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1 (2 ) * : :... (TG). (). -.(r= 0/95) :. TG. NCEP-ATP-III. :. () : : ronakn2000@yahoo.com :
2 ... : 198.[4] C.[4]. NCEP.[4] (NCEP-ATP-III) III ) (. ().[1 2] NCEP-) (ATP III..[1] = Total.[3] ( ) Cholesterol-(HDL+TG/5) HDL.[4].[5] (TG 400).[4].[6-10] NCEP-ATPIII (HRT) III
3 199 (2 ) NCEP. ( ATP-III). 2 (%46/6) /90 123/0318/54 mmhg.69/8511/51 mmhg 17/65 6/58. 21/4114/05 (-C. 1/70/8 ) NCEP. 3 NCEP mg/dl /25 (C-) 15/87 (D-) TG. 5 Post Hoc D-.(P< C- 0/0001) Analysis 55 ) ( 65. ( 10 ) (TC) (TG) (HDL). () NCEP-ATPIII. t-test. ANOVA. -. SPSS 16
4 ... : 200 D- C-. r=0/95 P< 2 0/0001).(D- =(%95 C-) /15. D- C-. C- 40/ / /76 (P< /0001) 0/38 (P< D- 0/0001) 0/19 53/37 113/99 29/31.. (Bland-Altman Difference Plat) /07 113/39 D- C- X (Bias) Y. NCEP -4/25 15/87 ( ) -35/34-4/88.(1) 25/38. 6 (n =352) / / / / / / / / /5 44 0/56 2
5 201 (2 ) NCEP -2 (n =352) 20/ / / /3 1 10/ / /6 164 (BP 140/90 ) 77/ (HDL< 40 mg/dl) HDL 2/84 10 ( 65 > 55> ) 43/ ( 55 45) NCEP (-C ) -3 (n=352) NCEP 25/ / / (n=339) 46/54 200/ /33 167/ /65 49/ HDL 41/05 117/ ,5 30/64 112/ D- C- -5 (n=339) D- C- (mg/dl) TG -9/27 12/72 * --6/94 14/25 * -0/62 15/31 * 8/47 17/ < P< 0/05 * ANOVA 339.
6 ... : 202 NCEP -6 (n=339) < 130 N (%) N (%) N (%) (%14/74) 50 (%1/17) 4 (%6/48) 22 (%7/07)24 (%16/33) 52 (%3/24) 11 (%7/66) 26 (%4/42) 15 (%26/54) 90 (%3/24) 11 (%10/02) 34 (%13/27) 45 (%28/31) 96 (%6/78) 23 (%10/91) 37 (%10/61) (%22/12) 75 (%0/88) 3 (%8/25) 28 (%12/97) 44 (%21/53) 73 (%1/76) 6 (%9/73) 33 (%10/02) (%63/42) 215 (%5/30)18 (%24/77) 84 (%33/33) 113 (%65/19) 221 (%11/79) 40 (%28/31) 96 (%25/07) (n=339)
7 203 (2 ) D- C- -2.(n=339) D- C-. 0/95. 0/96.[11] (Women Health Study)..[12] 0/ (r=0/95)
8 ... : 204 :. V V ) ( V LP(a).[13]. IDL Li. LP(a) LP(a) (> 600 mg/l mg/l 300 mg/l) ).(%21/4 %8/5 %4/1 LP(a).[16] 300 LP(a) LP(a). %4 LP(a) Mora.. D- C-. C- D [13-15]. C- D- De Cordova.[13] 0/97 0/89 mg/dl ( 4/88 ) Mora.[12] 7 2 De Cordova 300 ) ( Nauk.[13].[14] Can. %14. ( ).[4 15]
9 205 (2 ) [14] mg/dl 400 Mora.[13] mg/dl 400 : -. D- (r=0/38) (r=0/19) C-....[14] mg/dl 130..[17].
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11 207 (2 ) Can M, Acikgoz S, Mungan G, et al. Is direct method of low density lipoprotein cholesterol measurement appropriate for targeting lipid lowering therapy? Int J Cardiol Jan 2010; 142(1): Mora S, Rifai N, Buring JE, Ridker PM. Comparison of Cholesterol Concentrations by Friedewald Calculation and Direct Measurement in Relation to Cardiovascular Events in Women. Clin Chemistry 2009; 55(5): De Cordova CMM, Schneider CR, Juttel ID, de Cordova MM. Comparison of -Cholesterol Direct Measurement with the Estimate Using the Friedewald Formula in a Sample of 10,664 Patients. Arquivos Brasileiros de Cardiologia 2004; 83: Nauck M, Rifai N. Analytical performance and clinical efficacy of three routine procedures for cholesterol measurement compared with the ultracentrifugation-dextran sulfate-mg (2+) method. Clin Chim Acta 2000; 294: Yu HH, Ginsbrug GS, Harris N et al. Evaluation and clinical application of a direct low density lipoprotein cholesterol assay in normolipemic and hyperlipidemic adults. Am J Cardiol 1997; 80: Li KM, Wilcken DE, Dudman NP. Effect of serum lipoprotein (a) on estimation of lowdensity lipoprotein cholesterol by the Friedewald formula. Clin Chem 1994; 40: Scharnagl H, Nauck M, Wieland H, Marz W. The Friedewald formula underestimates cholesterol at low concentrations. Clin Chem Lab Med 2001; 39:
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