RESoRba DEnTal Setting the Tone.

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1 REsorba Dental Setting the Tone. R E P A I R A N D R E G E N E R A T E

2 RESORBA DENTAL The new star ensemble in implantology

3 Masterpieces Tried and tested RESORBA quality enhanced and refined to meet the special demands of oral and maxillofacial surgery and implantology. Prophylaxis PARASORB HD Cone Collagen cones to reduce atrophy of the alveolar ridge (socket preservation) GENTA-COLL HD Cone Collagen cones to reduce atrophy of the alveolar ridge (socket preservation) with antibiotic protection for high-risk patients Regeneration RESODONT Absorbable collagen membrane for guided tissue regeneration (GTR, GBR) PARASORB Sterile collagen cavity and wound dressing for use in oral and maxillofacial surgery, local haemostatic agent PARASORB HD Sterile collagen cavity and wound dressing for use in maxillary surgery for osseous defects, local haemostatic agent GENTA-COLL resorb MKG Sterile collagen cavity and wound dressing for use in maxillary surgery for osseous defects, with antibiotic protection, local haemostatic agent Repair RESORBA Surgical suture material Absorbable and non-absorbable suture material for dental surgery

4 PERFECT HARMONY Collagens and suture materials for implantology and dental surgery Bone preservation and bone reconstruction are established elements of contemporary implantological care. RESORBA is there to assist, with high-end collagens specially designed for implantology - for the best possible functional and aesthetic results. Make the same high demands on your suture materials as you do on yourself! RESORBA offers you an extensive range of top-quality suture products.

5 The full score The right recommendation by RESORBA for any indication. Artikel PARASORB HD Cone GENTA-COLL HD Cone RESODONT 32 x 25 mm (8 cm 2 ) RESODONT 64 x 25 mm (16 cm 2 ) PARASORB 1,8 x 3,6 cm PARASORB 7,0 x 3,0 cm PARASORB HD 7,0 x 3,0 cm GENTA-COLL resorbmkg 2,5 x 2,5 cm SEIDE E 3/0 HR17 SUPRAMID 4/0 HRT18 PGA RESORBA 4/0 HRT18 RESOLON 6/0 DSM13 SEIDE E 4/0 HRT18 SUPOLENE 4/0 HRT18 SEIDE E 3/0 GR23 SUPRAMID 3/0 GR23 RESOLON 5/0 DSM16 SEIDE E 4/0 DSM16 SUPRAMID 4/0 DSM16 REF DK-1010 MK 10 RD 3503 RD 0703 DK-1836 DK-9001 DK-8001 MK PA SAF SAF Indication Alveolar care Socket preservation Augmentation Defect coverage GBR/GTR Haemostasis Interdental care Papilla reconstruction Periodontology Mucosa Mucosal graft Sinus floor elevation Wound tamponade Apicectomy Cystectomy

6 Repair Regeneration Prophylaxis CALLING THE TUNE PARASORB HD Cone GENTA-COLL HD Cone The first choice... for the care of extraction sockets. Particularly well suited for socket preservation in the sensitive anterior region.

7 Tooth extraction - the problem After an extraction, the alveolar socket does not always heal optimally without special care. This has consequences: The bone required for a stable and secure fit of an implant is only inadequately reformed. The alveolar ridge already starts to collapse at the extraction site and disappear after only a short time. A reconstruction of the alveolar ridge is necessary if an implant is to be positioned at a later time. Treatments are costly and time-consuming for the patients, as well as being painful and not completely without risk The 4-in-1 solution by RESORBA 1. Safe and rapid haemostasis - No risk of secondary bleeding - Stabilisation of the blood clot - Optionally comes with antibiotic protection for high-risk patients (e.g. smokers, diabetics, immunesuppressed patients) 2. Reduction of alveolar ridge atrophy - Stabilisation of the socket and maintenance of the sensitive vestibular lamella - Volume stability of the alveolar process - Improvement of the aesthetic and functional long-term results 3. Reliable bone regeneration - Already after a relatively short time, a stable bony implant site is formed - More easily predictable long-term success 4. High user and patient satisfaction - Simple and safe to use - Subsequent treatment steps are simplified - Higher patient comfort - Excellent value for money Literature on request

8 Repair Regeneration Prophylaxis The sensational drumbeat RESODONT The special barrier membrane The starting material is collagen of equine origin (originating from the horse) The starting materials for the biomatrices identical to RESORBA products for dura regeneration Naturally cross-linked, with no chemical additives Manufacturing processes following the strictest quality standards, derived from the manufacture of membranes for coverage of defects of the dura mater Maximum product safety and excellent biocompatibility Fully absorbable

