Molecular Physiology, Haematology, Animal Physiology and Biochemistry and Genomics

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1 BISNU PRASAD DASH Reader: (since ) M.Sc: 1983 (Utkal University) M.Phil: 1986 (Sambalpur University) Ph.D (Sambalpur University) Mobile: , Ph. No.: (Res.) bishnu_rmrc@yahoo.co.in and bisnu_fmu@yahoo.co.in Field of Specialization: Molecular Physiology, Haematology, Animal Physiology and Biochemistry and Genomics Research Experience: Sixteen years at RMRC, ICMR, Bhubaneswar and >6 years in F.M.University, Balasore. Research Guidance: Ph. D. 5, M.Phil. 1 and M.Tech. 4 Teaching Experience: 3 years (UG) and > 6 years (PG) Publications: 31 (International 5, National 31) Conferences attended: International 6, National 27. Referee: Annals of Haematology and African Journal of Environmental Science and technology (International Journals) PRINCIPAL INVESTIGATOR IN RESEARCH PROJECTS 1. Principal Investigator in the ongoing ( ) research project entitled Molecular analysis of haemoglobin mutations among some selected tribes of three Northern districts of Orissa funded (Rs.8.02 Lakh) by the Director Biotechnology, Department of Science and Technology, Govt. of Orissa. 2. Principal Investigator in the ongoing ( ) Major research project entitled Characterization and assessment of potential target compound(s) having anti-sickling activity from some plant extracts of Orissa funded (10.62 Lakh) by the University Grants Commission (UGC), New Delhi.

2 TRAINING OBTAINED: 1. Molecular Biotechnology and Bioinformatics from 16 th -20 th May 2011 at International Institute of Information Technology (I 2 IT), Pune. 2. Pre-implantation Genetic Diagnosis (PGD) from 19 th -30 th May 2008 at National Institute of Reproductive Health (ICMR), Parel, Mumbai. 3. National Training cum Workshop on Bioinformatics, 24 th and 25 th March 2007, F. M. University, Balasore. 4. Workshop cum training on Opto-Analytical Instruments, 26 th to 31 st March 2007, F. M. University, Balasore. 5. Advanced Molecular Haematological Techniques for identification of Haemoglobinopathies and allied disorders from 2 nd -16 th May 2001, at Institute of Immunuhaematology, ICMR, Mumbai. 6. Haemophilia and Coagulation disorders organized by HFI, from 4 th -13 th July 2000, at Institute of Immunuhaematology, ICMR, Mumbai. 7. DNA isolation, Southern blotting, Dot blotting, PCR, and DNA sequencing etc. during the Indo- Japan International Workshop on DNA diagnostics held from 15 th -22 nd January 1994, at SGPGIMS, Lucknow. PUBLICATIONS International: 1. Basu, S, Dash, B.P., Patel, D.K., Chakravarty, S., Chakravarty, A., Banerjee, D., Chakrabarti, A. (2011) F-cell levels are altered with erythrocyte density in sickle cell disease. Blood Cells, Molecules, and Diseases. 47: I.F: 2.716, ISSN: Dash, B.P. and Kar, B.C. (2006) Sickle cell Haemoglobin Dpunjab disease in Orissa state, India. Haema 9: ISSN: Ranjit, M.R., Das, A., Das, B.P., Das, B.N., Dash, B.P. and Chhotray, G.P. (2005).Distribution of P. falciparum genotypes in clinically mild and severe malaria cases in Orissa, India. Trans. Royal Soc. Trop. Med. & Hyg. 99: I.F.:2.832, ISSN:

3 4. Chhotray, G P., Dash, B.P., and Ranjit M.R. (2004) Spectrum of hemoglobinopathies in Orissa, India. Hemoglobin. 28(2): I.F: 1.414, ISSN: Chhotray, G.P., Dash, B.P., Ranjit M.R, Cohla, R and Mohanty D. (2003) Haemoglobin E beta thalassaemia- An experience in eastern Indian state of Orissa. Acta haematologica. 109; I.F: 1.316, ISSN: National: 1. Dash, B.P. (2009) Sickle Cell Disorders: Biotechnological approach for prevention and cure. In: Biotechnological Applications, I. K. International Publishing House Pvt. Ltd, New Delhi, pp Dash, B.P. (2008) Prenatal diagnosis in prevention and control of haemoglobino-pathies in Orissa. Anvesa.3 (1): ISSN: X. 3. Dash B.P., Das A., and Misra A.N. (2008) Morphological studies of Indian Horseshoe crab (Tachypleus gigas) from Chandipur beach of east India. Anvesa.3 (1): ISSN: X. 4. Dash, B.P. (2006) Sickle cell Disorders in Orissa. Man in Society, 16: Dash, B.P. (2005) Biotechnological Application to Common Health Problems in Orissa. Anvesa, 1(1): ISSN: X. 6. Balgir, R S., Dash, B P. and Murmu B. (2004) Blood groups, hemoglobinopathy and G6PD deficiency investigations among fifteen major scheduled tribes of Orissa, India. The Anthropologist. 6(1): ISSN: Balgir, R.S., Kerketta, A.S. Murmu, B and Dash, B.P. (2002) Clinical assessment of health and nutritional status of Gond children in Kalahandi district of Orissa. Indian J Nutri Dietet. 39: ISSN: Dash, B.P, Mittra A and Kar B.C (2001) Time dependent glucose consumption in sickle haemoglobin containing red blood cells. North Orissa University Research Journal. 1; Dash, B.P. and Kar, B.C. (2000) Priapism is rare in sickle cell disease in India. JAPI. 48(2): 255. ISSN: Dash, B.P., Mittra, A. and Kar, B.C. (1999) Osmotic fragility of normal and sickle haemoglobin containing red blood cells. Indian J Physiol Pharmacol. 43(2): Balgir, R.S., Dash, B.P. and Murmu, B. (1999) Hereditary haemolytic disorders among the Ashram school tribal children in Mayurbhanja district of Orissa. JAPI. 47(10) :

4 12. Balgir, R.S., Murmu, B. and Dash, B.P. (1999) Physical growth, health and nutritional status of the Ashram school tribal children in Northern Orissa. Indian J Nutri Dietet. 36: Dash, B.P. and Das, R.K. (1998) Age, Sex and seasonal variations of sickle cell disorder cases in Orissa. J Human Eco. 9(3): Majumder, P.P., Roy, B., Balgir, R.S., Dash, B.P., (1998) Polymorphism in the Beta-globin gene cluster in some ethnic population of India and their implications on disease. In: Molecular Intervention in Disease. Ranbaxy Science Foundation, New Delhi. pp Balgir, R.S., Murmu, B. and Dash, B.P. (1998) Health and nutritional status of Ashram school childrren in two district of Orissa. Ind J Nutr Dietet. 33: Balgir, R.S., Dash, B.P. and Murmu, B. (1997) Haemoglobinopathy, G6PD deficiency and blood groups among the tribals of Sundergarh district in Orissa. Indian J Haematol Blood Transf. 15(3): Tripathy, D., Dash, B.P., Mohapatra, B.N. and Kar, B.C. (1997) Cholelithiasis in sickle cell disease in India, JAPI. 45: Balgir, R.S., Dash, B.P. and Das,R.K. (1997) Foetal outcome and childhood mortality in offspring of mothers with sickle cell trait and disease. Indian J Paediatric, 64: Dash, B.P. and Kar, B.C. (1996) Haemoglobin SD disease in a Muslim boy. Indian J Haematol Blood Transf, 14 : Roy, B., Dey, B., Balgir, R.S., Dash, B.P., Chakraborty, M., Bhattacharya, S.K., Banerjee, S., Roy, M. and Majumder, P.P. (1996) Identification of sickle cell homozygotes using haematological parameters. J Indian Anthrop Soc, 31: Dash, B.P. and Kar, B.C. (1995) Possible genetic link of high HbF in Indian Sickle Cell Disease (SS) patients. Indian J Hematol Blood Transf, 13: Kar, B.C., Devi,S., Pattnaik, G., Dash, B.P. and Das, R.K.(1994) HbF levels do not determining the clinical course of 'SS' disease. Indian J Haematol Blood Transf, 12: Dash, B.P., Das, R.K., Pattanaik, G. and Kar,B.C.(1993) Foetal haemoglobin in normal, sickle cell trait and sickle cell disease patients in Western Orissa, India. Ind J Hematol Blood Transf, 11: Kar, B.C. and Dash, B.P. (1993) Sickle Cell Disease with Diabetes Mellitus. Ind Practitioner, 46: Mohapatra, B.N., Dash, B.P. and Kar, B.C.(1993) Serum Immunoglobulins in sickle cell disease. JAPI, 41:

5 26. Balgir, R.S., Das,R.K. and Dash,B.P. (1993) Age of Menarche in Sickle Cell Haemoglobinopathy. Ind Practitioner, 46: Dash, B.P., Mittra, A and Kar, B.C. (1992) A study on the glucose uptake, pyruvate and lactate formation in red blood cells of normal, sickle cell trait and sickle cell patients. Indian J Clin Biochem, 7(2): Pani, S., Dash, B.P., Das, R.K. and Kar,B.C.(1992) G6PD deficiency and sickle cell disease in India. Indian J Hematol Blood Transf, 10: Mittra, A. and Dash, B.P. (1991) Effect of sublethal electrocution on some haematological parameters in Rattus norvegicus. Indian J Physiol Pharmacol, 35(4): Dash, B.P. and Kar, B.C. (1990) Sickle Cell Disorder. In: Elements of Management of Blood Disorders. S.N.Shukla (Editor). Ahmedabad, pp Mittra, A., Dash,B.P. and Sahu, S.(1988) Effect of sublethal electrocution on blood cholesterol level, red cell fragility, plasma glucose level and some plasma cations in Rattus norvegicus. Indian J Comp Animal Physiol, 6(2): PAPERS IN PROCEEDINGS OF CONFERENCES / SEMINARS 1. Mishra S, Dash N.C and. Dash B.P. (2009) Socio-Demographic aspects of abnormal haemoglobin related health problems in Balasore district of Orissa. Souvenir, 12 th Orissa Bigyan Congress, Bhubaneswar. pp: Dash B.P. (2008) Stem cell biology and its application to haemoglobinopathies. Souvenir, 23 rd Annual conference of APO, Orissa. pp: Mishra S, Dash B.P. and Dash N.C. (2008) Economic burden of blood transfusion on parents of haemoglobinopathy patients of Balasore district of Orissa. Social Sector Policy and Population Quality. pp: Dash B.P. (2007) DNA and Ageing. Proceeding of National Seminar on Ageing and Problems of Agerian in the Society. pp: Dash B.P. and Dash N.C. (2007) Genetic Human Health problems in Orissa: Could they be prevented and controlled? Proceedings of National Seminar on Population and Health Status in Orissa. pp: Dash B.P. and Gahan S. (2007) Prevention of Vitamin A Deficiency through Transgenic Plants. Proceedings of National Seminar on Application of Biotechnology in Special Response to Development of Transgenic Plants. pp: 4-8.

6 7. Dash B.P., Gahan S, Mittra B and Misra A.N. (2006) Biotechnological strategy for development of Vaccine to control the Acquired Immunodeficiency syndrome. Souvenir, National Level Conference on Eradication of HIV/AIDS. pp: A. Writing scientific articles in Oriya language Other Activities i. Amla Barsana (Acid Rain)", Published in Bigyanaloka. ii. "Sickle cell (Rakta Sikuli) Roga", Published in Bigyanaloka, Sambad and Hirakhanda. iii. "Sickle cell roga", Published in Anwaysana. iv. Thalassaemia Roga, Published in Bisesa Khabar. v. Haemoglobin O Manusya Swasthay, Published in Bisesa Khabar. vi. Manusya Cloning Published in Bisesa Khabar. vii. Genetic Engineering Published in Bisesa Khabar. viii. Rogo Srustikari eka bismaya protein: Prion Published in Bisesa Khabar. ix. Kutrima Rakta Published in Bisesa Khabar. x. Medicinal plants ru Medicine plants Published in Bisesa Khabar. B. Talks in All India Radio and Door Darshan (TV) : i. Sickle Cell Disease, delivered in Sanjevani programme ( ) of Door Darshan Kendra, Bhubaneswar. Orissa. ii. Rogatiku Jana," Sickle cell roga", delivered in the Kishore Sansar programme of All India Radio Sambalpur, Orissa. iii. Tume Janichhaki," Matitale Jia Kepari Rahe", delivered in the Kishore Sansar programme of All India Radio Sambalpur, Orissa.

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