BIBLIOGRAFIA. ANDERSON, G.D. (1998) - A mechanistic approach to antiepileptic drug interactions. Ann. Pharmacother. 32 (1998)
|
|
- Robert Marsh
- 6 years ago
- Views:
Transcription
1 VII. BIBLIOGRAFIA
2 148
3 BIBLIOGRAFIA ANDERSON, G.D. (1998) - A mechanistic approach to antiepileptic drug interactions. Ann. Pharmacother. 32 (1998) BENES, J. [et al.] (1999) - Anticonvulsant and Sodium Channel-Blocking Properties of Novel 10,11-Dihydro-5H-dibenz[b,f]azepine-5-carboxamide Derivatives. J. Med. Chem. 42 (1999) BERTRAND, P.; DUBAS, F. (1990) - Épilepsies: étiologie, diagnostic, évolution, pronostic et principes du traitement. Nouv. Quest. 2:6 (1990) BESAG, F.M.C. [et al.] (1998) Carbamazepine toxicity with Lamotrigine: pharmacokinetic or pharmacodynamic interaction? Epilepsia. 39:2 (1998) BIALER, M. (1993) - Comparative pharmacokinetics of the newer antiepileptic drugs. Epilepsy Res. 24:6 (1993) BIALER, M. (2002) - New Antiepileptic Drugs Currently in Clinical Trials: Is There a Strategy in Their Development? Ther. Drug Monit. 24 (2002) BIALER, M. [et al.] (2002) - Progress report on new antiepileptic drugs : a summary of the Sixth Eilat Conference (EILAT VI). Epilepsy Res. 51 (2002) BLAISE, F.D.; BOURGEOIS, M.D. (2000) - Pharmacokinetic properties of current antiepileptic drugs: what improvements are needed? Neurology. 55: suppl. 3 (2000) S11-S16. BOROWICZ, KK. [et al.] (2000) - Low propensity of conventional antiepileptic drugs for interaction with felbamate against maximal electroshock-induced seizures in mice. J. Neural. Transm. 107 (2000) BOROWICZ, K.K. [et al.] (2002) - Effect of Gabapentin on the Anticonvulsivant Activity Of Antiepileptic Drugs against Electroconvulsions in Mice: An Isobolographic Analysis. Epilepsia. 43:Suppl. 9 (2002) VII. BIBLIOGRAFIA 149
4 BRODIE, M.J. (2001) Do we need any more antiepileptic drugs? Epilepsy Res. 45 (2001) 3-6. BURSTEIN, A.H. (1995) - Evaluation of new drugs: Lamotrigine. Pharmacotherapy. 15:2 (1995) CASTEL-BRANCO, M.M. [et al.] (2003) - Anticonvulsant profile of lamotrigine in rats following a single intraperitoneal dose. J. Veterinary Pharmacol. Ther. Aug. 26:Suppl. 1 (2003) CASTEL BRANCO, M.M. (2002) - Caracterização neurofarmacocinética da lamotrigina em ratos. Coimbra. Laboratório de Farmacologia; Faculdade de Farmácia, Universidade de Coimbra, 2003.Tese de doutoramento. CLEMENS, B.; MÉNES, A.; NAGY, Z. (2004) Objective assessment of neurotoxicity while shifting from carbamazepine to oxcarbazepine. Acta Neurol. Scand. 109 (2004) CZUCZWAR, S.J.; BOROWICZ K.K. (2002) Polytherapy in epilepsy: the experimental evidence. Epilepsy Res. 52 (2002) DALBY, N.O.; NIELSON, E.B. (1997) - Comparison of the preclinical anticonvulsant profiles of Tiagabine, Lamotrigine, Gabapentin and Vigabatrin. Epilepsy Res. 28 (1997) DE SARRO, G. [et al.] (2001) - Influence or retigabine on the anticonvulsant activity of some antiepileptic drugs against audiogenic seizures in DBA/2 mice. Nauny-Schmiedeberg s Arch. Pharmacol. 363 (2001) DECKERS, C.L.P. [et al.] (2000) - Selection of antiepileptic drug polytherapy based on mechanisms of action: the evidence reviewd. Nov. 41:11 Epilepsia. (2000) DECKERS, C.L.P. [et al.] (2002) - Current limitations of antiepileptic drug therapy: a conference review. Epilepsy Res. 53 (2002)
5 DIAS, M.S. (1992) Epilepsia: Considerações sobre a doença e o seu tratamento. Farmácia Port.76:7/8(1992) DICHTER, M.A.; BRODIE, M.J. (1996) - Drug Therapy: New Antiepileptic drugs. N. Engl. J. Med. Jun. 334:24 (1996) DREIFUSS, F.E. (1997) - Classification of Epileptic Seizures. In ENGEL, J.; PEDLEY, T.A. ed. lit. - Epilepsy: A Comprehensive Textbook. Philadelphia: Lippincott-Raven Publishers, Raven Publishers, Vol. 1, chapter 44 (1997) ELWES, R.D.C.; BINNIE, C.D. (1996) - Clinical Pharmacokinetics of Newer Antiepileptic Drugs: Lamotrigine, Vigabatrin; Gabapentin and Oxcarbazepine. Clin. Pharmacokinet. Jun. 30:6 (1996) ENGEL, J.J.; PEDLEY, T.A. (1997) - Introduction: What is Epilepsy? In ENGEL, J.; PEDLEY,T.A. ed. lit. - Epilepsy: A Comprehensive Textbook. Philadelphia: Lippincott-Raven Publishers. Vol. 1: Chapter 1 (1997) 1-7. ESTEVES, A.; GARRETT, C. (2001) - Antiepilépicos. In OSSWALD, W.; GUIMARÃES, S. Terapêutica Medicamentosa e suas Bases Farmacológicas. 4ªed.Porto: Porto Editora, (2001) Cap.18: p FERRENDELLI, J.A. (2001) - Concerns with antiepileptic drug initiation: safety, tolerability and efficacy. Epilepsia. 42:Suppl. 4 (2001) FERRENDELLI, J.A. (1999) - Pharmacology of Antiepileptic Drug Polypharmacy. Epilepsia. 40:Suppl. 5 (1999) S81-S83. FERRENDELLI, J.A. (1995) - Relating pharmacology to clinical practice: The pharmacologic basis of rational polypharmacy. Neurology. 45: Suppl. 2 (1995) S12-S16. FILIPE, C.N. (1997) Mecanismos básicos das epilepsias. Rev Port Pedopsiq. 12 (1997) VII. BIBLIOGRAFIA 151
