University of Medicine and Pharmacy (Romania) Nephrology and Internal Medicine Departament. University of Medicine and Pharmacy (Romania)

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1 Curriculum vitae PERSONAL INFORMATION Ionut Nistor WORK EXPERIENCE October 2009 Present Lecturer University of Medicine and Pharmacy (Romania) Nephrology and Internal Medicine Departament August 2011 Present Fellow European Renal Best Practice (Belgium) Methods Support Team ERBP, Ghent University. to assist guideline authors in preparation and updating of the ERBP guidelines EDUCATION AND TRAINING October 1998 August 2004 Medicine General University of Medicine and Pharmacy (Romania) October 2011 November 2014 PhD (Romania) PhD started in 2011 and finalized in November 2014, on the evidence for treatment of diabetic patients with developed CKD stage 3b/4/5. ADDITIONAL INFORMATION Expertise 1. MEDICAL AND HEALTH SCIENCES > Clinical medicine Urology and nephrology 2. MEDICAL AND HEALTH SCIENCES > Clinical medicine > Urology and nephrology Nephrology 3. MEDICAL AND HEALTH SCIENCES > Clinical medicine General and internal medicine 4. MEDICAL AND HEALTH SCIENCES > Clinical medicine > Other clinical medicine subjects Clinical trials 5. MEDICAL AND HEALTH SCIENCES > Clinical medicine > Other clinical medicine subjects > Medical statistics Epidemiology 6. MEDICAL AND HEALTH SCIENCES > Clinical medicine > Other clinical medicine subjects > Medical statistics Public health 7. MEDICAL AND HEALTH SCIENCES > Health sciences > Health policy and services Public health policies 8. MEDICAL AND HEALTH SCIENCES > Health sciences > Public and environmental health > Public health Chronic diseases Publications 1: Nistor I, Palmer SC, Craig JC, Saglimbene V, Vecchio M, Covic A, Strippoli GF. Convective versus diffusive dialysis therapies for chronic kidney failure: an updated systematic review of randomized controlled trials. Am J Kidney Dis ;63(6): Impact Factor 2: Nistor I, Palmer SC, Craig JC, Saglimbene V, Vecchio M, Covic A, Strippoli GFM. Haemodiafiltration, haemofiltration and haemodialysis for end-stage kidney disease. Cochrane Database of Systematic Reviews. CD doi: / cd pub Impact Factor 3: Covic A, Nistor I, Donciu MD, Dumea R, Bolignano D, Goldsmith D. Erythropoiesis-Stimulating Agents (ESA) for Preventing the Progression of Chronic Kidney Disease: A Meta-Analysis of 19 30/9/17 European Union, Page 1 / 5

2 Studies. Am J Nephrol. 2014;40(3): doi: / Impact Factor 4: Nistor I, Bararu I, Apavaloaie MC, Voroneanu L, Donciu MD, Kanbay M, Nagler EV, Covic A. Vasopressin receptor antagonists for the treatment of heart failure: a systematic review and meta-analysis of randomized controlled trials. Int Urol Nephrol Oct Impact Factor 5: Speeckaert M, Van Biesen W, Delanghe J, Slingerland R, Wiecek A, Heaf J, Drechsler C, Lacatus R, Vanholder R, Nistor I; for the European Renal Best Practice Guideline Development Group on Diabetes in Advanced CKD. Are there better alternatives than haemoglobin A1c to estimate glycaemic control in the chronic kidney disease population? Nephrol Dial Transplant Jan Impact Factor 6: Volovăt C, Cãruntu I, Costin C, Stefan A, Popa R, Volovăt S, Siriopol D, Voroneanu L, Nistor I, Segall L, Covic A. Changes in the histological spectrum of glomerular diseases in the past 16 years in the North-Eastern region of Romania. BMC Nephrol Jul 15;14:148. doi: / Impact Factor 7: Parfeni M, Nistor I, Covic A. A systematic review regarding the association of illness perception and survival among end-stage renal disease patients. Nephrol Dial Transplant Oct;28(10): doi: /ndt/gft Impact Factor 8: Goldsmith D, Covic A, Vervloet M, Cozzolino M, Nistor I; Chronic Kidney Disease-Mineral Bone Disease (CKD-MBD) working group and the European Renal Best Practice (ERBP) advisory board; Chronic Kidney Disease-Mineral Bone Disease CKD-MBD working group and the European Renal Best Practice ERBP advisory board. Should patients with CKD stage 5D and biochemical evidence of secondary hyperparathyroidism be prescribed calcimimetic therapy? An ERA-EDTA position statement. Nephrol Dial Transplant May;30(5): doi: /ndt/gfv050. Epub 2015 Mar 4; 3.58 Impact Factor 9: Nistor I, Bolignano D, Haller MC, Nagler E, van der Veer SN, Jager K, Covic A, Webster A, Van Biesen W. Why creating standardized core outcome sets for chronic kidney disease will improve clinical practice. Nephrol Dial Transplant Oct 23. pii: gfv365. [Epub ahead of print] PubMed PMID: Impact Factor 1: Segall L, Nistor I, Van Biesen W, Brown EA, Heaf JG, Lindley E, Farrington K, Covic A. Dialysis modality choice in elderly patients with end-stage renal disease: a narrative review of the available evidence. Nephrol Dial Transplant Dec 15. pii: gfv411. [Epub ahead of print] Review. PubMed PMID: Impact Factor 2: Burlacu A, Siriopol D, Voroneanu L, Nistor I, Hogas S, Nicolae A, Nedelciuc I, Tinica G, Covic A. Atherosclerotic Renal Artery Stenosis Prevalence and Correlations in Acute Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Interventions: Data From Nonrandomized Single-Center Study (REN-ACS) A Single Center, Prospective, Observational Study. J Am Heart Assoc Oct 12;4(10):e doi: /JAHA PubMed PMID: Impact Factor 3: Chazot C, Farrington K, Nistor I, Van Biesen W, Joosten H, Teta D, Siriopol D, Covic A. Pro and con arguments in using alternative dialysis regimens in the frail and elderly patients. Int Urol Nephrol Nov;47(11): doi: /s Epub 2015 Sep 16. PubMed PMID: Impact Factor 4: Onofriescu M, Siriopol D, Voroneanu L, Hogas S, Nistor I, Apetrii M, Florea L, Veisa G, Mititiuc I, Kanbay M, Sascau R, Covic A. Overhydration, Cardiac Function and Survival in Hemodialysis Patients. PLoS One Aug 14;10(8):e doi: /journal.pone ecollection PubMed PMID: ; PubMed Central PMCID: PMC Impact Factor 30/9/17 European Union, Page 2 / 5

