Title: Effectiveness of the Austrian Disease Management Program for diabetes: a cohort study based on health insurance provider's routine data
|
|
- Adelia Pitts
- 6 years ago
- Views:
Transcription
1 Author's response to reviews Title: Effectiveness of the Austrian Disease Management Program for diabetes: a cohort study based on health insurance provider's routine data Authors: Herwig Ostermann (herwig.ostermann@umit.at) Victoria Hoess (victoria.hoess@umit.at) Micheal Mueller (michael.mueller@svagw.at) Version: 2 Date: 13 March 2012 Author's response to reviews: see over
2 Comments to Reviewer 1 (Renee Stark) First of all, the authors would like to thank the reviewer for her valuable comments. In fact, we have tried to incorporate the reviewer s suggestions whenever possible. Study population 1. The authors do not clarify which type of diabetes they are studying. I assume that the authors are intending to assess patients with type 2 diabetes (which is also the only type of diabetes included in the DMP program in Styria according to internet information) but the authors do not define this population in their paper this must be clarified in all parts of the paper. The authors clarified that only type 2 diabetics were studied. In addition to changes throughout the text, the authors changed the title of the manuscript, too. Study population: 2. Furthermore, if the authors are only studying type 2 diabetics, although the diagnosis is mostly certain in the DMP population (because the physicians have included the patients in the DMP program), this is not true for the controls and the authors do not describe any steps taken to exclude patients with Type 1 diabetes out of the control group. Having Type 1 diabetics in the control group leads to biased results since this group of patients will likely have had the diabetes for a longer period of time, may require closer monitoring for their blood glucose control and insulin and maybe more likely to have complications and complications requiring hospitalisation. If distinction between Type 1 and Type 2 diabetics is not possible according to the data (are some diagnoses available from the hospital admission and discharge data?), the authors should consider performing separate analyses according to medication intake comparing only patients taking oral antidiabetics or oral anti-diabetics with insulin or by excluding patients younger than 40 years of age and only taking insulin from the controls. Another strategy could be to adjust all analyses for the types of medication taken for treatment of diabetes and then discuss differences between the groups also regarding the possibility that type 1 diabetics could be included in the controls. If type 1 diabetics are left in the control group the authors should discuss what proportion of controls are likely to be type 1 and should also discuss their effects on the calculated costs. As the authors did not have access to inpatient diagnosis data, the authors adopted the reviewer s suggestion and performed separate analyses according to medication intake. Analyses: 1. The authors should support the use of the t-test to analyse utilisation and cost data. Are cost data and utilisation data normally distributed in their sample? It could be expected that both would have a skewed distribution. If regression analyses are considered by the authors, they should consider if using a gamma distribution would be appropriate in their cost analyses. The authors reconsidered the data analysis performed due to the reviewers comments and included tests for normal distribution for metric variables. As the reviewer expected most variables turned out to have a skewed distribution. As the metric variables assessed and in particular cost as well as overall utilisation data did not show an extremely skewed distribution, the authors considered that the application of non-parametric tests (Mann-Whitney U-Test) as being an appropriate procedure.
3 Analyses: 2. Furthermore, since the study is not randomised, one should adjust at least for age and sex especially if there are differences in age between the groups using simple testing. The authors did adjust for sex and age as suggested by the reviewer and indicated the adjustment in the section in data analysis. Results: 1. Could some differences between the groups regarding testing for HbA1c and lipid levels be due to the fact that levels were tested in the hospital? According to hospitalization rates of the revised study population, the share of patients hospitalized in 2009 was almost equal (35% of DMP patients vs. 35.6% of non-participating patients). Even though some differences in the average number of stays of hospitalized patients persist (1.8 stays for DMP patients vs. 2.2 stays for nonparticipating patients), these differences are unlikely to contribute to the observed differences in HbA1c and lipid level testing to a major extent. Results: 2. The authors should also discuss whether the diabetes of patients in the control group could be cared for in out-patient clinics in the hospital (0 hospital days as discussed in reference 22 of the paper) and whether this would be evident in their data set. The authors should also discuss what the effect of receiving treatment or primary care for diabetes in hospitals would have on the costs (increase or decrease costs). When analyzing hospitalization rates, the authors only included inpatient stays due to the fact, that data on stays in outpatient clinics in the hospital are only systematically reported to the insurer in case of 0-day stays but not in the case of regular services provided in hospitals outpatient clinics. The latter services are predominantly remunerated as lump-sum payments out of the centrally pooled hospital payment funds; therefore reporting of these cases to the insurance institution is not required due to financial reasons. Overall, cost data on different outpatient services provided in Austrian hospital clinics is very rare and only exists for some selected procedures such as MRT or mammography screenings. However, even for this procedures, evidence is not uniform in terms of its direction, resulting in cost advantages for services provided by specialists in one federal state to cost advantages for outpatient clinics in another state (for further evidence see: Rechnungshof (2011): Finanzierung und Kosten von Leistungen in Spitalsambulanzen und Ordinationen. Wien). Due to this lacking data for the Austrian context, the authors decided not to discuss potential cost effects of shifting health service delivery from medical specialists to outpatient clinics in hospitals. However, more information was provided on the exclusion of 0-day stays when presenting the outcome measures for hospitalization rates in the methods section of the manuscript. Minor revisions: Under Methods and Population, line 4: please clarify what insured by an author social insurance institution means. The authors changed this passage into: insured by another social insurance institution