6 FIRMINO, H.; MARQUES, R. (1991) - Aspectos psicossociais do Doente epiléptico. Médice. 9 (1991) FITTON, A.; GOA, K.L. (1995) - Lamotrigine. An update of its pharmacology and therapeutic use in epilepsy. Drugs. 50:4 (1995) GESSNER, P.K. (1995) - Isobolographic analysis of interactions: an update on applications and utility. Toxicology. 105 (1995) GILMAN, J.T. (1995) - Lamotrigine: an antiepileptic agent for the treatment of partial seizures. Ann. Pharmacother. 29 (1995) GIL-NAGEL, A. (2003) Review of new antiepileptic drugs as initial therapy. Epilepsia. 44 (Suppl. 4) (2003) GOA, K.L.; ROSS, S.R.; CHRISP P. (1993) - Lamotrigine: a review of its pharmacological and clinical efficacy in epilepsy. Drugs. 46:1 (1993) GOODMAN, L.S. [et al.] (1958) - Comparison of maximal seizures evoked by pentylenetetrazol (metrazol) and electroshock in mice, and their modification by anticonvulsants. J. Pharmacol. Exp. Ther. 108 (1958) GRAVES, N.M.; LEPPIK, I.E. (1991) - Antiepileptic medications in development. Ann. Pharmacother. 25 (1991) GUBERMAN, A. (1998) - Monotherapy or polytherapy for Epilepsy? Can. J. Neurol. Sci. 25:Suppl. 4 (1998) S3-S8. HACHAD, H.; RAGUENEAU-MAJLESSI, I.; LEVY, R.H. (2002) - New Antiepileptic Drugs: Review on Drug Interactions. Ther. Drug. Monit. 24:1 (2002) HULSMAN, J. A. R. J. (1995) Effects of felbamate on the pharmacokinetics of oxcarbazepine. Clin. Pharmacol. Ther. 58 (1995)
7 KALIS, M.M.; HUFF, N.A. (2001) - Oxcarbazepine, an antiepileptic agent. Clin. Ther. 23: 5 (2001) KÄLVIÄINEN, R.; KERÄNEN, T.; RIEKKINEN, SR P.J. (1993) - Place of the Newer Antiepileptic Drugs in the Tratment of epilepsy. Drugs. 46:6 (1993) KUBOVA, H.; MARES, P. (1993) - Anticonvulsant action of Oxcarbazepine, Hydroxycarbazepine, and Carbazepine against metrazol-induced motor seizures in developing rats. Epilepsia. 34:1 (1993) KWAN, P.; BRODIE, M.J. (2000) Epilepsy after the first drug fails: substitution or add-on? 9 Epilepsy Quarterly. (2000) KWAN, P. (2001) - Management of Patients with Newly Diagnosed Epilepsy. Epilepsy Quarterly. 9:2 (2001) LAFFAN, R.J.; SWINYARD, E.A.; GOODMAN, L.S. (1957) - Stimulus intensity, maximal electroshock seizures, and potency of anticonvulsants in rats. Arch. Int. Pharmacodyn. Ther. 111 (1957) LEACH, J.P. (2000) Antiepileptic drugs: safety in numbers? Seizure. 9 (2000) LEPPIK, I. E. (2000) - Monotherapy and polypharmacy. Neurology 55: Suppl. 3 (2000) S25-S29. LÖSCHER, W.; FASSBENDER, C.P,; NOLTING, B. (1991) - The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsivante drugs. II. Maximal Electroshock Seizure Models. Epilepsy Res. 8 (1991) LÖSCHER, W.; SCHMIDT, D. (1994) - Strategies in antiepileptic drug development: is rational drug design superior to random screening and structural variation? Epilepsy Res. 17 (1994) LÖSCHER, W.; SCHMIDT, D. (1998) - Which animals models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations. Epilepsy Res. 2 (1998) VII. BIBLIOGRAFIA 153
8 LÖSCHER, W. (1998) - New visions in the pharmacology of anticonvulsion. Eur. J. Pharmacol. 342 (1998) LÖSCHER, W. (2002) Current status and future directions in the pharmacotherapy of epilepsy. Trends Pharmacol. Sci. 23: 3 (2002) LÖSCHER, W,; SCHMIDT, D, (2002) New horizonts in the development of antiepileptic drugs. Epilepsy Res. 50 (2002) LOWENSTEIN, D.H. (2002) Convulsões e Epilepsia. In HARRISON,T.R..- Medicina Interna. Rio de Janeiro: Mc Graw Hill; 15ª ed., Vol II chapter 360: p LUSZCZKI, J.J. [et al.] (2003a) - Interactions Between Oxcarbazepine and Conventional Antiepileptic Drugs in the Maximal Electroshock Test in Mice: An Isobolographic Analysis. Epilepsia. 44:4 (2003a) LUSZCZKI, J.J. [et al.] (2003b) - Interactions of Lamotrigine with Topiramate and First-generation Antiepileptic Drugs in the Maximal Electroshock Test in Mice: An Isobolographic Analysis. Epilepsia. 44:8 (2003b) LUSZCZKI, J.J. [et al.] (2003c) - Interactions of Tiagabine with some antiepileptics in the maximal electroshock in mice. Pharmacol. Biochem. Behav. 75 (2003c) LUSZCZKI, J.J.; CZUCZWAR, S.J. (2003d) - Isobolographic and subthreshold methods in the detection of interactions between oxcarbazepine and conventional antiepileptics - a comparative study. Epilepsy Res. 56 (2003d) LUSZCZKI, J.J.; CZUCZWAR, S.J. (2004) - Isobolographic profile of interactions between tiagabine and gabapentin: a preclinical study. Naunyn- Schmiedeberg s Arch Pharmacol. 369 (2004) MACHADO, S.G.; ROBINSON, G.A. (1994) - A direct, general approach based on isobolograms for assessing the joint of drugs in pre-clinical experiments. Stats. Med. 13 (1994)
9 MATAR, K.M. [et al.] (1999) - Effect of valproic acid on the pharmacokinetic profile of Oxcarbazepine in the rat. Pharm. Acta Helv. 73 (1999) MAY, T.W.; KORN-MERKER, E.; RAMBECK, B. (2003) - Clinical Pharmacokinetics of Oxcarbazepine. Clin. Pharmacokinet. 42:12 (2003) MCAULEY, J. [et al.] (2002) - Newer Therapies in the Drug Treatment of Epilepsy. Ann. Pharmacother. Jan. 36 (2002) MCLEAN, M.J. (1994) - Oxcarbazepine: mechanisms of action. Epilepsia. 35: Suppl. 3 (1994) S5-S9. MILLER A.A. [et al.] (1986) - Pharmacological studies on Lamotrigine, a novel potencial antiepileptic drug: I. Anticonvulsant profile in mice and rats. Epilepsia. 27:5 (1986) MILLER, A.A. [et al.] (1986a) - Lamotrigine. In MELDRUM, B.L.; PORTER, R.J., ed. Lit. - Currents problems in epilepsy. 4-New antiepileptic drugs. London: John Libbey & Co., 1986.Chapter 12:p NATSCH, S. [et al.] (1997) - Newer Anticonvulsants Drugs: role of paharmacology, drug interactions and adverse reactions in drug choice. Drug Saf. Oct. 17:4 (1997) NOVACK, G.D.; STARK, L.G.; PETERSON,S. (1978) - Anticonvulsant effects of Bezhydryl Piperazines on Maximal Electroshock seizures in Rats. J. Pharm. Exp. Ther. 208:3 (1978) PASCHOA, O.E.D. (1997) - Seizure patterns in Kindling and Cortical Stimulation models of experimental epilepsy. Brain Res. 770 (1997) PATSALOS, P.N.; DUNCAN, J.S. (1993) - Antiepileptic Drugs: A Review of Clinically Significant Drug Interactions. Drug Saf. 9:3 (1993) PATSALOS, P.N.; SANDER, J.W.A.S. (1994) - Newer Antiepileptic Drugs: Towards an improved Risk-Benefit Ratio. Drug Saf. 11:1 (1994) VII. BIBLIOGRAFIA 155
