Song, Xiangzhi; Foley, James W.. "Dyes, compositions and related methods of use." PCT Int. Appl., 107pp., (2010).

Transcription

1 Song, Xiangzhi; Foley, James W.. "Dyes, compositions and related methods of use." PCT Int. Appl., 107pp., (2010). Verma, Sarika; Sallum, Ulysses W.; Athar, Humra; Rosenblum, Lauren; Foley, James W.; Hasan, Tayyaba. "Antimicrobial photodynamic efficacy of side-chain functionalized benzo[a]phenothiazinium dyes." Photochemistry and Photobiology, 85(1), (2009). Song, Xiangzhi; Johnson, Alexis; Foley, James., "7-Azabicyclo[2.2.1]heptane as a unique and effective dialkylamino auxochrome moiety: Demonstration in a fluorescent rhodamine dye." Journal of the American Chemical Society, 130(52), (2008). Song, Xiangzhi; Kassaye, Daniel S.; Foley, James W.. "5,9-Diaminodibenzo[a,j]-phenoxazinium Chloride: A Rediscovered Efficient Long Wavelength Fluorescent Dye." Journal of Fluorescence, 18(2), (2008). Song, Xiangzhi; Foley, James W.. "A new water-soluble near-infrared croconium dye." Dyes and Pigments, 78(1), (2008). Hamblin, Michael R.; Foley, James W.. "Antimicrobial photoinactivation using chalcogen analogs of benzo(a)phenoxazinium dyes." U.S. Pat. Appl. Publ. 32pp, (2008). Blank, David H.; Brown, Benjamin J.; Secord, Michael P.; Foley, James W.. "Methods of marking and related structures and compositions." U.S. Pat. Appl. Publ. 32 pp., (2007). Blank, David H.; Brown, Benjamin J.; Secord, Michael P.; Foley, James W.. "Marking and related structures, packaging articles and compositions." U.S. Pat. Appl. Publ. 15 pp, (2007). O'Riordan, Katie; Akilov, Oleg E.; Chang, Sung K.; Foley, James W.; Hasan, Tayyaba. "Real-time fluorescence monitoring of phenothiazinium photosensitizers and their anti-mycobacterial photodynamic activity against Mycobacterium bovis BCG in invitro and invivo models of localized infection." Photochemical &

2 Photobiological Sciences 6(10), (2007). Akilov, Oleg E.; Kosaka, Sachiko; O'Riordan, Katie; Song, Xiangzhi; Sherwood, Margaret; Flotte, Thomas J.; Foley, James W.; Hasan, Tayyaba. "The Role of Photosensitizer Molecular Charge and Structure on the Efficacy of Photodynamic Therapy against Leishmania Parasites." Chemistry & Biology, 13(8), (2006). Foley, James W.; Song, Xiangzhi; Demidova, Tatiana N.; Jilal, Fatima; Hamblin, Michael R., "Synthesis and Properties of Benzo[a]phenoxazinium Chalcogen Analogues as Novel Broad-Spectrum Antimicrobial Photosensitizers." Journal of Medicinal Chemistry, 49(17), (2006). Nikas, D.C.; Foley, J.W.; Black, P.M., "Fluorescent Imaging in a Glioma Model in Vivo," Lasers Surg Med 29, (2001). Wagner SJ, Skripchenko A, Robinette D, Mallory DA, Hirayama J, Cincotta L, Foley J., "The use of dimethylmethylene blue for virus photoinactivation of red cell suspensions," Dev Biol Stand 102, (2000). Gloster D.; Cincotta, L.; Foley, J.W., "Design, Synthesis, and Photophysical Characterization of Novel Pentacyclic Red Shifted Azine Dyes," J. Heterocycl. Chem 36, (1999). Frimberger, A.E.; Moore, A.S.; Cincotta, L.; Cotter, S.M.; Foley, J.W., "Photodynamic therapy of naturally occuring tumors in animals using a novel benzophenothiazine photosensitizer," Clinical Cancer Research, 4, , (1998). Wagner, S.J.; Skripchenko, A.; Robinette, D.; Foley, J.W.; Cincotta, L., "Factors Affecting Virus Photoinactivation by a Series of Phenothiazine Dyes," Photochemistry and Photobiology, 67, , (1998).

