Internship: Columbia Presbyterian Medical Center 6/89-6/90 Internal Medicine New York, New York
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1 Name: Address: Angela DiMango, M.D. The New York Presbyterian Hospital Columbia University Medical Center 161 Fort Washington Avenue; Third Floor New York, NY Phone: (212) FAX: (212) Education: B.A. 5/84 M.D. 5/89 New York University, magna cum laude SUNY Health Science Center Brooklyn, New York Licensure: New York # Traineeship: Internship: Columbia Presbyterian Medical Center 6/89-6/90 Internal Medicine Residency: Columbia Presbyterian Medical Center 7/90-6/92 Internal Medicine Fellowship: Pulmonary/Critical Care Medicine 7/93-6/96 Columbia Presbyterian Medical Center Board Certification: National Board of Medical Examiners 1990 American Board of Internal Medicine 1993, 2004, 2014 Pulmonary Medicine 1995, 2005, 2015 Critical Care Medicine 1996
2 Professional Organizations: American College of Chest Physicians American Thoracic Society 1996-present Society of Clinical Practioners 1996-present Academic Appointments: Columbia University Instructor in Clinical Medicine Assistant in Clinical Medicine Assistant Professor of Clinical Medicine Associate Professor of Clinical Medicine 2012-present Assistant Director, Adult Cystic Fibrosis Program Hospital Appointments Coumbia Presbyterian Medical Center/ New York Presybterian Hospital Assistant Physician Clinical Assistant Physician Assistant Attending Physician Associate Attending Physican present Awards: Phi Beta Kappa, New York University 1983 Alpha Omega Alpha, SUNY Downstate Medical Center 1988 Fellow Teaching Award in Pulmonary Medicine 1994 Junior Faculty Teaching Award in Pulmonary Medicine 1997 Ewig Clinical Scholar Educational Award, Columbia University 2010
3 Teaching Responsibilities Pulmonary Consultation Service, New York Presbyterian Hospital Lung Transplant Service/New York Presbyterian Hospital 1996-present 2003-present Preceptor for second-year Medical School Pulmonary Pathophysiology Course Preceptor for First Year Medical School Students 2009-present Academic Service Elected Representative, Faculty Practice Organization Clinical Trials, Active, Site Principal Investigator Bronchiectasis and NTM Research Registry/COPD Foundation Principal Investigator The Bronchiectasis Research Registry is a consolidated database of non-cystic fibrosis (non-cf) Bronchiectasis and Non tuberculosis Mycobacteria (NTM) patients from multiple tertiary institutions. INS-212 LAI Trial A Randomized, Open-label, Multicenter Study of Liposomal Amikacin for Inhalation (LAI) in Adult Patients With Nontuberculous Mycobacterial (NTM) Lung Infection Caused by Mycobacterium Avium Complex (MAC) That Are Refractory to Treatment. Parion CLEAN-PCD A Phase 2a, 2-part,Randomized, Double-blind, Placebo-controlled, Incomplete Block Crossover Study to Evaluate the Safety and Efficacy of VX-371 Solution for Inhalation With and Without Oral Ivacaftor in Subjects With Primary Ciliary Dyskinesia. Previous Clinical Trials Aradigm Orbit 4 Trial- Principal Investigator 2015 Trial is a Phase III international research study to test the safety and effectiveness of the investigational drug known as Pulmaquin compared to
4 placebo in non-cystic fibrosis bronchiectasis patients with chronic Pseudomonas aeruginosa lung infections. Gilead Sciences Principal Investigator AIR-BX2 Trial. A Phase 3, Double-Blind, Multicenter Randomized Placebo Controlled Trial Evaluating Repeated 2011 Courses of Aztreonam for Inhalation in Subjects with Non CF Bronchiectasis ARRA noa: RO1 HS Data Monitor 2010 Effect of environmental remediation on need for pharmacologic Therapy in asthma National Heart Lung and Blood Institute, Consultant 2010 (subcontract Brigham and Women s Hospital) KIA (ckit inhibition in asthma) Gilead Sciences Principal Investigator Open-Label, Multicenter Trial to Validate the Quality of Life Questionnaire in Bronchiectasis and to Evaluate perception of Symptom Improvement Following One Course of Aztreonam for Inhalation Solution In Subjects with Bronchiectasis GS-US Spiration, Inc. Sub-Investigator Intrabronchial one way valve placement in Patients with Emphysema Broncus Technologies, Inc Drug Eluting Stent for Airway Bypass 2007 Co-Investigator NHLBI Asthma Clinical Research Network 5U10HL Macrolides in Asthma Consultant Inspire Pharmaceuticals Denufosol Tetrasodium (INS37217) Inhalation Solution for 10/06-4/09 Cystic Fibrosis Agcy#: INSPHARM Co-Investigator
