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1 (5 ) : Downloaded from ijdld.tums.ac.ir at 6:29 IRDT on Friday March 22nd 209. :.. 30 : HDL-C LDL-C. HDL-C LDL-C. Backward (% 43/7) 44 : 6 (kg/m 2 ) (kg/m 2 ) BMI ( 42-65). /7 (/8-2/49) %95-52). HDL-C LDL-C 2/7 ( 52-56) 4 (2/24-7/) (3. 2/7. : : / / : azizi@endocrine.ac.ir : : :

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3 ( 5 ) Downloaded from ijdld.tums.ac.ir at 6:29 IRDT on Friday March 22nd 209. ±. t test (CI :%95) () HDL- (mg/dl) (mg/dl) (kg) ( ) (mg/dl) (mg/dl) LDL-C (mg/dl) C (mmhg) ( ). (OR) Backward : ).. (. HDL-C APO-B..[20] LDL-C %6 /6 % SPSS.

4 563 : : Downloaded from ijdld.tums.ac.ir at 6:29 IRDT on Friday March 22nd 209 LDL- C HDL-C..(2 ) 3 (%95 ) 8-52) (2/4-7/) 4 (3 (6-74).(P<0/03) (/04-4/50) 2/7 ( 52-56) ( ) ( ) 44 (36-55) 45 (36-58) 44 ( 36-54) ( ) 7 (63-79) 74 (66-83) 68 (6-76) ( ) 6 (55-68) 69 (65-73) 56 (52-60) () 22 (85-242) 207 (8-235) 26 (88-248) (mg/dl) 56 (06-223) 63 (3-233) 5 (02-25) (mg/dl) 42 (35-49) 39 (32-42) 42 (39-53) (mg/dl) HDL-C 35 (2-6) 33 (0-56) 37 (4-64) (mg/dl) LDL-C 33/9 30 3/9 (). (/47-4/99) 2/7 (%95 ) -4/02) /92 (0/92.(P<0/08). (%95 ) (/8-2/49) /7 ( 42-65) (P<0/005)..(4 ). ( ) -2 p-value ( ) p<0/00 44(36-56) 57( 47-64) ( ) p<0/004 69( 65-74) 68 (63-72) () p<0/00 26( 24-29) 27(24-29) (Kg/m 2 ) p<0/00 205( ) 222(96-255) (mg/dl) p<0/003 6 ( 2-230) 80(3-268) (mg/dl) p<0/00 32( 09-55) 46(22-70) (mg/dl) LDL-C p<0/6 39( 32-42) 35(32-42) (mg/dl) HDL-C p<0/00 7(09-29) 29(7-42) (mmhg) p< 0/00 78(7-85) 8(72-90) (mmhg) p< 0/00 92(85-00) 96( 88-23) (mg/dl) 2

5 ( 5 ) Downloaded from ijdld.tums.ac.ir at 6:29 IRDT on Friday March 22nd 209 p<0/00 p<0/00 p<0/00 p<0/00 p<0/00 p<0/00 p<0/9 p<0/00 p< 0/00 p< 0/00 (6-74) ( 36-53) 56(52-60) 28(25-3) 25(87-246) 49(0-22) 37(4-63) 42(39-53) 7(07-30) 79(72-85) 9(85-99) (50-64) 53( 49-57) 29( 27-33) 245( ) 98( ) 60( 35-9) 42( 39-52) 40 ( 2-53) 83(77-93) 06(9-66) ( ) ( ) () (Kg/m 2 ) (mg/dl) (mg/dl) (mg/dl) LDL-C (mg/dl) HDL-C (mmhg) (mmhg) (mg/dl) -3 (57-60) 3 30 /84 (0/97-3/49) 0/063 /7 (0/8-3/62) 0/59 (53-56) /7 (/48-4/99) 0/00 /92 (0/92-4/0) 0/08 (3-52) 73 4/00 (2/24-7/4) <0/00 2/7 (/05-4/49) 0/037 ( ) ( ) OR (%95 CI) OR (%95 CI) 2 p-value p-value HDL- C LDL-C (74-95) (70-73) 3 5 /6 (0/77-/76) 0/480 /6 (0/73-/84) 0/539 (66-69) 2 54 /35 (0/90-2/04) 0/49 / (0/69-/77) 0/674 (42-65) 87 /72 (/8-2/49) 0/005 /03 (0/64-/65) 0/903 ( ) ( ) OR (%95 CI) OR (%95 p-value CI) 2 p-value HDL- C LDL-C

