8/2004-5/2008 M.D., University of Wisconsin School of Medicine and Public Health 8/2000-5/2004 B.S., University of Wisconsin

Transcription

1 Jaime L. Hook, C.V., p. 1 Preparation Date 5/15/2018 Name Contact Jaime L. Hook jh3036@cumc.columbia.edu Lung Biology Laboratory Division of Pulmonary, Allergy, and Critical Care Medicine Columbia University Medical Center 630 West 168th Street, BB 8 Room 812 New York, NY Laboratory manager, Rashmi Patel: rnp2105@cumc.columbia.edu Phone: Fax: Lung Transplantation Program Division of Pulmonary, Allergy, and Critical Care Medicine Columbia University Medical Center 622 West 168th Street, PH-14 Room 104 New York, NY Administrative assistant, Maylin Rincon: mer2159@cumc.columbia.edu Phone: Fax: Birthplace Citizenship Milwaukee, WI United States of America Academic Appointments 7/2015-6/2017 Instructor in Medicine at CUMC, Columbia University Medical Center 7/2017-present Assistant Professor of Medicine, Columbia University Medical Center Hospital Appointments 7/2015-present Assistant Attending Physician, New York Presbyterian Hospital Education 8/2004-5/2008 M.D., University of Wisconsin School of Medicine and Public Health 8/2000-5/2004 B.S., University of Wisconsin Training Clinical and Research Training: 7/2013-6/2015 T32 Research Fellow, Lung Biology Laboratory, Columbia University Medical Center 7/2011-6/2014 Clinical Fellow, Pulmonary & Critical Care Medicine, Columbia University Medical Center 7/2009-6/2011 Resident, Internal Medicine, Columbia University Medical Center 6/2008-6/2009 Intern, Internal Medicine, New York University Medical Center 5/2005-8/2005 Research Fellow, Institute for Clinical and Translational Research, University of Wisconsin School of Medicine and Public Health 1

2 Jaime L. Hook, C.V., p. 2 Other Specialized Education and Training: 2014 Responsible Conduct of Research and Related Policy Issues, Columbia University Mailman School of Public Health. Course G4010. January 24 May 2, 2014; New York, NY Portable Ultrasonography Course for Fellows in Pulmonary and Critical Care Medicine, Greater New York Hospital Association. July 20-22, 2011; New York, NY. Gaps There are no gaps in my work, training, or education. Licensure and Certifications Licensure (active): 2009 Physician License, New York State (#255534) Certifications (all active): 2014 Board Certification, Critical Care Medicine, American Board of Internal Medicine (ABIM) 2013 Board Certification, Pulmonary Medicine, ABIM 2011 Board Certification, Internal Medicine, ABIM 2008 American Heart Association Advanced Cardiac Life Support Certification 2008 American Heart Association Basic Life Support Certification Honors and Awards Post-graduate: 2018 Jo Rae Wright Award in recognition of outstanding scientific achievement by a young investigator, Respiratory Cell and Molecular Biology (RCMB) Assembly, American Thoracic Society (ATS) 2018 Science and Innovation Center Abstract Award, RCMB Assembly, ATS 2016 Abstract Scholarship, RCMB Assembly, ATS 2015 Travel Award, Lung Transplant Foundation Public Advisory Roundtable in the Assembly on Allergy, Immunology, and Inflammation, ATS 2014 Abstract Award, RCMB Assembly, ATS 2014 Travel Award, Federation of American Societies for Experimental Biology 2012 Travel Award, Assembly on Clinical Problems, ATS 2010 Arnold P. Gold Foundation Award for Humanism and Excellence in Teaching, conferred by the Columbia University College of Physicians and Surgeons Class of 2012 Medical school: 2008 Alpha Omega Alpha 2008 Gold Humanism Honor Society Member 2008 University of Wisconsin Department of OB/GYN Award for Academic Excellence 2007 Wisconsin Medical Society Foundation Presidential Scholar Award for Leadership 2007 University League Endowed Scholarship for Leadership 2006 Wisconsin Medical Society Foundation General Medical Education Scholarship 2006 Wisconsin Medical Alumni Association Scholarship for Leadership 2006 Eugene M. Polo Scholarship for Dedication to Education 2005 Wisconsin Medical Society Charity Roast Scholarship 2005 Lora L. Marshall Scholarship for Academic Achievement Undergraduate: 2004 Phi Beta Kappa 2004 Graduation with Distinction (top 20% of graduating class) 2002 Beta Beta Beta Biological Honor Society Member 2000 Medical Scholar (granted pre-admission to the University of Wisconsin School of Medicine and Public Health based on high school performance) 2

