Peritoneal Solute Transport Rate as an Independent Risk Factor for Total and Cardiovascular Mortality in a Population of Peritoneal Dialysis Patients
|
|
- Norman Henry
- 5 years ago
- Views:
Transcription
1 Advances in Peritoneal Dialysis, Vol. 30, 2014 Katarzyna Janda, 1 Marcin Krzanowski, 1 Paulina Dumnicka, 2 Beata Kuśnierz Cabala, 3 Przemysław Miarka, 1 Władysław Sułowicz 1 Peritoneal Solute Transport Rate as an Independent Risk Factor for Total and Cardiovascular Mortality in a Population of Peritoneal Dialysis Patients The aim of the present study was to assess the influence of peritoneal permeability expressed as the dialysate-to-plasma ratio of creatinine (D/P Cr) on total and cardiovascular (CV) mortality in a population of peritoneal dialysis (PD) patients during a 6-year observation period. The study recruited 55 patients (mean age: 53 years) treated with PD for a median of 24 months. Hematology parameters and serum albumin were determined using routine methods. Tumor necrosis factor α (TNF-α) and transforming growth factor β1 (TGF-β1) were determined by high-sensitivity ELISA. Peritoneal transport characteristics were identified using D/P Cr reference values after a peritoneal equilibration test. During the 6-year observation period, 22 patients (40%) died, mostly from CV complications (77% of deaths). In multiple Cox regression, D/P Cr and dialysate volume at PD initiation predicted total [hazard ratio (HR): 1.57; p = 0.02; and HR: 1.20; p = 0.04 respectively] and CV mortality (HR: 1.65; p = 0.02; and HR: 1.23; p = 0.05 respectively) independent of age, dialysis therapy duration, serum albumin concentration, dialysis adequacy measures, TGF-β1, and TNF-α. Additionally, TNF-α was independently associated with all-cause and CV mortality, and albumin, with all-cause mortality. Baseline D/P Cr was a strong independent marker of survival in PD patients. Baseline D/P Cr and From: 1 Chair and Department of Nephrology, 2 Department of Medical Diagnostics, and 3 Chair of Clinical Biochemistry, Jagiellonian University, Collegium Medicum, Cracow, Poland. dialysate volume were independent risk factors for total and CV mortality in the PD population and could be significant for assessing CV risk in this population. Key words Cardiovascular mortality, peritoneal solute transport rate, total mortality Introduction Cardiovascular (CV) diseases are the most frequent cause of comorbidity and mortality in patients with end-stage renal disease. Traditional risk factors for CV disease such as advanced age, diabetes mellitus, fluid volume overload, hypertension, and hyperlipidemia frequently coexist in patients with chronic kidney disease. The various dialysis modalities, such as continuous ambulatory peritoneal dialysis (CAPD), automated peritoneal dialysis (APD), and hemodialysis have different effects on fluid volume control. Automated peritoneal dialysis (PD) shares some characteristics with CAPD, and with the shorter dwell times used in APD, higher ultrafiltration volumes can be obtained (1). Peritoneal transport characteristics play an important role in determining morbidity, mortality, and management in PD patients. Small-solute peritoneal transport is assessed by the peritoneal equilibration test (2). Peritoneal transport varies from one patient to another and can change over time in the same patient. Patients with high small-solute peritoneal transport have an increased risk of morbidity and mortality despite their more rapid diffusive clearance of urea and creatinine. In patients with high peritoneal small-solute transport, the increased risk of mortality can potentially be mitigated by combining
2 16 PSTR as a Predictor for Mortality in PD Patients optimization of the short dwell times of APD with icodextrin use, rather than by using CAPD (3). Increases in the peritoneal solute transport rate (PSTR) are associated with an increased risk of mortality and a tendency to increased technique failure (4 7). Development of a high PSTR has been attributed to numerous factors, including hypoalbuminemia, comorbid disease, duration of PD (with exposure to high glucose), number and severity of peritonitis episodes, loss of residual renal function (RRF), and bioincompatible dialysis fluid (8 10). The aim of the present study was to assess the influence of peritoneal permeability expressed as the dialysate-to-plasma ratio of creatinine (D/P Cr) on total and CV mortality in a population of PD patients during a 6-year observation period. Methods The study group consisted of 55 patients (25 women, 30 men; mean age: 53 ± 13 years) being treated with PD (27 on APD, 28 on CAPD). Median duration of dialysis treatment was 24 months (range: months). On the day of blood collection, serum albumin was measured using an automated clinical chemistry analyzer (Modular P: Roche Diagnostics, Mannheim, Germany), and hematology parameters were assessed using an automated hematology analyzer (Sysmex XE 2100: Sysmex Corporation, Kobe, Japan). Sera samples for other laboratory tests were aliquoted and stored at more than 70 C. Measurements of tumor necrosis factor α (TNF-α) and transforming growth factor β1 (TGF-β1) were performed using highsensitivity ELISA kits (R&D Systems, Minneapolis, MN, U.S.A.). References ranges for the tests (Table I) represent the values set by the manufacturers. Peritoneal transport characteristics were identified using D/P Cr reference values after a peritoneal equilibration test (2,11). In addition, the PD dose was assessed using weekly Kt/V, weekly creatinine clearance (CCr), RRF, and dialysate volume. Body mass index was calculated using the Quetelet index. Data on mortality were collected over a 6-year (72-month) period. All deaths occurred in hospital, and the causes of death were determined according to disease history. The study was approved by the Bioethics Committee of Jagiellonian University, and all patients provided informed consent for their participation. Statistical analysis Number and proportion of patients in a group are reported for categorical variables, and mean ± standard deviation or median with lower and upper quartiles are reported for continuous variables, according to distribution. The Shapiro Wilks test was used to assess normality. Spearman coefficients were used to assess simple correlations (at least 1 variable being non-normally distributed). Survival curves were computed by the Kaplan Meier method. Unadjusted and adjusted hazard ratios (HRs) for all-cause and cardiovascular mortality were estimated by Cox proportional regression and are reported with 95% confidence intervals (CIs). All tests were two-sided, and results at p 0.05 were considered significant. The Statistica 9.0 statistical software application (StatSoft, Tulsa, OK, U.S.A.) was used for all computations. Results Table I presents clinical and biochemical characteristics and dialysis adequacy parameters for the study group. During the 6-year observation period, 22 patients died (17 from CV causes, 3 from encapsulating peritoneal sclerosis, and 2 from infections), 19 patients (35%) were transferred to hemodialysis, and 11 (20%) underwent renal transplantation. Median overall survival was 37 months. In univariate analysis, the D/P Cr was significantly positively associated with all-cause mortality (HR per 0.1 increase: 1.49; 95% CI: 1.08 to 2.04; p = 0.01) and approached statistical significance for mortality from CV causes (HR per 0.1 increase: 1.43; 95% CI: 0.99 to 2.04; p = 0.054). Figure 1 presents cumulative survival for patients having high-average and high (HA/H) peritoneal permeability (D/P Cr 0.65) compared with those having low-average and low (LA/L) peritoneal permeability (D/P Cr < 0.65). Significant correlations with mortality were also shown for dialysate volume (HR for all-cause mortality: 1.21; 95% CI: 1.04 to 1.41; p = 0.02; HR for CV mortality: 1.21; 95% CI: 1.02 to 1.45; p = 0.03). Another significant predictor of all-cause and CV mortality was TNF-α (HR: 1.57; 95% CI: 1.14 to 2.18; p = 0.006; HR: 1.70; 95% CI: 1.19 to 2.44; p = respectively). Albumin was associated with overall survival (HR: 0.89; 95% CI: 0.81 to 0.99; p = 0.03). Using multivariable analysis, we studied associations with survival in the context of dialysis adequacy
