2016 NON FINANCIAL RESOURCE REQUIREMENTS GPEI DONOR CONTRIBUTIONS

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1 2016 NON FINANCIAL RESOURCE REQUIREMENTS GPEI DONOR CONTRIBUTIONS Background The Global Polio Eradication Initiative (GPEI) is financed through a range of public and private donations. The Financial Resource Requirements (FRR) provides an overview of the financial activities planned for the period and corresponding contributions. Each year, Non-FRR funding enables innovations to support the eradication activities funded through the FRR, as well as funding for emergent supporting activities. This report s purpose is to acknowledge these generous and important contributions in the effort to achieve a polio-free world Global Polio Eradication Initiative Non-FRR Funding Contributions Aggregate 2016 Donor Contribution Total Non-FRR Contribution: Number of Donors: Donors: $269,472,027 5 Bill and Melinda Gates Foundation, Département des Relations Extérieures et de la Coopération de la Principauté de Monaco, Rotary International, U.S. Agency for International Development, U.S. Centers for Disease Control & Prevention Non-FRR Objective & Grantee Type Breakdown Objective Breakdown Non-FRR Objective & Activity Breakdown Objective 1: Poliovirus Detection and Interruption Objective 2: Systems Strengthening and OPV Withdrawal Objective 3, $1,724,625 Objective 4, $9,797,296 Switch, $1,337,351, $767,215 Objective 2, $71,725,762, $70,737,896 QI, $70,849,784 Research & Development, $21,359,245 Objective 1, $186,224,344 IPV, $41,463,634 Surveillance, $19,236,954 SocMob, $19,458,301 SIAs, $5,941,410 QI, $1,645,471 Immunization, $5,152,846 1

2 2016 NON FINANCIAL RESOURCE REQUIREMENTS GPEI DONOR CONTRIBUTIONS 2016 Global Polio Eradication Initiative Non-FRR Funding Contributions Aggregate Non-FRR Objective & Grantee Type Breakdown Grantee Type Breakdown Non-FRR Objective & Activity Breakdown Objective 3: Containment & Certification Objective 4: Transition Planning (Implementing) $96,360,494 $82,754,268 $59,288,125 Universities $12,668,433 Multilateral Orgs. $9,318,212 $5,854,591 (Technical Assistance) $3,227,905 $0.0 $50.0 $100.0 $150.0 Dollars Cont & Cert, $1,724,625 Transition, $9,797,296 2

3 Donor Agency: Bill and Melinda Gates Foundation 2016 Donor Contribution: Total Donor Contribution $532,599,116 a) FRR Donor Contribution: $367,488,777 % of total FRR contribution: 69% b) Non-FRR Donor Contribution: $165,110,339 % of total non-frr contribution: 31% $80.0 $70.0 $60.0 $50.0 $40.0 $30.0 $20.0 $10.0 $ $70.8 $41.5 $21.4 $11.2 $5.3 $6.2 $5.2 $0.3 $1.0 $1.6 $0.6 Surveillance SIAs SocMob/Comms Technical Assistance Quality IPV Introduction Immunization Switch Quality Research & Transition Planning Improvements Activities Improvements Development Objective 1 Objective 2 Objective 4 Objective 1 Poliovirus Detection and Interruption QI 75% 0% SIAs 6% SocMob 7% Surveillance 12% (Implementing) Universities Multilateral Orgs. - Expand independent campaign monitoring in Pakistan to identify opportunities to reduce the number of missed children and implement localized tactics and strategies to address those opportunities. - Strengthen Emergency Operations Centers (EOCs) in Pakistan and Nigeria. - Develop, enhance, and deploy technical tools to improve GIS tracking and mapping of vaccination activity in Nigeria - Enhance virtual diagnostic capabilities for remote AFP surveillance. - Operate health camps in Kano, Nigeria and strengthen routine immunization and other eradication strategies in Borno, Nigeria. - Buydown vaccines for routine immunization. (Technical Assistance) $ $20.0 $40.0 $60.0 Objective 2 Immunization Systems Strengthening and OPV Withdrawal IPV 59% Switch 2% QI 2% Immunization 7% Research & Development 30% Which GPEI grantees are executing this work? (Implementing) Universities - Identify a scaleable, low cost, standalone IPV: a) dmlt and PERC.C6; b) IPV formulation with BBio vaccine for IPV microneedle production formulation screening; c) IPV Technology Transfer; d) IPV supplement to bopv regimine; e) reduced dose IPV -Support development of a genetically-stabilized, low-cost nopv2 vaccine - Develop an antiviral to mitigate the risk of long-term viral shedding by immunodeficient individuals. - Execute the global switch from topv to bopv. Multilateral Orgs. $ $20.0 $40.0 $60.0 3

