Donating your baby s cord to a public cord blood bank can save lives globally.

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2 Donating your baby s cord to a public cord blood bank can save lives globally. You can play an important role in saving lives by donating the blood contained in your baby s umbilical cord to LifeCord, a nonprofit, public cord blood bank. Donating blood is free and will not affect you, the baby or the birthing process. To-do list for umbilical cord donor moms Let your obstetrician or midwife know of your desire to donate your cord blood. If possible, pre-register with LifeCord staff. Make sure that all of your registration forms have been filled out completely. o Maternal Demographic Information Form o Family Medical History Questionnaire o Maternal Risk Questionnaire The day of delivery remind your delivery team that you want to donate your cord blood. They will obtain your consent to collect the cord blood and collect a small blood sample from you for disease testing. Hospital partners LifeCord currently collects umbilical cord blood at 12 hospitals in Florida, Georgia and Alabama. Baptist Medical Center East Montgomery, Alabama Baptist Medical Center South Montgomery, Alabama Brookwood Medical Center Birmingham, Alabama East Alabama Medical Center Opelika, Alabama Jackson Hospital Montgomery, Alabama Northeast Alabama Regional Medical Center Anniston, Alabama North Florida Regional Medical Center Gainesville, Florida UF Health Shands Hospital Gainesville, Florida Jackson Memorial Hospital Miami, Florida Gwinnett Medical Center Lawrenceville, Georgia Northeast Georgia Medical Center Gainesville, Georgia Piedmont Henry Hospital Stockbridge, Georgia We can t do it without you.

3 About cord blood donation What is cord blood? Cord blood is the blood remaining in the umbilical cord and placenta after a baby is born. Cord blood is rich with blood-forming cells. How is cord blood used? Each year, thousands of people are diagnosed with cancer and other life-threatening diseases, such as leukemia or sickle cell disease, that can be treated with a cord blood transplant. Cord blood transplants replace diseased blood-forming cells with healthy cells. The treatment process is similar to a bone marrow transplant, except that cord blood is used instead of marrow. Like marrow, cord blood is rich in stem cells which generate new blood cells to resist disease. A cord blood unit does not have to match a patient s tissue type as closely as donated marrow does. This means more patients are able to receive transplants. Who needs a cord blood transplant? Patients in need of a transplant quickly. Cord blood units are stored and ready to use immediately. Patients who have a hard time finding a matched bone marrow donor. Cord blood does not have to match a patient s tissue type as closely as donated bone marrow does. Patients from racially or ethnically diverse communities who often have uncommon tissue types. Because cord blood does not have to match the patient as closely as bone marrow does, it may offer more people from diverse racial and ethnic communities a chance for a cure. What happens to cord blood if it is not donated? The umbilical cord, placenta and lifesaving blood they contain are usually discarded after birth. Is there any cost for donation? There is no cost for donating cord blood to a public cord blood bank such as LifeCord. LifeCord incurs the cost of collecting, testing, processing and storing the cord blood. How is cord blood donated? Donating cord blood to a public cord blood bank involves talking with your doctor or midwife about your decision to donate. If possible, pre-register with LifeCord staff. Upon arriving at the hospital, remind the labor and delivery team that you are donating your umbilical cord blood. The hospital staff will discuss the process with you and obtain your consent. They will collect a small amount of blood from you so that disease testing can be performed. After the delivery of your baby, the umbilical cord and placenta are no longer needed. The blood remaining in the umbilical cord and placenta will be collected and tested. The collection procedure is painless and does not interfere with the normal birthing process. By donating umbilical cord blood, you choose to potentially help someone in need of a lifesaving transplant. Ethnic diversity Not all patients are able to find a match on the National Marrow Donor Program registry. Patients from racially or ethnically diverse backgrounds often have uncommon tissue types. A patient s likelihood of finding a match on the Be The Match Registry is estimated to range from 66 percent to 97 percent, depending on race or ethnicity. African-American or black patients have an estimated 66 percent likelihood of finding a match on the registry.* What this means is that African-Americans are least likely to find a match. By increasing the number of minority cord blood units on the registry, minority patients will be more likely to find a match. *bethematch.org

4 Why should you donate your cord blood to a public bank? One of the most common misconceptions about private cord blood banking is that a child s own cord blood can be transplanted if he develops a disease later in life. In many cases, diseases such as leukemia are genetic, so the cord blood that is banked at birth already carries the same disease. For this reason, the routine storage of umbilical cord blood as biological insurance against future disease is not recommended by the American Academy of Pediatrics. Most people who need transplants use cord blood donated by a sibling or a public cord blood bank. Cord blood recipients have about a 25 percent chance of matching a sibling and a 75 percent chance of finding a match from a public bank. Only a small percentage of babies (estimated at between 1 in 1,000 to 1 in 200,000) ever use their own, privately banked cord blood. By choosing to donate your baby s cord blood to a public bank like LifeCord, you are doing your part to help ensure that more people in need of lifesaving cord blood transplants are able to find a match. The cost of private cord blood banks Private cord blood banks charge mothers up front, including registration, harvesting, processing and storage fees. LifeCord vs. private cord blood banks LifeCord Available for transplant to anyone globally FREE FREE Private Cord Blood Bank Availability May be available for you and your family Cost for Initial Storage Initial storage fee: approximately $2,000 Yearly storage fee: approximately $150 Additional Costs If the cord blood unit is requested for transplant for someone other than the donor, you incur the cost of transportation, HLA typing, disease and CD34 testing LifeCord has provided cord blood units for transplants in more than 29 states and 17 countries. Washington Oregon California Colorado Canada Massachusetts Minnesota Wisconsin New York Michigan Utah New Jersey Illinois Maryland Indiana Pennsylvania Ohio Virginia Kentucky S. Carolina N. Carolina Oklahoma Texas Tennessee Georgia Kansas Alabama Louisiana Florida Scotland Denmark England Germany Ireland Austria Belgium France Netherlands Switzerland Spain Italy Israel Brazil Australia As of March 2017 Argentina