3 Janda et al. 17 table i Characteristics of the study group Characteristic Value [n (%)] Mean or median IQR Min Max Reference Patients 55 Age (years) 53± Sex Men 30 (55) Women 25 (45) Dialysis duration (months) Hypertension 47 (85) Ischemic heart disease 21 (38) Observation period (months) All-cause mortality 22 (40) Cardiovascular mortality 17 (31) Body mass index (kg/m 2 ) 25.3± Hemoglobin (g/dl) 11.9± Women: Men: White blood cells ( 10 3 /μl) 7.48± Albumin (g/l) 37.9± TNF-α (pg/ml) TGF-β1 (ng/ml) Weekly Kt/V >1.7 Weekly CCr (L/1.73 m 2 ) >45 RRF (ml/min/1.73 m 2 ) D/P creatinine 0.63± Dialysate volume (dl/24 h) IQR = interquartile range; Min = minimum; Max = maximum; TNF-α = tumor necrosis factor α; TGF-β1 = transforming growth factor β1; CCr = creatinine clearance; RRF = residual renal function. (weekly Kt/V and CCr), RRF, TGF-β1, age, and dialysis duration. However, the correlation of D/P Cr with dialysate volume was so highly significant (R = 0.45, p = ) that, to avoid redundancy, we constructed separate multiple Cox regression models including either D/P Cr or dialysate volume. In multivariable Cox regression, D/P Cr was an independent predictor of total and CV mortality (Table II). Similarly, dialysate volume was shown to predict mortality independently of the other studied variables (Table III). Additionally, proinflammatory TNF-α was independently associated with total and CV mortality (Tables II and III). figure 1 Kaplan Meier survival curves for all-cause mortality in patients with a dialysate-to-plasma creatinine ratio of 0.65 or more (solid line) and less than 0.65 (dashed line), log-rank p = Discussion In PD, the PSTR is a major determinant of patient survival. Our study shows that in the population of PD patients, D/P Cr and dialysate volume both
4 18 PSTR as a Predictor for Mortality in PD Patients table ii Cox regression models including dialysate-to-plasma (D/P) creatinine Independent variable All-cause mortality Cardiovascular mortality HR 95% CI p Value HR 95% CI p Value D/P creatinine Change of to to Albumin Grams per liter to to TNF-α Picograms per milliliter to to TGF-β1 Nanograms per milliliter to to Weekly Kt/V to to Weekly CCr Liters per 1.73 m to to RRF Milliliters per minute per 1.73 m to to Dialysis duration Months to to Age Years to to HR = hazard ratio; CI = confidence interval; TNF-α = tumor necrosis factor α; TGF-β1 = transforming growth factor β1; CCr = creatinine clearance; RRF = residual renal function. table iii Cox regression models including dialysate volume Independent variable All-cause mortality Cardiovascular mortality HR 95% CI p Value HR 95% CI p Value Dialysate volume Deciliters in 24 hours to to Albumin Grams per liter to to TNF-α Picograms per milliliter to to TGF-β1 Nanograms per milliliter to to Weekly Kt/V to to Weekly CCr Liters per 1.73 m to to RRF Milliliters per minute per 1.73 m to to Dialysis duration Months to to Age Years to to HR = hazard ratio; CI = confidence interval; TNF-α = tumor necrosis factor α; TGF-β1 = transforming growth factor β1; CCr = creatinine clearance; RRF = residual renal function. predicted CV and all-cause mortality independently of inflammatory cytokines, albumin level, dialysis adequacy (weekly Kt/V and CCr), RRF, age, and dialysis therapy duration. Authors from the Karolinska Institutet indicated that intraperitoneal and systemic inflammation increase in PD patients during the first year of therapy. Intraperitoneal and systemic inflammation might be interrelated, and the interleukin 6 (IL-6) system might be a link. Particularly in the early phase of PD treatment, IL-6 is associated with PSTR, and smalland large-solute transport are linked. Inflammation might be responsible for the development of a high PSTR, which could potentially be a reason for the high mortality in patients with a high PSTR (12). Higher solute transport at the start of PD might be associated with the risk of peritonitis. Gołembiewska et al. (13) showed that solute transport measured as D/P Cr during the peritoneal equilibration test was significantly higher in the group of patients who had experienced a peritonitis episode than in the group of peritonitis-free patients. Matsuo et al. (14) evaluated risk factors and mortality in PD patients. In their group of 98 patients, the leading causes of death were CV and infectious disease. Patients who died were significantly older and more frequently had a history of CV disease. Their serum albumin was significantly lower, and their D/P Cr was higher. The authors postulated that diabetic nephropathy, a history of CV disease,
5 Janda et al. 19 and higher peritoneal permeability at PD initiation are independent risk factors for death in patients starting PD. In another study, Rodrigues et al. (15) revealed that fast peritoneal transport at baseline was not associated with markers of systemic inflammation, nor was it predictive of worse patient survival in incident PD patients. In a population with preserved RRF and an absence of serious baseline comorbidity, it was not predictive of a worse prognosis. Fast transporters did not present higher levels of C-reactive protein (CRP) or serum IL-6. Patients with more than 2 comorbidities had lower levels of plasma albumin, significantly higher median levels of serum IL-6, and a greater intima media thickness. Multivariate analysis confirmed that baseline peritoneal transport was not a significant determinant of patient survival, but comorbidity score remained significant. In our multivariable Cox regression (adjusted for all studied variables and for age and dialysis therapy duration), D/P Cr at PD initiation was an independent predictor of total and CV mortality. In dialyzed patients (CAPD or hemodialysis), the concentrations of inflammatory factors, especially high-sensitivity CRP and TNF-α, are increased. In a study by Kir et al. (16), the highest increases in TNF-α were observed in patients on CAPD. In our multivariable analysis, an increased TNF-α concentration at baseline was independently associated with increased all-cause and CV mortality. Peritoneal transport status is one of the main determinants of dialysis adequacy and of dialysisrelated complications in chronic kidney disease patients who undergo PD (17). Zhe et al. (18) showed that carotid femoral pulse wave velocity, established as a CV risk factor, was positively associated with patient age, time on PD, diabetes status, D/P Cr, pulse