6 565 : : Downloaded from ijdld.tums.ac.ir at 6:29 IRDT on Friday March 22nd 209 /7.[26].[27] / /97 0/85 ( 6). %95..[28]..[29]..[22] (FEV).[30] /84 ( 4/3).[2] 0/85 McCarron. 4/ / [23] Goldbourt Tanne.[22] /3. / [24] [25]

7 ( 5 ) Downloaded from ijdld.tums.ac.ir at 6:29 IRDT on Friday March 22nd ) (29.. Buchan DS, Ollis S, Thomas NE, Baker JS. The influence of a high intensity physical activity intervention on a selection of health related outcomes: an ecological approach. BMC Public Health 200; 0: Sarraf-Zadegan N, Boshtam M, Malekafzali H, Bashardoost N, Sayed-Tabatabaei FA, Rafiei M, etal. Secular trends in cardiovascular mortality in Iran with special reference to Isfahan. Acta cardiol 999; 54: World health organization, Eastern Mediterranean Regional office (995) prevention and control of cardiovascular disease. Alexanderia: WHO- EMRO: Welborn TA, Dhaliwal SS: Preferred clinical measures of central obesity for predicting mortality. Eur J Clin Nutr 2007; 6(2): Calle EE, Thun MJ, Petrelli JM, Rodriguez C, Heath CW, Jr.: Body-mass index and mortality in a prospective cohort of U.S. adults. N Engl J Med 999; 34(5): Bogers RP, Bemelmans WJ, Hoogenveen RT, Boshuizen HC, Woodward M, Knekt P, van Dam RM, Hu FB, Visscher TL, Menotti A, et al. Association of overweight with increased risk of coronary heart disease partly independent of blood pressure and cholesterol levels: a metaanalysis of 2 cohort studies including more than (0/64-0/9) 0/92 (0/97- /80).[3] 0/ /42.[32] persons. Arch Intern Med 2007; 67(6): Katsuyuki Miura, Hideaki Nakagawa, and Philip Greenland. Invited Commentary: Height- Cardiovascular Disease Relation: Where to Go from Here? American Journal of Epidemiology 2002; 55(8): Lee GMY, Barzi F, Woodward M, Batty GD, Giles GG, Wong JW, Jamrozik K, Lam TH, Ueshima H, Kim HC, Gu DF, et al. Adult height and the risks of cardiovascular disease and major causes of death in the Asia-Pacific region: deaths in men and women. International Journal of Epidemiology 2009; 38: Zhang CX, Tse LA, Deng XQ, Jiang ZQ. Cardiovascular risk factors in overweight and obese Chinese children: a comparison of weightfor-height index and BMI as the screening criterion. Eur J Nutr 2008; 47(5): Kaori Honjo, Adult height and the risk of cardiovascular disease among middle aged men and omen in Japan, Eur J Epidemiol 20; 26: Wannamethee SG, Shaper AG, Whincup PH, Walker M. Adult Height, Stroke, and Coronary Heart Disease. American Journal of Epidemiology 998; 48(): Song YM, Smith GD, Sung J. Adult height and cause-specific mortality: a large prospective