3 5: Guideline development group. Clinical Practice Guideline on management of patients with diabetes and chronic kidney disease stage 3b or higher (egfr <45 ml/min). Nephrol Dial Transplant May;30 Suppl 2:ii doi: /ndt/gfv100. PubMed PMID: Impact Factor 6: Coentrão L, Van Biesen W, Nistor I, Tordoir J, Gallieni M, Marti Monros A, Bolignano D. Preferred haemodialysis vascular access for diabetic chronic kidney disease patients: a systematic literature review. J Vasc Access Jul-Aug;16(4): doi: /jva Epub 2015 Feb 3. PubMed PMID: Impact Factor 7: Voroneanu L, Siriopol D, Nistor I, Apetrii M, Hogas S, Onofriescu M, Covic A. Superior predictive value for NTproBNP compared with high sensitivity ctnt in dialysis patients: a pilot prospective observational study. Kidney Blood Press Res. 2014;39(6): doi: / PubMed PMID: Impact Factor 8: Nagler EV, Vanmassenhove J, van der Veer SN, Nistor I, Van Biesen W, Webster AC, Vanholder R. Diagnosis and treatment of hyponatremia: a systematic review of clinical practice guidelines and consensus statements. BMC Med Dec 11;12:1. doi: /s Review. PubMed PMID: ; PubMed Central PMCID: PMC Impact Factor 9: Ballinger AE, Palmer SC, Nistor I, Craig JC, Strippoli GF. Calcimimetics for secondary hyperparathyroidism in chronic kidney disease patients. Cochrane Database Syst Rev. 2014;12:CD doi: / CD pub2. Epub 2014 Dec 9. Review. PubMed PMID: Impact Factor 10: Van Huffel L, Tomson CR, Ruige J, Nistor I, Van Biesen W, Bolignano D. Dietary restriction and exercise for diabetic patients with chronic kidney disease: a systematic review. PLoS One Nov 25;9(11):e doi: /journal.pone ecollection Review. PubMed PMID: ; PubMed Central PMCID: PMC Impact Factor 11: Siriopol D, Canaud B, Stuard S, Mircescu G, Nistor I, Covic A. New insights into the effect of haemodiafiltration on mortality: the Romanian experience. Nephrol Dial Transplant Feb;30(2): doi: /ndt/gfu347. Epub 2014 Nov 13. PubMed PMID: Impact Factor 12: Couchoud C, Bolignano D, Nistor I, Jager KJ, Heaf J, Heimburger O, Van Biesen W; European Renal Best Practice (ERBP) Diabetes Guideline Development Group. Dialysis modality choice in diabetic patients with end-stage kidney disease: a systematic review of the available evidence. Nephrol Dial Transplant Feb;30(2): doi: /ndt/gfu293. Epub 2014 Sep 23. Review. PubMed PMID: Impact Factor 13: Segall L, Nistor I, Covic A. Heart failure in patients with chronic kidney disease: a systematic integrative review. Biomed Res Int. 2014;2014: doi: /2014/ Epub 2014 May 15. Review. PubMed PMID: ; PubMed Central PMCID: PMC Impact Factor 14: Kanbay M, Siriopol D, Nistor I, Elcioglu OC, Telci O, Takir M, Johnson RJ, Covic A. Effects of allopurinol on endothelial dysfunction: a meta-analysis. Am J Nephrol. 2014;39(4): doi: / Epub 2014 Apr 17. PubMed PMID: Impact Factor 15: Onofriescu M, Hogas S, Voroneanu L, Apetrii M, Nistor I, Kanbay M, Covic AC. Bioimpedance-guided fluid management in maintenance hemodialysis: a pilot randomized controlled trial. Am J Kidney Dis Jul;64(1): doi: /j.ajkd Epub 2014 Feb 28. PubMed PMID: Impact Factor 16: Segall L, Moscalu M, Hogaş S, Mititiuc I, Nistor I, Veisa G, Covic A. Protein-energy wasting, as well as overweight and obesity, is a long-term risk factor for mortality in chronic hemodialysis patients. 30/9/17 European Union, Page 3 / 5