3 Jaime L. Hook, C.V., p. 3 Academic Service 2016 Junior Faculty Member, Fellows Breakfast: Academic and Research Career Guidance Seminar for Department of Medicine Fellows, Columbia University Medical Center (CUMC), New York, NY 2016 Fellowship Applicant Interviewer, Pulmonary and Critical Care Fellowship Program, CUMC Professional Organizations and Societies Research meeting organizing roles: 2018 Gordon Conference and Seminar on the Biology of Acute Respiratory Infection, Ventura, CA Co-Chair, Gordon Research Seminar Organizer and Facilitator, Power Hour seminar to address challenges faced by women in science 2018 American Thoracic Society International Conference, San Diego, CA Member, Respiratory Cell and Molecular Biology Program Committee Organizer, Respiratory Cell and Molecular Biology Assembly Mentoring Program Facilitator, Epithelial Cell Biology in Respiratory Disease Thematic Poster Session American Thoracic Society roles: present Society Member present Respiratory Cell & Molecular Biology Assembly Early Career Professionals Working Group Member Wisconsin Medical Society roles: Society Member Board of Directors Member Council on the Health of the Public Member University of Wisconsin School of Medicine and Public Health Medical Student Association roles: Member President (elected by peers to serve as the primary representative of the 700-student body and lead organizer of medical student events and fundraisers) Other Professional Memberships and Positions: American Medical Association Medical Student Representative present Wisconsin Medical Alumni Association Class of 2008 Representative present American Heart Association Member present Columbia Virginia Kneeland Frantz Society for Women Faculty Member Grant Support Pending: Columbia University Irving Institute/Clinical Trials Office Pilot Award 7/1/18-6/30/19 Novel mechanisms of post-influenza staphylococcal lung injury This award supports junior investigators to obtain pilot data that will lead to independent, external funding. Role: PI ($75,000) Present: AHA Fellow-to-Faculty Transition Award (Scored in the 0.1 percentile) 7/1/16-6/30/21 Pulmonary microvascular responses to methicillin-resistant Staphylococcus aureus lung infection This career development award critically supports the transition from trainee to independent investigator. Role: PI ($593,000) 3

