FMD epidemic models: update on recently published/developed models
|
|
- Barrie Fields
- 5 years ago
- Views:
Transcription
1 Closed Session of the EuFMD Research Group Kranska Gora, Slovenia 23 th 25 th September 2009 FMD epidemic models: update on recently published/developed models Antonello Di Nardo Institute for Animal Health, Pirbright UK
2 Why model FMD? Strategic (in peacetime ) Investigate FMD epidemiology and behaviour under local conditions Investigate the effectiveness and efficiency of alternative mitigation strategies and of surveillance and monitoring programmes Investigate the likely cost of outbreaks of different characteristics Provide a resource for training awareness Tactical (during outbreak) Provide information about the likely effectiveness and efficiency of mitigation strategies under existing outbreak conditions Provide information about resource allocation strategies Provide limited scale-dependent forecasting (???)
3 Model design Deterministic model Values of input parameters are fixed Results do not take account of random variation (i.e. variability) Same result for every iteration Stochastic model Describes processes/events subject to random variation Parameters values are used in form of probability distribution Variability leads to outcome with probability Different results for every iteration (Monte-Carlo sampling)
4 Model design Compartmental models Consider individual diversity within population Units can exist in mutually exclusive states Modelling the progress of epidemic in compartment/state Transition between states as events occur Susceptible β Infectious ν Recovered β Infection rate ν Rate of recovery
5 Model design Spatial factors Non-spatial Pseudo-spatial (grids/lattice) Spatially explicit (distance/points/regions)
6 Baseline epidemic model
7 Model input (Matthews and Woolhouse, 2005)
8 Model building Objectives clearly specified Details of data and knowledge of parameters are needed Confirm that type of output designed is generated Test the sensitivity of the model input variables stability Establish if the model behaves like the biological system that it is designated to mirror assessed against data not used in its construction precision specified in advance Assessment of a theory Generality, simplicity, precision, refutedness, testedness (Thrusfield, 2007)
9 Models used in 2001 Imperial model (Ferguson et al., 2001) Cambridge-Edinburgh model (Keeling et al., 2001) InterSpread model (Morris et al., 2001) Imperial Model Cambridge-Edinburgh Model InterSpread Model Type Deterministic (differential equations) Stochastic (microsimulation) Stochastic (microsimulation) Parameters Few Few Many Spatially explicit Different species Airborne spread Different transmission mechanism Intra-herd transmission dynamics Logistic resources Vaccination strategies
10 Current FMD model projects AusSpread-DAFF model (Garner and Backett, 2005) North American Animal Disease Spread (NAADS) model (Harvey et al., 2006) InterSpread Plus model (Stevenson et al., 2006) Exodis model (Risk-Solutions, 2006) Automata model (Ward et al., 2007) Multiscale Epidemiological/Economic Simulation (MESA) model (Kostova, 2007) Davis Animal Disease Simulation (DADS) model (Carpenter, 2007)
11 AusSpread model Stochastic (Monte-Carlo based) State-transition SLIR (micro-simulation) developed from a Marchov-chain Spatially explicit (real farm boundaries or point location data) developed and operates within a GIS environment (MapBasic /MapInfo ) Farm-based and specie-specific (7 default farm types and wildlife) Simulating disease spread Saleyard spread Airborne spread Farm-to-farm spread Modelling mitigation based on AUSVET-PLAN for FMD Quarantine and movement restrictions Stamping-out Surveillance (active/passive) Tracing Pre-emptive slaughter Vaccination Resources
12 NAADSM model Stochastic (Monte-Carlo based) State-transition (micro-simulation) Spatially explicit Herd-based and specie-specific Simulating disease spread Airborne spread Farm-to-farm spread (direct/indirect contact) Influenced by relative locations and distances Modelling mitigation Quarantine and movement restrictions Stamping-out Surveillance (active/passive) Tracing Pre-emptive slaughter Vaccination Resources (priorities and costs)
13 NAADSM model 3 experimental versions Cheyenne quarantined units are allowed to be recipients of direct contact Laramie destroyed unites are allowed to be recipients of indirect contact developed to simulate FMD spread among livestock premises by wildlife Riverton units that have progressed to naturally immune state are not included in the destruction programme developed to explore alternative destruction strategies for HPAI
14 InterSpread Plus model Stochastic (Monte-Carlo based) State-transition (micro-simulation) Spatially explicit (polygonal units or point location data) Farm-based and specie-specific Simulating disease spread Movement spread (distance dependent) Local spread (distance dependent) Airborne spread Modelling mitigation Movement restrictions/standstill Depopulation Surveillance intensity (active/passive) Tracing (backward and forward) Pre-emptive slaughter Vaccination Resources
15 Exodis model Stochastic (Monte-Carlo based) State-transition (micro-simulation) Spatially explicit (Kernel density function) Farm-based and specie-specific Simulating disease spread Airborne spread Intra-herd spread Farm-to-farm spread Modelling mitigation Quarantine and movement restrictions Stamping-out Surveillance (active/passive) Tracing Pre-emptive slaughter Vaccination Resources
