23 May 3 June Les Pensières Veyrier-du-Lac (French Alps) Application deadline: 15 November 2015
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1 17 th Les Pensières Veyrier-du-Lac (French Alps) 23 May 3 June 2016 Application deadline: 15 November 2015 For over 15 years, ADVAC has provided senior decision-makers and scientists in the field of vaccines with a comprehensive overview of the latest advances, from immunology to vaccine development, including clinical trials. The social, economic, political and ethical issues of vaccination are also addressed during the lectures, which are given by a faculty of leading global experts. Organised by Fondation Mérieux and University of Geneva with the co-sponsorship of European Commission (ADITEC project) World Health Organization and European Centre for Disease Prevention and Control (ECDC) Centers for Disease Control and Prevention (CDC) European Society for Paediatric Infectious Diseases (ESPID) Johns Hopkins Bloomberg School of Public Health National Foundation for Infectious Diseases (NFID) National Institutes of Health (NIH) and Fogarty International Center National Vaccine Programme Office (NVPO) Fellowships for developing country participants provided by Bill & Melinda Gates Foundation
2 Neal Halsey Professor - Department of International Health at the Bloomberg School of Public Health ADVAC helps fulfill the prescient vision of Dr. Charles Mérieux to gather scientists and other health professionals to address the never-ending challenges from infectious diseases. Past ADVAC participants have helped bring new lifesaving vaccines to countries throughout the world and they are playing key roles in the development of new vaccines.
3 To facilitate critical decision-making in vaccinology by providing participants with a comprehensive overview of the field, from immunology to vaccine development, including clinical trials and the social, economic, political and ethical issues of vaccination. PROVISIONAL PROGRAMME SESSION 1 THE MULTI-FACETED NATURE OF VACCINOLOGY Vaccinology overview in the global perspective Impact of vaccination on disease epidemiology Are vaccines always cost-effective? Public perception in new vaccination strategies Vaccine development as an iterative process Industrial vision of vaccinology SESSION 2 HOW VACCINES WORK How are vaccine responses elicited? Immunological basis for responses to mucosal vaccines Immunological correlates of immunity Vaccines and immunological memory Long-term protection SESSION 3 DECISION-MAKING IN VACCINE R&D New approaches to vaccine development and delivery How do vaccines cause adverse events From pre-clinical research to vaccine development Vaccine adjuvants: pragmatic approaches SESSION 4 ASSESSING VACCINES IN CLINICAL TRIALS (I) Sequential stages of clinical trials and overview of issues to be considered How to design, recruit volunteers for,and analyze the results of selected phase II trials How to design a phase II trial SESSION 5 ASSESSING VACCINES IN CLINICAL TRIALS (II) Lessons from pitfalls experienced in the registration process Lessons from organizing a phase III trial Designing and analysing the results of 3 selected phase III trials SESSION 6 VACCINE SAFETY Lessons from previous adverse effects of vaccination and assessment of causal relationships Immunological safety of vaccination Post-licensure surveillance and assessment of adverse effects Immunization safety in developing country vaccination programs SESSION 7 ETHICAL ISSUES Ethical issues related to clinical trials - Revisiting the Helsinki Declaration Group exercises SESSION 8.1 INTRODUCING NEW VACCINES INTO VACCINATION PROGRAMMES Approaches to help the decision-making process Role of epidemiology and the economy Case-specific studies: Meningococcal vaccines, Combination vaccines, Influenza-vaccination strategies, Pneumococcal conjugates, HPV, Rotavirus, JE, Dengue Group exercises: selected countries SESSION 8.2 INTRODUCING NEW VACCINES INTO VACCINATION PROGRAMMES Vaccination in the elderly Influenza biology New vaccines Rotavirus vaccines SESSION 9 SELECTING APPROPRIATE VACCINATION STRATEGIES Vaccines for maternal-neonatal health Vaccination schedules SESSION 10 FACING THE MEDIA Introduction to media dynamics: How to best deliver vaccinology-related messages to different interest groups
