Geographic & Socioeconomic Predictors of Perforated Appendicitis: A National Canadian Cohort Study
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1 Geographic & Socioeconomic Predictors of Perforated Appendicitis: A National Canadian Cohort Study Gilly Akhtar-Danesh, Aristithes Doumouras, Dennis Hong, Helene Flageole
2 Disclosure No conflicts of interest to declare
3 Background Appendicitis is the most common surgical emergency in children Outcomes are dependent on disease severity Perforated appendicitis associated with Increased morbidity Longer length of stay
4 Background Some studies suggest SES predicts perforation rates Effect should dissipate in a universal healthcare system Rurality increases perforation risk in adults Exact spatial patterns have not been delineated
5 Objective To determine whether geography and socioeconomic status predict perforated appendicitis in children within a large, universal healthcare system.
6 Methods Population-based retrospective cohort Canadian children with appendicitis from Outcomes Perforation rates Complications
7 Methods Predictors Patient factors Surgeon and hospital specialization SES Distance from treating hospital Spatial analysis identified neighbourhoods with average vs. high perforation rates
8 Results 43,055 children with appendicitis identified Overall perforation rate 31.5% Higher perforation rates Females Younger children Rural neighbourhoods & >125 km distance
9 Results SES not associated with perforation risk >750,000 children living in high perforation clusters Complication rates associated with Use of laparoscopy Perforation Treatment at a pediatric hospital
10 Results
11 Discussion Understanding the determinants of surgical outcomes is imperative to improving outcomes In the multi-payer healthcare system, access affected by Race SES Insurance status Education
12 Discussion In single-payer system, SES does not affect outcomes Studies across cancer and surgical care However, rurality influences access to care in adults
13 Discussion This study found a clear inequity in outcomes based solely on patient location Independent of other factors >750,000 Canadian children at increased risk of complications from appendicitis No benefit offered by treatment at a pediatric hospital
14 Conclusion SES has no impact on appendiceal perforation rates in a universal healthcare system Geography is an important determinant of outcomes Despite universal healthcare, inequities exist in access to timely surgical care
15 Conclusion In a universal healthcare system, appendiceal perforation is a spatial phenomenon Distance from treating hospital and rurality increase perforation risk Disparities exist in access to timely surgical care in large countries with universal healthcare systems
16 References Beres A, Al-Abbad S, Puligandla PS. Appendicitis in northern aboriginal children: does delay in definitive treatment affect outcome? J Pediatr Surg. 2010;45(5): doi: /j.jpedsurg Borenstein SH, To T, Wajja A, Langer JC. Effect of subspecialty training and volume on outcome after pediatric inguinal hernia repair. J Pediatr Surg. 2005;40(1): doi: /j.jpedsurg Chen K, Cheung K, Sosa JA. Surgeon volume trumps specialty: outcomes from 3596 pediatric cholecystectomies. J Pediatr Surg. 2012;47(4): doi: /j.jpedsurg Cheong LHA, Emil S. Determinants of appendicitis outcomes in Canadian children. J Pediatr Surg. 2014;49(5): doi: /j.jpedsurg Cheong LHA, Emil S. Outcomes of pediatric appendicitis: an international comparison of the United States and Canada. JAMA Surg. 2014;149(1): doi: /jamasurg Cheong LHA, Emil S, DJ S, P H, SK P, A K. Outcomes of Pediatric Appendicitis. JAMA Surg. 2014;149(1):50. doi: /jamasurg Gani F, Hundt J, Daniel M, Efron JE, Makary MA, Pawlik TM. Variations in hospitals costs for surgical procedures: inefficient care or sick patients? Am J Surg. 2017;213(1):1-9. doi: /j.amjsurg Juurlink D, Preyra C, Croxford R, et al. Canadian Institute for Health Information Discharge Abstract Database: A Validation Study. Toronto; Maddison AR, Asada Y, Urquhart R. Inequity in access to cancer care: a review of the Canadian literature. Cancer Causes Control. 2011;22(3): doi: /s Masoomi H, Mills S, Dolich MO, et al. Comparison of Outcomes of Laparoscopic Versus Open Appendectomy in Children: Data from The Nationwide Inpatient Sample (NIS), World J Surg. 2012;36(3): doi: /s McAteer JP, LaRiviere CA, Oldham KT, Goldin AB. Shifts towards pediatric specialists in the treatment of appendicitis and pyloric stenosis: trends and outcomes. J Pediatr Surg. 2014;49(1):123-7; discussion doi: /j.jpedsurg Paquette IM, Zuckerman R, Finlayson SRG. Perforated appendicitis among rural and urban patients: implications of access to care. Ann Surg. 2011;253(3): doi: /sla.0b013e d68. Pittman-Waller VA, Myers JG, Stewart RM, et al. Appendicitis: why so complicated? Analysis of 5755 consecutive appendectomies. Am Surg. 2000;66(6): Ponsky TA, Huang ZJ, Kittle K, et al. Hospital- and Patient-Level Characteristics and the Risk of Appendiceal Rupture and Negative Appendectomy in Children. JAMA. 2004;292(16):1977. doi: /jama To T, Langer JC. Does access to care affect outcomes of appendicitis in children? - a population-based cohort study. BMC Health Serv Res. 2010;10(1):250. doi: / Zwintscher NP, Steele SR, Martin MJ, Newton CR. The effect of race on outcomes for appendicitis in children: a nationwide analysis. Am J Surg. 2014;207(5):748-53; discussion 753. doi: /j.amjsurg
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