16 MESA model Stochastic State-transition SLIR (micro-simulation) Spatially explicit Individual-based and specie-specific Simulating disease spread Saleyard spread Airborne spread Farm-to-farm spread (direct/indirect contact) Modelling mitigation based on USDA FMD Response Plan Quarantine and movement restrictions Stamping-out Surveillance (active/passive) Tracing (backward and forward) Minimal time to obtain freedom-from-disease following the last case (42 days)
17 DADS model Stochastic (Monte-Carlo based) State-transition SLIR (micro-simulation) Spatially explicit Herd-based and specie-specific Simulating disease spread Airborne spread Farm-to-farm spread (direct/indirect contact) Modelling mitigation Quarantine and movement restrictions Stamping-out Surveillance (active/passive) Tracing Pre-emptive slaughter Vaccination Resources
18 Automata model Stochastic (joint probability threshold) State-transition SLIR (micro-simulation) Spatially explicit (geographical-automata) Herd-based and specie-specific Simulating disease spread Probabilistic inter-herd-distance dependent Product of neighbouring density probability (based on ecological site capacity) Repetitive application of transmission rules (complex spatial behaviour) No modelling mitigation Developed to explore FMD spread within/between domestic and wildlife populations
19 Models validation current projects Quadrilateral (QUADs) country model comparison project (2005) AusSpread NAADSM InterSpread Plus 1. Comparison of conceptual models (formal review of model description) 2. Comparison of 6 scenarios assessing spread mechanism 3. Comparison of 5 scenarios control measures Statistically significant difference among number of IPs and temporal/spatial spread prediction by the 3 models Difference in the size of outbreak areas EpiLab (2007) Imperial, Cambridge-Edinburgh, InterSpread Plus, DADS DISCONVAC (2009) InterSpread Plus, DADS, NAADSM, others
20 Models problems and issues Complexity Lack of transparency Impossible to be reproduced Robustness of results difficult to assess Significant number of unknown parameters Still based on expert opinion (< accuracy) Lack of intra-herd/within-herd dynamics modelling Exiguous experimental data Local-scale based Providing regional guidance, but never at tactical level Availability and quality of data Accurate and extensive input data Validation Replication of one outbreak parameterising with data from another Endemic models??? Wildlife??? Multiple FMD serotype incursions???
21 Models uncertainty and caution All the model are wrong Model is a value-added in Decision Support System Useful for resource planning/allocation Useful for exploring what if scenario Are not good at predicting random behaviour Models only reflect the biases of the modeller and lack of objectivity Be careful of models posing as truth (lack of validation) Keep it simple, keep it flexible, make it transparent
22 Acknowledges Keith Sumption, Nadia Rumich (EuFMD) David Paton, David Schley (IAH) Michael Ward (University of Sydney) Michael Thrusfield (University of Edinburgh)
Outline. Decision Support Systems. Mark Bronsvoort, MRCVS Centre for Tropical Veterinary Medicine, University of Edinburgh
Decision Support Systems (making hard decisions with imperfect informatio Mark Bronsvoort, MRCVS Centre for Tropical Veterinary Medicine, University of Edinburgh 1 Outline What are decision support systems
More informationPutting it together: The potential role of modeling to explore the impact of FMD
Putting it together: The potential role of modeling to explore the impact of FMD Mo Salman Animal Population Health Institute Colorado State University m.d.salman@colostate.edu And Melissa McLaws European
More informationThe Animal Health Quadrilateral Epiteam International collaboration on Foot-and- Mouth Disease simulation modelling for emergency preparedness.
Appendix 10 The Animal Health Quadrilateral Epiteam International collaboration on Foot-and- Mouth Disease simulation modelling for emergency preparedness. Dubé Caroline 1,*, Garner G 2, Sanson R 3, Harvey
More informationEvaluating vaccination for foot-and-mouth disease control an international study
Evaluating vaccination for foot-and-mouth disease control an international study Garner MG, Gauntlett FA, Sanson RL, Stevenson MA, Forde-Folle K, Roche SE, Birch C, Owen K, Dube C, Rooney J, Corso B, Cook
More informationModelling the Dynamic of the Foot-and Mouth Disease in England 2001
Modelling the Dynamic of the Foot-and Mouth Disease in England 2001 Seminar on Veterinary Epidemiology Franz Rubel Budapest, 28 May 2003 Mathematical Epidemiology Group, Institute for Medical Physics and
More informationFMD Progressive Control Pathway. Peter de Leeuw, DVM, PhD
FMD Progressive Control Pathway Peter de Leeuw, DVM, PhD What is the PCP-FMD? A development tool, with a stepwise approach to improve FMD control in FMD-endemic countries Each step (or PCP-Stage) is defined
More informationRisk Assessment in the context of Bio-risk Management
Risk Assessment in the context of Bio-risk Management 1 Some preliminary information 2 Hazard 3 Hazard It is a qualitative notion It is a biological, chemical or physical agent that may have adverse health
More informationThe North American Animal Disease Spread Model: A simulation model to assist decision making in evaluating animal disease incursions
Preventive Veterinary Medicine xxx (2007) xxx xxx www.elsevier.com/locate/prevetmed The North American Animal Disease Spread Model: A simulation model to assist decision making in evaluating animal disease
More informationEarly decision indicators to predict the severity of an FMD outbreak
Early decision indicators to predict the severity of an FMD outbreak A simulation modelling study by the QUADS epiteam C. Birch, T. Boyer, C. Cook, C. Dubé, F.D. Dorea, K. Forde Folle, M.G. Garner, K.
