VENKATESH NAGARADDI, MD
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1 - 1 - VENKATESH NAGARADDI, MD 7777 Forest Lane, C-650 Dallas, Texas vnagaraddi@hotmail.com (972) NEUROLOGY/EPILEPTOLOGY North Dallas Epilepsy Sep, 16 present Director of Neurodiagnostics at Presbyterian Hospital of Dallas May, 17 - present Director of Neurodiagnostics at Medical City Dallas Hospital Sep, 09 Aug, 16 Active staff at Medical City Dallas Hospital Sep, 07 present Active staff at Presbyterian Hospital of Dallas Sep, 07 present Neurology consultants of Dallas Sep, 15 Aug, 16 Texas Epilepsy Group Sep, 07 Aug, 15 POST-GRADUATE TRAINING Epilepsy Fellowship at Cleveland Clinic Jul, 05 Jun, 07 Neurology Residency at University Hospitals, Cleveland Jul, 02 Jun, 05 Medicine Internship at AtlantiCare Regional Medical Center Jul, 01 Jun, 02 Epilepsy Research at University of Kansas Medical Center Jun, 99 Jun, 01 BACHELOR OF MEDICINE/SURGERY (MBBS) Kasturba Medical College, Manipal University, Mangalore, India Aug, 92 Aug, 98 Graduated Honors with distinction. CERTIFICATION/MEMBERSHIP/LICENSURE American Board of Neurology and Psychiatry. American Board of Clinical Neurophysiology American Academy of Neurology American Epilepsy Society Texas Neurological Society Texas Medical Association Texas Medical Board PRESENTATIONS Poly frequency stimulation delays kindling in rats" AES meeting. Effect of 1 Hz stimulation on kindled seizures in rats AES meeting Focal Cortical Dysplasia Neurology Residents Scholar Program. The prevalence of Hyperglycemia in the Neuro-Intensive Care Unit and its effect on length of stay and cost of care 2004 AAN meeting.
2 - 2 - PUBLICATIONS Effect of one hertz stimulation on kindled seizures in rats. Nagaraddi V, Wilkinson SB, Osorio I. Epilepsia; 2001; 41(S7): Seizure blockage with automated "closed-loop" electrical stimulation: A pilot study. Osorio I et al, Nagaraddi V. Epilepsia; 2002; 42(S7): 207. Electrical and thermal behavior of intracranial electrodes during magnetic resonance imaging: Bhavaraju NC, Nagaraddi V, Osorio I. Epilepsia; 2002; 42(S7): 62. Electrical and Thermal Behavior of non-ferrous noble metal electrodes exposed to MRI fields. Bhavaraju NC, Nagaraddi V, Osorio I. Magnetic Resonance Imaging; 2002; 20: Chapter 54 titled Autonomic seizures: Localization and Lateralizing Value in Textbook of Epilepsy Surgery, Editors: H. Luders, I. Najm & W. Bingaman Efficacy of once-daily extended-release topiramate (USL255): a subgroup analysis based on the level of treatment resistance. Hogan RE, Blatt I, Lawson B, Nagaraddi V, Fakhoury TA, Anders B, Clark AM, Laine D, Halvorsen MB, Chung SS. Epilepsy Behav Dec; 41: Once-daily USL255 as adjunctive treatment of partial-onset seizures: randomized phase III study. Chung SS, Fakhoury TA, Hogan RE, Nagaraddi VN, Blatt I, Lawson B, Arnold S, Anders B, Clark AM, Laine D, Meadows RS, Halvorsen MB; PREVAIL Study Group. Epilepsia Jul; 55(7): Multi-signal Analsis for Epilepsy Seizure Monitoring. Cogan D, Birjandtalab J, Nourani M, Harvey J, Nagaraddi V. Int J Neural Syst Feb;27(1): Epub 2016 Apr 7. Epielptic seizure detection using wristworn biosensors. Cogan D, Nourani M, Harvey J, Nagaraddi V. Conf Proc IEEE Eng Med Biol Soc. 2015;2015: doi: /EMBC RESEARCH Protocol GWEP 1415: 2015 PI An Open-Label, Multicenter, Follow-Up Study to Evaluate The Long-Term Safety And Efficacy of Cannabidiol as adjunctive treatment of seizures associate with Lennox Gastaut Syndrome in children and adults. Protocol GWEP 1423: 2015 PI A Randomized, Double-Blind, Placebo Controlled Study to Evaluate the Efficacy And Safety Of Cannabidiol as adjunctive treatment of seizures associate with Lennox Gastaut Syndrome in children and adults. Protocol MID301: NOV 2013 PI A Randomized, Double-Blind, Placebo-Controlled Trial Treating Subjects with International Bouts of Increased Seizure Activity in the Epilepsy Monitoring Unit (EMU)