4 Jaime L. Hook, C.V., p. 4 Past: Competitive renewal, Stony Wold-Herbert Fund Research Training Fellowship 7/1/16-6/30/17 The goal of this Fellowship is to receive training in the investigation of respiratory diseases. This Fellowship was relinquished due to overlapping support with the AHA Award. Role: PI ($25,000) Stony Wold-Herbert Fund Research Training Fellowship 7/1/15-6/30/16 The goal of this Fellowship was to receive training in the investigation of respiratory diseases. Role: PI ($25,000) NHLBI T32 HL (J. Bhattacharya), Columbia Training Program in Lung Science 7/1/13-6/30/15 The goal of this Fellowship was to receive training in basic and translational lung biology. Role: Fellow ($103,032) Research Fellowship, UW Institute for Clinical and Translational Research 5/15/05-8/15/05 Self-rated health as a predictor of future functioning in older adults after a diagnosis of cancer The goal of this project was to receive training in clinical epidemiology research. Role: PI ($4,000) Educational Contributions Direct Teaching, Precepting, and Supervising: 2015-present Teaching and supervising attending for clinical fellows rotating on the inpatient Lung Transplant Service, Columbia University Medical Center (4 weeks/year) 2003 Teaching Assistant, Comparative Anatomy (undergraduate course no. 430, 431), Department of Zoology, University of Wisconsin (6 hours/week) Clinical and Public Health Activities Volunteer, MEDiC (student-run free clinic program), Madison, WI Co-Chair, Planning Committee, University of Wisconsin (UW) Relay for Life annual fundraiser to benefit American Cancer Society-supported research, Madison, WI Logistics Chair, Planning Committee, UW Relay for Life, Madison, WI Publications Peer-Reviewed Research Publications: Hook JL, Islam MN, Parker D, Prince AS, Bhattacharya S, Bhattacharya J. Disruption of staphylococcal aggregation protects against lethal lung injury. J Clin Invest. 2018;128(3): PMID This paper was highlighted by the journal editors in the March 2018 issue of JCI This Month, a digest of featured publications. Benvenuto LJ, Anderson DR, Kim HP, Hook JL, Shah L, Robbins HY, D Ovidio F, Bacchetta M, Sonett JR, Arcasoy SM. Geographic disparities in donor lung supply and lung transplant waitlist outcomes: a cohort study. Am J Transplant In press. PMID Hook JL, Arcasoy SM, Zemmel D, Bartels MN, Kawut SM, Lederer DJ. Titrated oxygen requirement and prognostication in idiopathic pulmonary fibrosis. Eur Respir J. 2012;39(2): PMID Hook JL, Lederer DJ. Socioeconomic barriers to lung transplantation: balancing access and equity. Am J Respir Crit Care Med. 2012;186(10): PMID

5 Jaime L. Hook, C.V., p. 5 Hook JL, Lederer DJ. Selecting lung transplant candidates: where do current guidelines fall short? Expert Rev Respir Med. 2012;6(1): PMID Published Abstracts: Hook JL and Bhattacharya J. Real-time optical imaging of MRSA-induced alveolar injury mechanisms. To be published in: ATS International Conference Abstracts, Section to be announced. May 18-23, 2018; San Diego, CA. Abstract A2465. Hook JL and Bhattacharya J. Localized alveolar-bacterial interactions determine global lung injury by Staphylococcus aureus. In: ATS International Conference Abstracts, Section B80: Mechanisms and Models of Acute Lung Injury. May 19-24, 2017; Washington, D.C. Abstract A4398. Hook JL and Bhattacharya J. Staphylococcus aureus causes mitochondrial injury in live alveoli. In: ATS International Conference Abstracts, Section B97: Mitochondrial Dysfunction in the Development of Lung Disease. May 14-18, 2016; San Francisco, CA. Abstract A4597. Hook JL, Islam MN, Westphalen K, Parker D, Prince A, Bhattacharya J. Alveolar curvatures determine Staphylococcus aureus-induced lung injury. In: ATS International Conference Abstracts, Section B101: Acute Lung Injury and Inflammation. May 15-20, 2015; Denver, CO. Abstract A3687. Hook JL, Islam MN, Westphalen K, Cohen T, Prince A, Bhattacharya J. Alveolar retention of Staphylococcus aureus. Presented at: Federation of American Societies for Experimental Biology (FASEB) Conference, The Lung Epithelium in Health and Disease. July 27 August 1, 2014; Saxtons River, VT. Abstract. Hook JL, Islam MN, Westphalen K, Cohen TS, Prince AS, Bhattacharya J. Optical imaging of bacterial clearance in live alveoli. In: ATS International Conference Abstracts, Section C18: Not Just A Job, But An Adventure: Molecular Underpinnings of Acute Lung Injury. May 17-21, 2014; San Diego, CA. Abstract A3963. Hook JL, Sonett J, Wilt J, Shah L, Robbins H, Sanyal S, et al. The frailty phenotype in lung transplantation: preliminary results. In: ATS International Conference Abstracts, Section D13: Scientific and Clinical Innovations in Lung Transplantation. May 18-23, 2012; San Francisco, CA. Abstract A5328. Hook JL, Arcasoy SM, Zemmel D, Bartels MN, Kawut SM, Lederer DJ. Gas exchange and outcome prediction in idiopathic pulmonary fibrosis. In: ATS International Conference Abstracts, Section B42: Novel Phenotypes, Outcome Measures, Treatment Strategies, and Comorbid Illness. May 13-18, 2011; Denver, CO. Abstract A1516. Hook JL, Zemmel D, Philip N, Rybak D, Koeckert M, Shah L, et al. A novel point-of-care oxygen titration study in interstitial lung disease. In: ATS International Conference Abstracts, Section B40: Interstitial Lung Disease, Epidemiology and Outcomes. May 14-19, 2010; New Orleans, LA. Abstract A2969. Hook JL and Smith MA. A longitudinal model for progressive decline leading to frailty in cancer patients. Abstract. Medical Student Summer Research Fall Forum, UWSMPH. November 17, 2005; Madison, WI. Oral Presentations at Scientific Meetings National and International Presentations: Abstract Award Presentation: Hook JL. The role of alveolar microanatomy in bacterial lung infection. Science and Innovation Center, American Thoracic Society (ATS) Conference. May 22, 2018; San Diego, CA. 5