More informationCHAPTER 8 ESTIMATION OF THE OUTBREAK COST
59 CHAPTER 8 ESTIMATION OF THE OUTBREAK COST Due to uncertainty about the dissemination rate and the large disparity from previously published simulations of FMD, seven scenarios reflecting different assumptions
More informationCHAPTER 7 MODELING A FMD OUTBREAK IN TULARE COUNTY
Potential Impact of Foot-and-Mouth Disease in California 51 CHAPTER 7 MODELING A FMD OUTBREAK IN TULARE COUNTY The value of animal health surveillance and monitoring services equals the expected losses
More informationDevelopments in FMD-free countries
Developments in FMD-free countries Marleen Werkman Warwick Infectious Disease Epidemic Research group, University of Warwick, UK M.Werkman@warwick.ac.uk University of Warwick Mike Tildesley Matt Keeling
More informationModelling FMD at European scale
Modelling FMD at European scale No movement ban County level movement ban Buhnerkempe, Tildesley, Lindström, Grear, Portacci, Miller, Lombard, Werkman, Keeling, Wennergren, Webb. 2014. PLoS One The process
More informationThe Progressive Control Pathway (PCP) for FMD control
The Progressive Control Pathway (PCP) for FMD control Peter de Leeuw, DVM, PhD Senior Veterinary Advisor FAO 1 What is the PCP-FMD? A development tool, with a stepwise approach to improve FMD control in
More informationModeling the impact of vaccination control strategies on a foot and mouth disease outbreak in the Central United States
This is the author s manuscript for publication. The publisher-formatted version may be available through the publisher s web site or your institution s library. Modeling the impact of vaccination control
More informationInvestigating the benefits of an adaptive management approach involving emergency vaccination using simulated FMD outbreaks in New Zealand
Investigating the benefits of an adaptive management approach involving emergency vaccination using simulated FMD outbreaks in New Zealand Robert Sanson, Zhidong Yu, Tom Rawdon, Mary van Andel Objectives
More informationStanding Technical Committee Report
Standing Technical Committee Report David Paton Rome April 2013 Overview Jerez meetings and conclusions Policy recommendations Research highlights, GFRA research report Research needs, themes for new concepts
More informationA modelling programme on bio-incidents. Submitted by the United Kingdom
MEETING OF THE STATES PARTIES TO THE CONVENTION ON THE PROHIBITION OF THE DEVELOPMENT, PRODUCTION AND STOCKPILING OF BACTERIOLOGICAL (BIOLOGICAL) AND TOXIN WEAPONS AND ON THEIR DESTRUCTION 29 July 2004
More informationUse of epidemic models in planning pandemic mitigation
Use of epidemic models in planning pandemic mitigation Neil Ferguson Dept. of Infectious Disease Epidemiology Faculty of Medicine Imperial College Introduction Modelling epidemic control background. Likely
More informationOutbreak Terminology: Phases, Zones and Premises. Dr. Patrick Webb Director, Swine Health Programs
Outbreak Terminology: Phases, Zones and Premises Dr. Patrick Webb Director, Swine Health Programs Thanks for the slides Dr. Jim Roth, Iowa State University Dr. Jon Zack, USDA APHIS VS Consequences of FMD
More informationCHAPTER 3 CONTROL AND ERADICATION OF FMD
Potential Impact of Foot-and-Mouth Disease in California 13 CHAPTER 3 CONTROL AND ERADICATION OF FMD The major factors influencing eradication of a FMD outbreak are: Prompt identification and elimination
More informationNational FMD Response Planning
National FMD Response Planning Proactive Risk Assessment to Support and Managed Preparedness Movement of Livestock and Poultry Timothy J. Goldsmith DVM, MPH, DACVPM Center for Animal Health and Food Safety
More informationPreventive Veterinary Medicine
Preventive Veterinary Medicine 88 (2009) 286 297 Contents lists available at ScienceDirect Preventive Veterinary Medicine journal homepage: www.elsevier.com/locate/prevetmed Simulation of foot-and-mouth
More informationMODELLING INFECTIOUS DISEASES. Lorenzo Argante GSK Vaccines, Siena
MODELLING INFECTIOUS DISEASES Lorenzo Argante GSK Vaccines, Siena lorenzo.x.argante@gmail.com GSK IN A NUTSHELL GSK VACCINES - GLOBAL PRESENCE SIENA RESEARCH AND DEVELOPMENT (R&D) SITE EXPLORATORY DATA
More informationScientific Opinion on sheep pox and goat pox - first part
Scientific Opinion on sheep pox and goat pox - first part EFSA-Q-2013-00918 Alessandro Broglia - ALPHA Unit SCOFCAH, 3 rd July BACKGROUND Sheep pox and goat pox (SPP/GTP) are endemic in Africa north of
More informationA simulation model of intraherd transmission of foot and mouth disease with reference to disease spread before and after clinical diagnosis
J Vet Diagn Invest 16:11 16 (2004) A simulation model of intraherd transmission of foot and mouth disease with reference to disease spread before and after clinical diagnosis Tim E. Carpenter, 1 Mark C.
