doi: /cod Persistence of the IgE repertoire in birch pollen allergy. Otte M, Mahler V, Kerpes A, Pabst O, Voehringer D. J Allergy Clin Immunol Jun;137(6): e8. doi: /j.jaci Epub 2016 Apr 20. No abstract available. Hand dermatitis--differential diagnoses, diagnostics, and treatment options. 16/11/17 European Union, Page 3 / 5

4 Mahler V. J Dtsch Dermatol Ges Jan;14(1):7-26; quiz doi: /ddg Which factors are associated with the use of systemic antihistamines in patients with chronic hand eczema? Results from the CARPE registry. Apfelbacher C, Weiß M, Molin S, Bauer A, Mahler V, Schmitt J, Elsner P, Diepgen TL, Weisshaar E. J Eur Acad Dermatol Venereol Jan;30(1):50-6. doi: /jdv Epub 2015 Oct 14. DKG statement on the use of metal alloy discs for patch testing in suspected intolerance to metal implants. Thomas P, Geier J, Dickel H, Diepgen T, Hillen U, Kreft B, Schnuch A, Szliska C, Mahler V. J Dtsch Dermatol Ges Oct;13(10): doi: /ddg The public health issue of allergic contact Dermatitis. Schnuch A, Mahler V. Hautarzt Sep;66(9): doi: /s y. German. Nickel and cobalt release from metal alloys of tools--a current analysis in Germany. Kickinger-Lörsch A, Bruckner T, Mahler V. Contact Dermatitis Nov;73(5): doi: /cod Epub 2015 Aug 21. Contact allergies in the elderly. Mahler V. Hautarzt Sep;66(9): doi: /s z. German. Dihydroxydiphenyl - a historical rubber contact allergen? Frosch PJ, Mahler V, Uter W. Contact Dermatitis Dec;73(6): doi: /cod Epub 2015 Jul 31. Contact allergies in the German workforce: Data of the IVDK network from ]. Bauer A, Geier J, Mahler V, Uter W. Hautarzt Sep;66(9): doi: /s European Society of Contact Dermatitis guideline for diagnostic patch testing - recommendations on best practice. Johansen JD, Aalto-Korte K, Agner T, Andersen KE, Bircher A, Bruze M, Cannavó A, Giménez-Arnau A, Gonçalo M, Goossens A, John SM, Lidén C, Lindberg M, Mahler V, Matura M, Rustemeyer T, Serup J, Spiewak R, Thyssen JP, Vigan M, White IR, Wilkinson M, Uter W. Contact Dermatitis Oct;73(4): doi: /cod Epub 2015 Jul 14. Patch test results with fragrance markers of the baseline series - analysis of the European Surveillance System on Contact Allergies (ESSCA) network Frosch PJ, Duus Johansen J, Schuttelaar ML, Silvestre JF, Sánchez-Pérez J, Weisshaar E, Uter W; ESSCA network. Contact Dermatitis Sep;73(3): doi: /cod Epub 2015 Jun 16. Projects COST Action 1206 Standerm Information Network of Departments of Dermatology (IVDK) European Surveillance System on Contact Allergies (ESSCA) Network of severe allergic reactions (NORA) European Academy of Allergy Clinical Immunology Task Forces on -Adiuvants in AIT, -Health economics in Allergy Treatment, -AIT in Children, -Patch Testing. Memberships European Society of Contact Dermatitis (ESCD) (Member of the Executive committee) European Academy of Allergology and Clinical Immunology (EAACI) (Task Force Member) Deutsche Kontaktallergie Gruppe (DKG) (Member of the Executive committee) Deutsche Dermatologische Gesellschaft (DDG) Arbeitsgemeinschaft Dermatologische Forschung (ADF) Arbeitsgemeinschaft für Berufs- und Umweltdermatologie (ABD) (member of the working Party on occupational allergen exposure) Deutsche Gesellschaft für Allergologie und klinische Immunologie (DGAKI)(Advisory board) Arbeitskreis Psychosomatische Dermatologie Arbeitskreis Dermatologischer Diagnosenkatalog (DDK) Other Relevant Information 16/11/17 European Union, Page 4 / 5

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