10 PATSALOS P.N. [et al.] (2002) - The importance of drug interactions in epilepsy therapy. Epilepsia. 43:4 (2002) PELLOCK, J.M. (2000) - Treatment of Epilepsy in the New Millennium. Pharmacoterapy. 20:8 Pt. 2 (2000) 129S-138S. PERUCCA E. (2002) - Marketed new antiepileptic drugs: are they better than old-generation agents? Ther. Drug Monit. 24 (2002) PERUCCA E. (2002) Overtreatment in epilepsy: adverse consequences and mechanisms. Epilepsy Res. 52 (2002) PERUCCA E. (1995) - Pharmacological principles as a basis for polytherapy. Acta Neurol. Scand. Suppl. 162 (1995) PERUCCA E. (1996) - The New Generation Antiepileptic drugs: advantages and disadvantages. Br. J. Clin. Pharmacol. 42 (1996) Rambeck, B.; Specht, U.; Wolf, P. (1996) - Pharmacokinetic Interactions of New Antiepileptic Drugs. Clin. Pharmacokinet. Oct. 31:4 (1996) Rambeck, B.; Wolf, P. (1993) - Lamotrigine clinical pharmacokinetics. Clin. Pharmacokinet. 25:6 (1993) RATAUD, J. [et al.] (1994) - Comparative study of voltage-sensitive sodium channel blockers in focal ischaemia and electric convulsions in rodents. Neuros. Letters. 172 (1994) RIVA, R. [et al.] (1996) - Pharmacokinetic Interactions between Antiepileptic Drugs. Clin. Pharmacokinet. Dec. 31:6 (1996) ROKS, G. [et al.] (1999) - Effects of Polytherapy Compared With Monotherapy in Antiepileptics Drugs: An Animal Study. J. Pharmacol. Exp. Ther. 288 (1999) SABERS, A.; GRAM, L. (2000) - Newer Anticonvulsants: comparative review of drug interactions and adverse efects. Drugs. Jul. 60:1 (2000)
11 SMITH, P.E.M. (2001) Clinical recommendations for oxcarbazepine. Seizure. 10 (2001) SCHMIDT, D.; GRAM, L. (1995) Monotherapy versus Polytherapy in Epilepsy. CNS Drugs. 3:3 (1995) SCHMIDT, D. [et al.] (2001) Recommendations on the clinical use of oxcarbazepine in the treatment of epilepsy: a consensus view. Acta Neurol. Scand. 104 (2001) SCHMIDT, D.; ELGER, C.; HOLMES, G.L. (2002) Pharmacological overtreatment in epilepsy. Mechanisms and management. Epilepsy Res. 52 (2002a) SCHMIDT, D. (2002) Strategies to prevent overtreatment with antiepileptic drugs in patients with epilepsy. Epilepsy Res. 52 (2002b) SCHMUTZ, M. [et al.] (1994) - Oxcarbazepine: preclinical anticonvulsant profile and putative mechanisms of action. Epilepsia. 35 Suppl. 5 (1994) S SCHWABE, S. (1994) Oxcarbazepine: clinical development program. Epilepsia. 35: Suppl. 5 (1994) S51-S53. SCHWINGHAMMER, T. L.; KROBOTH P.D. (1988) Basic concepts in pharmacodynamic modelling. J. Clin. Pharmacol. 28 (1988) STEPHEN, L.J., BRODIE, M.J. (2002) Seizure freedom with more than one antiepileptic drug. Seizure. 11 (2002) STEINHOFF, B.J. [et al.] (2003) - The ideal characteristics of antiepileptic therapy: an overview of old and new AEDs. Acta Neurol. Scand. 107 (2003) SWIADER, M. [et al.] (2000) - Interaction of topiramate with conventional antiepileptic drugs in mice. Eur. J. Pharmacol. Jun. 30, 399:1 (2000) SWINYARD, E.A.; WOODHEAD, J.H.; WOLF, H.H. (1989) - Use of isobolograms in predicting drug interactions. In: PITLICK W, ed. VII. BIBLIOGRAFIA 157
12 Antiepileptic Drug Interactions. Bethesda, MD: National Institute of Health. (1989). SWINYARD, E.A.; KUPFERBERG, H.J. (1985) - Antiepileptic drugs: detection, quantification, and evaluation. Federation Proc. 44:10 (1985) 1-5. TALLARIDA, R.J.; RAFFA, R.B. (1996) - Testing for synergism over a range of fixed ratio drug combinations: replacing the isobologram. Life Sci. 58:2 (1996) TALLARIDA, R.J.; [et al.] (1999) Response surface analysis of synergism between morphine and clonidine. J. Pharm. Exp. Ther. 289 (1999) TALLARIDA, R.J. (2001) - Drug synergism: its detection and applications. J. Pharm. Exp. Ther. 298 (2001) TALLARIDA, R.J. (2002) - The interaction index: a measure of drug synergism. Pain. 98 (2002) TECOMA, E.S. (1999) Oxcarbazepine. Epilepsia. 40: Suppl.5 (1999) S37- S46. THOMSON, A.H.; BRODIE, M.J. (1992) - Pharmacokinetic Optimisation of Anticonvulsant Therapy. Clin. Pharmacokinet. 23:3 (1992) TOMAN, J.E.P.; SWINYARD, E.A.; GOODMAN, L.S. (1946) - Properties of maximal seizures, and their alteration by anticonvulsant drugs and other agents. J. Neurophysiol. 9 (1946) TRACY, A.; GLAUSSER, M.D. (2001) - Oxcarbazepine in the treatment of epilepsy. Pharmacoterapy. 21:8 (2001) UPTON, N. (1994) - Mechanisms of action of new antiepileptic drugs: rational design and serendipitous findings. TIPS. Dec. 15 (1994) VAN OPSTAL, J. M. [et al.] (2004) Severe overdosage with the antiepileptic drug oxcarbazepine. Br. J. Clin. Pharmacol. 58:3 (2004)
13 URE, J.A.; PERASSOLO. M.; (2000) - Update on the pathophysiology of the epilepsies - review article. J. Neurolog. Sci. 177 (2000) WAMIL, A.W. [et al.] (1994) - Effects of oxcarbazepine and 10- hydroxycarmazepine on action potencial firing and generalized seizures. Eur. J. Pharmacol. 271 (1994) WHITE, H.S. (1999) - Comparative Anticonvulsant and Mechanistic Profile of the Established and Newer Antiepileptic Drugs. Epilepsia. 40 Suppl.5 (1999) S2-S10. WHITE, H.S. (2003) - Preclinical Development of Antiepileptic Drugs: Past, Present and Future directions. Epilepsia. 44 Suppl. 7 (2003) 2-8. WOLF, P. (1997). International Classification of the Epilepsies. In ENGEL, J.; PEDLEY,T.A. ed. lit. - Epilepsy: A Comprehensive Textbook. Philadelphia: Lippincott-Raven Publishers. (1997) Vol. 1 Chapter 68: p ZONA, C. [et al.]. (2002) - Neocortical potassium corrents are enhanced by the antiepileptic drug Lamotrigine. Epilepsia. 43:7 (2002) VII. BIBLIOGRAFIA 159
Isobolographic analysis of interactions among losigamone analog AO-620 and two conventional antiepileptic drugs