More informationModeling classical swine fever spread using a spatial hybrid model
XXI Congreso de Ecuaciones Diferenciales y Aplicaciones XI Congreso de Matemática Aplicada Ciudad Real, 21-25 septiembre 2009 (pp. 1 8) Modeling classical swine fever spread using a spatial hybrid model
More informationFMD VACCINES AND THEIR USE IN VACCINATION PROGRAMMES: THEORY AND PRACTICE
FMD VACCINES AND THEIR USE IN VACCINATION PROGRAMMES: THEORY AND PRACTICE Chris Bartels, Melissa McLaws, Naser Rasouli, Theodore Knight-Jones, Keith Sumption Endemic FMD region Context EUFMD project activities
More informationSimulating Foot-and-Mouth Disease in the United States using the Animal Disease Spread Model
Simulating Foot-and-Mouth Disease in the United States using the Animal Disease Spread Model Melissa Schoenbaum, Dawit Assefa, Lindsey Holmstrom, Amy Delgado USDA APHIS VS STAS CEAH Fort Collins, Colorado
More informationFMD Progressive Control Pathway (PCP-FMD)
FMD Progressive Control Pathway (PCP-FMD) Gunel Ismayilova European Commission for the Control of Foot-and-Mouth Disease 7 th Regional FMD West Eurasia Roadmap Meeting, 6-8 April, 2016 Outline of this
More informationThe mathematics of diseases
1997 2004, Millennium Mathematics Project, University of Cambridge. Permission is granted to print and copy this page on paper for non commercial use. For other uses, including electronic redistribution,
More informationNational Rift Valley Fever Contingency Plan
National Rift Valley Fever Contingency Plan Dr Austine Bitek Zoonotic Disease Unit Ministry of Agriculture, Livestock and Fisheries Rift Valley Fever Inter Regional Conference Djibouti, 21 23 April 2015
More informationDynamics and Control of Infectious Diseases
Dynamics and Control of Infectious Diseases Alexander Glaser WWS556d Princeton University April 9, 2007 Revision 3 1 Definitions Infectious Disease Disease caused by invasion of the body by an agent About
More informationSimulation of a classical swine fever outbreak in rural areas of the Republic of Serbia
Veterinarni Medicina, 60, 2015 (10): 553 566 Original Paper Simulation of a classical swine fever outbreak in rural areas of the Republic of Serbia S. Stanojevic 1, M. Valcic 2, S. Stanojevic 3, S. Radojicic
More informationScienceDirect - Research in Veterinary Science : Mathematical modelli he foot and mouth disease epidemic of 2001: strengths and weaknesses
Login: Register Home Browse Search My Settings Alerts Help Quick Search All fields Author Journal/book title Volume Issue Page Advanced Search Research in Veterinary Science Volume 73, Issue 3, December
More informationRapid Effective Trace-Back Capability Value in Reducing the Cost of a Foot and Mouth Disease Event
Rapid Effective Trace-Back Capability Value in Reducing the Cost of a Foot and Mouth Disease Event Amy D. Hagerman Post-doctoral Research Associate The ational Center for Foreign Animal and Zoonotic Disease
More informationFOOT AND MOUTH DISEASE : VETERINARY RISK ASSESSMENT (VRA RD6)
FOOT AND MOUTH DISEASE : VETERINARY RISK ASSESSMENT (VRA RD6) What is the risk of new outbreaks of FMD, or findings of existing but undisclosed disease, outside the existing surveillance zone and enhanced
More informationFAD PReP STRATEGY DOCUMENT CLASSIFICATION OF PHASES AND TYPES OF A FOOT-AND-MOUTH DISEASE OUTBREAK AND RESPONSE
FAD PReP STRATEGY DOCUMENT CLASSIFICATION OF PHASES AND TYPES OF A FOOT-AND-MOUTH DISEASE OUTBREAK AND RESPONSE DRAFT MARCH 2013 DRAFT GUIDELINES FOR CLASSIFICATION OF PHASES AND TYPES OF AN FMD OUTBREAK
More informationEconomic Investigation of Mitigation of Foreign Animal Disease Introduction
Economic Investigation of Mitigation of Foreign Animal Disease Introduction Levan Elbakidze Texas A&M University Department of Agricultural Economics This research is supported by the National Center for
More informationWHEN FMD GOES WILD LINKING ECOLOGY, EPIDEMIOLOGY AND SURVEILLANCE. Sergei Khomenko, Tsviatko Alexandrov, Naci Bulut, Sinan Aktas, Keith Sumption
WHEN FMD GOES WILD LINKING ECOLOGY, EPIDEMIOLOGY AND SURVEILLANCE Sergei Khomenko, Tsviatko Alexandrov, Naci Bulut, Sinan Aktas, Keith Sumption 40TH GENERAL SESSION OF THE EUROPEAN COMMISSION FOR THE CONTROL
More informationStructured models for dengue epidemiology
Structured models for dengue epidemiology submitted by Hannah Woodall for the degree of Doctor of Philosophy of the University of Bath Department of Mathematical Sciences September 24 COPYRIGHT Attention