pressure, and the ratio of extracellular water to total body water. In multivariate regression analysis, pulse wave velocity was independently determined by the ratio of extracellular water to total body water, pulse pressure, age, and D/P Cr, suggesting that greater aortic stiffness and an increased rate of peritoneal small-solute transport might be linked. In another study, Sezer et al. (19) investigated the relationship between peritoneal transport characteristics and known promoters of atherosclerosis in PD patients. After 36 months, those authors observed that, compared with LA/L transport, HA/H transport was associated with lower albumin, higher CRP, and a higher need for recombinant human erythropoietin. During follow-up, 28 of 84 patients showed an atherosclerosis-related event (myocardial infarction, coronary artery disease diagnosis by angiography or myocardial scintigraphy, cerebrovascular accident, or development of clinically evident peripheral arterial disease). Of those 28 patients, 22 were in the HA/H group (constituting 43.1% of that group), and only 6 were in the LA/L group (constituting 18.1% of the group, p < 0.01). Re-analysis of the 18 patients with atherosclerosis-related events and high CRP levels (>10 mg/l) showed that 15 were in the HA/H group, and 3 were in the LA/L group. Of patients with an atherosclerotic event, 68% belonging to the HA/H group and 50% belonging to the LA/L group also had chronic inflammation (p < 0.001). A Pearson correlation analysis showed that D/P Cr was positively correlated with 36-month mean CRP concentration and negatively correlated with 36-month mean serum albumin. A high-transport peritoneal membrane characteristic was thus shown to be a risk factor for an inflammatory state in patients with end-stage renal disease. Compared with their low-transport counterparts, high-transport patients were at an increased risk of atherosclerosis through chronic inflammation (19). Sawai et al. (20) investigated the relationships of local peritoneal inflammation, angiogenesis, and systemic inflammation with baseline permeability. Peritoneal biopsy specimens from 42 pre-dialysis uremic patients and 11 control subjects were investigated. Compared with control peritoneum, predialysis uremic peritoneum showed infiltration by CD68+ macrophages and mast cells. Baseline D/P Cr correlated with the density of CD68+ macrophages, IL-6 positive cells, CD31-positive blood vessels, and serum albumin. On multiple linear regression analysis, the number of CD68+ macrophages in peritoneum was an independent predictor of baseline peritoneal permeability. Our study shows that PSTR is an important determinant of survival in PD patients. Additionally, high PSTR at PD initiation is associated with an increased risk for total and CV mortality. Conclusions Baseline D/P Cr represents a strong independent marker of survival of PD patients. Baseline D/P Cr and dialysate volume are independent risk factors for
6 20 PSTR as a Predictor for Mortality in PD Patients total mortality and for CV mortality in the PD population and can be significant markers in the assessment of CV risk in that population. Acknowledgments This work was supported by a department grant (no. K/ZDS/000597) and was previously presented as a poster during the 49th ERA-EDTA Congress; Paris, France; May 24 27, Disclosures The authors have no financial conflicts of interest to declare. References 1 Paniagua R, Ventura MD, Avila Díaz M, et al. NTproBNP, fluid volume overload and dialysis modality are independent predictors of mortality in ESRD patients. Nephrol Dial Transplant 2010;25: Twardowski ZJ. Clinical value of standardized equilibration tests in CAPD patients. Blood Purif 1989;7: La Milia V, Limardo M, Cavalli A, Crepaldi M, Locatelli F. Transport of peritoneal membrane assessed before and after the start of peritoneal dialysis. Nephrol Dial Transplant 2009;24: Churchill DN, Thorpe KE, Nolph KD, Keshaviah PR, Oreopoulos DG, Pagé D. Increased peritoneal membrane transport is associated with decreased patient and technique survival for continuous peritoneal dialysis patients. The Canada USA (CANUSA) Peritoneal Dialysis Study Group. J Am Soc Nephrol 1998;9: Brimble KS, Walker M, Margetts PJ, Kundhal KK, Rabbat CG. Meta-analysis: peritoneal membrane transport, mortality, and technique failure in peritoneal dialysis. J Am Soc Nephrol 2006;17: Rumpsfeld M, McDonald SP, Johnson DW. Higher peritoneal transport status is associated with higher mortality and technique failure in the Australian and New Zealand peritoneal dialysis patient populations. J Am Soc Nephrol 2006;17: Cueto Manzano AM. Rapid solute transport in the peritoneum: physiologic and clinical consequences. Perit Dial Int 2009;29(suppl 2):S Margetts PJ, McMullin JP, Rabbat CG, Churchill DN. Peritoneal membrane transport and hypoalbuminemia: cause or effect? Perit Dial Int 2000;20: Davies SJ, Phillips L, Naish PF, Russell GI. Quantifying comorbidity in peritoneal dialysis patients and its relationship to other predictors of survival. Nephrol Dial Transplant 2002;17: Oh KH, Moon JY, Oh J, et al. Baseline peritoneal solute transport rate is not associated with markers of systemic inflammation or comorbidity in incident Korean peritoneal dialysis patients. Nephrol Dial Transplant 2008;23: Krediet RT, Struijk DG. Peritoneal dialysis membrane evaluation in clinical practice. Contrib Nephrol 2012;178: Pecoits Filho R, Carvalho MJ, Stenvinkel P, Lindholm B, Heimbürger O. Systemic and intraperitoneal interleukin-6 system during the first year of peritoneal dialysis. Perit Dial Int 2006;26: Gołembiewska E, Safranow K, Kabat Koperska J, Ciechanowski K, Romanowski M. Solute transport at the start of peritoneal dialysis and the risk of peritonitis. Adv Clin Exp Med 2013;22: Matsuo N, Maruyama Y, Terawaki H, et al. Risk factors for death in patients starting PD for their first renal replacement therapy [Japanese]. Nihon Jinzo Gakkai Shi 2009;51: Rodrigues AS, Almeida M, Fonseca I, et al. Peritoneal fast transport in incident peritoneal dialysis patients is not consistently associated with systemic inflammation. Nephrol Dial Transplant 2006;21: Kir HM, Eraldemir C, Dervisoglu E, Caglayan C, Kalender B. Effects of chronic kidney disease and type of dialysis on serum levels of adiponectin, TNFalpha and high sensitive C-reactive protein. Clin Lab 2012;58: Kim YL. Update on mechanisms of ultrafiltration failure. Perit Dial Int 2009;29(suppl 2): Zhe XW, Tian XK, Chen W, et al. Association between arterial stiffness and peritoneal small solute transport rate. Artif Organs 2008;32: Sezer S, Tutal E, Arat Z, et al. Peritoneal transport status influence on atherosclerosis/inflammation in CAPD patients. J Ren Nutr 2005;15: Sawai A, Ito Y, Mizuno M, et al. Peritoneal macrophage infiltration is correlated with baseline peritoneal solute transport rate in peritoneal dialysis patients. Nephrol Dial Transplant 2011;26: Corresponding author: Katarzyna Janda, md phd, Department of Nephrology, Jagiellonian University, Collegium Medicum, Kopernika 15C Street, Cracow Poland. kasiajanda@op.pl
PART ONE. Peritoneal Kinetics and Anatomy
PART ONE Peritoneal Kinetics and Anatomy Advances in Peritoneal Dialysis, Vol. 22, 2006 Paul A. Fein, Irfan Fazil, Muhammad A. Rafiq, Teresa Schloth, Betty Matza, Jyotiprakas Chattopadhyay, Morrell M.
