Guideline topic: Sore Throat Review
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1 Guideline topic: Sore Throat Review General comments Search coverage Patient searches Medline, Embase, CINAHL, PsycInfo Guidelines (run on) The guideline search used the patient stem. Guidelines evaluated using AGREE instrument: Systematic reviews: Medline, Embase, CINAHL, Psycinfo and Cochrane Also various websites: Agency for Health Care Research and Quality (AHRQ) ASERNIP-S Canadian Medical Association Centre for Clinical Effectiveness (Australia) Health Technology Assessment NHS Centre for Reviews and Dissemination NHS Quality Improvement Scotland National Institute for Clinical Excellence (NICE) National Electronic Library for Health National Guideline Clearinghouse National Health and Medical Research Council (NHMRC) New Zealand Guidelines Group RCTs KQ4-5 KQ6-8 KQ9-13 Medline, Embase, CINAHL, Psycinfo and Cochrane. 1
2 KQ4-5: 3039 KQ6-8: 1000 KQ9-13: 966 KQ4-5: 87 KQ6-8: 123 KQ9-13: 309 KQ4-5: 51 KQ6-8: 34 KQ9-13: 84 Observational studies Diagnostic studies Economic studies: The main stem was used. No Filter KQ2-3 KQ4: Ibuprofen vs Diclofen KQ4: Ibuprofen and asthma KQ9_10_11 KQ9_10_11: patient satisfaction Medline, Embase, CINAHL, Psycinfo and Cochrane. KQ2-3: 3809 KQ4: Ibuprofen vs Diclofen: 47 KQ4: Ibuprofen and asthma: 421 KQ9_10_11: 58 KQ9_10_11: patient satisfaction: 106 Update Searches: KQ2-3:?? KQ4: Ibuprofen vs Diclofen: 0 KQ4: Ibuprofen and asthma: 19 KQ9_10_11: 2 KQ9_10_11: patient satisfaction: 19 KQ2-3: 51 KQ4: Ibuprofen vs Diclofen: 0 KQ4: Ibuprofen and asthma: 8 KQ9_10_11: 0 KQ9_10_11: patient satisfaction: 5 Pre-sifted hits: 2
3 Search strategies The following are listings of the main Medline strategies used for this guideline. All conventions and symbols are from the Ovid implementation of Medline. Strategies used in other databases were substantially the same, though different terminology may have been used to take account of different thesaurii used in non-medline databases. Search filters were added to identify studies of a particular type (guideline, systematic review, etc.) Listings of the search filters used by SIGN can be found on the SIGN Web site. Patient stem: 1. exp pharyngitis/ or exp tonsillitis/ 2. exp Laryngitis/ 3. pharyngit$.tw. 4. tonsil$.tw. 5. laryngit$.tw. 6. (sore adj3 throat$).tw. 7. exp Tonsillectomy/ 8. or/1-7 KQ (rapid$ adj2 antigen$ adj2 test$).tw. 2. exp Streptococcal Infections/di [Diagnosis] 3. (throat$ adj2 swab$).tw. 4. Streptococ$.tw. 5. (clinic$ adj2 (score$ or scale$)).tw. 6. or/ exp pharyngitis/ or exp tonsillitis/ 8. exp Laryngitis/ 9. pharyngit$.tw. 10. tonsil$.tw. 11. laryngit$.tw. 12. (sore adj3 throat$).tw. 13. exp Tonsillectomy/ 14. or/ and limit 15 to yr=" " 17. (viral$ or virus$ or bacteria$).tw and limit 18 to yr=" " or 19 KQ4: ibuprofen vs diclofenac 1. exp Ibuprofen/ 2. ibuprof$.tw or 2 4. exp Diclofenac/ 5. diclofen$.tw or 5 7. exp pharyngitis/ or exp tonsillitis/ 8. exp Laryngitis/ 9. pharyngit$.tw. 10. tonsil$.tw. 11. laryngit$.tw. 12. (sore adj3 throat$).tw. 13. exp Tonsillectomy/ 14. or/ and 6 and limit 15 to yr=" " KQ4: Ibuprofen and asthma 1. exp Ibuprofen/ 2. ibuprofen$.tw. 3
4 3. 1 or 2 4. exp Asthma/ 5. asthma$.tw. 6. or/ and 6 8. limit 7 to yr=" " KQ exp Analgesics/ 2. exp analgesia/ 3. analgesi$.tw. 4. exp Diclofenac/ 5. diclofenac$.tw. 6. exp Acetaminophen/ 7. (acetaminoph$ or paracetamol$).tw. 8. exp Ibuprofen/ 9. ibuprofen$.tw. 10. exp Aspirin/ 11. aspirin$.tw. 12. exp complementary therapies/ or exp medicine, traditional/ 13. (pain$ adj2 relie$).tw. 14. exp Pain/ 15. (throat$ adj2 spray$).tw. 16. exp Benzydamine/ 17. benzydamine$.tw. 18. exp Administration, Topical/ 19. lozenge$.tw. 20. exp Mouthwashes/ 21. (mouthwas$ or gargle$).tw. 22. exp Steroids/ 23. steroid$.tw. 24. or/1-23 KQ exp Anti-Bacterial Agents/ 2. (antibiotic$ or antibacterial$ or anti-bacterial$).tw. 3. exp Penicillins/ 4. penicillin$.tw. 5. exp Macrolides/ 6. macrolide$.tw. 7. exp Cephalexin/ 8. (cefalexin$ or cephalexin$).tw. 9. exp Amoxicillin/ 10. amoxicillin$.tw. 11. exp Amoxicillin-Potassium Clavulanate Combination/ 12. co-amoxiclav$.tw. 13. exp Antibiotic Prophylaxis/ 14. (antibiotic$ adj2 (prophyl$ or premedic$)).tw. 15. or/1-14 KQ9,10 &11: Lymphoma Post-Tonsillectomy 1. exp Tonsillectomy/ 2. tonsillec$.tw. 3. (remov$ adj3 tonsil$).tw. 4. or/ exp lymphoma/ or exp hodgkin disease/ 6. lymphoma$.tw. 7. hodgkin$.tw. 8. or/ and limit 9 to yr=" " KQ9,10 & 11: Patient Satisfaction 1. exp consumer satisfaction/ or exp patient satisfaction/ 4
5 2. ((parent$ or patient$ or carer$) adj4 satisfac$).tw or 2 4. exp Tonsillectomy/ 5. tonsillectom$.tw. 6. (remov$ adj2 tonsil$).tw. 7. or/ and 7 9. limit 8 to yr=" " KQ9-13: Tonsillectomy 1. exp Tonsillectomy/ 2. tonsillectom$.tw. 3. (remov$ adj2 tonsil$).tw. 4. or/1-3 5
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