More informationThe use of models in contingency planning. Anette Boklund, DVM, ph.d.
The use of models in contingency planning Anette Boklund, DVM, ph.d. Models in relation to contingency Risk related to Import of disease to Herd Country Europe Spread Within a herd Between herds Between
More informationThe Progressive Control Pathway for FMD control (PCP-FMD)
The Progressive Control Pathway for FMD control (PCP-FMD) Principles, Stage Descriptions and Standards Accompanying explanatory documents will address specific items such as laboratory support and PVS
More informationEpidemiology and surveillance of animal diseases
REPIVET RESEPA workshop Epidemiology and surveillance of animal diseases Tunis 1-2 December 2015 Tunis 1-2 December 2015 EuFMD - Who we are and what we do A commission of 37 member states; newest member
More informationANIMAL HEALTH SURVEILLANCE
291 Annex 33a CHAPTER 1.4. ANIMAL HEALTH SURVEILLANCE Article 1.4.1. Introduction and objectives 1) In general, surveillance is aimed at demonstrating the absence of infection or infestation, determining
More informationFMD Preparedness and Response: Overview of Capabilities And Critical Activities
FMD Preparedness and Response: Overview of Capabilities And Critical Activities NIAA FMD Symposium, April 18, 2013 Jon Zack, DVM USDA APHIS Veterinary Services Emergency Management and Diagnostics Preparing
More informationDISSERTATION CONSTRUCTION AND EVALUATION OF EPIDEMIOLOGIC SIMULATION MODELS FOR THE WITHIN- AND AMONG-UNIT SPREAD AND CONTROL OF INFECTIOUS
DISSERTATION CONSTRUCTION AND EVALUATION OF EPIDEMIOLOGIC SIMULATION MODELS FOR THE WITHIN- AND AMONG-UNIT SPREAD AND CONTROL OF INFECTIOUS DISEASES OF LIVESTOCK AND POULTRY Submitted by Aaron Reeves Department
More informationMathematics of Infectious Diseases
Mathematics of Infectious Diseases Zhisheng Shuai Department of Mathematics University of Central Florida Orlando, Florida, USA shuai@ucf.edu Zhisheng Shuai (U Central Florida) Mathematics of Infectious
More informationFOOT-AND-MOUTH DISEASE (FMD) VIRUSES THE AIRBORNE TRANSMISSION OF. Elisabeth Schachner, Claudia Strele and Franz Rubel
THE AIRBORNE TRANSMISSION OF FOOT-AND-MOUTH DISEASE (FMD) VIRUSES A contribution to the MATHEPI - project, supported by Austrian Federal Ministry for Health and Women (FMHW) Elisabeth Schachner, Claudia
More informationThe global control of FMD; challenges and opportunities
EuFMD-Erice 2008 The global control of FMD; challenges and opportunities Keith Sumption, Secretary, European Commission for the Control of Foot-and-Mouth Disease (EuFMD), Food-and-Agriculture Organization
More informationFoot and Mouth Disease Continuity of Business Planning for the U.S. Dairy Industry
Foot and Mouth Disease Continuity of Business Planning for the U.S. Dairy Industry Pam Hullinger DVM, MPVM, DACVPM Veterinary Epidemiologist, Lecturer Department of Veterinary Medicine and Epidemiology
More informationAgent-Based Models. Maksudul Alam, Wei Wang
Agent-Based Models Maksudul Alam, Wei Wang Outline Literature Review about Agent-Based model Modeling disease outbreaks in realistic urban social Networks EpiSimdemics: an Efficient Algorithm for Simulating
More informationUpdate to Iowa Foot and Mouth Disease (FMD) and Livestock Emergency Management Plans
Update to Iowa Foot and Mouth Disease (FMD) and Livestock Emergency Management Plans James A. Roth, DVM, PhD Center for Food Security and Public Health College of Veterinary Medicine Iowa State University
More information7th Regional FMD West Eurasia Roadmap Meeting The incursion of new strain of FMD virus on the territory of Armenia
7th Regional FMD West Eurasia Roadmap Meeting The incursion of new strain of FMD virus on the territory of Armenia Satenik Kharatyan Head of laboratory on diagnosis of infectious diseases of farm animals
More informationAssessing the efficacy of vaccination strategies in curbing epidemics of Foot- and Mouth Disease in The Netherlands
Assessing the efficacy of vaccination strategies in curbing epidemics of Foot- and Mouth Disease in The Netherlands Boender, G.J., Hagenaars, T.J., van Roermund, H.J.W. and de Jong, M.C.M. Animal Sciences
More informationBenefit-cost analysis of animal identification for disease prevention and control