Pharmacological Reports 2005, 57, 236 240 ISSN 1734-1140 Copyright 2005 by Institute of Pharmacology Polish Academy of Sciences Short communication Isobolographic analysis of interactions among losigamone
More informationTHE MAXIMAL ELECTROSHOCK SEIZURE (MES) MODEL IN THE PRECLINICAL ASSESSMENT OF POTENTIAL NEW ANTIEPILEPTIC DRUGS
Methods Find Exp Clin Pharmacol 2009, 31(2): 101-106 Copyright 2009 Prous Science, S.A.U. or its licensors. All rights reserved. CCC: 0379-0355/2009 DOI: 10.1358/mf.2009.31.2.1338414 REVIEW ARTICLE THE
More information, Jarogniew J. Łuszczki
Wydawnictwo UR 2017 ISSN 2544-1361 (online); ISSN 2544-2406 doi: 10.15584/ejcem.2017.4.1 303 http://www.ejcem.ur.edu.pl/en/ European Journal of Clinical and Experimental Medicine Eur J Clin Exp Med 2017;
More informationAdvances in Medical Sciences Vol. 54(1) 2009 pp DOI: /v Medical University of Bialystok, Poland
Advances in Medical Sciences Vol. 54(1) 2009 pp 75-81 DOI: 10.2478/v10039-009-0006-7 Medical University of Bialystok, Poland Interaction of tiagabine with valproate in the mouse pentylenetetrazole-induced
More informationDifficult to treat childhood epilepsy: Lessons from clinical case scenario
Difficult to treat childhood epilepsy: Lessons from clinical case scenario Surachai Likasitwattanakul, M.D. Department of Pediatrics Faculty of Medicine, Siriraj Hospital Natural history of Epilepsy Untreated
More informationInteractions of retigabine with topiramate in the mouse tonic-clonic seizure model and chimney test an isobolographic analysis
ORIGINAL ARTICLE Journal of Pre-Clinical and Clinical Research, 2017, Vol 11, No 1, 61-65 www.jpccr.eu Interactions of retigabine with topiramate in the mouse tonic-clonic seizure model and chimney test
More informationEvidence for Efficacy of Combination of Antiepileptic Drugs in Treatment of Epilepsy
Elmer ress Review J Neurol Res. 2015;5(6):267-276 Evidence for Efficacy of Combination of Antiepileptic Drugs in Treatment of Epilepsy Ehsan M. Sarhan a, b, Matthew C. Walker a, Caroline Selai a Abstract
More informationMONOTHERAPY OR POLYTHERAPY FOR CHILDHOOD EPILEPSIES?
MONOTHERAPY OR POLYTHERAPY FOR CHILDHOOD EPILEPSIES? Oluwaseun Egunsola 1, Helen M Sammons 1 and William P Whitehouse 2,3 1Academic Division of Child Health, University of Nottingham, Derbyshire Children
More informationThe New England Journal of Medicine EARLY IDENTIFICATION OF REFRACTORY EPILEPSY. Patients
EARLY IDENTIFICATION OF REFRACTORY EPILEPSY PATRICK KWAN, M.D., AND MARTIN J. BRODIE, M.D. ABSTRACT Background More than 30 percent of patients with epilepsy have inadequate control of seizures with drug
More informationDiscovery of Antiepileptic Drugs
Neurotherapeutics: The Journal of the American Society for Experimental NeuroTherapeutics Discovery of Antiepileptic Drugs Misty Smith, Karen S. Wilcox, and H. Steve White Anticonvulsant Drug Development
More informationInternational Journal of Innovative Pharmaceutical Sciences and Research
International Journal of Innovative Pharmaceutical Sciences and Research www.ijipsr.com DETERMINATION OF PROTECTIVE INDICES OF PHENYTOIN AND SODIUM VALPROATE USING MOUSE BEAM WALKING ASSAY FOR MOTOR COORDINATION
More informationMedications for Epilepsy What I Need to Know
Medications for Epilepsy What I Need to Know Safiya Ladak, BSc.Phm. Toronto Western Hospital, UHN Clinical Pharmacist, Neurology and Neurosurgery June 4, 2016 Learning Objectives Treatment options for
More informationTherapeutic strategies in the choice of antiepileptic drugs
Acta neurol. belg., 2002, 102, 6-10 Original articles Therapeutic strategies in the choice of antiepileptic drugs V. DE BORCHGRAVE, V. DELVAUX, M. DE TOURCHANINOFF, J.M. DUBRU, S. GHARIANI, Th. GRISAR,
More informationMONOTHERAPY IS PREferred
Monotherapy in Epilepsy Role of the Newer Antiepileptic Drugs Blanca Vazquez, MD NEUROLOGICAL REVIEW Background: Monotherapy is the goal for pharmacological treatment of epilepsy. Well-controlled trials
More informationConcomitant administration of rifampicin and oxcarbazepine results in a significant decrease of the active MHD metabolite of oxcarbazepine
Zurich Open Repository and Archive University of Zurich Main Library Strickhofstrasse 39 CH-8057 Zurich www.zora.uzh.ch Year: 2016 Concomitant administration of rifampicin and oxcarbazepine results in
More informationCan drug resistance in epilepsy be minimized? Challenging commonly held beliefs
Global care of patients with drug resistant epilepsy Epileptic Disord 2005; 7 (Suppl. 1): S14-S21 Can drug resistance in epilepsy be minimized? Challenging commonly held beliefs Emilio Perucca Clinical
More informationTopamax and lamictal interactions
Interactions of lamotrigine with topiramate and first-generation antiepileptic drugs in the maximal electroshock test in mice: an isobolographic analysis. Luszczki JJ( 1), Czuczwar M, Kis J, Krysa J, Pasztelan
More informationANTIEPILEPTIC DRUGS FIFTH EDITION. Editors. RENE H. LEVY, PhD
ANTIEPILEPTIC DRUGS FIFTH EDITION Editors RENE H. LEVY, PhD Professor and Chair, Department of Pharmaceutics Professor of Neurological Surgery University ofwashington Schools of Pharmacy and Medicine Seattle,
More informationTRAMADOL, A CENTRALLY ACTING OPIOID : ANTICONVULSANT EFFECT AGAINST MAXIMAL ELECTROSHOCK SEIZURE IN MICE
Indian J Physiol Pharmacol 1998; 42 (3) : 407-411 TRAMADOL, A CENTRALLY ACTING OPIOID : ANTICONVULSANT EFFECT AGAINST MAXIMAL ELECTROSHOCK SEIZURE IN MICE ANSHU MANOCHA, KRISHNA K. SHARMA* AND PRAMOD K.