More informationEarly Estimation of High Peritoneal Permeability Can Predict Poor Prognosis for Technique Survival in Patients on Peritoneal Dialysis
Advances in Peritoneal Dialysis, Vol. 22, 2006 Hidetomo Nakamoto, 1,2 Hirokazu Imai, 2 Hideki Kawanishi, 2 Masahiko Nakamoto, 2 Jun Minakuchi, 2 Shinichi Kumon, 2 Syuichi Watanabe, 2 Yoshhiko Shiohira,
More information3/21/2017. Solute Clearance and Adequacy Targets in Peritoneal Dialysis. Peritoneal Membrane. Peritoneal Membrane
3/21/2017 Solute Clearance and Adequacy Targets in Peritoneal Dialysis Steven Guest MD Director, Medical Consulting Services Baxter Healthcare Corporation Deerfield, IL, USA Peritoneal Membrane Image courtesy
More informationThe CARI Guidelines Caring for Australians with Renal Impairment. Peritoneal transport and ultrafiltration GUIDELINES
Date written: January 2004 Final submission: May 2004 Peritoneal transport and ultrafiltration GUIDELINES No recommendations possible based on Level I or II evidence SUGGESTIONS FOR CLINICAL CARE (Suggestions
More informationThe CARI Guidelines Caring for Australians with Renal Impairment. Monitoring patients on peritoneal dialysis GUIDELINES
Date written: August 2004 Final submission: July 2005 Monitoring patients on peritoneal dialysis GUIDELINES No recommendations possible based on Level I or II evidence SUGGESTIONS FOR CLINICAL CARE (Suggestions
More informationAdvances in Peritoneal Dialysis, Vol. 23, 2007
Advances in Peritoneal Dialysis, Vol. 23, 2007 Antonios H. Tzamaloukas, 1,2 Aideloje Onime, 1,2 Dominic S.C. Raj, 2 Glen H. Murata, 1 Dorothy J. VanderJagt, 3 Karen S. Servilla 1,2 Computation of the Dose
More informationEffect of Initial PET Status on Clinical Course in Peritoneal Dialysis Patients
BANTAO Journal 2015; 13(1): 14-19; doi:10.1515/bj-2015-0004 BJ BANTAO Journal Original article Effect of Initial PET Status on Clinical Course in Peritoneal Dialysis Patients Tamer Sakaci¹, Yener Koc²,
More informationMethods. Original Article. Abstract
Original Article Influence of Peritoneal Transport Characteristics on Nutritional Status and Clinical Outcome in Chinese Diabetic Nephropathy Patients on Peritoneal Dialysis Ji Chao Guan 1,2, Wei Bian
More informationPredictive Factors for Withdrawal from Peritoneal Dialysis: A Retrospective Cohort Study at Two Centers in Japan
Advances in Peritoneal Dialysis, Vol. 33, 2017 Yasuhiro Taki, 1 Tsutomu Sakurada, 2 Kenichiro Koitabashi, 2 Naohiko Imai, 1 Yugo Shibagaki 2 Predictive Factors for Withdrawal from Peritoneal Dialysis:
More informationEffect of previously failed kidney transplantation on peritoneal dialysis outcomes in the Australian and New Zealand patient populations
NDT Advance Access published November 9, 2005 Nephrol Dial Transplant (2005) 1 of 8 doi:10.1093/ndt/gfi248 Original Article Effect of previously failed kidney transplantation on peritoneal dialysis outcomes
More informationChapter 2 Peritoneal Equilibration Testing and Application
Chapter 2 Peritoneal Equilibration Testing and Application Francisco J. Cano Case Presentation FW, a recently diagnosed patient with CKD Stage 5, is a 6-year-old boy who has been recommended to initiate
More informationAdvances in Peritoneal Dialysis, Vol. 29, 2013
Advances in Peritoneal Dialysis, Vol. 29, 2013 Takeyuki Hiramatsu, 1 Takahiro Hayasaki, 1 Akinori Hobo, 1 Shinji Furuta, 1 Koki Kabu, 2 Yukio Tonozuka, 2 Yoshiyasu Iida 1 Icodextrin Eliminates Phosphate
More informationAna Paula Bernardo. CHP Hospital de Santo António ICBAS/ Universidade do Porto
Ana Paula Bernardo CHP Hospital de Santo António ICBAS/ Universidade do Porto Clinical relevance of hyperphosphatemia Phosphate handling in dialysis patients Phosphate kinetics in PD peritoneal phosphate
More informationPeritoneal Dialysis Adequacy: Not Just Small- Solute Clearance
Advances in Peritoneal Dialysis, Vol. 24, 2008 Rajesh Yalavarthy, Isaac Teitelbaum Peritoneal Dialysis Adequacy: Not Just Small- Solute Clearance Two indices of small-solute clearance, Kt/V urea and creatinine
More informationPredictors of Patient Survival in Continuous Ambulatory Peritoneal Dialysis 10-Year Experience in 2 Major Centers in Tehran
Dialysis Predictors of Patient Survival in Continuous Ambulatory Peritoneal Dialysis 10-Year Experience in 2 Major Centers in Tehran Monir Sadat Hakemi, 1 Mehdi Golbabaei, 2 Amirahmad Nassiri, 3 Mandana
More informationProceedings of the ISPD 2006 The 11th Congress of the ISPD /07 $ MAXIMIZING THE SUCCESS OF PERITONEAL DIALYSIS IN HIGH TRANSPORTERS
Proceedings of the ISPD 2006 The 11th Congress of the ISPD 0896-8608/07 $3.00 +.00 August 25 29, 2006, Hong Kong Copyright 2007 International Society for Peritoneal Dialysis Peritoneal Dialysis International,
More informationThe CARI Guidelines Caring for Australians with Renal Impairment. Mode of dialysis at initiation GUIDELINES
Date written: September 2004 Final submission: February 2005 Mode of dialysis at initiation GUIDELINES No recommendations possible based on Level I or II evidence SUGGESTIONS FOR CLINICAL CARE (Suggestions
More informationThe greatest benefit of peritoneal dialysis (PD) is the
Peritoneal Dialysis International, Vol. 26, pp. 150 154 Printed in Canada. All rights reserved. 0896-8608/06 $3.00 +.00 Copyright 2006 International Society for Peritoneal Dialysis COMBINATION THERAPY
More informationMalnutrition and inflammation in peritoneal dialysis patients
Kidney International, Vol. 64, Supplement 87 (2003), pp. S87 S91 Malnutrition and inflammation in peritoneal dialysis patients PAUL A. FEIN, NEAL MITTMAN, RAJDEEP GADH, JYOTIPRAKAS CHATTOPADHYAY, DANIEL
More informationHyaluronan Influence on Diffusive Permeability of the Peritoneum In Vitro
Advances in Peritoneal Dialysis, Vol. 24, 2008 Teresa Grzelak, Beata Szary, Krystyna Czyzewska Hyaluronan Influence on Diffusive Permeability of the Peritoneum In Vitro Hyaluronan (HA), an essential component
More informationYou can sleep while I dialyze
You can sleep while I dialyze Nocturnal Peritoneal Dialysis Dr. Suneet Singh Medical Director, PD, VGH Division of Nephrology University of British Columbia Acknowledgements Melissa Etheridge You can sleep
More informationThe Effect of Residual Renal Function at the Initiation of Dialysis on Patient Survival
ORIGINAL ARTICLE DOI: 10.3904/kjim.2009.24.1.55 The Effect of Residual Renal Function at the Initiation of Dialysis on Patient Survival Seoung Gu Kim 1 and Nam Ho Kim 2 Department of Internal Medicine,
More informationPeritoneal dialysis as a treatment option in autosomal dominant polycystic kidney disease
Int Urol Nephrol (2015) 47:1739 1744 DOI 10.1007/s11255-015-1087-9 NEPHROLOGY - ORIGINAL ARTICLE Peritoneal dialysis as a treatment option in autosomal dominant polycystic kidney disease Magdalena Jankowska
More informationPERITONEAL DIALYSIS PRESCRIPTION MANAGEMENT QUICK REFERENCE GUIDE
PERITONEAL DIALYSIS PRESCRIPTION MANAGEMENT QUICK REFERENCE GUIDE This quick reference guide will help serve as a reference tool for clinicians setting a patient s Peritoneal Dialysis (PD) prescription.
