Welcome to the PulseNet/OutbreakNet West Coast Regional Meeting
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- Susanna Walsh
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1 Welcome to the PulseNet/OutbreakNet West Coast Regional Meeting February 5-7, 2019 Catamaran Hotel San Diego, CA 7:00 am 8:00 am Registration Tuesday, February 5, 2019 Joint Session 8:00 am - 8:30 am Welcome & Introductions DFWED Leadership Opening Remarks Session I: The Future is Here: PulseNet/OutbreakNet Transition to WGS Lessons Learned from an Outbreak (outbreak idea: E. coli O157:H7 in Romaine lettuce) CDC overview/national picture of outbreak Local perspectives (regional sub-clusters) Environmental assessment results Communication logistics between various agencies (lab/epi/feds) Lessons learned from British Columbia Open Discussion: Lessons learned & what can be improved? 10:00 am-10:30 am perform live demonstrations, provide information, or answer questions on their respective topic or program.
2 10:30 am 11:30 am Session II: The Future is Here: Managing New Workflows Managing New Workflows Perspectives from high volume vs low volume states Prioritization of isolates Interpreting and reporting WGS results o Understanding predictive resistance 11:30 am 12:00pm Open Discussion Moderator: State/EH 12:00 pm 1:30 pm Lunch On Your Own PulseNet Track 1:30pm 4:00pm PulseNet Updates at Federal/State Levels Adapting Workflows for WGS: Where Are We Now and What s to Come? Perspectives from Pilot labs (Q/A) - CO,USDA,WA Round Robin (Table Discussions): each laboratory present their overall laboratory workflows to larger group OR we can arrange room to have round tables and each laboratory discuss among the table their workflow and designate a person to provide summary of discussion to larger group. Planning committee can have a template for discussion items during this time: (#1. Does your workflow incorporate CIDTs?; #2. Does your workflow allow your laboratory to meet 7 working day TAT? #3, aside from $$, are there other issues preventing your lab for conducting real-time surveillance?; #4. How is your laboratory OutbreakNet and Environmental Health Track WGS Transition: Moving Forward 1. WGS Transition Overview 2. Prioritization for interviewing and updates from the WGS working groups 3. Local cluster detection demonstration and working group updates 2
3 prioritizing sequencing all Salmonella?. At end of this session, describe best practices from each group/table. Best practices for automation or making WGS efficient without automation, etc. 2:50pm-3:20pm perform live demonstrations, provide information, or answer questions on their respective topic or program. 3:20pm-4:05pm Panel discussion: Perspectives from high/low volume labs discuss how managing workflows. (USDA/FSIS) Low state? 3:05pm-3:35pm 3:35pm-4:15pm perform live demonstrations, provide information, or answer questions on their respective topic or program. How WGS transition effects communications a. Communications to the public and industry 4:15pm-4:30pm Open Discussion 4:05pm 4:30pm Discussion & Wrap Up 4:30 pm Adjourn for Day 1 4:30 pm Adjourn for Day 1 Breakout Sessions (Up to 3) 4:30 pm 5:30 pm 1. NCBI Pathogen Detection Pipeline 2. Foodborne and Diarrheal Diseases Message Mapping Guide Session 3. Applied Math Session 3
4 7:00 am 8:30 am Registration Wednesday, February 6, 2019 Sunrise Sessions (Up to 3) 7:30 am 8:15 am PulseNet Track 8:30 am 12:00 pm Guidance for Implementing & Conducting PN Surveillance Using WGS: What You Need to Know Jan 15 th date to transition. (we can likely fill in this as we get closer to the actual date to see if testing by pilot labs have been successful and/or if databases have undergone conversion at local/states Reporting Guidelines Cluster Detection Communication with Epis Reporting & Interpretation 1. What should states be adding to reports based on WGS results? What should be reported to providers? (USDA reports OutbreakNet and Environmental Health Track Outbreak Successes and Challenges: Part I Interesting and Local Outbreaks 1. Vibrio a. Discussion on WGS and Vibrio b. Crab/Oyster outbreaks c. Herring egg outbreaks d. Increase from CIDT/How to manage PCR panels with multiple positive results, false-positives [Open Discussion or Panel] 2. Listeria gluten-free outbreak Communications Session 1. What are people doing now? Challenges? 2. Cucumber outbreak and communication challenges 3. Botulism in salad at fair Moderator: 4