More informationMariusz Œwi¹der 1, Hubert KuŸniar 1, Zdzis³aw Kleinrok 1, Stanis³aw J. Czuczwar 2,3,#
Copyright 23 by Institute of Pharmacology Polish Academy of Sciences Polish Journal of Pharmacology Pol. J. Pharmacol., 23, 55, 13 17 ISSN 123-62 SHORT COMMUNICATION INFLUENCE OF LY 3164, AN AMPA/KAINATE
More informationThe ideal pharmacokinetic properties of an antiepileptic drug: how close does levetiracetam come?
Treatment of Epilepsy: Focus on Levetiracetam Epileptic Disord 2003; 5 (Suppl 1): S17 S26 The ideal pharmacokinetic properties of an antiepileptic drug: how close does levetiracetam come? Emilio Perucca
More informationRational Polytherapy with Antiepileptic Drugs
Pharmaceuticals 2010, 3, 2362-2379; doi:10.3390/ph3082362 Review OPEN ACCESS pharmaceuticals ISSN 1424-8247 www.mdpi.com/journal/pharmaceuticals Rational Polytherapy with Antiepileptic Drugs Jong Woo Lee
More informationWhen choosing an antiepileptic ... PRESENTATION... Pharmacokinetics of the New Antiepileptic Drugs. Based on a presentation by Barry E.
... PRESENTATION... Pharmacokinetics of the New Antiepileptic Drugs Based on a presentation by Barry E. Gidal, PharmD Presentation Summary A physician s choice of an antiepileptic drug (AED) usually depends
More informationIs a hypothermic effect of LY , valproate and phenobarbital evident in mice?
270 Świąder MJ, et al. Roczniki Akademii Medycznej w Białymstoku Vol. 49, 2004 Annales Academiae Medicae Bialostocensis Is a hypothermic effect of LY 300164, valproate and phenobarbital evident in mice?
More informationThe Epilepsy Prescriber s Guide to Antiepileptic Drugs
The Epilepsy Prescriber s Guide to Antiepileptic Drugs The Epilepsy Prescriber s Guide to Antiepileptic Drugs Philip N. Patsalos FRCPath, PhD Professor of Clinical Pharmacology and Consultant Clinical
More informationNew Medicines Profile
New Medicines Profile February 2010 Issue No. 10/02 Eslicarbazepine Concise evaluated information to support the managed entry of new medicines in the NHS Brand Name, (Manufacturer): Zebinix (Eisai Limited)
More informationSeizure 20 (2011) Contents lists available at ScienceDirect. Seizure. journal homepage:
Seizure 20 (2011) 359 368 Contents lists available at ScienceDirect Seizure journal homepage: www.elsevier.com/locate/yseiz Review Critical review of current animal models of and epilepsy used in the discovery
More informationeslicarbazepine acetate 800mg tablet (Zebinix) SMC No. (592/09) Eisai Ltd
eslicarbazepine acetate 800mg tablet (Zebinix) SMC No. (592/09) Eisai Ltd 8 October 2010 The Scottish Medicines Consortium (SMC) has completed its assessment of the above product and advises NHS Boards
More informationSeletracetam (UCB 44212)
Neurotherapeutics: The Journal of the American Society for Experimental NeuroTherapeutics Seletracetam (UCB 44212) Barbara Bennett,* Alain Matagne, Philippe Michel, Michèle Leonard, Miranda Cornet, Marie-Anne
More informationEpilepsy is a very individualized
... PRESENTATION... Treatment of Epilepsy in 3 Specialized Populations Based on a presentation by Ilo E. Leppik, MD Presentation Summary When discussing the treatment of epilepsy, targeted populations
More informationDisclosure. Learning Objectives
Linda D. Leary, M.D. Associate Clinical Professor of Pediatrics & Neurology South Texas Comprehensive Epilepsy Center UT Health Science Center San Antonio Disclosure Linda D. Leary, M.D. discloses the
More informationMechanisms of Action of Antiepileptic Drugs
Mechanisms of Action of Antiepileptic Drugs Piotr Czapiński 1, Barbara Blaszczyk 2, Stanislaw J. Czuczwar 3,4,* Current Topics in Medicinal Chemistry 2005, 5, 3-14 3 1 Center for Treatment of Epilepsy
More informationThe Effectiveness of Monotheraby in Epileptic Sudanese Patients
The Effectiveness of Monotheraby in Epileptic Sudanese Patients Amel Elmahi Mohamed (1) Sawsan A Aldeaf (1) Alsadig Gassoum (1) Alnada Abdalla Mohamed (2) Mohamed A Arbab (1,3) and Alamin Ebrahim (2) Abstract
More informationLacosamide (Vimpat) for partial-onset epilepsy monotherapy. December 2011
Lacosamide (Vimpat) for partial-onset epilepsy monotherapy This technology summary is based on information available at the time of research and a limited literature search. It is not intended to be a
More informationGabapentin synergistically interacts with topiramate in the mouse maximal electroshock seizure model: an isobolographic analysis
Pharmacological Reports 2006, 58, 944 954 ISSN 1734-1140 Copyright 2006 by Institute of Pharmacology Polish Academy of Sciences Short communication Gabapentin synergistically interacts with topiramate
More informationInteractions of Mexiletine with Novel Antiepileptic Drugs in the Maximal Electroshock Test in Mice: An Isobolographic Analysis
Neurochemical Research (2018) 43:1887 1896 https://doi.org/10.1007/s11064-018-2606-8 ORIGINAL PAPER Interactions of Mexiletine with Novel Antiepileptic Drugs in the Maximal Electroshock Test in Mice: An
More informationErnie Somerville Prince of Wales Hospital EPILEPSY
Ernie Somerville Prince of Wales Hospital EPILEPSY Overview Classification New and old anti-epileptic drugs (AEDs) Neuropsychiatric side-effects Limbic encephalitis Non-drug therapies Therapeutic wishlist
More informationJournal of Chemical and Pharmaceutical Research
Available online www.jocpr.com Journal of Chemical and Pharmaceutical Research ISSN No: 0975-7384 CODEN(USA): JCPRC5 J. Chem. Pharm. Res., 2011, 3(5):468-472 Study on the anticonvulsant activity of Pentazocine
More informationVENKATESH NAGARADDI, MD
- 1 - VENKATESH NAGARADDI, MD 7777 Forest Lane, C-650 Dallas, Texas 75230 vnagaraddi@hotmail.com (972) 566 8579 NEUROLOGY/EPILEPTOLOGY North Dallas Epilepsy Sep, 16 present Director of Neurodiagnostics
More information2018 American Academy of Neurology