Rev. sci. tech. Off. int. Epiz., 2001, 20 (2), 385-405 Benefit-cost analysis of animal identification for disease prevention and control W.T. Disney (1), J.W. Green (1), K.W. Forsythe (1), J.F. Wiemers
More informationOIE Situation Report for Avian Influenza
OIE Situation Report for Avian Influenza Latest update: 08/05/2017 This report presents an overview of current disease events reported to the OIE by its Members. The objective is to describe what is happening
More informationOIE Situation Report for Highly Pathogenic Avian Influenza
OIE Situation Report for Highly Pathogenic Avian Influenza Latest update: 30/06/2018 The epidemiology of avian influenza (AI) is complex. The AI virus constantly evolves by mutation and re-assortment with
More informationModule 5: Introduction to Stochastic Epidemic Models with Inference
Module 5: Introduction to Stochastic Epidemic Models with Inference Instructors:, Dept. Mathematics, Stockholm University Ira Longini, Dept. Biostatistics, University of Florida Jonathan Sugimoto, Vaccine
More informationMathematics for Infectious Diseases; Deterministic Models: A Key
Manindra Kumar Srivastava *1 and Purnima Srivastava 2 ABSTRACT The occurrence of infectious diseases was the principle reason for the demise of the ancient India. The main infectious diseases were smallpox,
More informationEpidemic simulation of a foot and mouth disease outbreak in Minnesota
Rev. Sci. Tech. Off. Int. Epiz., 2015, 34 (3),... -... Epidemic simulation of a foot and mouth disease outbreak in Minnesota This paper (No. 18082015-00055-EN) has been peer-reviewed, accepted, edited,
More informationStudy population The study population comprised the general population of Senegal inhabitants aged 1 to 30 years.
Comparison of cost-effectiveness of preventive and reactive mass immunization campaigns against meningococcal meningitis in West Africa: a theoretical modeling analysis Parent du Chatelet I, Gessner B
More informationEU measures for surveillance and control of ASF in feral pigs
EU measures for surveillance and control of ASF in feral pigs 30 June 2014, Paris Francesco Berlingieri Unit G2 Animal Health Directorate-General for European Commission, Brussels This presentation does
More informationProgressive Control Pathway for Foot and Mouth Disease (PCP-FMD) Checklist Explanation. March 2013
Progressive Control Pathway for Foot and Mouth Disease (PCP-FMD) Checklist Explanation March 2013 Contents Instructions for filling out the PCP checklist:... 3 Checklist explanation PCP Stage 1... 4 Checklist
More informationProgressive Control Pathway for Foot and Mouth Disease (PCP-FMD) Checklist Explanation. March 2013
Progressive Control Pathway for Foot and Mouth Disease (PCP-FMD) Checklist Explanation March 2013 Contents Instructions for filling out the PCP checklist:... 3 Checklist explanation PCP Stage 1... 4 Checklist
More informationLUMPY SKIN DISEASE. Exotic diseases approaching EU: Alessandro Broglia Animal and Plant Health Unit European Food Safety Authority - EFSA
Exotic diseases approaching EU: LUMPY SKIN DISEASE EFSA Scientific Opinion, 2014 Alessandro Broglia Animal and Plant Health Unit European Food Safety Authority - EFSA JPC REMESA - 16-17 March 2015 CODEX
More informationFMD Report - Syria 6 th Regional FMD West Eurasia Roadmap Meeting - Almaty, Kazakhstan 28 to 30 April 2015
FMD Report - Syria 6 th Regional FMD West Eurasia Roadmap Meeting - Almaty, Kazakhstan 28 to 30 April 2015 Dr. Mazen Dib - Directorate Of Animal Health Syria 6th West Eurasia Roadmap Meeting Almaty, Kazakhstan
More informationModule 5: Introduction to Stochastic Epidemic Models with Inference
Module 5: Introduction to Stochastic Epidemic Models with Inference Instructors: Tom Britton, Dept. Mathematics, Stockholm University Ira Longini, Dept. Biostatistics, University of Florida Jonathan Sugimoto,
More informationEFSA projects on PPR, sheep pox, lumpy skin disease. Franck Berthe Animal and Plant Health Unit European Food Safety Authority - EFSA
EFSA projects on PPR, sheep pox, lumpy skin disease Franck Berthe Animal and Plant Health Unit European Food Safety Authority - EFSA 9th JPC REMESA Tunis, Tunisie - 03 and 04 November 2014 BACKGROUND PPR,
More information1-2 December 2015 Geneva, Switzerland. Anticipating emerging infectious disease epidemics
1-2 December 2015 Geneva, Switzerland Anticipating emerging infectious disease epidemics Session 1 Summary of the meeting Session 1: learning from the past (1) Preparedness (inter-epidemic period) is a