4 Donor Agency: Bill and Melinda Gates Foundation Objective 4 Transition Planning - Assess the global indemnity liabilities of BMGF's primary implementation partners, WHO and UNICEF, associated with the ramp-down of polio work. (Technical Assistance) Transition $ $0.1 $0.2 $0.3 $0.4 $0.5 $0.6 Notes: (1) FRR stands for the Financial Resource Requirements, an overview of external funding and planned GPEI activates for the period to eradicate all remaining polio cases. (2) Quality Improvement includes funding for polio program innovation (e.g., EOCs, geospatial mapping and mobile tracking). (3) IPV stands for inactivated polio vaccine, an inactivated (killed) poliovirus strains of all three poliovirus types administered by trained health workers. (4) OPV stands for oral polio vaccine, a mixture of live, attenuated (weakened) poliovirus strains of all three poliovirus types. (5) Universities include: University of California (LA and SF), MIT, Dartmouth College, University of Southampton, Georgia Institute of Technology, Aga Khan University, Universiteit Antwerpen, Duke University, Stanford, University of Virginia, Chinese Academy of Medical Sciences, and the Graduate Institute of Geneva. (6) "" includes a range of additional nonprofits, biotechnology companies and private sector partners. (7) Report excludes ($351,920) in returned funding, which will be re-allocated towards FRR and non-frr activities not detailed in this report. 4

5 Donor Agency: Département des Relations Extérieures et de la Coopération de la Principauté de Monaco 2016 Donor Contribution: Total Donor Contribution $225,490 a) FRR Donor Contribution: $156,630 % of total FRR contribution: 69% b) Non-FRR Donor Contribution: $68,860 % of total non-frr contribution: 31% $ in Thousands $20.0 $15.0 $10.0 $5.0 $ $17.2 $17.2 $17.2 $17.2 Technical Assistance Technical Assistance Containment and Certification Transition Planning Objective 1 Objective 2 Objective 3 Objective 4 Objective 1 Poliovirus Detection and Interruption In kind support from the Permanent Mission of the Principality of Monaco to the UN in Geneva (Mission permanent de la Principauté de Monaco auprés des Nations Unies à Genève $ $5.0 $10.0 $15.0 $20.0 $ in Thousands Objective 2 Immunization Systems Strengthening and OPV Withdrawal Which GPEI grantees are executing this work? In kind support from the Permanent Mission of the Principality of Monaco to the UN in Geneva (Mission permanent de la Principauté de Monaco auprés des Nations Unies à Genève $ $5.0 $10.0 $15.0 $20.0 $ in Thousands 5

6 Donor Agency: Département des Relations Extérieures et de la Coopération de la Principauté de Monaco Objective 3 Containment & Certification In kind support from the Permanent Mission of the Principality of Monaco to the UN in Geneva (Mission permanent de la Principauté de Monaco auprés des Nations Unies à Genève Cont & Cert $ $5.0 $10.0 $15.0 $20.0 $ in Thousands Objective 4 Transition Planning In kind support from the Permanent Mission of the Principality of Monaco to the UN in Geneva (Mission permanent de la Principauté de Monaco auprés des Nations Unies à Genève Transition $ $5.0 $10.0 $15.0 $20.0 $ in Thousands Notes: As enshrined in its terms of reference, the purpose of the Polio Partners Group (PPG) is: (1) to serve as the stakeholder voice for the Global Polio Eradication Initiative (GPEI) in the development and implementation of short-term and long-term polio eradication strategic plans and emergency action plans; and (2) to foster greater engagement among polio-affected countries, donors and other partners with the objective of utilizing their political, communications, programmatic and financial capabilities to ensure GPEI has the necessary political commitment and financial resources to reach the goal of polio eradication. 6

7 Donor Agency: Rotary International 2016 Donor Contribution: Total Donor Contribution $107,625,433 a) FRR Donor Contribution: $105,158,252 % of total FRR contribution: 98% b) Non-FRR Donor Contribution: $2,467,181 % of total non-frr contribution: 2% $3.0 $2.5 $2.0 $1.5 $1.0 $0.5 $ $2,467,180.8 $0.0 $0.0 $0.0 SocMob/Comms (blank) (blank) (blank) Objective 1 Objective 2 Objective 3 Objective 4 Objective 1 Poliovirus Detection and Interruption This funding allows Rotarians to directly engage with their communities and partners to raise awareness, mobilize volunteers and participate in immunization activities. SocMob $ $0.5 $1.0 $1.5 $2.0 $2.5 $3.0 Notes: n/a 7