More informationDe Novo Hypokalemia in Incident Peritoneal Dialysis
Original investigation 73 1) De Novo Hypokalemia in Incident Peritoneal Dialysis Patients: A 1-Year Observational Study Ji Yong Jung, M.D., Jae Hyun Chang, M.D., Hyun Hee Lee, M.D., Wookyung Chung, M.D.
More informationHigh-sensitivity Troponin T Predicts Recurrent Cardiovascular Events in Patients with Stable Coronary Heart Disease: KAROLA Study 8 Year FU
ESC Congress 2011 Paris, France, August 27-31 KAROLA Session: Prevention: Are biomarkers worth their money? Abstract # 84698 High-sensitivity Troponin T Predicts Recurrent Cardiovascular Events in Patients
More informationIntravenous Iron Does Not Affect the Rate of Decline of Residual Renal Function in Patients on Peritoneal Dialysis
Advances in Peritoneal Dialysis, Vol. 22, 2006 Hemal Shah, Ashutosh Shukla, Abirami Krishnan, Theodore Pliakogiannis, Mufazzal Ahmad, Joanne M. Bargman, Dimitrios G. Oreopoulos Intravenous Iron Does Not
More informationWhat Does Peritoneal Thickness in Peritoneal Dialysis Patients Tell Us?
Advances in Peritoneal Dialysis, Vol. 23, 2007 Soner Duman, 1 Suha Sureyya Ozbek, 2 Ebru Sevinc Gunay, 1 Devrim Bozkurt, 1 Gulay Asci, 1 Savas Sipahi, 1 Fatih Kirçelli, 1 Muhittin Ertilav, 1 Mehmet Özkahya,
More informationDaily peritoneal ultrafiltration predicts patient and technique survival in anuric peritoneal dialysis patients
2322 X. Lin et al. gy data. Journal of the American Statistical Association 1993; 88: 400 409 32. Bodnar E, Blackstone EH. An actual problem: another issue of apples and oranges. J Thorac Cardiovasc Surg
More informationMaintaining Peritoneal Dialysis Adequacy: The Process of Incremental Prescription
Advances in Peritoneal Dialysis, Vol. 34, 2018 Susie Q. Lew Maintaining Peritoneal Dialysis Adequacy: The Process of Incremental Prescription Urea kinetics (weekly Kt/V) greater than 1.7 generally define
More informationThe CARI Guidelines Caring for Australians with Renal Impairment. Level of renal function at which to initiate dialysis GUIDELINES
Level of renal function at which to initiate dialysis Date written: September 2004 Final submission: February 2005 GUIDELINES No recommendations possible based on Level I or II evidence SUGGESTIONS FOR
More informationOriginal Article. Key words: Icodextrin, peritoneal dialysis, metabolic effects, ultrafiltration
Original Article 133 Clinical Experience of One-Year Icodextrin Treatment in Peritoneal Dialysis Patients Chun-Shuo Hsu *, Chien-Yu Su **, Chih-Hung Chang ***, Kao-Tai Hsu **, King-Kwan Lam **, Shang-Chih
More information2016 Annual Dialysis Conference Michelle Hofmann RN, BSN, CNN Renal Clinical Educator - Home
Fluid Management 2016 Annual Dialysis Conference Michelle Hofmann RN, BSN, CNN Renal Clinical Educator - Home Objectives Define euvolemia Determine factors which contribute to fluid imbalance Discuss strategies
More informationHTA ET DIALYSE DR ALAIN GUERIN
HTA ET DIALYSE DR ALAIN GUERIN Cardiovascular Disease Mortality General Population vs ESRD Dialysis Patients 100 Annual CVD Mortality (%) 10 1 0.1 0.01 0.001 25-34 35-44 45-54 55-64 66-74 75-84 >85 Age
More informationOverweight Rather Than Malnutrition Is Widely Prevalent in Peritoneal Dialysis Patients
Advances in Peritoneal Dialysis, Vol. 25, 2009 Ana P. Bernardo, 1 Isabel Fonseca, 2 Anabela Rodrigues, 2 Maria J. Carvalho, 2 António Cabrita 2 Overweight Rather Than Malnutrition Is Widely Prevalent in
More informationHaemodiafiltration - the case against. Prof Peter G Kerr Professor/Director of Nephrology Monash Health
Haemodiafiltration - the case against Prof Peter G Kerr Professor/Director of Nephrology Monash Health Know your opposition.. Haemodiafiltration NB: pre or post-dilution What is HDF how is it different
More informationObjectives. Peritoneal Dialysis vs. Hemodialysis 02/27/2018. Peritoneal Dialysis Prescription and Adequacy Monitoring
Peritoneal Dialysis Prescription and Adequacy Monitoring Christine B. Sethna, MD, EdM Division Director, Pediatric Nephrology Cohen Children s Medical Center Associate Professor Hofstra Northwell School
More informationPART FOUR. Metabolism and Nutrition
PART FOUR Metabolism and Nutrition Advances in Peritoneal Dialysis, Vol. 22, 2006 Costas Fourtounas, Eirini Savidaki, Marilena Roumelioti, Periklis Dousdampanis, Andreas Hardalias, Pantelitsa Kalliakmani,
More informationStrategies to Preserve the Peritoneal Membrane. Reusz GS Ist Dept of Pediatrics Semmelweis University, Budapest
Strategies to Preserve the Peritoneal Membrane Reusz GS Ist Dept of Pediatrics Semmelweis University, Budapest Outline 1. Structure of the peritoneal membrane 2. Mechanisms of peritoneal injury 3. Signs
More informationPhosphate Clearance in Peritoneal Dialysis: Automated PD Compared with Continuous Ambulatory PD
Advances in Peritoneal Dialysis, Vol. 28, 2012 Dixie-Ann Sawin, Rainer Himmele, Jose A. Diaz Buxo Phosphate Clearance in Peritoneal Dialysis: Automated PD Compared with Continuous Ambulatory PD Although
More informationBiologically active form of vitamin B1 in human peritoneal effluent
Original papers Biologically active form of vitamin B1 in human peritoneal effluent Magdalena Jankowska 1, A D, Monika Lichodziejewska-Niemierko 1, C, E, F, Sylwia Małgorzewicz 2, B, E, F 1, C, E, F, Bolesław
More informationContinuous Ambulatory Peritoneal Dialysis and Automated Peritoneal Dialysis: What, Who, Why, and How? Review and Case Study
Advances in Peritoneal Dialysis, Vol. 33, 2017 Kunal Malhotra, Ramesh Khanna Continuous Ambulatory Peritoneal Dialysis and Automated Peritoneal Dialysis: What, Who, Why, and How? Review and Case Study
More informationVincenzo La Milia 1, Giuseppe Pontoriero 1, Giovambattista Virga 2 and Francesco Locatelli 1
Nephrol Dial Transplant (2015) 30: 1741 1746 doi: 10.1093/ndt/gfv275 Advance Access publication 16 July 2015 Ionic conductivity of peritoneal dialysate: a new, easy and fast method of assessing peritoneal