4 Comments to Reviewer 2 (Soeren Mattke) First of all, the authors would like to thank the reviewer for his critical comments. In fact, the authors have tried to expand the design of the study and included data on costs and utilization before the start of the DMP in order to meet the reviewer s critique. Thank you for the opportunity to review your manuscript. Before I go into details, pls allow me to verify that my understanding of your approach is correct. You use data for the first year of the DMP and compare utilization and cost for diabetics who are enrolled to those who are not. If that is correct, your design that not allow drawing valid conclusions. While you state that the overall population is quite homogenous, it is still entirely possible that the enrollees are systematically different from the non-enrollees and that those underlying differences, rather than the DMP, account for the differences in cost and utilization. In fact, you do find differences in age. But without data on cost/utilization before program start, clinical severity and comorbidities, your results are impossible to interpret. If I misunderstood, pls clarify your approach and I'm happy to review again. In the original design, the authors used 2009 data in order to compare costs as well as out- und inpatient services utilization of type 2 diabetics enrolled in the Austrian disease management program to those patients receiving regular treatment. As the DMP started in 2007, participating patients were on average enrolled 1 year prior to the study period ( ). However the authors agree with the reviewer s comment that the two populations compared may be different in terms of specific characteristics, which might also cause overall differences in costs as well as utilization. Hence, the authors have somewhat changed the study design for the revised manuscript: First, the authors did control for sex and age in the control group. Second, the authors also integrated data on utilization and costs for both study groups for 2006 providing overall information on cost/utilization before the program started as shown in the revised table 6. Even though the authors did not gain access to the full set of the insurers patients records for 2006, which would have been necessary in order to provide 2006 data for tables 2-5, table 6 now provides useful information on the baseline characteristics on costs as well as utilization for both study groups, indicating different patterns of costs of outpatient care for both study groups before the start of the DMP, but also different developments in terms of the numbers of outpatient services received as well as average days spent in hospital in particular. Concerning the reviewer s suggestion on integrating clinical severity of the disease as well as comorbidities at baseline, the authors were not able to gain any information on these parameters as clinical reports including data on diagnoses are held by hospitals and integrating these data with insurer s records what raise severe data protection concerns. As far as diagnoses data for outpatient care is concerned it has to be noted that Austrian GPs and specialists are not obliged to report data on diagnoses to insurers.
5 Comments to Reviewer 3 (Ulrike Rothe) First of all, the authors would like to thank the reviewer for her valuable comments. In fact, we have tried to incorporate the reviewer s suggestions whenever possible. 1) Nevertheless the focus of better quality of care in the evaluation study is limited to the process quality. Therefore, please add in the chapter Outcome measures in the first sentence the word process prior the word quality. You could not observe the outcome quality because of the health insurance database, could you? Furthermore the Austrian DMP reached only about 2,5% of all medication treated diabetic patients in the region. This is contradictory to the statement: As for other the Austrian diabetes DMP incorporates a population-based strategy.. Why is the participation rate not higher, although there are quite high incentives for physicians (a lump sum payment of 100 p.a. and an extra reimbursement of 55)? Can you identify reasons for that? The authors added the word process as the reviewer suggested. Moreover the authors discussed low participation rates of the Austrian diabetes DMP in the discussion section focusing on currently dysfunctional financial incentives for insurers. 2) Another question: Are the GP s and the specialists working together (integrated care)? Currently, participating physicians, that are most commonly either GPs or specialists for internal medicine, receive a lump sum payment, which also includes compensation for the coordination of care amongst other specialists as well as outpatient clinics and inpatient care. However, models of integrated care in terms of established cooperation amongst different providers of outpatient and inpatient care along with an adequate financing scheme have not been developed yet. The authors have included a corresponding passage in the article when presenting the Austrian diabetes DMP. 3) What s about the metabolic syndrome? You wrote only: achievement of optimal blood sugar management., there are no results concerning the blood pressure, are there? In fact, the Austrian diabetes does not explicitly mention the metabolic syndrome. Due to the fact, that we only gained permission to the insurer s records on outpatient care consisting of services provided as well as its corresponding fees, we did not have an information on blood pressure or any other parameter indicating outcome quality. 4) Please, avoid redundance in the tables. Therefore, please, rename the table 3 into table 2a (with significant results) and table 2 into table 2b and remove all redundant results (in table 2b now only the non-significant results). We integrated tables 2 and 3 into one new table (table 2).
