Mindful Reflections On The Management. of Venous Ulceration. Presenter name. Title Date

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1 C Scott McEnroe, MD, FACS Medical Director Vein Center of Virginia Sentara Vascular Specialists April 25 th, 2014 Mindful Reflections On The Management of Venous Ulceration

2 Approximately 97 % of all statistics are made up. The Book of Useless Information By Noel Botham and the Useless Information Society

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5 What cannot be cured by medications is cured by the knife, what cannot be cured by the knife is cured by the searing iron, whatever this cannot cure must be considered incurable. 460 BC Hippocrates Prescribed compression following multiple punctures without excision of varicose veins.

6 Ulcers on the leg form a very extensive and important class of diseases... The treatment of such cases is generally looked upon as an inferior branch of practice; an unpleasant and inglorious task where much labour must be bestowed, and little honor gained. The Inquirer (1805). What are the comparative advantages of the different modes proposed for the treatment of ulcerated legs? Edinburgh Medical and Surgical Journal, I,

7 Compression dressings and a blind eye

8 Significance of Venous Ulceration Most common cause of LE ulceration Affects % of world population Highest prevalence in year olds High disability rate: 4.6 million lost work days/year High cost of care: 1-3% worldwide healthcare budget

9 A Few Good and Noble Physicians Debridment, STSG, Compression Dressings Great Saphenous Stripping Varicose Vein Excision Subfascial Ligation Perforating Veins-Linton Presenter Procedure name

10 Compression dressings and a blind eye

11 A Few Good and Noble Physicians Deep Venous Reconstruction valvuloplasty, venocuff popliteal vein valve transplant sapheno-femoral/popliteal venous bypass

12 Compression dressings and a blind eye

13 Did these interventions make a difference??? Most healed Many recurred The rest never came back!!!

14 Just because it is broke doesn t mean it needs to be fixed! Where did we go wrong? Assumption that visible venous abnormalities were pathologic cause of ulceration Blind intervention Surgical trauma lymphatic disruption Poor wound healing infection

15 John Gay 1855 The frequent coincidence of indolent ulcers and varicose veins gave rise to the belief that such ulcers are directly due to the disease in the veins; and to the practical inference that it is only necessary to obliterate the veins and the ulcers will heal. The corollary has not, however, been fully borne out by experience. Lancet 1868 When a vein was ligated for the cure of a leg ulcer...with what gratification the cicatrisation of the ulcer is hailed in almost every case. Presenter But if these name cases were followed up, it was generally found that the ulcer and varicose veins have both reappeared. Are we satisfied that even the temporary benefit was due to the ligature? I confess, I am much more disposed to attribute it to the rest and other means that were simultaneously employed.

16 Compression dressings and a blind eye

17 Prescription for Optimal, Cost Effective Management of Venous Ulceration

18 Was this all for nothing... Reduce surgical trauma Diagnostic evaluation Define pathophysiology Develop algorithms for management

19 1990 s Minimally Invasive Technology Boom GSV stripping devices Endoscopic interruption of perforating veins Powered phlebectomy Advancements in Duplex Imaging Technology Some understanding of pathophysiology Limited clinical data

20 Ulcer healing and recurrence rates unchanged

21 Was this all for nothing...too?...no and Yes Ambulatory surgery Fewer wound related complications Saphenous stripper devices atraumatic SEPS, TRIVEX...UGH! Long learning curve Traumatic Prolonged recovery

22 Was this all for nothing...too? New approach, New devices...new LAYER OF MISERY Insurance preauthorization Outpatient/office based wound care Expensive Time consuming Eventual referral to Wound Care Center Surgeons dumping ground More clueless than we were

23 Sinking Under The Weight Of Our Own Technology No evidence to suggest that saphenous or Broken Hippocratic Oath perforator vein surgery improved healing rates Cool new tools that worked, but didn t help or decreased recurrence. Increased cost of care Most ulcers healed with compression and good wound care regardless of surgical Delegated wound care to WCC intervention. Recurrence, not healing, was the real issue.

24 Endovenous Ablation Game Changer of the Century Radiofrequency- VNUS (Closure) 1999 Laser- ELVS (AngioDynamics) 2002

25 Not just a better mousetrap GSV, SSV, accessory branches, AND ICPV s Improved understanding of venous insufficiency Correlation of clinical/duplex findings on every case Detailed pre-op duplex Duplex directed treatment Post treatment duplex Same sequence for each recurrence Simple varices, symptomatic varices, venous ulceration

26 I Have Seen A lot Of Recurrences... And Am Glad I Did! WHAT? Second correlation of clinical/duplex findings Etiology of recurrences Incompetent, residual distal GSV Incompetent accessory or tributary branch of GSV ICPV s

27 Now We Are Getting Somewhere Percutaneous Ablation of Perforating Veins (PAPS) Laser Rapid clinical response ulcer pain Skin stasis changes Ulcer healing Foam Sclerotherapy Same clinical response Cheaper Technically simple Ablate other sources of recurrence

28 Foam Sclerotherapy...It gets even better! Recurrent Ulcer Duplex Demonstrates Nothing NOW WHAT!

29 Obsession With ICPV s Definition Of Insanity Subfascial Ligation

30 Venous Ulceration Local Manifestation of Systemic Problem Terminal Interruption of Reflux Source (TIRS) END ORGAN

31 Pan Subdermal Sclerosis PASS PAPS & TIRS=PASS END ORGAN

32 150 Years Later... Pan Subdermal Sclerosis PASS Same rapid clinical response seen with PAPS ulcer pain Skin stasis changes Ulcer healing Repeat PRN PAPS TIRS

33 Current Therapeutic Approach Treat all axial reflux RF, laser Foam (Varithena) Cyanoacrylate (Sapheon) Pan Subdermal Sclerosis PASS Inelastic compression Unna s Boot Circ-Aid Lifelong elastic compression Annual venous duplex

34 SUPERGLUE The Future As I See It Less Is Better SOAP VELCRO

35 Q: What s the difference between a surgeon and a puppy? A: If you put a puppy in a room by itself for an hour, it will probably stop whining.

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