5 perform live demonstrations, provide information, or answer questions on their respective topic or program. 9:45am 10:15am perform live demonstrations, provide information, or answer questions on their respective topic or program. Outbreak Successes and Challenges: Part II Zoonotic Outbreaks Guinea Pig outbreak - Salmonella Enteritidis (CO) Traceback Salmonella Hadar in live poultry (CA) Hatchery investigation/environmental testing Link to current Salmonella Infantis (CDC) Zoonotic Outbreak Prevention Panel How states engage hatcheries, challenges with zoonotic prevention 12:00 pm 1:30 pm Lunch On Your Own 1:30 pm 4:30 pm Addressing QA/QC: Looking Through the Magnifying Glass Understanding QC metrics (Science/rational for metrics and developing thresholds Adapting reference methods to WGS: CAP/CLIA/ISO Considerations & Lessons Learned Updates from CDC PulseNet: Analysis certification timelines & addressing issues?? SeqSero: How NGS is replacing traditional serotyping-perspectives from states Addressing validations: experiences & sharing plans with BioNumerics. Good discussion about validating BioNumerics. Perspectives from state lab and CDC. 1:30pm 1:55pm 1:55pm-2:15pm Open Discussion Outbreak Successes and Challenges: Part III Environmental Assessments Panel 1. Salmonella infections linked to Kratom Panel a. Multiple serotypes b. Product testing c. non-regulated product 2. Marijuana edibles and food safety 5
6 Possibly done by Applied Math during a breakout session (4:30-5:30): Analysis Tools & BioNumerics conversion Q/A perform live demonstrations, provide information, or answer questions on their respective topic or program. 2:15pm-2:45pm perform live demonstrations, provide information, or answer questions on their respective topic or program. Foodborne Outbreak Investigation From an Environmental Health Perspective 1. CDC s Foodborne Outbreak National Environmental Assessment Reporting System: Improving Outbreak Investigation and Prevention (NEARS) (20 min) 2. Norovirus in a Las Vegas Resort (20 minutes) 3. Second speaker, TBD Exclusions a. E. coli in low socio-economic status daycare b. Hepatitis A i. In seafood from Mexico (AZ) ii. Food handlers and homeless population (San Diego) Retrospective Investigations Session 1. Listeria outbreaks 6
7 2. Salmonella Concord Open Discussion Moderators: 4:30 pm Adjourn for Day 2 4:30 pm Adjourn for Day 2 Breakout Sessions (Up to 3) 4:30 pm 5:30 pm 1. Cyclosporiasis 2. Consumer complaints workgroup (CO CoE?) 3. Learning From Lessons Learned Session 1. Hot washes best practices 2. FDA after-action portal demonstration 8:00 am -8:30 am Registration Thursday, February 7, 2019 Joint Session 8:30am 9:45am Session: The Future is Here: Where are we Now with CIDTs? - Panel Follow up on CIDT Forum? Panel discussion: What has changed for states since 2017 Meeting? New insights from states on use/implementation of CIDTs locally 9:45am 10:00am perform live demonstrations, provide information, or answer questions on their respective topic or program. ELC Panel Discussion ELC Update Perspectives from states (finding creative ways to supplement ELC funding) Discussion from state, regional, and high/low burden laboratories 7
8 Discussion from the epi perspective in high/low burden states Questions Wrap Up Outbreak (Lab/Epi/EH): ideas: Salmonella Newport in Mexican cheese Closing Remarks 12:00pm Evaluation and Adjourn Optional Trainings 1:00 pm 5:00 pm BioNumerics 7.6 for Laboratorians Instructor: CDC PulseNet Staff 1:00 pm 5:00 pm SEDRIC Instructor: CDC Staff 1:00 pm 5:00 pm Training #3 Instructor: 8
9 PROGRAM TABLES Tuesday, February 5, :00 am - 10:30 am & 3:00 pm - 3:30 pm Program Table and Representatives Table #1 NARMS and NST Table #2 CoEs and CIFOR Table #3 Illumina Table #4 FSIS Table #5 RRT Table #6 NORS and NEARS FoodNet, SEDRIC and Applied Math Wednesday, February 6, :00 am 10:30 am and 3:00 pm 3:30 pm Program Table and Representatives Table #1 NARMS and NST Table #2 CoEs and CIFOR Table #3 Illumina Table #4 FSIS Table #5 RRT Table #6 NORS and NEARS FoodNet, SEDRIC and Applied Math Hosted By the: Centers for Disease Control and Prevention, Division of Foodborne, Waterborne and Environmental Diseases United States Food and Drug Administration United Sates Department of Agriculture, Food Safety and Inspection Service Council of State and Territorial Epidemiologists National Environmental Health Association Association of Public Health Laboratories 9
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