6 5) I miss some very important references to show the possibility of improvement of outcome quality of care by diabetes disease management statewide, for example, published in Diabetes Care 2008; 31 (5): Please, add this reference, for example, in the section discussion page 10, line 7. Thank you very much for this very interesting and also relevant source. In fact, we added this paper to our reference list and also cited the authors in the discussion section. 6) Last, you should conclude according to the new reference whether to adopt disease management as a standard benefit or not this depends on the kind of the disease management program! The better way is the chronic care model by Wagner et al. for multi-morbid patients in an integrated care setting. The last sentence should conclude with: the effects of the Austrian diabetes DMP and with intermediate outcomes. Thank you also for this comments, which have been included in the revised conclusion section.
had non-continuous enrolment in Medicare Part A or Part B during the year following initial admission;
Effectiveness and cost-effectiveness of implantable cardioverter defibrillators in the treatment of ventricular arrhythmias among Medicare beneficiaries Weiss J P, Saynina O, McDonald K M, McClellan M
More informationThe Konstanz Study - A German Consumer Reports Study (TKS)
The Konstanz Study - A German Consumer Reports Study (TKS) Breyer, F., Heinzel, R. & Klein, Th. (1997). Kosten und Nutzen ambulanter Psychoanalyse in Deutschalnd (Cost and benefit of outpatient analytical
More informationTitle: Identifying work ability promoting factors for home care aides and assistant nurses
Author's response to reviews Title: Identifying work ability promoting factors for home care aides and assistant nurses Authors: Agneta Larsson (agneta.larsson@ltu.se) Lena Karlqvist (lena.karlqvist@ltu.se)
More informationTitle: Prevalence of sexual, physical and emotional abuse in the Norwegian Mother and Child Cohort Study
Author's response to reviews Title: Prevalence of sexual, physical and emotional abuse in the Norwegian Mother and Child Cohort Study Authors: Marie F Sorbo (marie.flem.sorbo@ntnu.no) Hilde Grimstad (hilde.grimstad@ntnu.no)
More informationChapter 6: Healthcare Expenditures for Persons with CKD
Chapter 6: Healthcare Expenditures for Persons with CKD In this 2017 Annual Data Report (ADR), we introduce information from the Optum Clinformatics DataMart for persons with Medicare Advantage and commercial
More informationHealth technology Two prophylaxis schemes against organ rejection in renal transplantation were compared in the study:
An economic and quality-of-life assessment of basiliximab vs antithymocyte globulin immunoprophylaxis in renal transplantation Polsky D, Weinfurt K P, Kaplan B, Kim J, Fastenau J, Schulman K A Record Status
More informationSandwell & West Birmingham integrated community care diabetes model (DICE) the future of diabetes services?
Sandwell & West Birmingham integrated community care diabetes model (DICE) the future of diabetes services? Dr PARIJAT DE DUK Clinical Champion Clinical Lead for Diabetes & Endocrinology, Sandwell & West
More informationAuthor's response to reviews
Author's response to reviews Title: Morbidity and doctor characteristics only partly explain the substantial healthcare expenditures of frequent attenders - A record linkage study between patient data
More informationGOVERNING BODY REPORT
GOVERNING BODY REPORT DATE OF MEETING: 20th September 2012 TITLE OF REPORT: KEY MESSAGES: NHS West Cheshire Clinical Commissioning Group has identified heart disease as one of its six strategic clinical
More informationWORKING P A P E R. Estimating the Impact of Improving Asthma Treatment. A Review and Synthesis of the Literature
WORKING P A P E R Estimating the Impact of Improving Asthma Treatment A Review and Synthesis of the Literature SOEREN MATTKE, FRANCISCO MARTORELL, PRIYA SHARMA, LINDSEY K. MORSE, NICOLE LURIE, MARIELANA
More informationTitle: Exposure of bakery and pastry apprentices to airborne flour dust using PM2.5 and PM10 personal samplers
Author's response to reviews Title: Exposure of bakery and pastry apprentices to airborne flour dust using PM2.5 and PM10 personal samplers Authors: Estelle Mounier-Geyssant (estellemounier@yahoo.fr) Jean-Francois
More informationExcellence comprises openness National Open Access Strategy and OA at the SNSF. Dr. Tobias Philipp
Excellence comprises openness National Open Access Strategy and OA at the Dr. Tobias Philipp Swiss political system and actors Federal and cantonal competencies for higher education institutes: Limited
More informationTitle:Systematic review and meta-analysis of the effect of increased vegetable and fruit consumption on body weight and energy intake
Author's response to reviews Title:Systematic review and meta-analysis of the effect of increased vegetable and fruit consumption on body weight and energy intake Authors: Oliver T Mytton (otm21@medschl.cam.ac.uk)
More informationExamples of Nordic collaborations: benefits and challenges
Examples of Nordic collaborations: benefits and challenges There are numerous well working ongoing Nordic research collaborations, and some Nordic organizations that have a long track record of systematic
More informationTitle: Selection effects may account for better outcomes of the German Disease Management Program for type 2 diabetes
Author's response to reviews Title: Selection effects may account for better outcomes of the German Disease Management Program for type 2 diabetes Authors: Ingmar Schäfer (in.schaefer@uke.uni-hamburg.de)
More informationTitle: Protocol-based management of older adults with hip fractures in Delhi, India: a feasibility study
Reviewer s report Title: Protocol-based management of older adults with hip fractures in Delhi, India: a feasibility study Version: 0 Date: 16 Nov 2015 Reviewer: Cristin Ryan Reviewer's report: This paper
More informationCase complexity adjustment and Mental health outcomes: Conceptual issues
Australian Mental Health Outcomes and Classification Network Sharing Information to Improve Outcomes An Australian Government funded initiative Case complexity adjustment and Mental health outcomes: Conceptual
More informationTitle: Elevated depressive symptoms in metabolic syndrome in a general population of Japanese men: a cross-sectional study