5 Archie For 9 1/2 years, he waited for a lifesaving transplant and lost his battle with cancer on December 10, Devon She received a lifesaving transplant at the age of 15 and was able to fulfill her dream of attending law school. The difference between them? One cord blood donation.

6 Diseases treatable by stem cell transplantation The following diseases may be treated by a transplant using hematopoietic stem cells obtained from umbilical cord blood, peripheral blood or bone marrow under appropriately approved research protocols.* *Information obtained from Be The Match Acute Lymphoblastic Leukemia (ALL) Acute Myelogenous Leukemia (AML) Chronic Myelogenous Leukemia (CML) Histiocytic Disorders Familial Erythrophagocytic Histiocyosis Histiocytosis-X Hemophagocytosis Other Histiocytic Disorders Hodgkin s Lymphoma Inherited Erythrocyte Abnormality Beta Thalassemia Major Fanconi Anemia Pure Red Cell Aplasia Sickle Cell Disease Inherited Immune System Disorders Ataxia-Telangiectasia Combined Immunodeficiency Kostmann Syndrome Leukocyte Adhesion Deficiency Chediak-Higashi Syndrome Ommenn s Syndrome Severe Combined Immunodeficiency (SCID) SCID with Adenosine Deaminase deficiency Absence of T & B Cells SCID Absence of T Cells, Normal B Cell SCID Other SCID Wiskott-Aldrich Syndrome X-Linked Lymphoproliferative Disorder Other Immune System Disorders Inherited Metabolism Disorders Adrenoleukodystrophy Sly Syndrome, Beta-Glucuronidase Deficiency Gaucher s Disease Hunter s Syndrome Hurler s Syndrome Krabbe Disease Maroteaux-Lamy Syndrome Metachromatic Leukodystrophy Neiman-Pick Disease Other Mucopolysaccharidosis Osteopetrosis Sanfilippo Syndrome Wolman Disease Other Inherited Metabolic Disorders Inherited Platelet Abnormalities Amegakaryocytosis/Congenital Thrombocytopenia Myelodysplastic Disorder Syndromes Acute Myelofibrosis Chronic Myelomonocytic Leukemia (CMML) Essential Thrombocythemia Idiopathic Sideroblastic Anemia Myelodysplastic Disorder Myelofibrosis /Myeloid Metaplasia Paroxysmal Nocturnal Hemoglobinuria Polycythemia Vera Refractory Anemia Refractory Anemia with Excess Blast Refractory Anemia with Excess Blast with Transformation Unknown Myelodysplastic Disorder Other Myelodysplastic Disorder Non-Hodgkin s Lymphoma Other Leukemia Acute Biphenotypic Leukemia Acute Undifferentiated Leukemia Chronic Lymphocytic Leukemia Juvenile Chronic Myelogenous Leukemia Prolymphocytic Leukemia Other Leukemia Other Malignancy Breast Cancer Renal Cell Carcinoma Other Non- Malignant Diseases Plasma Cell Disorders Multiple Myeloma Plasma Cell Leukemia Unknown Plasma Cell Disorders Waldenstrom s Macroglobulinemia Other Plasma Cell Disorder Severe Aplastic Anemia

7 About LifeSouth Who we are Founded in 1974, LifeSouth is a 501(c)(3) nonprofit community blood supplier for hospitals in Alabama, Florida and Georgia. LifeSouth employs more than 800 people throughout our footprint. With more than 1,000 blood drives a month, 27 donor centers and 45 bloodmobiles, LifeSouth supplies more than 278,000 blood components to more than 100 community hospitals annually. Our mission To provide a safe blood supply that meets or exceeds the needs in each community we serve, and to provide a variety of services in support of ongoing and emerging blood and transfusion-related activities. LifeSouth received FDA licensure for cord blood manufacturing in June 2013, becoming the fifth cord blood bank nationwide that is licensed by the FDA. LifeCord LifeCord is a program of LifeSouth Community Blood Centers. Established in 1998, it was the first public cord blood bank in the Southeast. LifeCord collects umbilical cord blood from newborns at hospitals in Florida, Georgia and Alabama. So far, stem cells from LifeCord collections have been used for transplants in more than 29 states and 17 countries (see map). The LifeCord staff has demonstrated a passion for this, and they are tirelessly working to provide a needed service. Receiving the FDA license indicates that we are meeting the highest and most stringent standards for providing high quality products to the patients we serve. This is an example of how the cooperative effort of our partner hospitals and LifeSouth can work together to promote health. - LifeCord Medical Director Dr. John Wingard

8 LifeCord is a public nonprofit cord blood bank licensed by the FDA. All banked cords are registered with the Be The Match Registry

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