Experience of Korea Acute Myocardial Infarction Registry (KAMIR)
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1 Japan-Korea Joint AMI Symposium Korean Society of Myocardial Infarction Apr Experience of Korea Acute Myocardial Infarction Registry (KAMIR) Myung Ho Jeong, MD, PhD, FACC, FAHA, FESC, FSCAI, FAPSIC On Behalf of KAMIR Investigators Principal Investigator of Korea Acute Myocardial Infarction Registry, Director of Korea Cardiovascular Stent Research Institute, Director of Heart Research Center Nominated by Korea Ministry of Health and Welfare, Professor of Gwangju Institute of Science and Technology and Chonnam National University Hospital, Gwangju, Korea
2 61 th Japanese College of Cardiology, Sep , Kumamoto, Japan
3 Korea Acute Myocardial Infarction Registry (KAMIR) for the memorandum of 50 th Anniversary of Korean Circulation Society Sep th 2005
4 Kamir.or.kr On-line Korea Acute Myocardial Infarction Registry: KAMIR
5 KAMIR: Korea Acute Myocardial Infarction Registry Principal Investigator: Jeong MH Sub-investigators: Kim YJ, Kim CJ, Cho MC, Ahn YK Co-investigators: 55 primary PCI centers Ko YP, Koo BG, Gwon HC, Kim KS, Kim DI, Kim MH, Kim BO, Kim SW, Kim SJ, Kim YJ, Kim JK, Kim CJ, Kim TI, Rha SW, Rhew JY, Park GS, Park SW, Park SH, Bae JH, Seong IW, Seung KB, Ahn YK, Ahn TH, Yang JY, Oh SK, Yoon Jh, Lee HS, Lee MY, Lee SH, Lee SW, Rhim JY, Jeong KT, Jeong MH, Chung WS, Jeong HJ, Cho MC, Cho JH, Cho JM, Joo SJ, Jin DG, Jin SW, Chae SC, Chae IH, Chae JK, Choi DH, Tahk SJ, Han KR, Hur SH, Hwang JY Steering Committee: Park SJ, Jang YS, Seung KB, Chung WS, Cho JG, Kim YJ, Kim CJ, Cho MC, Yoon JH, Chae IH, Jeong MH
6 Purpose of KAMIR Study 1. On-line registration of Korean AMI patients 2. Early detection of high risk patients 3. Risk factor documentation and analysis 4. New therapeutic strategy for AMI 5. Effective prevention strategy for AMI
7 Four Phases of KAMIR Study KAMIR-I (Nov 2005-Dec 2006) N=8,489 KAMIR-II (Jan 2007-Jan 2008) N=6,381 (14,870) KAMIR-III (KorMI-I) (Feb 2008-Mar 2012) N=24,600 (39,470) KAMIR-IV (KorMI-II ) (Apr 2012~) KAMIR-NIH (Nov 2011~) N=12,616 (52,086)
8 KAMIR Publications and Presentations (2006~2014) Published Papers Presentations SCI Domestic Internatial Domestic Special Invited Lectures at 2012 Japanese Circulation Society and 2013 Japanese College of Cardiology and 2012 American College of Cardiology
9 Review Article in Journal of Cardiology 2010 KAMIR Investigators. J Cardiol 2010;56:1-7
10 Review Article in Journal of Korean Medical Science 2013 KAMIR Investigators. J Korean Med Sci 2013; 28:
11 Acute Myocardial Infarction in Korea Between Nov 2005 and Mar primary PCI centers 39,470 patients were enrolled in KAMIR/KorMI Mean age = 63±12 years of age
12 Age distribution in Korea AMI Pts % s 30s 40s 50s 60s 70s 80s 90s KAMIR Investigators
13 Distribution of Baseline Characteristics 29.5% 42.7% 70.5% 57.3% Male Female STEMI NSTEMI KAMIR Investigators
14 Gender Ratio in Age Group 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% Male Female s 30s 40s 50s 60s 70s 80s 90s Total KAMIR Investigators
15 STEMI vs. NSTEMI Ratio Change 70% STEMI NSTEMI 60% 63.3% 63.6% 50% 40% 58.5% 55.8% 56.1% % 46.2% % 43.9% 41.5% 30% 36.7% 36.4% 20% 10% 0%