Author's response to reviews Title: Elevated depressive symptoms in metabolic syndrome in a general population of Japanese men: a cross-sectional study Authors: Atsuko Sekita (atsekita@med.kyushu-u.ac.jp)
More informationStandard emergency department care vs. admission to an observation unit for low-risk chest pain patients. A two-phase prospective cohort study
Standard emergency department care vs. admission to an observation unit for low-risk chest pain patients A. STUDY PURPOSE AND RATIONALE Rationale: A two-phase prospective cohort study IRB Proposal Sara
More informationAuthor's response to reviews
Author's response to reviews Title: Diabetes duration and health-related quality of life in individuals with onset of diabetes in the age group 15-34 years - a Swedish population-based study using EQ-5D
More informationCalifornia Comprehensive Addiction Recovery Act; Physical Capacity Expansion for Addiction Treatment
California Comprehensive Addiction Recovery Act; Physical Capacity Expansion for Addiction Treatment (a) The Legislature finds and declares all of the following: 1. There are only 25 hospitals in California
More informationDrug Surveillance and Effectiveness Epidemiology Research - Questions to Ask your Epidemiologist
Drug Surveillance and Effectiveness Epidemiology Research - Questions to Ask your Epidemiologist Roberta Glass, OptumInsight Life Sciences, Waltham, Massachusetts ABSTRACT As a SAS analyst starting work
More informationImproved IPGM: Demonstrating the Value to both Patients and Hospitals
Improved IPGM: Demonstrating the Value to both Patients and Hospitals Osama Hamdy, MD, PhD, FACE Medical Director, Inpatient Diabetes Program Joslin Diabetes Center Harvard Medical School, Boston, MA Cost
More informationAuthor's response to reviews
Author's response to reviews Title: Diagnostic accuracy of point-of-care testing for acute coronary syndromes, heart failure and thromboembolic events in primary care: a cluster-randomised controlled trial
More informationResults of the liberalisation of Medisave for a population-based diabetes management programme in Singapore
Results of the liberalisation of Medisave for a population-based diabetes management programme in Singapore Woan Shin TAN 1, Yew Yoong DING 1, 2, Christine WU 3, Bee Hoon HENG 1 1 Health Services and Outcomes
More informationPEER REVIEW HISTORY ARTICLE DETAILS VERSION 1 - REVIEW. Randi Selmer Senior Researcher Norwegian Institute of Public Health Norway
PEER REVIEW HISTORY BMJ Open publishes all reviews undertaken for accepted manuscripts. Reviewers are asked to complete a checklist review form (see an example) and are provided with free text boxes to
More informationLow Tolerance Long Duration (LTLD) Stroke Demonstration Project
Low Tolerance Long Duration (LTLD) Stroke Demonstration Project Interim Summary Report October 25 Table of Contents 1. INTRODUCTION 3 1.1 Background.. 3 2. APPROACH 4 2.1 LTLD Stroke Demonstration Project
More informationCost-of-illness analysis in the EGB database
-of-illness analysis in the EGB database FRESHER WP5 V4.1-06.09.17 CORTAREDONA Sébastien (sebastien.cortaredona@inserm.fr) VENTELOU Bruno (bruno.ventelou@inserm.fr) Changelog: We added a new table Table
More informationTitle: Home Exposure to Arabian Incense (Bakhour) and Asthma Symptoms in Children: A Community Survey in Two Regions in Oman
Author's response to reviews Title: Home Exposure to Arabian Incense (Bakhour) and Asthma Symptoms in Children: A Community Survey in Two Regions in Oman Authors: Omar A Al-Rawas (orawas@squ.edu.om) Abdullah
More informationChapter 18 Section 2. EXPIRED - Department Of Defense (DoD) Cancer Prevention And Treatment Clinical Trials Demonstration
s And Pilot Projects Chapter 18 Section 2 EXPIRED - Department Of Defense (DoD) Cancer Prevention And Treatment Clinical Trials 1.0 PURPOSE The purpose of this demonstration is to improve TRICARE-eligible
More informationShaping Diabetes Services in Southern Derbyshire. A vision for Diabetes Services For Southern Derbyshire CCG
Shaping Diabetes Services in Southern Derbyshire A vision for Diabetes Services For Southern Derbyshire CCG Vanessa Vale Commissioning Manager September 2013 Contents 1. Introduction 3 2. National Guidance
More informationSpending estimates from Cancer Care Spending
CALIFORNIA HEALTHCARE FOUNDATION August 2015 Estimating Cancer Care Spending in the California Medicare Population: Methodology Detail This paper describes in detail the methods used by Deborah Schrag,
More informationAN INDIRECT EVALUATION OF THE NATIONAL PROGRAM OF DIABETES MELLITUS STUDY CASE OF ROMANIA
Rev. Med. Chir. Soc. Med. Nat., Iaşi 2013 vol. 117, no. 2 PREVENTIVE MEDICINE - LABORATORY ORIGINAL PAPERS AN INDIRECT EVALUATION OF THE NATIONAL PROGRAM OF DIABETES MELLITUS STUDY CASE OF ROMANIA Maria
More informationFinland and Sweden and UK GP-HOSP datasets
Web appendix: Supplementary material Table 1 Specific diagnosis codes used to identify bladder cancer cases in each dataset Finland and Sweden and UK GP-HOSP datasets Netherlands hospital and cancer registry
More informationReal World Patients: The Intersection of Real World Evidence and Episode of Care Analytics
PharmaSUG 2018 - Paper RW-05 Real World Patients: The Intersection of Real World Evidence and Episode of Care Analytics David Olaleye and Youngjin Park, SAS Institute Inc. ABSTRACT SAS Institute recently
More informationAuthor's response to reviews
Author's response to reviews Title: Trends of Hepatitis A Hospitalization and Risk Factors in Canada Between 1990 and 2003 Authors: Magalie Canuel (magalie.canuel@inspq.gouv.qc.ca) Gaston De Serres (gaston.deserres@ssss.gouv.qc.ca)
More informationRe: The IHPA Draft Pricing Framework Consultation paper for public hospital services (dated 31 August 2012)
10 October 2012 The Independent Hospital Pricing Authority PO Box 1414 Woden ACT 2606 Re: The IHPA Draft Pricing Framework Consultation paper for public hospital services (dated 31 August 2012) This submission
More informationHuangdao People's Hospital
Table of contents 1. Background... 3 2. Integrated care pathway implementation... 6 (1) Workload indicators... 6 A. In eligible for care pathway... 6 B. Care pathway implementation... 7 (2) Outcome indicators...