8 567 : : Downloaded from ijdld.tums.ac.ir at 6:29 IRDT on Friday March 22nd 209 study of South Korean men. Am J Epidemiol 2003; 58(5): Song YM, Sung J. Adult height and the risk of mortality in South Korean women. Am J Epidemiol 2008; 68(5): Rich-Edwards JW, Manson JE, Stampfer MJ, Colditz GA, Willett WC, Rosner B,et al. Hennekens. Height and the Risk of Cardiovascular Disease in Women. American Journal of Epidemiology 995; 42(9): Jousilahti P. Relation of Adult Height to Causespecific and Total Mortality: A Prospective Follow-up Study of 3,99 Middle-aged Men and Women in Finland. American Journal of Epidemiology 2000; 5(): Azizi F, Rahmani M, Emami H, Mirmiran P, Hajipour R, Madjid M, et al. Cardiovascular risk factors in an Iranian urban population: Tehran lipid and glucose study. J Soz Prev Med 2002; 47: Azizi F, Esmailzadeh A, Mirmiran P. Obesity and cardiovascular risk factor in Tehran adults: population- Basel study. East Mediterr health J 2004; 20: Azizi F, Rahmani M, Ghanbarian A, Emami H, Salehi P, Mirmiran P, et al. Serum lipid levels in Iranian adult s population: Tehran lipid and glucose study. Eur J Epidemiol 2003; 78: Azizi F, Ghanbarian A, Majid M, Rahmani M. Distribution of blood pressure and prevalence of hypertension in Tehran adult population: Tehran Lipid and Clucose study (TLGS) J Hum Hypertens 2002; 6: Friedewald WT, levy RT, Fredrickson DS. Estimation of the concentration of Low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 972; 8: Lawlor DA, Taylor M, Davey Smith G, Gunnell D, Ebrahim S. Associations of components of adult height with coronary heart disease in postmenopausal women: the British women's heart and health study. Heart 2004; 90(7): McCarron P, Okasha M, McEwen J, Smith GD. Height in young adulthood and risk of death from cardio respiratory disease: a prospective study of male former students of Glasgow University, Scotland. Am J Epidemiol 2002; 55(8): Goldbourt U, Tanne D. Body height is associated with decreased long-term stroke but not coronary heart disease mortality?. Stroke 2002; 33(3): Yang L, Kuper H, Weiderpass E. Anthropometric characteristics as predictors of coronary heart disease in women. J Intern Med 2008; 264(): Song YM, Smith GD, Sung J. Adult height and cause- specific mortality: a large prospective study of South Korean men. Am J Epidemiol 2003; 58: Holmes VA, Cardwell C, McKinley MC, Young IS, Murray LJ, Boreham CA, et al. Association between breast-feeding and anthropometry and CVD risk factor status in adolescence and young adulthood: the Young Hearts Project, Northern Ireland. Public Health Nutr 200; 3(6): Silventoinen K, Kaprio J, Koskenvuo M, Lahelma E. The association between body height and coronary heart disease among finish twins and singletons. Int J Epidemiol 2003; 32: Lee CM, Barzi F, Woodward M, Batty GD, Giles GG, Wong JW, et al. Adult height and the risks of cardiovascular disease and major causes of death in the Asia-Pacific region: 2,000 deaths in 50,000 men and women. Int J Epidemiol 2009; 38(4): Batty GD, Shipley MJ, Gunnell D, Huxley R, Kivimaki M, Woodward M, Lee CM, Smith GD. Height, wealth, and health: an overview with new data from three longitudinal studies. Econ Hum Biol 2009; 7(2): Gunnell D, Whitley E, Upton MN, McConnachie A, Smith GD, Watt GC. Associations of height, leg length, and lung function with cardiovascular risk factors in the Midspan Family Study. J Epidemiol Community Health 2003; 57(2): Hozawa A, Murakami Y, Okamura T, Kadowaki T, Nakamura K, Hayakawa T, Kita Y, Nakamura Y, Okayama A, Ueshima H. Relation of adult height with stroke mortality in Japan. Stroke 2007; 38(): Wannamethee SG, Shaper AG, Lennon L, Whincup PH. Height loss in older men: associations with total mortality and incidence ofcardiovascular disease. Arch Intern Med 2006; 66(22):

Age-adjusted stroke mortality rate in Japan was the

Age-adjusted stroke mortality rate in Japan was the Relation of Adult Height With Stroke Mortality in Japan NIPPON DATA80 Atsushi Hozawa, MD; Yoshitaka Murakami, PhD; Tomonori Okamura, MD; Takashi Kadowaki, MD; Koshi Nakamura, MD; Takehito Hayakawa, PhD;