Practice Guideline Update Efficacy and Tolerability of the New Antiepileptic Drugs I: Treatment of New-Onset Epilepsy Report by: Guideline Development, Dissemination, and Implementation Subcommittee of
More informationIntroduction to seizures and epilepsy
Introduction to seizures and epilepsy Selim R. Benbadis, M.D. Professor Departments of Neurology & Neurosurgery Director, Comprehensive Epilepsy Program Symptomatic seizures Head injury (trauma) Stroke
More informationZonisamide for migraine prophylaxis in refractory patients
Thomas Jefferson University Jefferson Digital Commons Department of Neurology Faculty Papers Department of Neurology March 2006 Zonisamide for migraine prophylaxis in refractory patients Avi Ashkenazi
More informationMonotherapy and polytherapy in Paediatric seizures: A prospective, observational study in a tertiary care teaching hospital
Original Research Article Monotherapy and polytherapy in Paediatric seizures: A prospective, observational study in a tertiary care teaching hospital Henry Daniel Raj T 1, Sylvia A 2*, Chidambaranathan
More informationTrends in Utilization of Antiepileptic Drugs Among Pediatric Patients in a Tertiary Care Hospital
Current Neurobiology 2011; 2 (2): 117123 Trends in Utilization of Antiepileptic Drugs Among Pediatric Patients in a Tertiary Care Hospital Maity N and Niveditha Gangadhar Department of Pharmacology, M.S
More informationDisclosures. Objectives 2/16/2015. Women with Epilepsy: Seizures in Pregnancy and Maternal/Fetal Outcomes
Women with Epilepsy: Seizures in Pregnancy and Maternal/Fetal Outcomes 40 th Annual Progress in OBGYN February 19, 2015 Jennifer L. DeWolfe, DO Associate Professor UAB Epilepsy Center Director, BVAMC Sleep
More information2018 American Academy of Neurology
Practice Guideline Update Efficacy and Tolerability of the New Antiepileptic Drugs II: Treatment-Resistant Epilepsy Report by: Guideline Development, Dissemination, and Implementation Subcommittee of the
More informationKeywords: treatment; epilepsy; population based cohort Institute of Neurology, University College London, London WC1N 3BG, UK
632 Institute of Neurology, University College London, London WC1N 3BG, UK S D Lhatoo JWASSander S D Shorvon Correspondence to: Professor J W Sander, Department of Clinical and Experimental Epilepsy, Institute
More informationCost-effective analysis of dual therapy in epilepsy, a study from India
Neurology Asia 2011; 16(4) : 309 314 Cost-effective analysis of dual therapy in epilepsy, a study from India 1 Sarita Goyal MD (Pharmacology), 2 DC Dhasmana MD (Pharmacology), 3 Deepak Goel MD DM (Neurology),
More informationEvidence for a rapid action of levetiracetam compared to topiramate in refractory partial epilepsy
Seizure (2006) 15, 112 116 www.elsevier.com/locate/yseiz Evidence for a rapid action of levetiracetam compared to topiramate in refractory partial epilepsy Luigi M. Specchio a,e, *, Giovanni Boero b,e,
More informationRationale and Evidence for the Use of Oxcarbazepine in Neuropathic Pain
Vol. 25 No. 5S May 2003 Journal of Pain and Symptom Management S31 Neuropathic Pain: From Mechanisms to Treatment Strategies Rationale and Evidence for the Use of Oxcarbazepine in Neuropathic Pain Enrique
More informationPROCEEDINGS PHARMACOLOGIC TREATMENT CONSIDERATIONS * Dennis J. Dlugos, MD ABSTRACT
PHARMACOLOGIC TREATMENT CONSIDERATIONS * Dennis J. Dlugos, MD ABSTRACT A number of traditional and newer antiepileptic drugs (AEDs) are used for the initial treatment of new-onset epilepsy. The decision-making
More informationCombined Ketogenic Diet and Vagus Nerve Stimulation: Rational Polytherapy?
Epilepsia, 48(1):77 81, 2007 Blackwell Publishing, Inc. C 2007 International League Against Epilepsy Combined Ketogenic Diet and Vagus Nerve Stimulation: Rational Polytherapy? Eric H. Kossoff, Paula L.
More informationSafety and Efficacy of Oxcarbazepine: Results of Randomized, Double-Blind Trials
Safety and Efficacy of Oxcarbazepine: Results of Randomized, Double-Blind Trials Ahmad Beydoun, M.D. Oxcarbazepine is approved as monotherapy and adjunctive therapy for partial seizures with and without
More informationChanges in the Disposition of Oxcarbazepine and Its Metabolites during Pregnancy and the Puerperium
Epilepsia, 47(3):4 9, 26 Blackwell Publishing, Inc. C 26 International League Against Epilepsy Changes in the Disposition of Oxcarbazepine and Its Metabolites during Pregnancy and the Puerperium Iolanda
More informationTHE TREATMENT GAP AND POSSIBLE THERAPIES OF EPILEPSY IN SUB- SAHARAN AFRICA
THE TREATMENT GAP AND POSSIBLE THERAPIES OF EPILEPSY IN SUB- SAHARAN AFRICA DR A.O. CHARWAY-FELLI, MD, PhD NEUROLOGIST 37 MILITARY HOSPITAL, ACCRA, GHANA SECRETARY-GENERAL AFRICAN ACADEMY OF NEUROLOGY
More informationCharacterization of epilepsy with onset after 60 years of age
http://dx.doi.org/10.1590/1809-98232016019.150074 343 Characterization of epilepsy with onset after 60 years of age Original Articles Igor Silvestre Bruscky 1 Ricardo André Amorim Leite 1 Carolina da Cunha
More informationEpilepsies of Childhood: An Over-view of Treatment 2 nd October 2018
Epilepsies of Childhood: An Over-view of Treatment 2 nd October 2018 Dr Sophia Varadkar MRCPI, PhD Consultant Paediatric Neurologist and Honorary Senior Lecturer Great Ormond Street Hospital for Children
More informationAN UPDATE ON ANTIEPILEPTIC AGENTS: FOCUS ON AN UPDATE ON ANTIEPILEPTIC AGENTS: FOCUS ON SECOND GENERATION TREATMENT OPTIONS
Volume 24, Issue 1 October 2008 AN UPDATE ON ANTIEPILEPTIC AGENTS: FOCUS ON SECOND GENERATION TREATMENT OPTIONS Jason Richey, Pharm.D. Candidate Epilepsy is a neurological disorder characterized by sudden
More informationOdisha, India 3 Prof & HOD,Department of Pharmacology, V. S. S.Medical College, Burla, Sambalpur, Odisha, India
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-issn: 2279-0853, p-issn: 2279-0861.Volume 15, Issue 7 Ver. VI (July. 2016), PP 65-73 www.iosrjournals.org Effect of on the Antiepileptic Action