More information8/12/2016. Outline. New CPT Code for Pre-Diabetes Education. Medicare Proposed Coverage for DPP. Medicare Proposed Coverage for DPP cont.
New CPT Code for Pre-Diabetes Education 0403T: Preventive behavior change, intensive program of prevention of diabetes using a standardized diabetes prevention program curriculum, provided to individuals
More informationTitle: Co-morbidities, complications and causes of death among people with femoral neck fracture - A three-year follow-up study.
Author s response to reviews Title: Co-morbidities, complications and causes of death among people with femoral neck fracture - A three-year follow-up study. Authors: Monica Berggren (monica.langstrom@umu.se)
More informationSetting The setting was secondary care. The economic study was carried out in Belgium.
Cost effectiveness of paclitaxel/cisplatin compared with cyclophosphamide/cisplatin in the treatment of advanced ovarian cancer in Belgium Neymark N, Gorlia T, Adriaenssen I, Baron B, Piccart M Record
More informationPopulation Health Analytics and Usage of the ACG System in the UK Stockholm, 13 th June, 2017 Alan Thompson, Director of User Support
Population Health Analytics and Usage of the ACG System in the UK Stockholm, 13 th June, 2017 Alan Thompson, Director of User Support athompson@hopkinsacg.org Content Summary of main uses of the ACG System
More informationA COMPREHENSIVE REPORT ISSUED BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS IN PARTNERSHIP WITH:
A COMPREHENSIVE REPORT ISSUED BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS IN PARTNERSHIP WITH: Amputee Coalition of America Mended Hearts National Federation of the Blind National Kidney Foundation
More informationTitle: Persistent tumor cells in bone marrow of early breast cancer patients after primary surgery are associated with inferior outcome
Author's response to reviews Title: Persistent tumor cells in bone marrow of early breast cancer patients after primary surgery are associated with inferior outcome Authors: Kjersti Tjensvoll (ktje@sus.no)
More informationTitle:Continuity of GP care is associated with lower use of complementary and alternative medical providers A population-based cross-sectional survey
Author's response to reviews Title:Continuity of GP care is associated with lower use of complementary and alternative medical providers A population-based cross-sectional survey Authors: Anne Helen Hansen
More informationCHAPTER 7 SECTION 24.1 PHASE I, PHASE II, AND PHASE III CANCER CLINICAL TRIALS TRICARE POLICY MANUAL M, AUGUST 1, 2002 MEDICINE
MEDICINE CHAPTER 7 SECTION 24.1 ISSUE DATE: AUTHORITY: 32 CFR 199.4(e)(26) I. DESCRIPTION The Department of Defense (DoD) Cancer Prevention and Treatment Clinical Trials Demonstration was conducted from
More informationTitle: How efficient are Referral Hospitals in Uganda? A Data Envelopment Analysis and Tobit Regression Approach
Author s response to reviews Title: How efficient are Referral Hospitals in Uganda? A Data Envelopment Analysis and Tobit Regression Approach Authors: Paschal Mujasi (Pmujasi@yahoo.co.uk) Eyob Asbu (zeyob@yahoo.com)
More informationTitle:The epidemiology of hospital treated traumatic brain injury in Scotland
Author's response to reviews Title:The epidemiology of hospital treated traumatic brain injury in Scotland Authors: Tara Shivaji (tarashivaji@nhs.net) Andrew Lee (Andrew.lee6@nhs.net) Nadine Dougall (nadine.dougall@stir.ac.uk)
More informationNational Diabetes Treatment and Care Programme
National Diabetes Treatment and Care Programme Introduction to and supporting documentation for VALUE BASED TRANSFORMATION FUNDING SITE SELECTION December 2016 1 Introduction and Contents The Planning
More informationAustralian, Finland and South Africa - Delving into Data to Investigate Differences in Stroke Rehabilitation
University of Wollongong Research Online Australasian Rehabilitation Outcomes Centre - AROC Centre for Health Service Development - CHSD 2005 Australian, Finland and South Africa - Delving into Data to
More informationClinical Therapeutics/Volume 38, Number 5, 2016
Corrigendum Clinical Therapeutics/Volume 38, Number 5, 2016 Corrigendum to Descriptive Comparison of Drug Treatment Persistent,, and Nondrug Treatment Patients With Newly Diagnosed Attention Deficit/Hyperactivity
More informationSetting The setting was secondary care. The economic study was carried out in the USA.