3 Cincotta, L.; Foley, J.W.; Szeto, D.L.; Cincotta, A.H., "Chronophototherapy with EtNBS for the Treatment of Solid Tumors," Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy V, Proceedings SPIE 2392, (1995) 124. Cincotta, L.; Foley, J.W.; MacEachern, T.; Lampros, E.; Cincotta, A.H., "Novel Photodynamic Effects of a Benzophenothiazine on Two Different Murine Sacomas," Cancer Res., 54, 1249, (1994). Gut, I.G.; Redmond, R.W.; Foley, J.; Cincotta, L.; Kochevar, I.E., "A Comparative Investigation of the Photophysical Properties of Substituted Nile Blue A Derivatives," XVII MGH Research Symposium and Poster Session, January 20, Cincotta, A.H.; Lampros, L.; Cincotta, L.; Foley, J.; MacEachern, T., "Novel Benzophenoxazine Analogs Are Efficacious and Unique Photochemotherapeutic Drugs," XVII MGH Research Symposium and Poster Session, January 20, Lin, C.-W.; Shulok, J.R.; Kirley, S.D.; Bachelder, C.M.; Flotte, T.J.; Sherwood, M.E; Cincotta, L.; Foley, J.W., "Photodynamic Destruction of Lysosomes Mediated by Nile Blue Photosensitizers," Photochem. Photobiol., 58, 81-91, (1993). Cincotta, L.; Foley, J.W.; Cincotta, A.H., "Phototoxicity, Redox Behavior, and Pharmacokinetics of Benzophenoxazine Analogues in EMT-6 Murine Sarcoma Cells," Cancer Res., 53, , (1993). Lin, C.-W.; Shulok, J.R.; Kirley, S.D.; Cincotta, L.; Foley, J.W., "Lysosomal Localization and Mechanism of Uptake of Nile Blue Photosensitizers in Tumor Cells," Cancer Res., 51, , (1991). Lin, C.-W.; Shulok, J.R.; Kirley, S.D.; Cincotta, L.; Foley, J.W., "Nile Blue Derivatives as Lysosomotropic Photosensitizers," Optical Methods for Tumor Treatment and Early Diagnosis: Mechanisms and Techniques, Proceedings SPIE 1426, (1991)

4 Foley, J.W.; Cincotta, L., "Evaluation of Nile Blue E Chalcogen Analogs as PDT Agents," Optical Methods for Tumor Treatment and Early Diagnosis: Mechanisms and Techniques, Proceedings SPIE 1426, (1991) Lin, C.-W.; Shulok, J.R.; Wong, Y.-K.; Schanbacher, C.F.; Cincotta, L.; Foley, J.W., "Photosensitization, Uptake, and Retention of Phenoxazine Nile Blue Derivatives in Human Bladder Carcinoma Cells," Cancer Res., 51, , (1991). Lin, C.-W.; Shulok, J.R.; Wong, Y.; Cincotta, L.; Foley, J.W., "Uptake Retention and Phototoxicity of Cationic Phenoxazine Photosensitizers in Tumor Cells in Culture," Proceedings SPIE, 1203, , (1990). Lin, C.-W.; Shulok, J.R.; Wong, Y.K.; Cincotta, L.; Foley, J.W., "Mechanisms of Cellular Uptake and Phototoxicity of New Cationic Phenoxazine Photosensitizers," 3rd Biennial Meeting of the International Photodynamic Association (IPA), July 17-21, 1990, Buffalo, New York. Foley, J.W.; Cincotta, L., "Novel Cationic Photochemotherapeutic Agents: Correlation of Singlet Oxygen Quantum Yields with Molecular Structure of Phenoxazine Derivatives," 3rd Biennial Meeting of the International Photodynamic Association (IPA), July 17-21, 1990, Buffalo, New York. Cincotta, A.H.; Cincotta, L.; Foley, J.W., "Novel Benzophenothiazines in the Photodynamic Therapy of Tumors," 3rd Biennial Meeting of the International Photodynamic Association (IPA), July 17-21, 1990, Buffalo, New York. Foley, J.W.; Cincotta, L., "Photo-inactivation of Cancer Cells," U.S. Patent no. 4,962,197 (1990). Lin, C.-W.; Shulok, J.R.; Wong, Y.; Cincotta, L.; Foley, J.W., "Uptake Retention and Phototoxicity of Cationic Phenoxazine Photosensitizers in Tumor Cells in Culture," Photodynamic Therapy: Mechanisms II, Proceedings SPIE 1203, (1990) Cincotta, A.H.; Cincotta, L.; Foley, J.W., "Novel Benzophenothiazinium Photosensitizers: Preliminary in-vivo