6 Jaime L. Hook, C.V., p. 6 Mini Symposium: Hook JL. Real-time optical imaging of MRSA-induced alveolar injury mechanisms. Redefining ALI Pathogenesis, ATS Conference. May 20, 2018; San Diego, CA. Short Talk: Hook JL. Optical studies of staphylococcal antibiotic resistance mechanisms in lung alveoli. Gordon Research Conference on the Biology of Acute Respiratory Infection. March 17-23, 2018; Ventura, CA. Full-Length Presentation (Conference) and Short Talk (Seminar): Hook JL. Lung infection by Staphylococcus aureus novel mechanisms. Gordon Research Conference and Seminar on the Biology of Acute Respiratory Infection. February 20 and 22, 2016; Galveston, TX. Mini Symposium: Hook JL. Staphylococcus aureus causes localized lung alveolar injury. Mitochondrial Dysfunction in Development of Lung Disease, ATS Conference. May 23, 2016; San Francisco, CA. Poster Discussion: Hook JL. Mechanisms of alveolar retention and injury in Staphylococcus aureus lung infection. Acute Lung Injury and Inflammation, ATS Conference. May 18, 2015; Denver, CO. Short Talk: Hook JL. Alveolar retention of Staphylococcus aureus. Conference on the Lung Epithelium in Health and Disease, Federation of American Societies for Experimental Biology. July 28, 2014; Saxtons River, VT. Mini Symposium: Hook JL. Alveolar retention of Staphylococcus aureus. Molecular Underpinnings of Acute Lung Injury, ATS Conference. May 19, 2014; San Diego, CA. Mini Symposium: Hook JL. The frail phenotype in lung transplantation: preliminary results. Scientific and Clinical Innovations in Lung Transplantation, ATS Conference. May 23, 2012; San Francisco, CA. Regional Presentations: Hook JL. Alveolar retention and injury in Staphylococcus aureus lung infection. William A. Briscoe Lung Club, New York City Divisions of Pulmonary and Critical Care Medicine. October 16, 2014; Weill Cornell Medical Center, New York, NY. Local Presentations: Hook JL. Disruption of staphylococcal aggregation protects against lethal lung injury. Research in Progress Seminar, Department of Medicine, CUMC. January 8, 2018; New York, NY. Hook JL. Disruption of staphylococcal aggregation protects against lethal lung injury. Infectious Disease Grand Rounds, Divisions of Infectious Diseases, Departments of Medicine and Pediatrics, CUMC. November 30, 2017; New York, NY. Hook JL. Novel mechanisms of pulmonary edema formation in Staphylococcus aureus lung infection. Research in Progress Seminar, Department of Medicine, CUMC. December 12, 2016; New York, NY. Hook JL. Staphylococcus aureus exploits alveolar niches in acute lung injury. Research Conference, Division of Pulmonary and Critical Care Medicine, CUMC. December 9, 2015; New York, NY. Hook JL. Staphylococcus aureus exploits host properties in lung infection. Multi-Departmental Conference for the Program for Microbial Pathogenesis, CUMC. November 16, 2015; New York, NY. Hook JL. Gap junctions amplify lung injury in Staphylococcus aureus pneumonia. Research in Progress Seminar, Department of Medicine, CUMC. November 9, 2015; New York, NY. 6