Economic consequences of routine coronary angiography in low- and intermediate-risk patients with unstable angina pectoris Desai A S, Solomon D H, Stone P H, Avorn J Record Status This is a critical abstract
More informationIntegrated Diabetes Care in Oxfordshire -patient's perspective. Avril Surridge
Integrated Diabetes Care in Oxfordshire -patient's perspective Avril Surridge Today How does diabetes care in Oxfordshire look like from a patient s perspective? Good things What could be improved? National
More informationAttn: Alicia Richmond Scott, Pain Management Task Force Designated Federal Officer
March 18, 2019 Office of the Assistant Secretary of Health U.S. Department of Health and Human Services 200 Independence Avenue SW, Room 736E Washington, DC 20201 Attn: Alicia Richmond Scott, Pain Management
More informationSetting The setting was hospital and the economic analysis was carried out in the Netherlands.
Impact of goal-oriented and model-based clinical pharmacokinetic dosing of aminoglycosides on clinical outcome: a cost-effectiveness analysis van Lent-Evers N A, Mathot R A, Geus W P, van Hout B A, Vinks
More informationPEER REVIEW HISTORY ARTICLE DETAILS TITLE (PROVISIONAL)
PEER REVIEW HISTORY BMJ Open publishes all reviews undertaken for accepted manuscripts. Reviewers are asked to complete a checklist review form (http://bmjopen.bmj.com/site/about/resources/checklist.pdf)
More informationPHARMO Database Network
Pros & cons in Oncology studies PHARMO Myrthe Database van Herk-Sukel, Network PhD 1 Disclosure Myrthe van Herk-Sukel is an employee of the PHARMO Institute for Drug Outcomes Research. This independent
More informationTITLE: Delivery of Electroconvulsive Therapy in Non-Hospital Settings: A Review of the Safety and Guidelines
TITLE: Delivery of Electroconvulsive Therapy in Non-Hospital Settings: A Review of the Safety and Guidelines DATE: 08 May 2014 CONTEXT AND POLICY ISSUES Electroconvulsive therapy (ECT) is a treatment that
More informationType of intervention Primary prevention. Economic study type Cost-effectiveness analysis.
A hospital perspective on the cost-effectiveness of beta-blockade for prophylaxis of atrial fibrillation after cardiothoracic surgery Gillespie E L, White C M, Kluger J, Sahni J, Gallagher R, Coleman C
More informationCost-utility analysis of tympanomastoidectomy for adults with chronic suppurative otitis media Wang P C, Jang C H, Shu Y H, Tai C J, Chu K T
Cost-utility analysis of tympanomastoidectomy for adults with chronic suppurative otitis media Wang P C, Jang C H, Shu Y H, Tai C J, Chu K T Record Status This is a critical abstract of an economic evaluation
More informationEvidence from a Pharmacy Access Program TERESA B. GIBSON, PHD SENIOR DIRECTOR, HEALTH OUTCOMES OCTOBER 27, 2011
Evidence from a Pharmacy Access Program TERESA B. GIBSON, PHD SENIOR DIRECTOR, HEALTH OUTCOMES OCTOBER 27, 2011 OVERVIEW Gibson TB, Mahoney J, Ranghell K, Cherney BJ, McElwee N. Value-Based Insurance Plus
More informationDATA MINING METHODS FOR THE RESEARCH OF OUTCOME ANALYSIS OF ARTERIOVENOUS FISTULA IN TAIWAN
DATA MINING METHODS FOR THE RESEARCH OF OUTCOME ANALYSIS OF ARTERIOVENOUS FISTULA IN TAIWAN YI-HORNG LAI Department of Health Care Administration, Oriental Institute of Technology, Taiwan E-mail: FL006@mail.oit.edu.tw
More informationIn addition, we have asked an English-editing service to edit the text, and you will find an English-edited version of the paper submitted as well.
Author s response to reviews Title: Resource Use and Disease Course in Dementia - Nursing Home (REDIC-NH): A Norwegian Cohort Study from Admission to a Nursing Home until Death. A description of study
More informationTexas Health Insurance Coverage for Tobacco Dependence: 2007
Texas Health Insurance Coverage for Tobacco Dependence: 2007 Phyllis Gingiss, Dr.P.H. Victoria Mosier, M.A. Sandra Coombs Khurram Shahzad, B.S. April 30, 2007 Prepared by the University of Houston Health
More informationPage 4. Line 7 and 8. Do these stats refer to children worldwide? Please clarify.
Reviewer s report Title: Management of severe acute malnutrition by cow milk in resource contraints settings: experience of the Nutritional Centre of the University Clinics of Graben Version: 0 Date: 27
More informationTitle: Tiotropium's cost-effectiveness for the treatment of COPD: a cost-utility analysis under real-world conditions.
Author's response to reviews Title: Tiotropium's cost-effectiveness for the treatment of COPD: a cost-utility analysis under real-world conditions. Authors: Mattias Neyt (mattias.neyt@kce.fgov.be) Stephan
More informationSetting The setting was primary care. The economic study was carried out in the USA.