More informationChapter 12 PERITONEAL DIALYSIS
Chapter 12 PERITONEAL DIALYSIS B. Sunita A/P V. Bavanandan Anita Bhajan Manocha Lily Binti Mushahar Mohamad Zaimi Bin Abdul Wahab Sudhaharan Sivathasan PERITONEAL DIALYSIS 22nd Report of the SECTION 12.1:
More informationTitle:Hyperphosphatemia as an Independent Risk Factor of Coronary Artery Calcification Progression in Peritoneal Dialysis Patients
Author's response to reviews Title:Hyperphosphatemia as an Independent Risk Factor of Coronary Artery Calcification Progression in Peritoneal Dialysis Patients Authors: Da Shang (sdshangda@163.com) Qionghong
More informationIntermittent peritoneal dialysis (IPD) has occasionally
Peritoneal Dialysis International, Vol. 32, pp. 142 148 doi: 10.3747/pdi.2011.00027 0896-8608/12 $3.00 +.00 Copyright 2012 International Society for Peritoneal Dialysis INTERMITTENT PERITONEAL DIALYSIS:
More informationSequential peritoneal equilibration test: a new method for assessment and modelling of peritoneal transport
Nephrol Dial Transplant (2013) 28: 447 454 doi: 10.1093/ndt/gfs592 Sequential peritoneal equilibration test: a new method for assessment and modelling of peritoneal transport Magda Galach 1, Stefan Antosiewicz
More informationHyperphosphatemia is a strong predictor of overall
Peritoneal Phosphate Clearance is Influenced by Peritoneal Dialysis Modality, Independent of Peritoneal Transport Characteristics Sunil V. Badve,* Deborah L. Zimmerman,* Greg A. Knoll, * Kevin D. Burns,*
More informationTHERAPEUTIC INTERVENTIONS TO PRESERVE RESIDUAL KIDNEY FUNCTION. Rajnish Mehrotra Harborview Medical Center University of Washington, Seattle
THERAPEUTIC INTERVENTIONS TO PRESERVE RESIDUAL KIDNEY FUNCTION Rajnish Mehrotra Harborview Medical Center University of Washington, Seattle 1 2 Outline of Presentation Refinements in our understanding
More informationNo increase in small-solute transport in peritoneal dialysis patients treated without hypertonic glucose for fifty-four months
Pagniez et al. BMC Nephrology (2017) 18:278 DOI 10.1186/s12882-017-0690-7 RESEARCH ARTICLE No increase in small-solute transport in peritoneal dialysis patients treated without hypertonic glucose for fifty-four
More informationMETHODS RESULTS. Patients
ORIGINAL ARTICLE Korean J Intern Med 2014;29:489-497 Ferritin as a predictor of decline in residual renal function in peritoneal dialysis patients Soon Mi Hur, Hye Young Ju, Moo Yong Park, Soo Jeong Choi,
More informationGeriatric Nutritional Risk Index, home hemodialysis outcomes 131
Subject Index Aksys PHD system 113 Anemia, home outcomes 111, 172, 173 Automated peritoneal dialysis dialysis comparison 17, 18 selection factors 18, 19 telemedicine system 19 21 Blood pressure -peritoneal
More informationPeritoneal dialysis adequacy: A model to assess feasibility with various modalities
Kidney International, Vol. 55 (1999), pp. 2493 2501 Peritoneal dialysis adequacy: A model to assess feasibility with various modalities JOSE A. DIAZ-BUXO, FRANK A. GOTCH, TOM I. FOLDEN, SHELDEN ROSENBLUM,
More informationFree water transport: Clinical implications. Sodium sieving during short very hypertonic dialysis exchanges
Free water transport: Clinical implications Raymond T Krediet, MD,PhD University of Amsterdam Sodium sieving during short very hypertonic dialysis exchanges Nolph KD et al. Ann Int Med 1969;70:931-947
More information02/21/2017. Assessment of the Peritoneal Membrane: Practice Workshop. Objectives. Review of Physiology. Marina Villano, MSN, RN, CNN
Assessment of the Peritoneal Membrane: Practice Workshop Marina Villano, MSN, RN, CNN marina.villano@fmc-na.com Objectives Briefly review normal peritoneal physiology including the three pore model. Compare
More informationUltrafiltration failure (UFF) is an important cause of
Peritoneal Dialysis International, Vol. 32, pp. 537 544 doi: 10.3747/pdi.2011.00175 0896-8608/12 $3.00 +.00 Copyright 2012 International Society for Peritoneal Dialysis TWO-IN-ONE PROTOCOL: SIMULTANEOUS
More informationFrom Peritoneal Dialysis to Hemodialysis How could we improve the transition? Th Lobbedez CHU de Caen Self Dialysis Meeting 22 May 2014
From Peritoneal Dialysis to Hemodialysis How could we improve the transition? Th Lobbedez CHU de Caen Self Dialysis Meeting 22 May 2014 Deux grands principes concernant la DP La dialyse péritonéale doit
More informationThe outcomes of continuous ambulatory and automated peritoneal dialysis are similar
http://www.kidney-international.org & 2009 International Society of Nephrology see commentary on page 12 The outcomes of continuous ambulatory and automated peritoneal dialysis are similar Rajnish Mehrotra
More informationEvaluation and management of nutrition in children
Evaluation and management of nutrition in children Date written: May 2004 Final submission: January 2005 Author: Elisabeth Hodson GUIDELINES No recommendations possible based on Level I or II evidence
More informationCentral pressures and prediction of cardiovascular events in erectile dysfunction patients
Central pressures and prediction of cardiovascular events in erectile dysfunction patients N. Ioakeimidis, K. Rokkas, A. Angelis, Z. Kratiras, M. Abdelrasoul, C. Georgakopoulos, D. Terentes-Printzios,
More informationM. Kalousová, H. Benáková, A. A. Kuběna, S. Dusilová-Sulková, V. Tesař, T. Zima
Pregnancy-associated associated plasma protein-a (PAPP-A) A) as a mortality predictor of long-term hemodialysis patients M. Kalousová, H. Benáková, A. A. Kuběna, S. Dusilová-Sulková, V. Tesař, T. Zima
More information( ) , (Donabedian, 1980) We would not choose any treatment with poor outcomes
..., 2013 Amgen. 1 ? ( ), (Donabedian, 1980) We would not choose any treatment with poor outcomes 1. :, 2. ( ): 3. :.,,, 4. :, [Biomarkers Definitions Working Group, 2001]., (William M. Bennet, Nefrol