7 7 Jaime L. Hook, C.V., p. 7 Hook JL. Mechanisms of lung injury in Staphylococcus aureus pneumonia. Research Conference, Division of Pulmonary and Critical Care Medicine, CUMC. March 25, 2015; New York, NY. Hook JL. Mechanisms of Staphylococcus aureus-induced acute lung injury. Research in Progress Seminar, Department of Medicine, CUMC. January 26, 2015; New York, NY. Hook JL. Alveolar retention and injury in Staphyloccus aureus lung infection. Presentation to the T32 Executive Committee, Division of Pulmonary and Critical Care Medicine, CUMC. July 8, 2014; New York, NY. Hook JL. Alveolar retention and injury in Staphylococcus aureus lung infection. Research Conference, Division of Pulmonary and Critical Care Medicine, CUMC. June 11, 2014; New York, NY. Hook JL. Alveolar epithelial interactions with Staphylococcus aureus. Research Conference, Division of Pulmonary and Critical Care Medicine, CUMC. September 25, 2013; New York, NY. Hook JL. A novel point-of-care oxygen titration study in interstitial lung disease. Grand Rounds, Department of Medicine, CUMC. March 3, 2010; New York, NY. Poster Presentations at Scientific Meetings National and International Meetings: Hook JL and Bhattacharya J. Optical studies of staphylococcal antibiotic resistance mechanisms in lung alveoli. To be presented at: Gordon Research Conference and Seminar, The Biology of Acute Respiratory Infection. March 17-23, 2018; Ventura, CA. Hook JL, Islam MN, Gusarova G, Parker D, Prince A, Bhattacharya J. Novel mechanisms of alveolar injury in Staphylococcus aureus lung infection. Gordon Research Conference and Seminar on the Biology of Acute Respiratory Infection. February 20-26, 2016; Galveston, TX. Hook JL, Islam MN, Gusarova G, Westphalen K, Parker D, Prince A, Bhattacharya J. Alveolar retention of Staphylococcus aureus. Federation of American Societies for Experimental Biology (FASEB) Conference, The Lung Epithelium in Health and Disease. July 27 August 1, 2014; Saxtons River, VT. Hook JL and Chong DH. Influenza A (H1N1) causing severe adult croup and complicated by bacterial tracheitis. American Thoracic Society International Conference. May 16, 2011; Denver, CO. Hook JL, Arcasoy SM, Zemmel D, Bartels MN, Kawut SM, Lederer DJ. Gas exchange and outcome prediction in idiopathic pulmonary fibrosis. American Thoracic Society International Conference. May 15, 2011; Denver, CO. Hook JL, Arcasoy SM, Zemmel D, Bartels MN, Kawut SM, Lederer DJ. A novel point-of-care oxygen titration study in interstitial lung disease. American Thoracic Society International Conference. May 17, 2010; New Orleans, LA. Local Meetings: Hook JL and Bhattacharya J. Localized alveolar-toxin interactions determine lung injury by Staphylococcus aureus. Research Day for Clinical and Postdoctoral Fellows and Scientists, Department of Medicine, CUMC. March 1, 2017; New York, NY. Hook JL, Islam MN, Westphalen K, Parker D, Prince A, Bhattacharya J. Mechanisms of alveolar retention and injury in Staphylococcus aureus lung infection. Research Day for Clinical and Postdoctoral Fellows and Scientists, Department of Medicine, CUMC. March 11, 2015; New York, NY.

8 Jaime L. Hook, C.V., p. 8 Hook JL, Arcasoy SM, Zemmel D, Bartels MN, Kawut SM, Lederer DJ. Gas exchange and outcome prediction in idiopathic pulmonary fibrosis. House Staff Research Day, Department of Medicine, CUMC. March 9, 2011; New York, NY. Hook JL and Smith MA. A longitudinal model for progressive decline leading to frailty in cancer patients. Medical Student Summer Research Fall Forum, UWSMPH. November 17, 2005; Madison, WI. 8