Glimepiride versus pioglitazone combination therapy in subjects with type 2 diabetes inadequately controlled on metformin monotherapy: results of a randomized clinical trial Umpierrez G, Issa M, Vlajnic
More informationSetting The setting was secondary care. The economic study was carried out in Switzerland.
Cost-effectiveness of B-type natriuretic peptide testing in patients with acute dyspnea Mueller C, Laule-Kilian K, Schindler C, Klima T, Frana B, Rodriguez D, Scholer A, Christ M, Perruchoud A P Record
More informationPlease find attached the detailed reply to all reviewer s comments/suggestions.
Author s response to reviews Title: The Impact of the Time of Drug Administration on the Effectiveness of Combined Treatment of Hypercholesterolemia with ROSuvastatin and EZEtimibe (RosEze): study protocol
More informationDiabetes Quality Improvement Initiative
Diabetes Quality Improvement Initiative Community Care of North Carolina 2300 Rexwoods Drive, Ste. 100 Raleigh, NC 27607 (919) 745-2350 www.communitycarenc.org 2007 Background The Clinical Directors of
More informationSUCCESSFUL APPROACHES TO TREATMENT FOR OPIOID ADDICTION: FOCUS ON VETERANS
Sponsored by: September 2017 SUCCESSFUL APPROACHES TO TREATMENT FOR OPIOID ADDICTION: FOCUS ON VETERANS Developed by: THE RESEARCH 2 The Economist Intelligence Unit has conducted a research program, sponsored
More informationTownsville Broadband Diabetes Telehealth Trial EVALUATION REPORT. May 2015
Townsville Broadband Diabetes Telehealth Trial EVALUATION REPORT May 2015 A report by the Centre for Applied Health Economics (CAHE), Griffith University www.healtheconomics.com.au EXECUTIVE SUMMARY BACKGROUND
More informationPractical Predictive Analytics. John Cuddeback, MD, PhD AMA IPPS November 11, 2016
Practical Predictive Analytics John Cuddeback, MD, PhD AMA IPPS November 11, 2016 AMGA s Work in Analytics Advocacy: Align payment incentives around population health Programs: Help members redesign delivery
More informationLAIs and the Challenge of Medication Non-Adherence The Care Transitions Network
LAIs and the Challenge of Medication Non-Adherence The Care Transitions Network Lauren Hanna, M.D. The Zucker Hillside Hospital Northwell Health National Council for Behavioral Health Montefiore Medical
More informationTitle: Are time-trends of smoking among pregnant immigrant women in Sweden determined by cultural or socioeconomic factors?
Author's response to reviews Title: Are time-trends of smoking among pregnant immigrant women in Sweden determined by cultural or socioeconomic factors? Authors: Kontie Moussa (kontie.moussa@med.lu.se)
More informationmedicaid and the The Role of Medicaid for People with Diabetes
on medicaid and the uninsured The Role of for People with Diabetes November 2012 Introduction Diabetes is one of the most prevalent chronic conditions and a leading cause of death in the United States.
More informationSponsor / Company: Sanofi Drug substance(s): Insulin Glargine. Study Identifiers: NCT
These results are supplied for informational purposes only. Prescribing decisions should be made based on the approved package insert in the country of prescription. Sponsor / Company: Sanofi Drug substance(s):
More informationSource of effectiveness data The effectiveness data were derived from a review or synthesis of completed studies.
The 23-valent pneumococcal polysaccharide vaccine. Part II: a cost-effectiveness analysis for invasive disease in the elderly in England and Wales Melegaro A, Edmunds W J Record Status This is a critical
More informationAuthor(s) : Title: HERCA WG Medical Applications / Sub WG Exposure of Asymptomatic Individuals in Health Care
Author(s) : Juergen Griebel, (Bfs, DE) Steve Ebdon-Jackson (HPA, UK) Title: HERCA WG Medical Applications / Sub WG Exposure of Asymptomatic Individuals in Health Care Position Paper on Screening Summary:
More informationOnline Supplementary Material
Section 1. Adapted Newcastle-Ottawa Scale The adaptation consisted of allowing case-control studies to earn a star when the case definition is based on record linkage, to liken the evaluation of case-control
More informationBurden of Hospitalizations Primarily Due to Uncontrolled Diabetes: Implications of Inadequate Primary Health Care in the United States
Diabetes Care In Press, published online February 8, 007 Burden of Hospitalizations Primarily Due to Uncontrolled Diabetes: Implications of Inadequate Primary Health Care in the United States Received
More informationInclude Substance Use Disorder Services in New Hampshire Medicaid Managed Care
Include Substance Use Disorder Services in New Hampshire Medicaid Managed Care New Futures mission is to advocate, educate, and collaborate to reduce alcohol and other drug problems in New Hampshire. Expanding
More informationMJ - Decision on Manuscript ID BMJ
MJ - Decision on Manuscript ID BMJ.2018.044966 Body: 12-Jul-2018 Dear Dr. Khandwala Manuscript ID BMJ.2018.044966 entitled "The Association of Paternal Age and Perinatal Outcomes between 2007 and 2016