More informationNew antiepileptic drugs
Chapter 29 New antiepileptic drugs J.W. SANDER UCL Institute of Neurology, University College London, National Hospital for Neurology and Neurosurgery, Queen Square, London, and Epilepsy Society, Chalfont
More informationThe importance of pharmacogenetics in the treatment of epilepsy
The importance of pharmacogenetics in the treatment of epilepsy Öner Süzer and Esat Eşkazan İstanbul University, Cerrahpaşa Faculty of Medicine, Department of Pharmacology and Clinical Pharmacology Introduction
More informationOptimizing Antiepileptic Drug Therapy in Refractory Epilepsy
15 Optimizing Antiepileptic Drug Therapy in Refractory Epilepsy Nicholas P. Poolos Department of Neurology and UW Regional Epilepsy Center, University of Washington, Seattle, WA, USA Introduction: When
More informationSomnolence and Sedation Were Transient Adverse Events for Most Patients Receiving Clobazam Therapy: Post Hoc Analysis of Trial OV-1012 Data
Elmer ress Short Communication J Neurol Res. 2015;5(4-5):252-256 Somnolence and Sedation Were Transient Adverse Events for Most Patients Receiving Clobazam Therapy: Post Hoc Analysis of Trial OV-1012 Data
More informationIntroduction OPEN ACCESS. Peter Martin and Jörg Fahrbach
Macedonian Journal of Medical Sciences. 2012 Mar 15; 5(1):85-89. http://dx.doi.org/10.3889/mjms.1857-5773.2011.0211 Clinical Science OPEN ACCESS Efficacy of Zonisamide Levetiracetam Comedication in Nine
More informationAntiepileptic Drugs (Anticonvulsants )
Antiepileptic Drugs (Anticonvulsants ) NEPHAR 305 Pharmaceutical Chemistry I Assist.Prof.Dr. Banu Keşanlı 1 Anticonvulsants Anticonvulsants, sometimes also called antiepileptics, belong to a diverse group
More informationEpilepsy. Seizures and Epilepsy. Buccal Midazolam vs. Rectal Diazepam for Serial Seizures. Epilepsy and Seizures 6/18/2008
Seizures and Epilepsy Paul Garcia, M.D. UCSF Epilepsy Epileptic seizure: the physical manifestation of aberrant firing of brain cells Epilepsy: the tendency to recurrent, unprovoked epileptic seizures
More informationD espite recent developments in the nonmedical
581 REVIEW New drugs for the treatment of epilepsy: a practical approach S Beyenburg, J Bauer, M Reuber... The availability of new antiepileptic drugs has broadened the spectrum of medical treatment options
More informationUpdated advice for nurses who care for patients with epilepsy
NICE BULLETIN Updated advice for nurses who care for patients with epilepsy NICE provided the content for this booklet which is independent of any company or product advertised NICE BULLETIN Updated advice
More informationNew treatment option for partial-onset seizures: efficacy and safety of lacosamide
Therapeutic Advances in Neurological Disorders Review New treatment option for partial-onset seizures: efficacy and safety of lacosamide Steve S. Chung Ther Adv Neurol Disord (2010) 3(2) 77 83 DOI: 10.1177/
More informationMonotherapy in Newly Diagnosed Epilepsy: Levetiracetam Versus Standard Anticonvulsants
Monotherapy in Newly Diagnosed Epilepsy: Levetiracetam Versus Standard Anticonvulsants Current Literature In Clinical Science KOMET: An Unblinded, Randomised, Two Parallel-Group, Stratified Trial Comparing
More informationMechanisms of action of antiepileptic drugs
Mechanisms of action of antiepileptic drugs Chapter 25 GRAEME J. SILLS Department of Molecular and Clinical Pharmacology, University of Liverpool Introduction The serendipitous discovery of the anticonvulsant
More informationDo seizures beget seizures?
Does MTLE cause progressive neurocognitive damage? Andrew Bleasel Westmead Do seizures beget seizures? The tendency of the disease is toward self-perpetuation; each attack facilitates occurrence of another
More informationPharmacological Treatment of Non-Lesional Epilepsy December 8, 2013
Pharmacological Treatment of Non-Lesional Epilepsy December 8, 2013 Michael Privitera, MD Professor of Neurology University of Cincinnati, Neuroscience Institute American Epilepsy Society Annual Meeting
More informationPRO- AND ANTIAPOPTOPIC EFFECTS OF ANTICONVULSANT DRUGS
PROGRESS IN ETIOPATHOGENESIS SEIZURES PRO- AND ANTIAPOPTOPIC EFFECTS OF ANTICONVULSANT DRUGS W³adys³aw Lasoñ Institute of Pharmacology, Polish Academy of Sciences, Smêtna 12, PL 31-343 Kraków, Poland According
More informationDeralakatte, Mangalore, India Dept of Pharmacology, Yenepoya Medical College, Yenepoya University,
International Journal of Universal Pharmacy and Bio Sciences 2(3): May-June 2013 INTERNATIONAL JOURNAL OF UNIVERSAL PHARMACY AND BIO SCIENCES Pharmaceutical Sciences Research Article!!! Received: 02-05-2013;
More informationPreliminary Evaluation of the Antiepileptic Activity of Lacosamide in Libyan Epileptic Center.
J. Pharm. Appl. Chem. 4, No. 2, 91-97 (2018) 91 Journal of Pharmaceutical and Applied Chemistry An International Journal http://dx.doi.org/10.18576/jpac/040203 Preliminary Evaluation of the Antiepileptic
More informationThere has been a history of problems with
UNDERSTANDING THE RAMIFICATIONS OF SWITCHING AMONG AEDS: WHAT ARE THE DATA? Gail D. Anderson, PhD* ABSTRACT Historically, there have been problems with generic versions of older antiepileptic drugs (AEDs),
More informationAnticonvulsants Antiseizure
Anticonvulsants Antiseizure Seizure disorders Head trauma Stroke Drugs (overdose, withdrawal) Brain tumor Encephalitis/ Meningitis High fever Hypoglycemia Hypocalcemia Hypoxia genetic factors Epileptic
More informationPredictors of Intractable Childhood Epilepsy
ORIGINAL ARTICLE Predictors of Intractable Childhood Epilepsy Muhammad Akbar Malik 1, Muhammad Haroon Hamid 2, Tahir Masood Ahmed 2 and Qurban Ali 3 ABSTRACT Objective: To determine the prognosis of seizures
More informationModified release drug delivery system for antiepileptic drug (Formulation development and evaluation).
