Congenital abnormalities. by the numbers

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1 AMERICAN ACADEMY OF DERMATOLOGY SKIN DISEASE BRIEFS Congenital abnormalities by the numbers Congenital abnormalities are among 24 skin diseases or disease categories examined in the Burden of Skin Disease report commissioned by the American Academy of Dermatology. The report examined prevalence, economic burdens, and mortality for skin disease in the U.S. using 2013 health care claims data drawn from insurance enrollment and claims databases and found that: 84.5 million Americans one in four saw a physician for skin disease; 50% of them are over 65 and have an average of 2.2 skin conditions. Skin disease cost the U.S. healthcare system $75 billion in medical, preventative, and prescription and non-prescription drug costs. One in three Americans with skin disease were seen by a dermatologist, who collaborate with other physicians throughout the health care system in caring for these patients. More than 961,000 Americans sought medical treatment in 2013 related to congenital abnormalities of the skin, a category that includes a number of diseases including hemangiomas, ichthyosis congenita, vascular hamartomas, and congenital ectodermal dysplasia. Congenital abnormalities: Were more prevalent in children than adults. Resulted in $205 million in medical costs. Mean a potential decrease in lifespan of 20 years. The charts that follow provide topline data on how congenital abnormalitis contribute to the overall burden of skin disease. The full report includes data on prescription and non-prescription drug costs, and how age and insurance status and provider relate to the burden associated with congenital abnormalities and skin disease broadly. To purchase the report visit

2 Prevalance NUMBER OF CARED-FOR INDIVIDUALS 30,000,000 25,000,000 20,000,000 15,000,000 10,000,000 5,000, ,089 NON-CANCEROUS SKIN GROWTHS* VIRAL AND FUNGAL DISEASES WOUNDS AND BURNS CONTACT DERMATITIS * This category is clinically broad in nature and includes, among other diseases: benign neoplasms, melanocytic nevi (unspecified), pilar cysts, pilonidal cysts (with or without abscess), scars and fibrosis, etc. ABNORMALITY PATIENTS BY AGE* 40.0% 35.0% 34.9% 30.0% 25.0% 20.0% 22.2% 22.0% 20.8% 15.0% 0.34% 10.0% 5.0% 0.0% *Percentage of congenital aabnormality patients seen by a physician by age group.

3 Cost TOTAL MEDICAL COST* (IN MILLIONS USD) $9,000 $8,000 $7,000 $6,000 $5,000 $4,000 $3,000 $8,135 $7,015 $6,398 $6,052 $5,442 $2,000 $1,000 $0 $205 NON-CANCEROUS SKIN GROWTHS** WOUNDS AND BURNS SKIN CANCER*** ULCERS * In millions of dollars compared to most costly skin diseases. * *This category is clinically broad in nature and includes, among other diseases: benign neoplasms, melanocytic nevi (unspecified), pilar cysts, pilonidal cysts (with or without abscess), scars and fibrosis, etc. *** Represents combined data for melanoma and nonmelanoma skin cancer. COST OF SKIN DISEASE PER AFFECTED PERSON* $3, $3, $2, $2, $1, $1, $ $0.00 $ LYMPHOMA SKIN CANCER** ULCERS CONNECTIVE TISSUE DISEASES BULLOUS DISEASES *Compared with most costly skin diseases. ** Represents combined data for melanoma and nonmelanoma skin cancer.

4 Life Impact MORTALITY* 5,000 4,500 NUMBER OF DEATHS IN ,000 3,500 3,000 2,500 2,000 1,500 1, , Y 3, Y 2, Y 1, Y 1, Y Y SKIN CANCER** WOUNDS AND BURNS ULCERS CONNECTIVE TISSUE DISEASES * Provides the total number of deaths and average age at death from congenital abnormalities compared with other skin diseases with highest mortality. ** Represents combined data for melanoma and nonmelanoma skin cancer. YEARS OF POTENTIAL LIFE LOST* TOTAL SKIN DISEASES ALL CAUSES OF DEATH ALL CAUSES OF DEATH TOTAL SKIN DISEASES WOUNDS AND BURNS CONNECTIVE TISSUE DISEASES 7.9 YEARS * Estimate/projected number of life years lost due to congenital abnormalities compared to top skin diseases leading to early death; Projected based on prototypical lifespan of 75 years.

5 Life Impact (cont d) LOST PRODUCTIVITY (OPPORTUNITY COST)* $2,500 (IN MILLIONS USD) $2,000 $1,500 $1,000 $1,924 $1,570 $1,413 $940 $699 $500 $0 $34 NON-CANCEROUS WOUNDS SKIN GROWTHS** AND BURNS VIRAL AND FUNGAL DISEASE CONTACT DERMATITIS * Time lost by patients and/or caregivers multiplied by average wages in 2013 ($192/day); In millions of dollars compared with skin diseases leading to the most loss of productivity. * *This category is clinically broad in nature and includes, among other diseases: benign neoplasms, melanocytic nevi (unspecified), pilar cysts, pilonidal cysts (with or without abscess), scars and fibrosis, etc.

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