More informationRisk analysis of foodborne antimicrobial resistance (AMR) Suphachai Nuanualsuwan DVM, MPVM, PhD1
Risk analysis of foodborne antimicrobial resistance (AMR) Suphachai Nuanualsuwan 1 Introduction Antimicrobial resistance (AMR) is major global public health concern & food safety issue Risk Analysis :-
More informationRegional Training Needs
Regional Training Needs Gunel Ismayilova European Commission for the Control of Foot-and-Mouth Disease 7 th Regional FMD West Eurasia Roadmap Meeting, 6-8 April, 2016 Outline of this presentation 1) EuFMD
More informationThe New FMD Containment Zone Proposal and Vaccination. April 4, 2017, Pirenopolis, Brazil
The New FMD Containment Zone Proposal and Vaccination. April 4, 2017, Pirenopolis, Brazil Dr. Tom Smylie Senior Staff Veterinarian Canadian Food Inspection Agency 1 Topics for todays presentation. 1. Current
More informationSWINE PROGRAMS AT USDA APHIS VETERINARY SERVICES
SWINE PROGRAMS AT USDA APHIS VETERINARY SERVICES Dr. Don Rush Regional Epidemiologist USDA APHIS VS Raleigh, NC Veterinary Services programs consist of surveillance for foreign animal diseases (FADs),
More informationExotic diseases approaching EU EFSA mandates on PPR, sheep pox, lumpy skin disease
Exotic diseases approaching EU EFSA mandates on PPR, sheep pox, lumpy skin disease Frank Verdonck Animal and Plant Health Unit European Food Safety Authority - EFSA PAFF meeting -13-14 Jan 2015 BACKGROUND
More informationDevelopment of a stochastic, individual-based modeling framework for. within-unit transmission of highly infectious animal diseases
Development of a stochastic, individual-based modeling framework for within-unit transmission of highly infectious animal diseases A. Reeves 1, Marian Talbert 1, M.D. Salman 1, and A.E. Hill 1,2 1 Department
More informationErin Carson University of Virginia
THE QUANTIFICATION AND MANAGEMENT OF UNCERTAINTY IN SMALLPOX INTERVENTION MODELS Erin Carson University of Virginia 1 INTRODUCTION Uncertainty is an issue present throughout the field of modeling and simulation.
More informationFMD Summary Epidemiology Report Situation as at 10:00 Thursday 09 August, Day 6
FMD 2007. Summary Epidemiology Report Situation as at 10:00 Thursday 09 August, Day 6 Executive summary 1. Two confirmed cases and one highly probable case of Foot and Mouth Disease have been confirmed
More informationCHAPTER 2 THE EPIDEMIOLOGY OF FMD
Potential Impact of Foot-and-Mouth Disease in California 7 CHAPTER 2 THE EPIDEMIOLOGY OF FMD FMD virus is an aphtovirus within the picornaviridae family. The most important characteristics in the epidemiology
More informationBiostatistics and Computational Sciences. Introduction to mathematical epidemiology. 1. Biomedical context Thomas Smith September 2011
Biostatistics and Computational Sciences Introduction to mathematical epidemiology 1. Biomedical context Thomas Smith September 2011 Epidemiology The study of the distribution and determinants of healthrelated
More informationPoints to consider in the prevention, control and eradication of FMD Dr. Paul Sutmoller* and Dr. Simon Barteling**
1 Points to consider in the prevention, control and eradication of FMD Dr. Paul Sutmoller* and Dr. Simon Barteling** *Animal Health Consultant, Former Chief of Laboratories of the Panamerican FMD Center,
More informationStrategies for containing an emerging influenza pandemic in South East Asia 1
Strategies for containing an emerging influenza pandemic in South East Asia 1 Modeling pandemic spread and possible control plans of avian flu H5N1 BBSI, Nicole Kennerly, Shlomo Ta asan 1 Nature. 2005
More informationOIE Situation Report for Highly Pathogenic Avian Influenza
OIE Situation Report for Highly Pathogenic Avian Influenza Latest update: 31/05/2018 The epidemiology of avian influenza (AI) is complex. The AI virus constantly evolves by mutation and re-assortment with
More informationHealth technology Four strategies for the control of serogroup C meningococcal disease (CMD) were examined. These were:
Cost-effectiveness of immunization strategies for the control of serogroup C meningococcal disease De Wals P, Nguyen V H, Erickson L J, Guay M, Drapeau J, St-Laurent J Record Status This is a critical
More informationWhat s the Game Plan for Swine in Case of a Foreign Animal Disease Outbreak?