9 Maxillary augmentation the problem After maxillary augmentation the following should be considered: Implants, lateral maxillary augmentation material or extraction alveoles need to be protected from the in-growth of soft tissue Augmentation material that is introduced needs to be secured and covered during guided tissue regeneration (GTR, GBR) Any accesses created as part of sinus lift operations need to be covered over again and the Schneiderian membrane protected from the sharp-edged particles of the augmentation material The solution by RESORBA Particularly easy to model Structurally stable, particularly when moist Usable on both sides thanks to special microstructure Reliable barrier function Completely absorbable, and therefore no need for re-entry surgery No fixing required Guide rail effect - Supports the regeneration of blood vessels (angioconductivity) and therefore the rapid integration into the surrounding tissue - Promotes bone growth (osteoconductivity) - Promotes the healing of wounds Secure haemostasis ph-stability and therefore reduced risk of inflammatory reactions RESODONT - tried and tested a thousand times over in everyday dental practice! The membrane is used in dental, oral and maxillofacial surgery principally for covering defects in the field of guided bone regeneration (GBR) and to secure augmentation material. Uses include local augmentation prior to or during the insertion of endosseous implants, the covering of the facial maxillary sinus wall and small perforations of the sinus mucosa in sinus lift operations and of alveolar cavities after extractions... Wound healing proceeded without infections or foreign body reactions; to date, the barrier function has always been adequate for undisturbed bony consolidation. If the membrane becomes exposed by dehiscences, immediate removal is not necessary because careful rinsing with disinfectants can achieve a secondary epithelialisation of the membrane without disturbing the underlying augmentation. Prof. Dr. Dr. J. Kleinheinz, Hospital and OPD for Oral, Maxillary and Facial Surgery University Hospital Münster. Literature on request

10 Repair Regeneration Prophylaxis THE TRIAD PARASORB PARASORB HD GENTA-COLL resorb MKG Haemostasis alone is not enough local haemostasis with the decisive advantage Compared to conventional haemostatics, such as oxidised cellulose or gelatine, PARASORB / PARASORB HD / GENTA-COLL resorb MKG offers a whole range of additional advantages: Structural stability Total resorption and therefore no need for re-entry surgery Potential docking site for proteins (growth factors etc.) Supports the regeneration of blood vessels (angioconductivity) and therefore the rapid integration into the surrounding tissue Guide rail effect for rapid bone regeneration (osteoconductivity) Promotes wound healing ph-stability and therefore reduced risk of inflammatory reactions Optional with antibiotic protection for high-risk patients (e.g. diabetes, immunosuppression, smokers): only GENTA-COLL resorb MKG

11 Orthodontic interventions the problem After an orthodontic procedure (e.g. cystectomy), a defect remains at the site of the intervention. This has consequences: Usually heavy bleeding Defect site fills with tissue fluid /blood Infection risk In-growth of soft tissue into the defect Bones are only inadequately reformed Functional and aesthetic impairments The 2-in-1 solution by RESORBA For an optimal treatment of wounds and defect sites immediately after operation: 1. Safe and rapid haemostasis No risk of secondary bleeding Stabilisation of the blood clot (acts as a placeholder) Optionally with antibiotic protection for risk patients (e.g. smokers, diabetics, immune-suppressed patients) and for potentially infectious environments (apicectomy, cysts) 2. Bone regeneration Guide rail effect - Promotion of new vessel formation angioconductivity - Promotion of bone growth osteoconductivity Placeholding function (especially PARASORB HD, GENTA-COLL resorb MKG) - No in-growth of soft tissue - Undisrupted bone regeneration Bleeding Time From Standardized Spleen Wound: min ,5 1,7 Collagen Collagen powder fleece 4,5 5,0 Gelatin sponge Oxidized cellulose Untreated control Collagen fleeces or powders have proved to be clearly more effective than gelatin sponges or cellulose. They are rapidly and completely absorbed by the body, with native Collagen additionally promoting granulation and epithelialization. Figure modified from a table from: Source: Silverstein ME, Facs, Chvapil M (1981) Experimental and clinical experiences with collagen fleece as a hemostatic agent Extent of Aggregation: Five minutes after contact with various wound dressings (platelet aggregation was determined from light transmittance): 18,0 100 F G H % 50 0 A 16 B 9 Various cellulose products C 18 D 18 E 19 Various gelatin products Various Collagen fleece products Collagen fleece products are significantly more effective at inducing platelet aggregation. Source: Stemberger A, Ascherl R, Scherer MA, Kaufer C, Pfeffer M, Blümel G (1992) Hämostyptika in der Chirurgie - in vitro Untersuchungen zur Stimulierung der Blutgerinnung sowie Festigkeit in Kombination mit Fibrinklebung Inc. Gebhardt C(ed) Fibrinklebung in der Allgemein- und Unfallchirurgie, Orthopädie, Kinder- und Thoraxchirurgie, Springer Verlag, Berlin, pp Literature on request

12 THE RIGHT CHORDS Prophylaxis Regeneration RESORBA Suture material for dental surgery Repair RESORBA Suture material RESORBA offers you a comprehensive range of suture products for dental surgery, which are of the highest possible quality. Your RESORBA medical device adviser will be happy to help! Ask us! The manufacture of customer-specific needle-suture combinations which always make particular demands on a company s efficiency is one of our specialities. We would be happy to make needle-suture combinations for you too from a certain minimum purchase quantity - according to your own personal concept.

