Kubios HRV Heart Rate Variability Analysis Software
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1 Kubios HRV Heart Rate Variability Analysis Software Mika Tarvainen, PhD CEO, Kubios Oy MATLAB EXPO Helsinki
2 What is HRV Regulation of heart rate Autonomic nervous system (ANS) To preserve blood pressure homeostasis, ANS regulates Heart rate and cardiac function Vasomotor activity Arterial baroreflex ANS divided into sympathetic and parasympathetic branches
3 HRV time series Continuous regulation of heart rate (HR) Heart rate variability (HRV) Sympathetic activity (GAS) Increases HR and decreases HRV Parasympathetic activity (BRAKE) Decreases HR and increases HRV Respiratory sinus arrhythmia (RSA) High HRV indicates good recovery and high ability to tolerate stress
4 HRV Analysis Methods Time-domain (Mean RR, SDNN, RMSSD etc.) Intensity of HRV Frequency-domain (LF and HF components, LF/HF ratio etc.) Frequency components of HRV (assessment of sympathovagal balance) Nonlinear (Entropy measures etc.) Complexity of HRV Time-varying HRV dynamics
5 Applications of HRV Medical Research Stress and Wellbeing Fitness and Exercise Risk evaluation after MI Evaluation of heart failure Marker of diabetic neuropathy Evaluation of CAD ANS testing Sleep apnea Affective disorders Anesthesia monitoring etc. Occupational stress HRV Biofeedback Resonant frequency Physiotherapy, yoga etc. Fitness assessment maxhr, anaerobic threshold, energy consumption Recovery monitoring Avoiding overtraining Coaching HRV based individualized training prescription
6 Kubios Oy About the company Founded 2016 Software and algorithms development Market leader in HRV analysis software for scientific research and professional use Customers: Researchers, wellbeing therapists, sports/exercise coaches and athletes, personal monitoring etc. Facts and figures Golden Standard HRV software Used in 1000 scientific studies Device independent software Over 40 analysis parameters Used in 120 countries (6/7 continents)
7 Products Kubios HRV Standard (ver. 3.1) For non-commercial personal use Supports most common HR monitors (RR data) Standard HRV analysis Freeware
8 Kubios HRV Premium (ver. 3.1) For research and professional use Supports several HR monitors, ECG and PPG devices Full-featured HRV analysis software 1. Extended data support (ECG and PPG data) 2. Built-in beat detection 3. Automatic correction of missed, extra and misaligned (ectopic) beats 4. ECG derived respiration (EDR) 5. Extended analysis features (spectrogram with fire colormap) 6. Extended reports and exporting options (CSV batch file export)
9 How we use MATLAB How it all started? MATLAB 4.2 and 5 ( ) MSc studies in Medical Physics Used in many courses for practical works and exercises MATLAB 6, 7 and 8 ( ) PhD research in Medical Signal Analysis Development of HRV analysis software started Ver. 1.1 released in Sep 2002
10 Ver. 1.1 (9/2002) GUI Standard HRV Analysis RR data support Windows Ver. 2.0 (10/2008) Nonlinear HRV parameters Support for Polar and Suunto IBI data Windows & Linux Ver. 2.1 (7/2012) QRS detector ECG data support Windows & Linux Ver. 2.2 (5/2014) ECG derived respiration Updates to data support Windows, Linux & Mac MATLAB Compiler Limited functionality (no MCR) MATLAB Compiler Runtime
11 Still relying on MATLAB 1. Optimal for algorithm development and testing Example: Signal baseline fitting N = length(z); lambda = 500; I = speye(n); D2 = spdiags(ones(n-2,1)*[1-2 1],[0:2],N-2,N); z_stat = (I-inv(I+lambda^2*D2 *D2))*z;
12 2. Graphics MATLAB figure uimenu and toolbar 2D & 3D visualisations Highly customizable controls for GUI design Mouse/keyboard interactions MATLAB UI figure (App designer) Interesting, but still some limitations (mouse/keyboard interaction, UImenu support)
13 3. Fast to build applications MATLAB Compiler Matlab code Windows, macos and Linux applications deploytool easy to use, but we need to customize our installers Code signing Agile software development
14 Kubios HRV Premium DEMO Export data from your measurement device
15 Kubios HRV Premium DEMO Export data from your measurement device Suunto HR monitors ( T6 series and Memorybelt Ambit 1, 2 and 3 series Spartan series Export FIT file from Movescout
16 Kubios HRV Premium DEMO Export data from your measurement device Garmin HR monitors ( Forerunner 235, 620, 630, 920XT, 735 XT, 935 Fenix 3, 3HR, and 5; Edge 520, 820, 1000 NOTE: Turn on HRV recording by changing Log HRV setting (Fenix 5 and Forerunner 935) or follow the steps give in Export FIT file from Garmin Connect
17 Kubios HRV Premium DEMO Export data from your measurement device Polar HR monitors ( V800, RS800, RS800CX, CS600, S810 Perform RR recording test and export RR data from Polar Flow web service
18 Kubios HRV Premium DEMO Export data from your measurement device Supported ECG and PPG devices Actiheart and Actiwave Cardio ( Alivecor Kardia ( Biopac ECG and PPG devices ( Bittium Faros ECG ( Empatica E4 ( FirstBeat Bodyguard ( Mindfield MindMaster ( Shimmer ECG and PPG devices ( Zephyr Bioharness ( etc.
19 Kubios HRV Premium DEMO Analysing data in Kubios HRV 1) Opening a recording
20 Kubios HRV Premium DEMO Analysing data in Kubios HRV 1) Opening a recording 2) Check beat detection and correct artefacts if necessary
21 Kubios HRV Premium DEMO Analysing data in Kubios HRV 1) Opening a recording 2) Check beat detection and correct artefacts if necessary 3) Place as many analysis samples as you want (select stationary time periods) 4) All HRV analysis results are computed and visualised immediately
22 Kubios HRV Premium DEMO Analysing data in Kubios HRV 1) Opening a recording 2) Check beat detection and correct artefacts if necessary 3) Place as many analysis samples as you want (select stationary time periods) 4) All HRV analysis results are computed and visualised immediately 5) Apply time-varying analysis
23 Kubios HRV Premium DEMO Analysing data in Kubios HRV 1) Opening a recording 2) Check beat detection and correct artefacts if necessary 3) Place as many analysis samples as you want (select stationary time periods) 4) All HRV analysis results are computed and visualised immediately 5) Apply time-varying analysis 6) Save results PDF, TXT, MAT + SPSS friendly batch file
24 Kubios HRV Premium DEMO Kubios HRV Premium reports 1) Report pages (1 page/sample) Index for parasympathetic nervous system activity Recovery Index for sympathetic nervous system activity Stress
25 Kubios HRV Premium DEMO Kubios HRV Premium reports 1) Report pages (1 page/sample) 2) Report page for time-varying analysis 3) CSV-file 4) MAT-file 5) SPSS friendly batch file
26 Thank you Mika Tarvainen CEO, Kubios Oy Follow us:
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