8 Donor Agency: U.S. Agency for International Development 2016 Donor Contribution: Total Donor Contribution $59,000,000 a) FRR Donor Contribution: $43,235,000 % of total FRR contribution: 73% b) Non-FRR Donor Contribution: $15,765,000 % of total non-frr contribution: 27% $12.0 $10.0 $8.0 $6.0 $4.0 $2.0 $ $10.0 $4.0 $0.3 $0.8 $0.4 $0.3 Surveillance SocMob/Comms Technical Assistance Technical Assistance Containment and Certification Transition Planning Objective 1 Objective 2 Objective 3 Objective 4 Objective 1 Poliovirus Detection and Interruption Surveillance SocMob (Technical Assistance) USAID's polio eradication program contributes to the multi-donor, Global Polio Eradication Initiative by focusing support towards national plans to build and sustain population immunity sufficient to stop polio transmission, build and enhance facility and community-based surveillance able to detect and respond to possible polio cases, increase public trust in immunization by working with local partners to address parental concerns, working with civil society to reach the most vulnerable children in high risk areas and along international borders, and assisting in early detection and outbreak response to any new polio cases found in previously polio-free areas. (Implementing) $ $5.0 $10.0 $15.0 Objective 2 Immunization Systems Strengthening and OPV Withdrawal Which GPEI grantees are executing this work? (Technical Assistance) USAID looks for opportunities to leverage our investments in polio to strengthen routine immunization and the broader health systems. This includes strengthening partnerships, using polio micro plans in support of routine immunization, supporting newborn and pregnant women tracking and mapping, broader behavior change communication and messaging to support immunization, integrated disease surveillance, and support for vlmis. USAID's support to the CORE Group Polio Project specifically supports NGOs to foster strong community engagement, monitor RI sessions, monitor cold chain equipment, assist to validate the switch from trivalent to bivalent OPV, and support broader disease surveillance at the community level. Maternal Child Survival Program (MCSP) has also worked on the switch, IPV introduction, transition planning and other immunization / links with RI $ $0.2 $0.4 $0.6 $0.8 8

9 Donor Agency: U.S. Agency for International Development Objective 3 Containment & Certification Cont & Cert (Technical Assistance) (Implementing) USAID's support to the CORE Group Polio Project supports NGOs work on containment and supports the secretariat model, a formal network of full-time directors and several technical and administrative personnel who organize and harmonize NGO/PVO activities for immunization, supplemental immunization activities, surveillance and other activities. The Secretariat engages closely with local governments and partners to be involved in the certification processes, as well as to develop and implement vaccination coverage surveys, campaign monitoring, workshops, meetings, mapping, micro-planning, training, babytracking, identifying and revisiting refusal households to encourage immunization acceptance, conducting community-based surveillance and other critical polio eradication activities. USAID staff is also involved in the containment and certification process providing technical assistance to countries. $ $0.1 $0.1 $0.2 $0.2 $0.3 Objective 4 Transition Planning (Technical Assistance) The Core Group Polio Project, MCSP and USAID staff are involved in legacy and transition planning discussions at the country and global level to ensure the contributions made by Global Polio Eradication Initiative and multi-donors are well transitioned and that the lessons learned in polio eradication are recorded. Transition (Implementing) $ $0.0 $0.1 $0.1 $0.2 Notes: n/a 9

10 Donor Agency: U.S. Centers for Disease Control & Prevention 2016 Donor Contribution: Total Donor Contribution $169,000,000 a) FRR Donor Contribution: $82,939,353 % of total FRR contribution: 49% b) Non-FRR Donor Contribution: $86,060,647 % of total non-frr contribution: 51% $80.0 $70.0 $60.0 $50.0 $40.0 $30.0 $20.0 $10.0 $ $70.1 $4.1 $0.7 $0.7 $0.3 $1.3 $8.9 Surveillance SIAs SocMob/Comms Technical Assistance Switch Containment and Certification Transition Planning Objective Objective 3 Objective 4 Objective 1 2 Objective 1 Poliovirus Detection and Interruption SIAs 1% SocMob 1% Surveillance 5% (Implementing) The goal of this funding is to leverage CDC experitise in training, surveillance, program execution, management, and immunization activities to help the three endemic countries of Nigeria, Pakistan, and Afghanistan to be able to achieve interruption in % $ $20.0 $40.0 $60.0 Objective 2 Immunization Systems Strengthening and OPV Withdrawal Which GPEI grantees are executing this work? This funding was dedicated to ensuring a smooth transition from using trivalent OPV to bivalent OPV in April 2016, especially from a laboratory and containment standpoint. Switch $ $0.1 $0.1 $0.2 $0.2 $0.3 $0.3 $0.4 10

11 Donor Agency: U.S. Centers for Disease Control & Prevention Objective 3 Containment & Certification Multilateral Orgs. Achieving and maintaining certification-level surveillance is the primary goal for this funding. There is also a secondary goal of making sure that containment of type-2 polio continues on schedule. Cont & Cert $ $0.2 $0.4 $0.6 $0.8 $1.0 $1.2 Objective 4 Transition Planning (Technical Assistance) (Implementing) The intent of the programmatic funding is to strengthen routine immunization in high risk countries to minimize the chances of a successful importation of polio. The funding is also intended to systemically prepare countries with the most polio assets to be prepared for a post-polio world when funding for polio will end, so that people, systems, and knowledge are retained and used for a broader public health purpose, especially in the realm of immunization. Transition $ $2.0 $4.0 $6.0 $8.0 $10.0 Notes: n/a 11