4 CORE FACULTY ROY ANDERSON Imperial College London, UK EDWIN ASTURIAS Children s Hospital Colorado, USA RON DAGAN Soroka Medical Center, Israel GIUSEPPE DEL GIUDICE Novartis, Italy PHILIPPE DUCLOS WHO, Switzerland JANET ENGLUND Seattle Children s Hospital, USA JUHANI ESKOLA National Public Health Institute, Finland ADAM FINN University of Bristol, UK BERNARD FRITZELL BFL Conseils, France DAVID GOLDBLATT Institute of Child Health, University College London, UK DEBORAH HALL Journalist, UK NEAL HALSEY J.H. Bloomberg School of Public Health, USA CAROLE HEILMAN NIAID, NIH, USA LUC HESSEL Emeritus, Sanofi Pasteur MSD, France PAUL-HENRI LAMBERT MYRON LEVINE University of Maryland, USA MARK MILLER Fogarty International Center, NIH, USA HANNA NOHYNEK National Institute for Health and Welfare, Finland STANLEY PLOTKIN Vaxconsult, USA DAVID SALISBURY Department of Health, UK CLAIRE-ANNE SIEGRIST CHRIS WILSON Bill & Melinda Gates Foundation, USA SCIENTIFIC COMMITTEE PAUL-HENRI LAMBERT (course director) STANLEY PLOTKIN (senior scientific advisor) Vaxconsult, USA EDWIN ASTURIAS Children s Hospital Colorado, USA ARNOLD BOSMAN ECDC, Sweden PHILIPPE DUCLOS WHO, Switzerland ADAM FINN University of Bristol, UK BRUCE GELLIN NVPO, USA BRAD GESSNER AMP, France NEAL HALSEY J.H. Bloomberg School of Public Health, USA CAROLE HEILMAN NIAID, NIH, USA CHRISTOPHE LONGUET Fondation Mérieux, France ALISON MAWLE CDC, USA CHARLES MGONE EDCTP, the Netherlands MARK MILLER Fogarty International Center, NIH, USA HANNA NOHYNEK THL, Finland SUSAN REHM NFID, USA CLAIRE-ANNE SIEGRIST CHRIS WILSON Bill & Melinda Gates Foundation, USA
5 OVER 1,000 ADVAC ALUMNI WORLDWIDE Through alumni get-together meetings and a variety of on-line resources, ADVAC continues to bring together vaccinologists from all cultures throughout the world to discuss the major challenges of the day. The relationships forged at ADVAC remain strong through meetings organized during international conferences such as SAGE or ESPID. The field of vaccinology is constantly changing. Each year, ADVAC alumni are given exclusive access to podcasts and training material from the current ADVAC course on a dedicated website for alumni on Fondation Mérieux s GLOBE network. A newsletter featuring alumni interviews, a new e-library, and highlights from the alumni get-together meetings are also available on:
6 65 HIGHLY SELECTED PARTICIPANTS WHO SHOULD APPLY? PROGRAMME FEES 65 INTERNATIONAL SPEAKERS 13 INTERACTIVE SESSIONS 11 DAYS OF KNOWLEDGE-SHARING 16 SUCCESSFUL YEARS 8 CASE STUDIES 2 POSTER SESSIONS 1 DIPLOMA AND CME CERTIFICATE A NETWORK OF OVER 1,000 ALUMNI ADVAC has been awarded 60 CME credits by the European Board for the Accreditation of CME in Infectious Diseases (EBAID) and by the European Union of Medical Specialists (UEMS) Scientists and decision-makers involved in vaccine development, in the elaboration of new vaccination strategies or in policy decisions related to the introduction of new vaccines in public health programmes, at national or international levels. For both the public and private sectors. Apply on line through Deadline: 15 November 2015 at 12:00 GMT. SELECTION CRITERIA Participants (maximum 65) will be selected by the international scientific committee, according to their: Educational background, Involvement in vaccinology, Decision-making responsibility in vaccinology, Expected impact of the course at personal, institutional and national levels (maximum one per institution). Participants from academic/governmental institutions & NGOs benefit from reduced fees: 3,600 VAT included Participants from industry: Industry sponsors (for sponsorship levels of 10,000 and over): 6,400 Other industry participants (including SMEs): 11,400 * The fees include tuition, course materials, accommodation costs (2,400 including VAT) for the full period of the course. If selected, participants will be required to pay all fees in full to confirm their participation. VENUE The course will be held at Fondation Mérieux s conference centre, Les Pensières, at Veyrierdu-Lac, on the scenic banks of Lake Annecy (France). Lodging will be arranged in nearby hotels. CONTACT Katia Mielczarek katia.mielczarek@fondation-merieux.org or advac@unige.ch See additional info on Credit photo: E. BERGOEND A. BOUVIER - théra - RCS Lyon B
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