PluroGel Burn and Wound Dressing Chicago. 23 May 2014
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1 PluroGel Burn and Wound Dressing Chicago 23 May 2014
2 A NEW, BREAKTHROUGH SURFACTANT BASED BIOMATERIAL WITH A SPECIAL MOLECULAR STRUCTURE
3 PLUROGEL BIOMATERIAL SPECIAL MOLECULAR STRUCTURE PLUROGEL MICELLE GEL MATRIX Hydrophobic Inside PLUROGEL BIOMATERIAL Unique Molecular Structure Spherical PluroGel Micelles Formed into the PLUROGEL MICELLE GEL MATRIX
4 PLUROGEL BIOMATERIAL PROVIDES PLUROGEL MICELLE GEL MATRIX Hydrophobic Inside Surfactant that Uniquely is Cell Friendly and Biocompatible Facilitates Continuous Wound Cleaning Process Facilitates Autolytic Debridement Reported Less Tissue Damage on Dressing Change Reported Faster, Easier Dressing Change Reported Reduction in Pain Can Maintain Blood Flow Can Increase Tissue Oxygenation Can Prevent and Break up Biofilm Can Save Damaged Cells
5 PLUROGEL SAVING DAMAGED CELLS WITHOUT PLUROGEL WITH PLUROGEL CELL CONTINUES TO FAIL DAMAGE CELL DEATH Without PLUROGEL Necrosis or Apoptosis
6 PLUROGEL SAVING DAMAGED CELLS WITHOUT PLUROGEL WITH PLUROGEL INTRODUCTION OF PLUROGEL CELL CONTINUES TO FAIL DAMAGE CELL DEATH Without PLUROGEL Necrosis or Apoptosis
7 PLUROGEL SAVING DAMAGED CELLS WITHOUT PLUROGEL WITH PLUROGEL INTRODUCTION OF PLUROGEL CELL CONTINUES TO FAIL DAMAGE THE PLUROGEL MGM FILLS DAMAGED CELL MEMBRANE CELL DEATH Without PLUROGEL Necrosis or Apoptosis
8 PLUROGEL SAVING DAMAGED CELLS WITHOUT PLUROGEL WITH PLUROGEL INTRODUCTION OF PLUROGEL DAMAGE CELL CONTINUES TO FAIL THE PLUROGEL MGM FILLS DAMAGED CELL MEMBRANE CELL DEATH Without PLUROGEL Necrosis or Apoptosis HEALTHY CELL CELL SURVIVAL with PLUROGEL
9 BENEFICIAL & USED IN ALL STAGES OF WOUND HEALING + Correlation to Improved Healing + Reduced Pain PluroGel Products PluroGel Products WOUND HEALING PROGRESSION MODEL HEALED
10 PATIENT 1 HISTORY and Wound 1: Male, 82 years, not insulin dependent diabetes, peripheral arterial disease Walking distance 100 meters, after amputation of the 4th and 5th toe and incision on the sole of the foot due to the arterial disease, neuropathic foot. Daily dressing change, clean with Octenisept with adopted shoe with low pressure sole. End December 3, Start: July 3, 2013 End: December 3, Months
11 PATIENT 1 Wound 2 (on Sole of Foot) Start: July 3, 2013 End: December 3, Months
12 PATIENT 2 HISTORY and Wound 1: Male, 58 years, not insulin dependent diabetes, peripheral arterial disease. Walking distance 500m, nicotine abuse, hypertonus, Staphylococcus +++and Enterococcus +++ in the swab. Wound on the left knee and 1 st toe left. Start: July 10, 2013 End: September 12, Months
13 PATIENT 3 HISTORY and Wound 1: Male, 76 years, not insulin dependent diabetes, peripheral arterial disease. Walking distance 80 meters, past PTA of the left leg, neuropathic foot. Past amputation of the 1 st toe left caused by peripheral arterial disease. Pseudomonas+++ and Enterococcus+++ in the swab. Ulcer on amputation site and near inner ankle left side. Begin May 3, 2013 with beta iodine Change to PluroGel BWD after 4 weeks (about June 3, 2013) cleaning with beta iodine fluid, changing every day, pressure reduction with wound care shoe, compression therapy with bandage Start: May 3, 2013 (Start: PluroGel BWD ~ June 3, 2013) End: August 7, Months
14 PATIENT 3 Wound 2 (on Ankle): Start: May 3, 2013 (Start: PluroGel BWD ~ June 3, 2013) End: July 3, Month
15 PATIENT 4 HISTORY: Female, 79 years, peripheral arterial disease. Walking distance 200m, varikosis, mixed ulcer inner ankle left. Staphylococcus +++ in the swab. Start March 15, 2013 with 4 weeks combination PluroGel BWD with cortisone, compression. Start about April 15, 2013 with PluroGel BWD only, cleaning with NaCl. Start: PluroGel BWD Combo March 15, 2013 Start: PluroGel BWD Only ~ April 15, 2013 End: July 9, ¾ Months
16 PATIENT 5 HISTORY: Female, 88 years, peripheral arterial disease. Walking distance 50 meters, varicose, neuropathic disease, ulcer heel left side. Staphylococcus+++ in the swab. Start March 28, 2013 with PluroGel PSSD, beta iodine fluid for wound cleaning, surgical debridement, decrease of pressure with wound care shoe. Change April 25, 2013 to PluroGel BWD, beta iodine continuous cleaning. End June 27, Start: PluroGel PSSD March 28, 2013 Start: PluroGel BWD April 25, 2013 End: June 27, 2013 Months: 3 Months
17 PATIENT 5 Photos: March 28, 2013 Before Debridement Start: PluroGel PSSD March 28, 2013 Start: PluroGel BWD April 25, Months March 28, 2013 After Debridement May 25, 2013 End: June 27, 2013
18 PATIENT 6 HISTORY: Patient received a 2nd degree burn of the R forearm on March 11, Patient treated for approximately 1 month at another facility with collagenase and bacitracin. Patient presented to UVA April 9, 2014 for an evaluation of next steps skin graft recommended; patient refused. Being Clean" wound, UVA started PluroGel BWD covered with Adaptic and then gauze wrap with daily change. On patient return to UVA 2 weeks later everyone was very pleased with the progress. Patient s wife said "I could watch it healing with every dressing change. That gel is fantastic". Patient has not retuned to UVA. End April 23, Start: PluroGel BWD April 9, 2014 End: April 23, 2014
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