BNF/BNFC Chapter 1 Gastro-intestinal System

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Gavin Shepherd
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1 NF/NF hapter 1 Gastro-intestinal System irections for questions 1 to 10. ach of the questions or incomplete statements in this section is followed by five suggested answers. Select the best answer in each case. 1. Mr. W is a 45 year old man who comes to ask for advice on treating his dyspepsia. Which of the following accompanying symptoms would not require urgent referral for investigation? leeding ysphagia Pain Recurrent Vomiting Weight loss 2. hild is 3 years old suffers from recurrent dyspepsia and the GP recommended a H. Pylori test which came back positive. Which of the following is false? moxicillin and clarithromycin is recommended for initial therapy Omeprazole is the proton pump inhibitor of choice Resistance to metronidazole is more common than amoxicillin Two week therapy with a proton pump inhibitor and one antibacterial can be considered Two-week triple-therapy regimens offer the possibility of higher eradication rates compared to one-week regimens 3. hild is 5 years old and has recently been prescribed dicycloverine for gastro intestinal spasm. His mother comes in to the pharmacy to check to see if the symptoms her son is experiencing is due to a side effect of the medication. Which of the following would not be caused by the medication? onstipation Flushing Pupil constriction Urinary urgency Urinary retention

2 4. mother comes into your pharmacy requesting to buy ranitidine for her son. Over what age would her son need to be to allow you to make this sale? aby is 2 weeks old, is breast fed and weighs 5kg. He has been diagnosed with reflux and has been prescribed Gaviscon Infant. Which of the following is true? dose should be given before every feed maximum of six doses can be given in 24 hours ach dual sachet contains 0.92mmol of sodium One dose should be given with the milk It should not be used if it s given in a room which has a high temperature 6. Mrs. F has come into your pharmacy requesting an indigestion preparation with a low sodium content. Which of the following antacids/alginates do not have a low sodium content? ltacite Plus Suspension lu-ap apsules Gaviscon dvance Suspension Maalox Suspension Mucogel Suspension 7. Mr. has been diagnosed with angle-closure glaucoma. Which of the following treatments should be used with caution by Mr.? lginates ntimuscarinics H2-receptor antagonists Proton pump Inhibitors Simeticone

3 8. Miss M is a 23 year old who has been on stabilised on phenytoin for epilepsy. Which H2-receptor antagonist should not be recommended Miss M? imetidine Famotidine Nizatidine Pirenzepine Ranitidine 9. hild is 4 years old and has just come back from a holiday to Spain. Over the last 24 hours she has been suffering from acute diarrhoea. Which of the following regarding acute diarrhoea is false? ntispasmodics should not be used for primary treatment of acute diarrhoea ntibacterial drugs are usually unnecessary Loperamide can be sold to control the diarrhoea Loperamide works by prolonging the duration of intestinal transit by binding to opioid receptors in the gastro-intestinal tract Oral rehydration therapy can be used for the reversal of electrolyte and fluid depletion 10. Mr. H is a 35 year old man asks for advice about which treatment for constipation would be best for him to request from his GP. Which of the following laxatives would not be suitable for a healthy adult with mild constipation? isacodyl antron ocusate Glycerol Senna 11. hild G is 12 years old and suffers from cystic fibrosis and requires 3600 units of protease, 60,000 units of lipase and 48,000 units of amylase daily. Which of the following would provide the required amount? 2 reon capsules 3 Pancrease HL capsules 6 reon capsules 11g Pancrex granules 12 Pancrex V Forte e/c tablets

4 12. Which of the following statements relating to alsalazide Sodium apsules for the treatment of ulcerative colitis is true?. cannot be prescribed for children under 18 years old. has constipation as a listed side effect. has a maximum maintenance dose for an adult of 3g daily. is safe to use in pregnancy. patients should be counselled on the recognition of blood disorder symptoms 13. Which of the following ointments contain 0.5% cinchocaine and 0.5% hydrocortisone?. Perinal. Proctosedyl. Scheriproct. Ultraproct. Xyloproct irections for questions For each numbered question select from the list above it which is most closely related to it. Within each group of questions each lettered option may be used once, more than once, or not at all Questions 14 to 16 concern the following: luminium Histamine H2 receptor antagonists Magnesium Metoclopramide Sodium icarbonate Select from to above the most appropriate drug for the statements below: 14. has antacid properties and can cause diarrhoea 15. has a constipating effect 16. should be avoided in patients with salt restrictive diets

5 irections for questions For each numbered question select from the list above it which is most closely related to it. Within each group of questions each lettered option may be used once, more than once, or not at all Questions 17 to 19 concern the following:. olestyramine. Infliximab. Mesalazine. Methotrexate. Prednisolone Select from to above the most appropriate treatment for the statements below: 17. is recommended as an option for the treatment of acute exacerbations of severe ulcerative colitis when treatment with ciclosporin is contra-indicated or inappropriate 18. binds bile salts 19. is a corticosteroid

BNF CHAPTER 1: GASTRO-INTESTINAL SYSTEM. 1 April 13

BNF CHAPTER 1: GASTRO-INTESTINAL SYSTEM 1 BNF 1.1 ANTACIDS Mucogel and Peptac are effective antacids and are available over the counter Gaviscon / Gaviscon Advance are available over the counter First