What s the Game Plan for Swine in Case of a Foreign Animal Disease Outbreak? Paul Kitching National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, 1015 Arlington Street, Winnipeg,
More informationThe role of dynamic modelling in drug abuse epidemiology
Offprint from Bulletin on Narcotics, vol. LIV, Nos 1 and 2, 2002 The role of dynamic modelling in drug abuse epidemiology C. ROSSI Department of Mathematics, University of Rome Tor Vergata, Rome ABSTRACT
More informationHPAI H5N8 in the United Kingdom
HPAI H5N8 in the United Kingdom PAFF Committee, 28th November 2014 Presented by: Jane Clark Outbreak History 14 November 2014: APHA Investigation into suspicion of avian notifiable disease on an indoor
More informationNational Foot and mouth Disease Control and Eradication Plan in Thailand
National Foot and mouth Disease Control and Eradication Plan in Thailand Bureau of Disease Control and Veterinary Services Department of Livestock Development The FMD control and eradication plan in Thailand
More informationPost-Vaccination Monitoring
Post-Vaccination Monitoring Samia Metwally, DVM, PhD Senior Animal Health Officer (Virologist) Animal Production and Health Division FAO of UN, Rome, Italy samia.metwally@fao.org Overview Why post-vaccination
More informationFMD Summary Epidemiology Report Situation as at 10:00 Thursday 09 August
FMD 2007. Summary Epidemiology Report Situation as at 10:00 Thursday 09 August Executive summary 1. Two confirmed cases and one highly probable case of Foot and Mouth Disease have been confirmed in Surrey
More informationA Flexible Automata Model for Disease Simulation
A Flexible Automata Model for Disease Simulation Shih Ching Fu and George Milne School of Computer Science and Software Engineering The University of Western Australia 35 Stirling Highway, Crawley, 6009,
More informationFarm Biosecurity: A Reassessment of Feasible Benefits in an Outbreak. Richard Horwitz
Farm Biosecurity: A Reassessment of Feasible Benefits in an Outbreak Richard Horwitz Committee on Foreign and Emerging Diseases United States Animal Health Association Annual Meeting Providence, RI October
More informationModelling HIV prevention: strengths and limitations of different modelling approaches
Modelling HIV prevention: strengths and limitations of different modelling approaches Leigh Johnson Centre for Infectious Disease Epidemiology and Research Background Models of HIV differ greatly in their
More informationHighly pathogenic avian influenza "The Epidemic" Regionalisation in the European Union
Highly pathogenic avian influenza "The 2016-2017 Epidemic" Regionalisation in the European Union Andrea Gavinelli, Head of Unit G3 Official controls and eradication of diseases in animals European Commission
More informationDownloaded from:
Sumner, T; Burgin, L; Gloster, J; Gubbins, S (213) Comparison of pre-emptive and reactive strategies to control an incursion of bluetongue virus serotype 1 to Great Britain by vaccination. Epidemiology
More informationOIE Situation Report for Avian Influenza
OIE Situation Report for Avian Influenza Latest update: 18/09/2017 This report presents an overview of current disease events reported to the OIE by its Members. The objective is to describe what is happening
More informationPRAGMATIST: A DECISION SUPPORT TOOL FOR FOOT AND MOUTH DISEASE VACCINE BANK MANAGERS
WHICH VACCINES ARE MOST IMPORTANT? PRAGMATIST: A DECISION SUPPORT TOOL FOR FOOT AND MOUTH DISEASE VACCINE BANK MANAGERS Melissa McLaws 1, Don King 2, Katie Hickey 1, Anna Ludi 2, Keith Sumption 1 European
More informationSelf-declaration of the recovery of freedom from highly pathogenic avian influenza in poultry by the Netherlands
Self-declaration of the recovery of freedom from highly pathogenic avian influenza in poultry by the Netherlands Declaration sent to the OIE on 12 July 2017 by Dr Christianne Bruschke, OIE Delegate for
More information