3 - 3 - Protocol SP954: OCT 2012 PI An Open-Label, Multicenter, Multinational Study of Lacosamide as First Add-On Antiepileptic Drug (AED) Treatment in Subjects with Partial Onset Seizures Protocol NO1358: 2010 PI A Randomized, Double-Blind, Placebo Controlled, Multicenter, Parallel Group Study to Evaluate the Efficacy and Safety Of Brivaracetam in Subjects (> 16 To 80 Years Old) With Partial Onset Seizures Protocol NO1379: 2010 PI An Open-Label, Multicenter, Follow-Up Study to Evaluate the Long-Term Safety And Efficacy of Brivaracetam Used As Adjunctive Treatment In Subjects Aged 16 Years Or Older With Partial Onset Seizures Protocol P09-004: 2010 PI A Randomized, Multicenter, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 3 Study to Evaluate the Efficacy and Safety of USL255 as Adjunctive Therapy in Patients with Refractory Partial-Onset Seizures Protocol P09-005: 2010 PI Open-Label Extension Study to Evaluate the Safety of USL255 as Adjunctive Therapy in Patients with Refractory Partial-Onset Seizures who had Participated in P09-004, a Randomized, Multicenter, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 3 Study P Protocol CARISEPY3013/3014: JAN 2009 PI A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of Carisbamate as Adjunctive Therapy in Subjects with Partial Onset Seizures, Followed by an Open-Label Extension Study Protocol E-37: MAR 2013 Sub-I VNS Therapy Automatic Magnet Mode Outcomes Study in Epilepsy Patients Exhibiting Ictal Tachycardia Protocol IPX218-B12-02: MAR 2013 Sub-I An Inpatient Open-Label Usability Study of IPX218 in Subjects with Epilepsy Protocol PTG116878: JAN 2013 Sub-I Study PTG116878, a Dose-Optimization Study of Ezogabine/Retigabine Immediate Release Tablets versus Placebo in the Adjunctive Treatment of Subjects with Partial-Onset Seizures Protocol SP0993: JAN 2013 Sub-I A Multicenter, Double-Blind, Double-Dummy, Randomized, Positive-Controlled Study Comparing the Efficacy and Safety of Lacosamide (200 to 600mg/day) to Controlled Release Carbamazepine (400 to 1200mg/day), Used as Monotherapy in Subjects (> 16 Years) Newly or Recently Diagnosed with Epilepsy and Experiencing Partial-Onset or Generalized Tonic-Clonic Seizures
4 - 4 - Protocol SP0982: NOV 2012 Sub-I A Double-Blind, Randomized, Placebo-Controlled, Parallel-Group, Multicenter Study to Evaluate the Efficacy and Safety of Lacosamide as Adjunctive Therapy for Uncontrolled Primary Generalized Tonic-Clonic Seizures in Subjects with Idiopathic Generalized Epilepsy Protocol E2007-G : SEP 2012 Sub-I A Double-blind, Randomized, Placebo-controlled, Multicenter, Parallel-group Study with an Open-label Extension Phase to Evaluate the Efficacy and Safety of Adjunctive Perampanel in Primary Generalized Tonic-Clonic Seizures Protocol NO1372: AUG 2012 Sub-I An Open-Label, Multicenter, Follow-up Study to Evaluate the Long-Term Safety and Efficacy of Brivaracetam Used as Adjunctive Treatment in Subjects Aged 16 Years or Older with Epilepsy Protocol NO1395: AUG 2012 Sub-I An Open-Label, Multicenter, Single-Arm, Study to Evaluate the Reduction in Nonpsychotic Behavioral Side Effects in Subjects with Epilepsy Switching from Levetiracetam to Brivaracetam Due to Nonpsychotic Behavioral Side Effects Protocol BIA : APR 2010 Sub-I Efficacy and Safety of Esclicarbazepine Acetate (BIA 2-093) As Adjunctive Therapy For Refractory Partial Seizures In a Double-Blind, Randomized, Placebo-Controlled, Parallel-Group, Multicentre Clinical Trial Protocol /050: FEB 2009 Sub-I Double-Blind, Randomized, Historical Control Study of the Safety and Efficacy of Study drug Monotherapy in Subjects with Partial Epilepsy Not Well Controlled By Current Antiepileptic Drugs Protocol SP925: NOV 2008 Sub-I A Multicenter, Open-label Trial to Assess the Safety and Tolerability of a Single Intravenous Loading Dose of Lacosamide Followed by Oral Lacosamide Maintenance as Adjunctive Therapy