Treatment of Lumbar Spinal Stenosis with Diabetes Mellitus

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1 Abstract Treatment of Lumbar Spinal Stenosis with Diabetes Mellitus Sang Wook Bae, M.D., Ho Yoon Kwak, M.D., Baik Yong Song, M.D., Nam Hong Choi, M.D., Ho Jun Kim, M.D. Department of Orthopedic Surgery, Nowon Eulji Hospital, Eulji University School of Medicine Study Design : This retrograde study was designed to compare the clinical features and postoperative clinical results between diabetic and non-diabetic patients who had been performed decompression and arthrodesis with instrumentation. Summary of Literature Review : There are controversies in the treatment results of diabetic patients. Objective : To identify poor results in the patients of lumbar spinal stenosis accompanied diabetes mellitus and to find out variables influencing postoperative results among diabetics. Materials and Methods : We analyzed 27 diabetic patients and sex, age-matched 27 non-diabetic patients who were diagnosed as lumbar spinal stenosis and operated from April, 1995 to December, In all patients, duration of symtoms, sensory and motor deficits, co-morbidity, level of operations were investigated and in diabetics, duration of diabetes, amount of insulin administered before operation and presence of diabetic neuropathy were included. Clinical results, postoperative complications were compared between diabetics and non-diabetics. Results : Considerable improvement was reported by 19(71%) in diabetic group and 21(78%) in non-diabetic group. Complication rate such as of infection and delayed wound healing was not higher in diabetic group than non-diabetic group. Duration of diabetes and amount of insulin before operation did not affected the result of operations. Conclusion : The outcome of surgery was similary successful in the two groups. Key Words : Lumbar spinal stenosis, Diabetes mellitus, Decompression and arthrodesis Address reprint requests to Sang Wook Bae, M.D. Department of Orthopaedic Surgery, Nowon Eulji Hospital #280-1 Hagye-dong, Nowon-ku, Seoul, Korea Tel : , 8260 Fax : , bsw2402@eulji.or.kr

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3 Table 1. Clinical Features Diabetic Non-diabetic Symptom duration(yr) < 1 14(52%) 13(48%) 1-3 7(26%) 9(33%) > 3 6(22%) 5(19%) Claudication(m) < (48%) 13(48%) (30%) 7(26%) > 300 3(11%) 3(11%) Neurologic deficit sensory 13(48%) 14(52%) motor 11(41%) 10(37%) Co-morbidity 0-2 8(30%) 13(48%) (52%) 10(37%) > 6 5(18%) 4(15%) Follow-up(yr) 1-2 9(33%) 8(30%) (41%) 10(37%) > 3 7(26%) 9(33%)

4 Table 2. Radiographic fusion Lenke grade Diabetic Non-diabetic A 13(48%) 15(55%) B 8(30%) 8(30%) C 4(15%) 3(11%) D 2(7%) 1(4%) Total 27(100%) 27(100%) Table 3. Clinical Results Diabetic Non-diabetic Excellent 4(15%) 5(19%) Good 15(56%) 16(59%) Fair 6(22%) 5(18%) Poor 2(7%) 1(4%) Total 27(100%) 27(100%) Table 4. Relationship of clinical result and duration of diabetes < >20(Yrs) Excellent Good Fair Poor Total Table 5. Postoperative Complications Diabetic Non-diabetic Meralgia paresthetica 3 2 Paralytic ileus 2 2 Urination difficulty 1 2 Infection superficial 1 1 deep

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6 13) Cinnoti G, Postacchini F and Weinstein JN : L u m b a r spinal stenosis and diabetes. Outcome of surgical decom - pression. J Bone Joint Surg, 76-B: , ) Fujimoto WY, Bergstrom RW, Newell-Morris L and Leonetti DL : Nature and nurture in the etiology of type 2 diabetes mellitus in Japanese Americans. Diabetes Metab Rev, 5:607, ) Hirsh LF : Diabetic polyradiculopathy simulating lumbar disc disease. Report of four cases. J Neurosurg, 60: , ) Katz JN, Lipson SJ, Larson MG, McInnes JM, Fossel AH and Liang MH : The outcome of decompressive laminectomy for degenerative lumbar stenosis. J Bone Joint Surg, 73-A: , ) Lee JH and McCarty R : Pain threshold in diabetic rats:effects of good versus poor diabetic control. Pain, 50: , ) Lenke LG, Bridwell KH, Bullis D, Betz RR, Baldus C and Schoenecker PL : Results of in situ fusion for isthmic spondylolisthesis. J of Spinal Disorders, 5: , stenosis. Instructional Course Lecture, , ) Park YS, Lee HK, Koh CS et al : Community-based epi - demiologic study on diabetes mellitus in Younchon County in Korea(Presented at IDF-WPR Congress 1993) 12) Sekigawa A, Tominaga M, Takahashi K et al : P r e v a - lence of diabetes and impaired glucose tolerance in Funa - gata area Japan. Diabetes Care, 16:570, ) Simpson JM, Silveri CP, Balderston RA, Simeone FA, and An HS : The results of operation on the lumbar spine in patients who have diabetes mellitus. J Bone Jonit Surg, 75-A: , ) Sullivan JF : The neuropathies of diabetes. Neurology (Minneap), 8: , ) Wakasugi M, Wakao R, Tawata M, Gan N, Koizumi K REFERENCES 11) : 16) Watanabe R and Parke WW : Vascular and neural., 5-1:9-17, ) Bastron JA and Thomas JE : Diabetic polyradiculopa - thy. Clinical and electromyographic findings in 105 patients. Mayo Clin Proc, 56: , ) Linn BS, Linn MW and Gurel L : Cumulative illness rating scale. J Am Geriatric Society, 16-5: , ) Martinelli TA and Wiesel SW : Epidemiology of spinal and Onaya T : BMD measured by dual energy x-ray absorptiometry in patients with non-insulin-dependent diabetes mellitus. Bone, 14(1):29-33, pathology of lumbosacral spinal stenosis. J Neurosurg, 64:64-70, ) Watkins PJ : Natural history of the diabetic neuropathies. Quarterly J of Med. New Series, : ,

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