16 Risk Factors % DL DL including TG and HDL-C Past Smoker Current Smoker HT DM HC Smoking FH
17 KAMIR Investigators. Int J Cardiol 2010;145:450-4
18 KAMIR Investigators. Int J Cardiol 2010;145:450-4
19 KAMIR Investigators. Int J Cardiol 2010;145:450-4
20 KAMIR Investigators. Int J Cardiol 2010;145:450-4
21 KAMIR Investigators. Am J Cardiol 2011;107:965-71
22 KAMIR Investigators. Am J Cardiol 2011;107:965-71
23 KAMIR Investigators. Am J Cardiol 2011;107:965-71
24 KAMIR Score GRACE Score KAMIR Investigators. Am J Cardiol 2011;107:965-71
25 KAMIR Investigators. Circulation 2009;119:
26 Triple vs. Dual antiplatelet therapy in AMI Pts KAMIR Investigators. Circulation 2009;119:
27 CNUH Data. J Cardiol 2014;63:99-106
28 KAMIR Investigators. J Am Coll Cardiol 2011;58:
29 Cumulative incidence of MACEs Statin therapy in AMI patients with LDL-C levels < 70 mg/dl Non-statin therapy group Statin therapy group p= Months after PCI No.at risk 1, Statin therapy group Non-statin therapy group KAMIR Investigators. J Am Coll Cardiol 2011;58:
30 KAMIR Investigators. Int J Cardiol 2014;170:291-7
31 KAMIR Investigators. Int J Cardiol 2014;170:291-7
32 Losartan, eprosartan Valsartan, candersatan. Irbesartan, telmisartan, olmesartan KAMIR Investigators. Int J Cardiol 2014;170:291-7
33 Revascularization in Multi-vessel Disease KAMIR Investigators, Int J Cardiol 2011;153:148-53
34 Revascularization in Multi-vessel Disease KAMIR Investigators, Int J Cardiol 2011;153:148-53
35 DES in Korean AMI Pts KAMIR Investigators. Int J Cardiol 2013; 163:1-4
36 DES in Korean AMI Pts KAMIR Investigators. Int J Cardiol 2013; 163:1-4
37 DES in Korean AMI Pts KAMIR Investigators. Int J Cardiol 2013; 163:1-4
38 KAMIR Investigators, Am J Cardiol 2011;108:8-14
39 KAMIR Investigators, Am J Cardiol 2011;108:8-14
40 KAMIR Investigators. J Cardiol 2012; 59:
41 KAMIR Investigators. J Cardiol 2012; 59:
42 KAMIR Investigators. J Cardiol 2012; 59:
43 KAMIR Investigators. Circ J 2013;77:
44 KAMIR Investigators. J Cardiol 2013;62:210-6
45 KAMIR Investigators. J Cardiol 2013;62:210-6
46 KAMIR Investigators. J Cardiol 2013;62:210-6
47 KAMIR Investigators. Int J Cardiol 2014;172:462-4
48 KAMIR Investigators. Int J Cardiol 2014;172:462-4
49 Summary of KAMIR Study 1. Pattern of dyslipidemia is different from western patients 2. Smoking rate should be decreased 3. KAMIR score is better than GRACE and TIMI score in the prediction of MACE 3. Triple anti-platelet therapy or prasugrel is better than ASA+clopidogrel in Korean AMI patients (esp. 5 mg prasugrel) 5. Statin therapy is beneficial in low LDL-C
50 Summary of KAMIR Study 6. ARB, esp. insurmountable, is better than ACEI 7. Multi-vessel PCI can be recommended in NSTEMI patients 8. DES is safer and more effective than BMS 9. Octogenarian can be treated by elective PCI using DES 10. Thrombus aspiration/ivus-guided PCI can be recommended in selective AMI patients
51 Korea Acute Myocardial Infarction Research Group Nov 19 th 2007
52 Korea National Institute of Health
53 1 st Meeting of Korea Society of Myocardial Infarction Feb 28 th 2014
54 I Hope Japan and Korea AMI Registry Will Be Successful in the Future!
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