More informationThe dramatic growth of managed. Use of Psychiatrists, Psychologists, and Master s-level Therapists in Managed Behavioral Health Care Carve-Out Plans
Use of Psychiatrists, Psychologists, and Master s-level Therapists in Managed Behavioral Health Care Carve-Out Plans Roland Sturm, Ph.D. Ruth Klap, Ph.D. Objective: Outpatient claims data from a managed
More informationJune 9, Michael L. LeFevre, M.D., M.S.P.H. Chair, United States Preventive Services Task Force 540 Gaither Road Rockville, MD 20850
June 9, 2014 Michael L. LeFevre, M.D., M.S.P.H. Chair, United States Preventive Services Task Force 540 Gaither Road Rockville, MD 20850 Re: Draft Recommendation Statement: Behavioral Counseling to Promote
More informationDiscussion of Changes in the Draft Preamble
Discussion of Changes in the Draft Preamble Prepared by the staff of the IARC Monographs programme 31 August 2005 This paper describes the major changes that appear in the draft Preamble that will be reviewed
More informationPalliative Care and End of Life Care
Palliative Care and End of Life Care Relevant Data and References Victorian Population 1 Total Victorian Population as at June 2016 was 6.1 million (6,179,249) Victorian 60 plus population as at June 2016
More informationValue of Hospice Benefit to Medicaid Programs
One Pennsylvania Plaza, 38 th Floor New York, NY 10119 Tel 212-279-7166 Fax 212-629-5657 www.milliman.com Value of Hospice Benefit May 2, 2003 Milliman USA, Inc. New York, NY Kate Fitch, RN, MEd, MA Bruce
More informationZERO SUICIDE DATA ELEMENTS WORKSHEET
ZERO SUICIDE DATA ELEMENTS WORKSHEET Description and Instructions This worksheet is intended to assist health and behavioral health care organizations in developing a data-driven, quality improvement approach
More informationCover Page. The handle holds various files of this Leiden University dissertation.
Cover Page The handle http://hdl.handle.net/1887/22306 holds various files of this Leiden University dissertation. Author: Vochteloo, Anne Jochem Hendrik Title: Determinants of outcome in hip fracture
More informationMENTAL HEALTH INDICATORS: WITHIN 30-DAY HOSPITAL RE-ADMISSION
MENTAL HEALTH INDICATORS: WITHIN 30-DAY HOSPITAL RE-ADMISSION OECD HCQI Expert Meeting Rie Fujisawa November 16 th 2012 Within 30-day hospital re-admission Data are collected in two different ways: The
More informationManuscript ID BMJ entitled "Benzodiazepines and the Risk of Allcause Mortality in Adults: A Cohort Study"
12-Jan-2017 Dear Dr. Patorno Manuscript ID BMJ.2016.036319 entitled "Benzodiazepines and the Risk of Allcause Mortality in Adults: A Cohort Study" Thank you for sending us your paper. We sent it for external
More informationAuthorized By: Elizabeth Connolly, Acting Commissioner, Department of Human
HUMAN SERVICES 49 NJR 6(1) June 5, 2017 Filed May 10, 2017 DIVISION OF MENTAL HEALTH AND ADDICTION SERVICES Medical Necessity Review Tool for Substance Use Disorders Proposed New Rules: N.J.A.C. 10:163
More informationThe management of adult diabetes services in the NHS
REPORT BY THE COMPTROLLER AND AUDITOR GENERAL HC 21 SESSION 2012-13 23 MAY 2012 Department of Health The management of adult diabetes services in the NHS Our vision is to help the nation spend wisely.
More informationHEALTH CARE EXPENDITURES ASSOCIATED WITH PERSISTENT EMERGENCY DEPARTMENT USE: A MULTI-STATE ANALYSIS OF MEDICAID BENEFICIARIES
HEALTH CARE EXPENDITURES ASSOCIATED WITH PERSISTENT EMERGENCY DEPARTMENT USE: A MULTI-STATE ANALYSIS OF MEDICAID BENEFICIARIES Presented by Parul Agarwal, PhD MPH 1,2 Thomas K Bias, PhD 3 Usha Sambamoorthi,
More informationExecutive Summary. Evaluation of the therapeutic benefits and harms of exenatide 1. IQWiG Reports - Commission No. A05-23
IQWiG Reports - Commission No. A05-23 Evaluation of the therapeutic benefits and harms of exenatide 1 Executive Summary 1 Translation of the executive summary of the final report Bewertung des therapeutischen
More informationPublic Reporting and Self-Regulation: Hospital Compare s Effect on Sameday Brain and Sinus Computed Tomography Utilization
Public Reporting and Self-Regulation: Hospital Compare s Effect on Sameday Brain and Sinus Computed Tomography Utilization Darwyyn Deyo and Danny R. Hughes December 1, 2017 Motivation Widespread concerns
More informationPEER REVIEW HISTORY ARTICLE DETAILS VERSION 1 - REVIEW. I have no competing interests 17-Feb-2013
PEER REVIEW HISTORY BMJ Open publishes all reviews undertaken for accepted manuscripts. Reviewers are asked to complete a checklist review form (see an example) and are provided with free text boxes to
More informationAdvances in Alignment, Measurement, and Performance MY 2017 Results Highlights
Advances in Alignment, Measurement, and Performance MY 2017 Results Highlights Align. Measure. Perform. (AMP) Programs Launched in 2003, VBP4P is a statewide performance improvement program and one of
More information