5 Corus Pharmaceuticals (now Gilead Sciences) 12/05-6/08 Phase 3 Open Label, Follow-On Study of Multiple Courses of Aztreonam Lysinate for Inhalation in Cystic Fibrosis Patient Corus 6. Co-Investigator National Emphysema Treatment Trial (NETT) 1997 Co-Investigator Publications Melanie A. Ruffner, MD,PhD, Timothy R. Aksamit, MD, Byron Thomashow, MD, Radmila Choate, MPH, Angela DiMango, MD, Gerard M. Turino, MD, Anne E. O Donnell, MD, Margaret M. Johnson, MD, Kenneth N. Olivier, MD, MPH, Kevin Fennelly, MD, Charles L. Daley, MD, KevinL.Winthrop, MD, MPH, Mark L. Metersky, MD, Matthias A. salathe, MD, Michael R. Knowles, MD, M. Leigh Anne Daniels, MD, MPH, Peadar G. Noone, MD, Gregory Tino, MD, David E. Griffith, MD, Kathleen E. Sullivan, MD, PhD. Frequency of untreated hypogammaglobulinemia in bronchiectasis. Annals of Allergy, Asthma & Immunology, 2017, 119(1): Ginsburg, Mark E, Thomashow, Byron M, Yip, Chun K, DiMango, Angela M, Maxfield, Roger A, Bartels, Matthew N, Jellen, Patricia, Bulman, William A, Lederer, David, Brogan, Francis L, Gorenstein, Lyall A, Sonett, Joshua R The Annals of Thoracic Surgery, 2011, ISSN: , Volume 91, Issue 5, p Washko GR, Fan VS, Ramsey SD, Mohsenifar Z, Martinez F, Make BJ, et al, for the National Emphysema Treatment Trial Research Group: The effect of lung volume reduction surgery on chronic obstructive pulmonary disease exacerbations. Am J Respir Crit Care Med; 177: , Lederer DJ, Thomashow BM, Ginsburg ME, Austin JHM, Bartels MN, Yip CK, Jellen PA, Brogan FL, Kawut SM, Maxfield RA, DiMango AM, Simonelli PF, Gorenstein LA, Pearson GDN, Sonett JR. Lung volume reduction surgery for pulmonary emphysema: Improvement in the BODE index after 1 year. J Thorac Cardiovasc Surg 2007;133(6): National Emphysema Treatment Trial Research Group: A Randomized Trial Comparing Lung-Volume-Reduction Surgery with medical therapy for severe emphysema. N Engl J Med; 348: , 2003.National Emphysema Treatment Trial Research Group. Rationale and design of the National Emphysema Treatment Trial (NETT): A prospective randomized trial of lung volume reduction. Chest 1999; 116: DiMango, A.M., Schulman, L., McGregor, C., Simonelli, P.F. Expression of Transforming Growth Factor-beta (TGF-ß) RNA by bronchoalveolar cells obtained from lung transplant recipients. Chest :126S. Slide Presentation-ACCP Meeting 11/95. (Alfred Soffer Research Award Finalist) DiMango, A.M., Schulman, L., McGregor, C., Simonelli, P.F. Expression of Transforming Growth Factor-beta (TGF-ß) RNA by bronchoalveolar cells obtained from lung transplant
6 recipients. Chest :126S. Slide Presentation-ACCP Meeting 11/95. (Alfred Soffer Research Award Finalist) DiMango, A.M., Schulman, L.L., McGregor, C., Tester, W., and Simonelli, P.F. Transforming growth factor (TGF)ß1 RNA expression by bronchoalveolar lavage cells obtained from lung transplant recipients is increased during periods of acute rejection. Am. J. Resp. Crit. Care Med :A151. AM DiMango, PF Simonelli, M.Argeniano, LA Gorenstein, KM Steinglass, ME Ginsburg, C Yip, KMPrager, B. Thomashow, J. Edsall. Spirometry and exercise tolerance are significantly imporved in patients who undergo volume reduction pneumectomy for advanced emphysema. American Journal Respiratory Care (153), 1996:A449. DiMango, A.M., Schulman, L., McGregor, C., Simonelli, P.F. Expression of Transforming Growth Factor-beta (TGF-ß) RNA by bronchoalveolar cells obtained from lung transplant recipients. Chest :126S. Slide Presentation-ACCP Meeting 11/95. (Alfred Soffer Research Award Finalist) DiMango, A.M., Rogers, L. Simonelli, P.F. Determaination of gag DNA and RNA levels in bronchoalveolar lavage cells obtained from health, asymptomatic HIV-1 infected individuals. Chest :98S. Slide Presenation-ACCP Meeting 11/95/ (Cecile Lehman Mayer Research Award Finalist)
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