More informationSt George & Sutherland Hospitals PERITONEAL DIALYSIS UNIT RENAL DEPARTMENT Workplace Instruction (Renal_SGH_WPI_097)
PERITONEAL DIALYSIS (PD) PERITONEAL EQUILIBRATION TEST (PET) Cross references NSW Health PD2007_036 - Infection Control Policy SGH-TSH CLIN027 - Aseptic Technique - Competency and Education Requirements
More informationDIALYSIS. Original Paper. Parvin Soltani, 1 Pardis Ketabi Moghaddam, 2 Farshid Haghverdi, 1 Ali Cheraghi 2
DIALYSIS A Randomized Clinical Trial of the Effect of Pentoxifylline on C-Reactive Protein Level and Dialysis Adequacy in Endstage Renal Disease Patients on Maintenance Hemodialysis Parvin Soltani, 1 Pardis
More informationAssociation between causes of peritoneal dialysis technique failure and all-cause mortality
www.nature.com/scientificreports Received: 27 September 2017 Accepted: 21 February 2018 Published: xx xx xxxx OPEN Association between causes of peritoneal dialysis technique failure and all-cause mortality
More informationHemodiafiltration in Europe : Trends, Practices, Outcomes & Perspectives
Hemodiafiltration in Europe : Trends, Practices, Outcomes & Perspectives Prof. Bernard Canaud Nephrology, Dialysis and Intensive Care Lapeyronie Hospital CHRU Montpellier - France Opening remarks and special
More informationBrief communication (Original)
Asian Biomedicine Vol. 8 No. 1 February 2014; 67-73 DOI: 10.5372/1905-7415.0801.263 Brief communication (Original) Long-term clinical effects of treatment by daytime ambulatory peritoneal dialysis with
More informationGambrosol Trio, clinical studies 91 Glitazone, malnutrition-inflammationatherosclerosis
Subject Index Acidosis, see Metabolic acidosis Activated carbon, sorbents 337 Adipokines adipose tissue and systemic inflammation 169 functions 167 169 prospects for study in renal patients 171 Adiponectin,
More informationLLL Session - Nutritional support in renal disease
ESPEN Congress Leipzig 2013 LLL Session - Nutritional support in renal disease Peritoneal dialysis D. Teta (CH) Nutrition Support in Patients undergoing Peritoneal Dialysis (PD) Congress ESPEN, Leipzig
More informationThe peritoneal equilibration test (PET) was developed THE SHORT PET IN PEDIATRICS. Bradley A. Warady and Janelle Jennings
Peritoneal Dialysis International, Vol. 27, pp. 441 445 Printed in Canada. All rights reserved. 0896-8608/07 $3.00 +.00 Copyright 2007 International Society for Peritoneal Dialysis THE SHORT PET IN PEDIATRICS
More informationImproved survival of type 2 diabetic patients on renal replacement therapy in Finland
Nephrol Dial Transplant (2010) 25: 892 896 doi: 10.1093/ndt/gfp555 Advance Access publication 21 October 2009 Improved survival of type 2 diabetic patients on renal replacement therapy in Finland Marjo
More informationThe Physiology of Peritoneal Dialysis As Related To Drug Removal
The Physiology of Peritoneal Dialysis As Related To Drug Removal Thomas A. Golper, MD, FACP, FASN Vanderbilt University Medical Center Nashville, TN thomas.golper@vanderbilt.edu Clearance By Dialysis Clearance
More informationWhen the organising committee of the VII National
http://www.revistanefrologia.com 2013 Revista Nefrología. Official Publication of the Spanish Nephrology Society Is peritoneal kinetics useful in clinical practice? In favour María J. Fernández-Reyes Luis
More informationFailure to obtain adequate rates of ultrafiltration (UF) is
Page 1 of 6 Peritoneal Dialysis International Peritoneal Dialysis International, inpress www.pdiconnect.com 0896-8608/16 $3.00 +.00 Copyright 2016 International Society for Peritoneal Dialysis ANALYSIS
More informationVolume Management 2/25/2017. Disclosures statement: Objectives. To discuss evaluation of hypervolemia in peritoneal dialysis patients
Volume Management Sagar Nigwekar MD, MMSc Massachusetts General Hospital E-mail: snigwekar@mgh.harvard.edu March 14, 2017 Disclosures statement: Consultant: Allena, Becker Professional Education Grant
More informationPART FOUR. Metabolism and Nutrition
PART FOUR Metaolism and Nutrition Advances in Peritoneal Dialysis, Vol. 19, 2003 Antonios H. Tzamaloukas, 1 Glen H. Murata, 2 Dorothy J. Vanderjagt, 3 Karen S. Servilla, 1 Roert H. Glew 3 Normalization
More informationOriginal Article ABSTRACT
Original Article Peritoneal Equilibration Test (PET) Analysis among Filipino Children on Chronic Peritoneal Dialysis at the National Kidney and Transplant Institute: A Cross-Sectional Study Elmer Kent
More informationImprovement in Pittsburgh Symptom Score Index After Initiation of Peritoneal Dialysis
Advances in Peritoneal Dialysis, Vol. 24, 2008 Matthew J. Novak, 1 Heena Sheth, 2 Filitsa H. Bender, 1 Linda Fried, 1,3 Beth Piraino 1 Improvement in Pittsburgh Symptom Score Index After Initiation of
More informationClinical Practice Guidelines : 3b - Peritoneal Dialysis. UK Renal Association Clinical Practice Guidelines 5th Edition 2007
Clinical Practice Guidelines : 3b - Peritoneal Dialysis UK Renal Association Clinical Practice Guidelines 5th Edition 2007 Prof Simon Davies Department of Nephrology University Hospital of North Staffordshire
More informationRole of High-sensitivity C-reactive Protein as a Marker of Inflammation in Pre-dialysis Patients of Chronic Renal Failure
ORIGINAL ARTICLE JIACM 2009; 10(1 & 2): 18-22 Abstract Role of High-sensitivity C-reactive Protein as a Marker of Inflammation in Pre-dialysis Patients of Chronic Renal Failure N Nand*, HK Aggarwal**,
More informationEarly Initiation of Dialysis Fails to Prolong Survival in Patients with End-Stage Renal Failure
J Am Soc Nephrol 13: 2125 2132, 2002 Early Initiation of Dialysis Fails to Prolong Survival in Patients with End-Stage Renal Failure JAMIE P. TRAYNOR,* KEITH SIMPSON,* COLIN C. GEDDES, CHRISTOPHER J. DEIGHAN,*
