Allegiance Wellness Center

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1 Allegiance Wellness Center San Diego Pain Management Center Point Loma Parkinson s Disease Support Group!! The medical benefits of Cannabis!! Bert Telles! Ph: ! October 2, 2013

2 Disclaimer: SDPMC/AWC is not run, operated, directed, or managed by a physician or a licensed professional, and nothing in this document constitutes professional or medical advice. Reviewing the information is no substitute for consulting with your physician. SDPMC/AWC urges you to consult with your physician before beginning any treatment or regiment to treat your ailments, including medical cannabis.

3 Cannabis and Parkinson s Youtube

4 The Medical Benefits of Cannabis for Parkinson s Disease Reduce Tremors! Jerking Reduced! Reduce Pain! Reduce Stress/More Relaxed! Uplifting! Reduce Anxiety and Depression/Less Nervousness! Increase Appetite! Better Sleep! Reduce Anti-Depressants! * Cannabis use dates back 4000 years with either medicinal or spiritual uses in the Hindu and Chinese cultures.

5 How it works! Cannabinoids -THC, CBD, CBN and the Endocannabinoid system. 85 Cannabinoides in cannabis! Cannabinoid receptors in the brain (CB1 Neurological System)! Cannabinoid receptors in the body (CB2 Immune System)! CBD reduces the effect of THC! Anti-Spasmodic! Anti-inflammatory! Appetite Stimulant! CBD beneficial in short term memory loss

6 Cannabinoids and their Treatment

7 Dosing and Forms of Treatment Method Onset Peak Duration Inhalation Smoking or vaporizing, the most common method Minutes 30 minutes 1-4 hours Topical - Salves, Creams, Concentrates, Oral Edibles, drinks Pills, Capsules Sublingual Using tablets, strips or sprays under the tongue 5-60 minutes 2-3 hours 4-8 hours minutes 2-3 hours 6-8 hours 5-60 minutes 1-2 hours 1-4 hours

8 How much THC should I consume?! Cost is a factor!! The FDA guidelines for prescribing Dronabinol (Marinol), which is the synthetic form of THC, is 2.5 to 15mg of THC, 3 times a day. It is important to remember that every individual will have a different dosage need, independent of body size and tolerance.! The research studies on CBD show from 100mg to 300mg and more per day is beneficial. We see noticeable effects from 7-15mg and up, 3 times per day.

9 Administration and Adverse Reactions! THC is psychoactive and will make you "high"! CBD is non-psychoactive and will not make you "high"! Euphoria! Dizziness! Too much can cause anxiety! Sedation/Relaxation! Unease! Can't overdose! Lasts for 4 hours! If too much, just lie down and go to sleep! No adverse side effects or drug interaction

10 Insurance, Politics, Reasons Dr's don't prescribe, FDA Approval Doctors don't know! Want research! Still Federally Illegal! Not FDA approved! Politics "Scared"! Insurance companies are driven by Pharma

11 Medical/Clinical Research Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil. - (Sept 2008) CBD reduced the psychotic symptoms of Parkinson's Disease! Consroe P, Sandyk R, Snider SR. (Nov1986) Shown Improvement in Dystonia or movement disorder, in muscle contractions, twisting and repetitive movements or abnormal postures from 20 to 50%. Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Investigación en Neuroquímica, Facultad de Medicina, Universidad Complutense, Madrid, Spain. (Aug 2011) Given its antioxidant properties and its ability to activate CB(2) but to block CB(1) receptors, Δ(9)-THCV has a promising pharmacological profile for delaying disease progression in Parkinson's Disease and also for improving parkinsonian symptoms.! JW Goethe University, Section Molecular Neurogenetics, Frankfurt am Main, Germany. (2006) The article will review all data about the relationship between PD and the cannabinoid system including: i) the usefulness of cannabinoid-related compounds to alleviate some PD symptoms; ii) that cannabinoid-based compounds might provide protection against the progression of neuronal injury characteristic of this disease; iii) the influence of cannabinoids on local inflammatory events associated with the pathogenesis in PD. Collectively, all these evidence support that the management of the cannabinoid system might represent a new approach to the treatment of PD.! Faculty of Medicine and Dentistry, Department of Pharmacology, University of the Basque Country Leioa, Spain. (June 2012) It has been suggested that endocannabinoid system may constitute an important component in new therapeutic approaches to the treatment of motor disturbances (as happens in Parkinson's disease). In this article they review studies supporting the endocannabinoid modulation of dopaminergic motor circuits.

12 Next Steps: How to get some! Medical Marijuana Doctor Recommendation or Caregiver! Not required for CBD only! Sign up and Join a Collective! You will need a photo or copy of your Doctor Recommendation for verification! You will need a picture of ID! On-line ordering from a delivery service or storefront when available.

13 Medical Marijuana Doctor Recommendation Dr. John Welsh! Medicann! Appointments (866) ! 3990 Old Town Avenue #C-304! San Diego CA 92110

14 Thank you for your consideration!

15 Did You Know?

16 Legal Structure of the Business Allegiance Wellness Center is a Mutual Benefit Non-profit Corporation as required by California Law A collective is a corporate entity (Not a person) that cultivates, possesses and transports marijuana for distribution to its members (all are qualified patients) on a non-profit basis, similar to an electric co-op A collective exists for the purpose of benefiting its fellow members by cultivation and sharing of marijuana among a group of individual qualified medical patients in a manner that complies with California law

17 Proposition The Compassionate Use Act of 1996! Decriminalized the cultivation and use of marijuana by seriously ill individuals upon a physician s recommendation! Ensures that seriously ill Californians have the right to obtain and use marijuana for medical purposes! The patient has been recommended by a physician who has determined that the person s health would benefit from the use Ensures that patients and their primary caregivers who obtain and use marijuana for medical purposes are not subject to criminal prosecution or sanction

18 Senate Bill The Medical Marijuana Program Act Became law on January 1, 2004 Requires the California Department of Public Health to establish and maintain a statewide identification card system Help law enforcement officers identify and verify that cardholders are able to cultivate, possess, and transport certain amounts of marijuana without being subject to arrest

19 A Brief History of the Medical Marijuana Industry Medical Marijuana Collectives have existed legally in California for 17 years and approximately 160 operate in San Diego California has set the tone for this $14B market morphing into a fullfledged industry A 2010 ABC News/Washington Post poll showed 81% of Americans support marijuana for medical use. And in 2013, 20 states and the District of Colombia have legalized medical marijuana, 2 states have legalized for recreational use and 15 other states have bills or initiatives in the works for some sort of model for distribution.

20 A Brief History of the Medical Marijuana Industry - Cont d California State Board of Equalization estimates the California marijuana crop the state s largest cash crop, 4x bigger than the states wine industry In February 2007, the California State Board of Equalization issued a Special Notice confirming its policy of taxing medical marijuana transactions That businesses engaging in such transactions hold a Seller s Permit.! Seller s Permit does not allow individuals to make unlawful sales, but instead merely provides a way to remit any sales and use taxes due the State Board Of Equalization

21 The State Law - Possession and Cultivation Guidelines Qualified patients may possess up to 16 oz. of dried or 2 oz. of concentrate of medical marijuana per person Qualified patients may also cultivate 24 un-harvested plants grown in an area no more than 64 square feet If a person is acting as primary caregiver to more than one patient he or she may aggregate the possession and cultivation limits for each patient Similarly, collectives and cooperatives may cultivate and transport marijuana in aggregate amounts tied to its membership numbers

22 Industry Professionals Center for Medical Cannabis Research (UCSD) The Scripps Research Institute Society of Cannabis Clinicians

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