5 Results," Photodynamic Therapy: Mechanisms II, Proceedings SPIE 1203, (1990) Cincotta, L.; Foley, J.W.; Cincotta, A.H., "Novel Phenothiazinium Photosensitizers for Photodynamic Therapy," Advances in Photochemotherapy, Proceedings SPIE 997, (1988) Foley, J.W.; Cincotta, L.; Cincotta, A.H., "Structure and Properties of Novel Benzo[a]phenoxazinium Photochemotherapeutic Agents," Proceedings SPIE, 847, 90-95, (1987). Oseroff, A.R.; Ohuoha, D.; Ara, G.; Kane, S.B.; Foley, J.; Cincotta, L., "The Carcinoma Cell-Selective Phototoxicity of EDKC is Potentiated by Hypoxia and Metronidazole," The 15th Annual Meeting of the American Society for Photobiology, June 21-25, 1987, Bal Harbour, FL, 101S. Ohuoha, D.C.; Cincotta, L.; Foley, J.; Oseroff, A.R., "Enhancement of EDKC Phototoxicity by Cellular Glutathione Depleting Agents Buthionine Sulfoxine (BSO) and Diethyl Maleate (DEM)," Clayton Foundation Conference on Photodynamic Therapy, February 15-19, 1987, Los Angeles, CA, 123. Oseroff, A.R.; Ohuoha, D.; Ara, G.; Foley, J.; Cincotta, L., "Selective Carcinoma Cell Photolysis (SCCP). The Preferential Light-Induced Killing of Carcinoma Cells Due to Mitochondrial Accumulation of Cationic Dyes is Potentiated by 2-Deoxy-d-glucose (2-DG) and Hyperthermia," Clayton Foundation Conference on Photodynamic Therapy, February 15-19, 1987, Los Angeles, CA, 109. Cincotta, L.; Foley, J.W.; Cincotta, A.H., "Novel Red-Absorbing Benzophenoxonium and Benzophenothiazonium Photosensitizers," Clayton Foundation Conference on Photodynamic Therapy, February 15-19, 1987, Los Angeles, CA, 122. Ara, G.; Cincotta, L.; Foley, J.; Hruza, G.; Anderson, R.R., "Phototoxicity of Melanoma Cells by High-Intensity Ruby Laser Radiation," Clayton Foundation Conference on Photodynamic Therapy, February 15-19, 1987, Los Angeles, CA, 51.

6 Oseroff, A.; Foley, J.; Cincotta, L.; Parrish, J.A., "Light-Induced Killing of Carcinoma Cells," U.S. Patent no. 4,651,739 (1987). Oseroff, A.R.; Ara, G.; Ohuoha, D.; Aprille, J.; Bommer, J.C.; Yarmush, M.L.; Foley, J.; Cincotta, L., "Strategies for Selective Cancer Photochemotherapy: Antibody-Targeted and Selective Carcinoma Cell Photolysis," Photochem. Photobiol., 46 (1), 83-96, (1987). Cincotta, L.; Foley, J.W.; Cincotta, A.H., "Novel Red Absorbing Benzo[a]phenoxazinium and Benzo[a]phenothiazinium Photosensitizers: in-vitro Evaluation," Photochem. Photobiol., 46, , (1987). Valdes-Aguilera, O.; Cincotta, L.; Foley, J.; Kochevar, I.E., "Photobleaching of a Cyanine Dye in Solution and in Membranes," Photochem. Photobiol., 45, , (1987). Oseroff, A.R.; Ohuoha, D.; Ara, G.; McAuliffe, D.; Foley, J.; Cincotta, L., "Intramitochondrial Dyes Allow Selective in vitro Photolysis of Carcinoma Cells," Proc. Natl. Acad. Sci. USA, 83, , (1986). Ara, G.; Aprille, J.; Foley, J.; Cincotta, L.; Oseroff, A.R., "A Kryptocyanine Dye Causes Photosensitized, Site- Specific Inhibition of Mitochondrial Electron Transport, and Alters ATP Levels and Cell Cycle Distributions," 14th Annual Meeting of the American Society for Photobiology, June 1986, Los Angeles, CA, 49S. Valdes-Aguilera, O.; Cincotta, L.; Foley, J.; Kochevar, I.E., "Active Oxygen Species in the Photolysis of 1,1'-(2- Ethyl-1,3-dioxolane)kryptocyanine (EDKC)," 14th Annual Meeting of the American Society for Photobiology, June 1986, Los Angeles, CA, 48S. Oseroff, A.R.; Ohuoha, D.; McAuliffe, D.; Ara, G.; Shea, C.; Foley, J.; Cincotta, L., "Selective Mitochondrial Photolysis (SMPL): A New Mitochondrial Specific Photochemotherapy," Photochem. Photobiol., 41 Suppl., (1985). Valdes-Aguilera, O.; Kochevar, I.E.; Foley, J.; Cincotta, L., "Spectral Characterization of the Mitochondrial Dye

7 1,1 -(2-Ethyl-1,3-dioxolane)kryptocyanine (EDKC)," Photochem. Photobiol., 41 Suppl., (1985). Hasan, T.; Yarmush, M.; Foley, J.; Cincotta, L.; Oseroff, A., "Selective Targeting of Laser Damage with Exogenous Chromophores Coupled to Monoclonal Antibodies," 189th National Meeting of the American Chemical Society, 28 April-3 May 1985, Miami Beach, FL.