13 Absorbable material Glycolon violet/undyed, monofilament, short-term absorbable For tissue adaptations where mechanical support is time-restricted Optimum tolerance in the body thanks to the chemical properties and refinements PGA Resoquick PGA Resorba undyed, braided, coated, short-term absorbable violet/undyed, braided, coated, medium-term absorbable Problem-free disintegration and elimination Caprolon violet/undyed, monofilament, long-term absorbable No encapsulations and tissue reactions during the disintegration process Resolon blue, monofilament, non-absorbable Non-absorbable material Supramid black/white, pseudo-monofilament, non-absorbable Long-term durability with simultaneous high biocompatibility Polyester Supolene green/white, braided, non-absorbable green, braided, coated, non-absorbable Optimum tolerance in the body thanks to the careful selection of starting materials and refining processes Problem-free removal Mopylen blue, monofilament, non-absorbable Resopren blue, monofilament, non-absorbable SILK E black, braided, non-absorbable Needles for dental surgery RESORBA Needles are optimally suited to any indication, surgical technique and tissue situation. Atraumatic thanks to seamless transition between needle and thread Special surface treatment and precision ground for minimum resistance when entering and gliding through the tissue Special types of needle available, also PREMIUM ground, of particularly high quality

14 How supplied and Pack Sizes REF Dimensions Units PZN MK 10 GENTA-COLL HD Cone Ø 1,2 cm, Height 1,6 cm 10 Cones DK-1010 PARASORB HD Cone Ø 1,2 cm, Height 1,6 cm 10 Cones RD 3503 RESODONT 32 x 25 mm (8 cm 2 ) 1 Membrane RD x 25 mm (16 cm 2 ) 1 Membrane DK-1836 PARASORB 1,8 x 3,6 cm 12 Sponges DK x 3 cm 5 Sponges DK-8001 PARASORB HD 7 x 3 cm 5 Sponges MK 25 GENTA-COLL resorb MKG 2,5 x 2,5 cm 5 Sponges GENTA-COLL HD Cone 1 collagen-gentamcin-cone contains 22,4 mg equine, native collagen fibrils, 16 mg Gentamicin sulfate, corresponding to 8,80 11,44 mg Gentamicin PARASORB HD Cone 1 collagen cone contains 22,4 mg equine, native collagen fibrils PARASORB 1cm² collagen sponge contains 2,8 mg equine, native collagen fibrils PARASORB HD 1cm² collagen sponge contains 5,6 mg equine, native collagen fibrils RESODONT 1cm² collagen membrane contains 2,8 mg equine, native collagen fibrils GENTA-COLL resorb MKG: 1 collagen-gentamicin-sponge of 2,5 x 2,5 x 0,5 cm contains 35 mg equine, native collagen fibrils, 25 mg Gentamicin sulfate, corresponding to 13,82 17,88 mg Gentamicin Resorba Wundversorgung GmbH & Co. KG Am Flachmoor Nürnberg Germany Tel / Fax / infomail@resorba.com /11 P1065 R E P A I R A N D R E G E N E R A T E

15 ORDER FORM Fax orders to: xxxxxxxxxxxx Distributor Customer address First name/second name Practice/Hospital Street Postcode/Town Telephone/Telefax Date/Signature GENTA-COLL HD Cone Collagen cones to reduce atrophy of the alveolar ridge (socket preservation), for use in maxillary surgery, with antibiotic protection, local haemostatic REF Dimensions Units Order Size/Unit MK10 Ø1,2 cm / Height 1,6 cm 10 PARASORB HD Cone Collagen cone to reduce atrophy of the alveolar ridge (socket preservation) for use in maxillary surgery, local haemostatic REF Dimensions Units Order Size/Unit DK-1010 Ø1,2 cm / Height 1,6 cm 10 GENTA-COLL MKG Sterile collagen cavity and wound dressing made of collagen for use in maxillary surgery, with antibiotic protection local haemostatic PARASORB Sterile collagen cavity and wound dressing for use in maxillary surgery, local haemostatic REF Dimensions Units Order Size/Unit REF Dimensions Units Order Size/Unit MK25 2,5 x 2,5 cm 5 DK ,8 x 3,6 cm 12 DK x 3 cm 5 RESODONT Absorbable collagen membrane for guided tissue regeneration (GBR, GTR) PARASORB HD Sterile collagen cavity and wound dressing made of highconcentrate collagen for use in maxillary surgery, local haemostatic REF Dimensions Units Order Size/Unit REF Dimensions Units Order Size/Unit RD x 25 mm (8 cm 2 ) 1 RD x 25 mm (16 cm 2 ) 1 DK x 3 cm 5 Suture material REF Order Size/Unit R E P A I R A N D R E G E N E R A T E

16 Resorba Wundversorgung GmbH & Co. KG Am Flachmoor Nürnberg Germany Tel / Fax / infomail@resorba.com /11 P1065 R E P A I R A N D R E G E N E R A T E

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