4 Int Urol Nephrol Mar;46(3): doi: /s Epub 2014 Jan 29. PubMed PMID: Impact Factor 17: Arnouts P, Bolignano D, Nistor I, Bilo H, Gnudi L, Heaf J, van Biesen W. Glucose-lowering drugs in patients with chronic kidney disease: a narrative review on pharmacokinetic properties. Nephrol Dial Transplant Jul;29(7): doi: /ndt/gft462. Epub 2013 Dec 8. Review. PubMed PMID: Impact Factor 18: Nagler EV, Webster AC, Bolignano D, Haller MC, Nistor I, van der Veer SN, Fouque D, Van Biesen W. European Renal Best Practice (ERBP) Guideline development methodology: towards the best possible guidelines. Nephrol Dial Transplant Apr;29(4): doi: /ndt/gft407. Epub 2013 Sep 29. Review. PubMed PMID: Impact Factor 19: Palmer SC, Nistor I, Craig JC, Pellegrini F, Messa P, Tonelli M, Covic A, Strippoli GF. Cinacalcet in patients with chronic kidney disease: a cumulative meta-analysis of randomized controlled trials. PLoS Med. 2013;10(4):e doi: /journal.pmed Epub 2013 Apr 30. Review. PubMed PMID: ; PubMed Central PMCID: PMC Impact Factor 20: Onofriescu M, Mardare NG, Segall L, Voroneanu L, Cuşai C, Hogaş S, Ardeleanu S, Nistor I, Prisadă OV, Sascău R, Covic A. Randomized trial of bioelectrical impedance analysis versus clinical criteria for guiding ultrafiltration in hemodialysis patients: effects on blood pressure, hydration status, and arterial stiffness. Int Urol Nephrol Apr;44(2): doi: /s y. Epub 2011 Jun 19. PubMed PMID: Impact Factor 21: Voroneanu L, Cusai C, Hogas S, Ardeleanu S, Onofriescu M, Nistor I, Prisada O, Sascau R, Goldsmith D, Covic A. The relationship between chronic volume overload and elevated blood pressure in hemodialysis patients: use of bioimpedance provides a different perspective from echocardiography and biomarker methodologies. Int Urol Nephrol Sep;42(3): doi: /s y. Epub 2010 Jun 4. PubMed PMID: Impact Factor 22: Segall L, Mardare NG, Ungureanu S, Busuioc M, Nistor I, Enache R, Marian S, Covic A. Nutritional status evaluation and survival in haemodialysis patients in one centre from Romania. Nephrol Dial Transplant Aug;24(8): doi: /ndt/gfp110. Epub 2009 Mar 17. PubMed PMID: Impact Factor Projects Memberships , Scientific Secretary of ERA-EDTA CME COURSE Renal Failure Academy, 2011 present, Board Member European Renal Best Practice ERBP guidelines 2013-present, Board Member Romanian Society of Nephrology Starting from October 2014: Associate Editor for Clinical Kidney Journal, the second official journal of European Society of Nephrology (ERA-EDTA). Reviewer for: International Urology and Nephrology (nephrology) Nephrology Dialysis Transplantation Cochrane Database of Systematic Reviews Archives of Medical Science American Journal of Kidney Disease 30/9/17 European Union, Page 4 / 5

5 Hemodialysis International Other Relevant Information 30/9/17 European Union, Page 5 / 5

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