More informationHKMA Community Network HT Management Program
HKMA Community Network HT Management Program Peritoneal Dialysis and Hypertension Dr Siu Yui Pong, Gordon Review of Target BP in non-dialysis CKD patients What are the guidelines? DOQI (Dialysis Outcomes
More informationCHAPTER 6 PERITONEAL DIALYSIS. Neil Boudville. Hannah Dent. Stephen McDonald. Kylie Hurst. Philip Clayton Annual Report - 36th Edition
CHAPTER 6 Neil Boudville Hannah Dent Stephen McDonald Kylie Hurst Philip Clayton 213 Annual Report - 36th Edition ANZDATA Registry 213 Report STOCK AND FLOW AUSTRALIA Peritoneal dialysis was used to treat
More informationCorrelation of Residual Diuresis with MIS Score and Nutritional Status in Peritoneal Dialysis Patients: A Croatian Nationwide Study
BANTAO Journal 2015; 13(2): 59-67; doi:10.1515/bj-2015-0014 59 BJ BANTAO Journal Original article Correlation of Residual Diuresis with MIS Score and Nutritional Status in Peritoneal Dialysis Patients:
More informationAdequacy of automated peritoneal dialysis with and without manual daytime exchange: A randomized controlled trial
http://www.kidney-international.org & 2006 International Society of Nephrology original article Adequacy of automated peritoneal dialysis with and without manual daytime exchange: A randomized controlled
More informationKrediet slide di 18
1 di 18 Assessment of fluid status in PD patients Raymond T. Krediet, Amsterdam, Netherlands Chairs:Walther H. Boer, Utrecht, The Netherlands F. Fevzi Ersoy, Antalya, Turkey Prof. Raymond T. Krediet DDivision
More informationAutomated Peritoneal Dialysis is Suitable for Polycystic Kidney Disease Patients with End-Stage Renal Disease
Published online: June 20, 2015 2296 9705/15/0052 0140$39.50/0 This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC)
More informationExcess mortality due to interaction between proteinenergy wasting, inflammation and cardiovascular disease in chronic dialysis patients
7 Excess mortality due to interaction between proteinenergy wasting, inflammation and cardiovascular disease in chronic dialysis patients R. de Mutsert D.C. Grootendorst J. Axelsson E.W. Boeschoten R.T.
More informationCHAPTER 6 PERITONEAL DIALYSIS
CHAPTER 6 PERITONEAL DIALYSIS Fiona Brown Aarti Gulyani Hannah Dent Kylie Hurst Stephen McDonald PERITONEAL DIALYSIS ANZDATA Registry 11 Report STOCK AND FLOW AUSTRALIA Peritoneal dialysis was used to
More informationLeft ventricular hypertrophy: why does it happen?
Nephrol Dial Transplant (2003) 18 [Suppl 8]: viii2 viii6 DOI: 10.1093/ndt/gfg1083 Left ventricular hypertrophy: why does it happen? Gerard M. London Department of Nephrology and Dialysis, Manhes Hospital,
More informationA Case of Encapsulating Peritoneal Sclerosis Suspected to Result from the Use of Icodextrin Peritoneal Solution
Advances in Peritoneal Dialysis, Vol. 25, 2009 Hideki Kawanishi, Sadanori Shintaku, Masayuki Shishida, Misaki Morrishi, Shinichiro Tsuchiya, Kiyohiko Dohi A Case of Encapsulating Peritoneal Sclerosis Suspected
More informationPRESERVATION OF RESIDUAL RENAL FUNCTION IN DIALYSIS PATIENTS: EFFECTS OF DIALYSIS-TECHNIQUE RELATED FACTORS
Peritoneal Dialysis International, Vol. 21, pp. 52 57 Printed in Canada. All rights reserved. 0896-8608/00 $3.00 +.00 Copyright 2001 International Society for Peritoneal Dialysis PRESERVATION OF RESIDUAL
More informationCHAPTER 6 PERITONEAL DIALYSIS. Fiona Brown Aarti Gulyani Stephen McDonald Kylie Hurst Annual Report 35th Edition
CHAPTER 6 PERITONEAL DIALYSIS Fiona Brown Aarti Gulyani Stephen McDonald Kylie Hurst 212 Annual Report 35th Edition PERITONEAL DIALYSIS ANZDATA Registry 212 Report STOCK AND FLOW AUSTRALIA Peritoneal dialysis
More informationAcid-base profile in patients on PD
Kidney International, Vol. 6, Supplement 88 (23), pp. S26 S36 Acid-base profile in patients on PD SALIM MUJAIS Renal Division, Baxter Healthcare Corporation, McGaw Park, Illinois Acid-base profile in patients
More informationPART ONE. Peritoneal Kinetics and Anatomy
PART ONE Peritoneal Kinetics and Anatomy Advances in Peritoneal Dialysis, Vol. 20, 2004 Ewa E. Kaczmarek, Alicja E. Grzegorzewska Two Years on Continuous Ambulatory Peritoneal Dialysis Does It Change Peritoneal
More informationEFFECT OF ONLINE HAEMODIAFILTRATION ON ALL- CAUSE MORTALITY AND CARDIOVASCULAR OUTCOMES Ercan Ok, Izmir, Turkey
EFFECT OF ONLINE HAEMODIAFILTRATION ON ALL- CAUSE MORTALITY AND CARDIOVASCULAR OUTCOMES Ercan Ok, Izmir, Turkey Chair: Walter H. Hörl, Vienna, Austria Wojciech Zaluska, Lublin, Poland Prof Ercan Ok Division
More informationWhat is a PET? Although there are many types of pets, we will be discussing the Peritoneal Equilibration Test
1 2 3 What is a PET? Although there are many types of pets, we will be discussing the Peritoneal Equilibration Test 4 Background information about the PET 1983 Dr. Twardowski and colleagues began measuring
More informationTable 1 Baseline characteristics of 60 hemodialysis patients with atrial fibrillation and warfarin use
Table 1 Baseline characteristics of 60 hemodialysis patients with atrial fibrillation and warfarin use Baseline characteristics Users (n = 28) Non-users (n = 32) P value Age (years) 67.8 (9.4) 68.4 (8.5)
More informationJacek Waniewski, 1 Stefan Antosiewicz, 2 Daniel Baczynski, 2 Jan Poleszczuk, 1 Mauro Pietribiasi, 1 Bengt Lindholm, 3 and Zofia Wankowicz 2
Computational and Mathematical Methods in Medicine Volume 216, Article ID 824294, 1 pages http://dx.doi.org/1.1155/216/824294 Research Article Peritoneal Fluid Transport rather than Peritoneal Solute Transport
More informationEchocardiography analysis in renal transplant recipients
Original Research Article Echocardiography analysis in renal transplant recipients S.A.K. Noor Mohamed 1*, Edwin Fernando 2, 1 Assistant Professor, 2 Professor Department of Nephrology, Govt. Stanley Medical
More information