in Subjects with Partial-onset Seizures Protocol SP926: NOV 2008 Sub-I A Multicenter, Open-label Extension Trial to Assess the Long-term Safety and Tolerability of Lacosamide as Adjunctive Therapy in Subjects with Partial-onset Seizures JPI Protocol : OCT 2008 Sub-I A Phase 2a, Open-label, Proof-of-Concept Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Intranasal study drug in Adult Subjects with Epileptic Seizures Protocol E2007-G : JUN 2008 Sub-I A 14-month open-label extension Phase of the Double-Blind, Placebo-Controlled, Dose Escalation. Parallel-Group Study to Evaluate the Efficacy and Safety of E2007 (perampanel) Given as Adjunctive Therapy in Subjects with Refractory Partial Seizures
5 - 5 - Protocol E2007-G : MAR 2008 Sub-I A Double-Blind, Placebo-Controlled, Dose Escalation, Parallel-Group Study to Evaluate the Efficacy and Safety of E2007 (perampanel) Given as Adjunctive Therapy in Subjects with Refractory Partial Seizures Protocol NO1253: FEB 2008 Sub-I An international, double-blind, parallel-group, placebo-controlled, randomized study: evaluation of the efficacy and safety of Brivaracetam in subjects (> 16 to 70 years old) with Partial Onset Seizures Protocol LEP105974: 2007 Sub-I A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Effects of study drug Tablets on Comorbid Depressive Symptoms in Subjects with Epilepsy Protocol : OCT 2007 Sub-I A double-blind, randomized, placebo-controlled study to evaluate the safety, tolerability, and efficacy of study drug as add-on therapy in adult subjects with epilepsy consisting of uncontrolled partial-onset seizures Protocol : OCT 2007 Sub-I An open-label extension study to evaluate the safety, tolerability, and efficacy of study drug as add-on therapy in adult patients with epilepsy consisting of uncontrolled partial-onset seizures/ Protocol OV-1015: AUG 2007 Sub-I A Sequential, Open-Label Study of the Pharmacokinetics and Safety of Intravenous Carbamazepine Relative to Oral Carbamazepine in Adult Patients with Epilepsy Protocol VRX-RET-E22-302: JUN 2007 Sub-I A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Parallel-Group Phase 3 Study to Determine the Efficacy and Safety of Two Doses of Retigabine (900 mg/day and 600 mg/day) Used as Adjunctive Therapy in Refractory Epilepsy Patients With Partial-Onset Seizure Protocol NO1281: MAY 2007 Sub-I An open-label, long term follow-up study with Study drug for treatment of partial onset seizures Protocol SP902: MAY 2007 SUB-I A Historical-controlled, Multicenter, Double-blind, Randomized Trial to Assess the Efficacy and Safety of Conversion to study drug 400mg/day Monotherapy in Subjects with Partial-onset Seizures Protocol NO1280: APR 2007 Sub-I A multi-center, double-blind, historical control, randomized conversion to monotherapy study with study drug for treatment of partial onset seizures Protocol E2080-A : MAR 2007 Sub-I An Open-Label Extension Study of Rufinamide Given as Adjunctive Therapy in Patients with Refractory Partial Seizures
6 - 6 - Protocol VRX-RET-E22-303: MAR 2007 Sub-I A multicenter, open-label, long-term, safety, tolerability and efficacy study of retigabine in adult epilepsy patients with partial-onset seizures (extension of study VRX-RET-E22-301) Protocol SP904: JAN 2007 Sub-I A Multicenter, Open-label Extension Trial to Assess the Long-term Use of Lacosamide Monotherapy and Safety of Lacosamide Monotherapy and Adjunctive Therapy in Subjects with Partial-onset Seizures Protocol K : JAN 2007 Sub-I A Phase 2, Randomized, Double-blind, Parallel, Placebo-Controlled, Multicenter Study, with Optional Open-Label Continuation, of The Efficacy and Safety of study drug Auto-Injector (study drug Injection) for the Management of Selected, Refractory, Patients with Epilepsy who Require Intermittent Medical Intervention to Control Episodes of Acute Repetitive Seizures
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