TITLE OF THE THESIS / RESEARCH: Modified release drug delivery system for antiepileptic drug (Formulation development and evaluation). INTRODUCTION: Epilepsy is a common chronic neurological disorder characterized
More informationChildren Are Not Just Small Adults Choosing AEDs in Children
Children Are Not Just Small Adults Choosing AEDs in Children Natrujee Wiwattanadittakun, MD Neurology division, Department of Pediatrics, Chiang Mai University Hospital, Chiang Mai University 20 th July,
More informationReview of Anticonvulsant Medications: Traditional and Alternative Uses. Andrea Michel, PharmD, CACP
Review of Anticonvulsant Medications: Traditional and Alternative Uses Andrea Michel, PharmD, CACP Objectives Review epidemiology of epilepsy Classify types of seizures Discuss non-pharmacologic and pharmacologic
More informationClinical Policy: Clobazam (Onfi) Reference Number: CP.PMN.54. Line of Business: Medicaid
Clinical Policy: (Onfi) Reference Number: CP.PMN.54 Effective Date: 11/12 Last Review Date: 05/17 Line of Business: Medicaid Coding Implications Revision Log See Important Reminder at the end of this policy
More informationA Clinical Overview of the New Antiepileptic Drugs
Bahrain Medical Bulletin, Vol.28, No.3, September 2006 A Clinical Overview of the New Antiepileptic Drugs Dr. Shoaa F. Al-Shammary* Over the past decade, several new antiepileptic drugs (AEDs) have become
More informationThis is a refereed journal and all articles are professionally screened and reviewed
Advances in Environmental Biology, 5(7): 1866-1870, 2011 ISSN 1995-0756 1866 This is a refereed journal and all articles are professionally screened and reviewed ORIGINAL ARTICLE Effect of Nimodipine on
More informationARTICLES Monotherapy in adults and elderly persons
ARTICLES Monotherapy in adults and elderly persons Edward Faught, MD Address correspondence and reprint requests to Dr. Edward Faught, Department of Neurology, University of Alabama at Birmingham Epilepsy
More informationOverview: Idiopathic Generalized Epilepsies
Epilepsia, 44(Suppl. 2):2 6, 2003 Blackwell Publishing, Inc. 2003 International League Against Epilepsy Overview: Idiopathic Generalized Epilepsies Richard H. Mattson Department of Neurology, Yale University
More informationNew drugs necessity for therapeutic drug monitoring
New drugs necessity for therapeutic drug monitoring Stephan Krähenbühl Clinical Pharmacology & Toxicology University Hospital Basel kraehenbuehl@uhbs.ch Drugs suitable for TDM Narrow therapeutic range
More informationSeizure control with antiepileptic drug therapy in 517 consecutive adult outpatients at the Kork Epilepsy Centre
Original article Epileptic Disord 2012; 14 (4): 379-87 Seizure control with antiepileptic drug therapy in 517 consecutive adult outpatients at the Kork Epilepsy Centre Bernhard J Steinhoff, Anke Maren
More informationPharmaco-epidemiological and pharmaco-economic analysis of antiepileptic drugs at a tertiary level health care centre - a crosssectional
Original article: Pharmaco-epidemiological and pharmaco-economic analysis of antiepileptic drugs at a tertiary level health care centre - a crosssectional prospective study Dr. Shraddha Tatkare 1 *, Dr.
More informationWHY CHILDREN ARE DIFFERENT FROM ADULTS
XXASIM May p159-165 5/14/01 9:23 AM Page 159 NEW PHARMACOLOGICAL TREATMENTS FOR PEDIATRIC EPILEPSY Blaise F.D. Bourgeois, MD KEY POINTS Antiepileptic drugs (AEDs) are tailored to pediatric epilepsy seizure
More informationRisk of seizure recurrence after antiepileptic drug withdrawal, an Indian study
Neurology Asia 2006; 11 : 19 23 Risk of seizure recurrence after antiepileptic drug withdrawal, an Indian study Archana VERMA DM (Neurology) MD, Surendra MISRA DM (Neurology) FRCP (Edin) Department of
More informationAED Treatment Approaches. David Spencer, MD Director, OHSU Epilepsy Center Professor, Department of Neurology
AED Treatment Approaches David Spencer, MD Director, OHSU Epilepsy Center Professor, Department of Neurology Audience Response Keypads Please utilize the keypad at your table to answer questions throughout
More informationp ผศ.นพ.ร งสรรค ช ยเสว ก ล คณะแพทยศาสตร ศ ร ราชพยาบาล
Natural Course and Prognosis of Epilepsy p ผศ.นพ.ร งสรรค ช ยเสว ก ล คณะแพทยศาสตร ศ ร ราชพยาบาล Introduction Prognosis of epilepsy generally means probability of being seizure-free after starting treatment
More informationRole of rufinamide in the management of Lennox-Gastaut syndrome (childhood epileptic encephalopathy)
EXPERT OPINION Role of rufinamide in the management of Lennox-Gastaut syndrome (childhood epileptic encephalopathy) Gerhard Kluger 1 Bettina Bauer 2 1 Klinik für Neuropädiatrie und Neurologische Rehabilitation,
More informationGeneric Name (Brand Name) Available Strengths Formulary Limits. Primidone (Mysoline) 50mg, 250mg -- $
MEDICATION COVERAGE POLICY PHARMACY AND THERAPEUTICS ADVISORY COMMITTEE POLICY: Epilepsy P&T DATE: 2/15/2017 THERAPEUTIC CLASS: Neurologic Disorders REVIEW HISTORY: 2/16 LOB AFFECTED: Medi-Cal (MONTH/YEAR)
More informationRevisiting the Ketogenic Diet and Related Therapies in the Modern Era
Revisiting the Ketogenic Diet and Related Therapies in the Modern Era Heung Dong Kim M.D., Ph.D. Pediatric Epilepsy Clinic, Division of Pediatric Neurology Severance Children s Hospital Yonsei University
More informationUsing antiepileptic drugs in children: recent developments and recommendations
Using antiepileptic drugs in children: recent developments and recommendations 1 Hana Shabbi, 1 Anne Marie Scerri, 2 Doriette M Soler, 1 Janet Mifsud 1 Department of Clinical Pharmacology and Therapeutics,
More informationThe new generation of antiepileptic drugs: advantages and disadvantages
Br J Clin Pharmacoll996; 42: 531-543 The new generation of antiepileptic drugs: advantages and disadvantages EMILIO PERUCCA Clinical Pharmacology Unit, Department of Internal Medicine and Therapeutics,
More informationAn Introduction to Antiepileptic Drugs
Epilepsia, 46(Suppl. 4):31 37, 2005 Blackwell Publishing, Inc. C International League Against Epilepsy An Introduction to Antiepileptic Drugs Emilio Perucca Clinical Pharmacology Unit, Department of Internal
More information