CURRICULUM VITAE DR. N. SATHEESH KUMAR,

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1 CURRICULUM VITAE DR. N. SATHEESH KUMAR, M.Pharm., Ph.D., Assistant Professor Department of Pharmaceutical Analysis National Institute of Pharmaceutical Education and Research [NIPER]-H Balanagar, Hyderabad , India. Mobile: ACADEMIC PROFILE: Ph.D from Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India [ ]. Master of Pharmacy (Pharmaceutical Analysis) from TN. Dr. MGR Medical University, Chennai, India [ ]. Bachelor of Pharmacy from TN. Dr. MGR Medical University, Chennai, India [ ]. CURRENT STATUS: Working as a Assistant Professor in Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research [NIPER] - H, Balanagar, Hyderabad. [Dec till date] PROFESSIONAL EXPERIENCES: 1. Worked as a Lecturer in Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research [NIPER] - H, Balanagar, Hyderabad. [Nov Dec 2012] 2. Worked as Assistant Professor, Dayananda Sagar College of Pharmacy, Bangalore [Feb 2010 Nov 2010] 3. Worked as Senior Research Fellow - Department of Pharmaceutical Technology, Jadavpur University, Kolkata.[June 2006-Jan 2010] SPONSORED RESEARCH PROJECTS (SANCTIONED/APPROVED): S. No Funding Agency (Scheme) 1 Department of Science and Technology, Government of India (DST Young Scientists Scheme) 2 Council of Scientific & Industrial Research [CSIR] Status of the Project (Registration No.) Recommended [File No. SERB/LS- 323/2013] Recommended File No: 60(8416)/11 Role Principal Investigator Principal Investigator PROJECT GRANTS- UNDER REVIEW: S. No Funding Agency (Scheme) Role 1 ICMR Principal Investigator 2 DST Principal Investigator 1 P a g e

2 AWARDS RECEIVED: DST Young Scientist Project Grant International Travel Award received from Department of Science & Technology [DST] & ICMR for attending the International conference at Chicago, USA, October 14-18, Travel Award received from Department of Science & Technology [DST] & Jadavpur University for attending the International conference at São Paulo, Brazil, September 16-19, Travel Award received from Jadavpur University for attending the International Conference on Herbal Medicine at Bangalore, India, 26-29, February Awarded as a Senior Research Fellow funded by Dabur Research Foundation (DRF), New Delhi, India ( ). Research Fellow from the University Grant Commission [UGC], Govt of India Best Paper award for an article entitled Plant Made Pharmaceuticals (PMPs) - Development of Natural Health Products from Bio-Diversity. Authored by N. Satheesh Kumar and Micheal Heinrich, Indian Journal of Pharmaceutical Education & Research, Vol. 42(2), 2008, Reviewer of Journal of Ethnopharmacology, Elsevier sciences Reviewer of Acta chromatograpia Reviewer of Journal of Planar Chromatography HIGHLIGHTS OF RESEARCH EXPERIENCE AND SKILLS ACQUIRED: Method development & validation for various API by different analytical techniques Stability Indicating assay methods & Impurity profiling Metabolomics In vitro & in vivo pharmacological screening of various natural product isolates Bio assay guided isolation techniques. Bioanalysis Nano drug delivery system Phytopharmaceuticals RESEARCH GROUP: One student is working for his Doctoral Research 8 Students have completed their 1 year M.S (Pharm) projects 4 Students are working on their 1 year M.S (Pharm) projects BOOK CHAPTERS: N. Satheesh Kumar et al. Tests for antioxidant activity and their relevance to herbal medicinal products. In: Evaluation of Herbal Medicinal Products. Pharmaceutical Press, Royal Pharmaceutical Society Publishers, London, 2009, p ,isbn N. Satheesh Kumar et al. Herbal medicinal products affecting memory and cognitive disorders, In: Evaluation of Herbal Medicinal Products. Pharmaceutical Press, Royal Pharmaceutical Society Publishers, London, 2009, p , ISBN P a g e

3 RESEARCH PUBLICATIONS: Articles in Refereed Journals 1. S. Shantikumar, G. Sreekanth, KV. SurendraNath, S. JaferValli, N. Satheeshkumar. Compatibility study between Sitagliptin and pharmaceutical excipients used in solid dosage forms. Journal of Thermal Analysis and Calorimetry (Accepted 2013). Impact factor: N. Satheesh Kumar, N. Nisha. Phytomedicines as Potential Inhibitors of β Amyloid Aggregation: Significance to Alzheimer's Disease. Chinese Journal of Natural Medicines, Elsevier Sciences [Accepted 2013]. 3. N. Satheesh Kumar, N. Nisha, N. Sonali, J. Nirmal, GK. Jain, V. Spandana. Analytical Profiling of Bioactive Constituents from Herbal Products, using Metabolomics - A Review. Natural Product Communications, 2012, 7(8), Impact factor: P.K. Mukherjee, N. Satheeshkumar, P. Venkatesh and M. Venkatesh. Lead Finding for Acetyl Cholinesterase Inhibitors from Natural Origin: Structure Activity Relationship and Scope. Mini-Reviews in Medicinal Chemistry, 2011,11(3), Impact factor: N. Satheesh Kumar, Narayanan Nisha, Jayabalan Nirmal, Narayanan Sonali, J Bagyalakshmi. HPLC Determination of Pitavastatin Calcium in Pharmaceutical Dosage Forms. Pharm Anal Acta, 2011, 2(2): N. Satheesh Kumar, Pulok K. Mukherjee, S. Bhadra and B. P. Saha. Acetylcholinesterase enzyme inhibitory potential of standardized extract of Trigonella foenum graecum L and its constituents. Phytomedicine, 2010, 17 (3-4), Impact factor: N. Satheesh Kumar, P.K Mukherjee, S. Bhadra, B.P. Saha, B.C. Pal. Acetylcholinesterase inhibitory potential of a carbazole alkaloid, mahanimbine, from Murraya koenigii. Phytotherapy Research, 2010, 24(4), Impact factor: N. Satheesh Kumar and J. Baghyalakshmi. Determination and Quantification of Pitavastatin Calcium in Tablet Dosage Formulation by HPTLC Method. Analytical Letters, 40: , Impact factor: S. Bhadra, P. K. Mukherjee, N. Satheesh Kumar, A. Bandyopadhyay. Anticholinesterase activity of standardized extract of Illicium verum Hook. f. fruits Fitoterapia, 82(3): Impact factor: P. Venkatesh, P. K Mukherjee, N. Satheesh Kumar, A. Bandyopadhyay, H. Fukui, H. Mizuguchi, N. Islam. Anti-allergic activity of standardized extract of Albizia lebbeck with reference to catechin as a phytomarker. Immunopharmacology And Immunotoxicology, 2010; 32(2): Impact factor: D. Mukherjee, N. Satheesh Kumar, T. Khatua, P. K. Mukherjee. Rapid Validated HPTLC Method for Estimation of Betulinic acid in Nelumbo nucifera (Nymphaeaceae) rhizome extract. Phytochemical Analysis. 2010, 21(6): Impact factor: P. Venkatesh, P. K Mukherjee, N. Satheesh Kumar, N.K.Neema, A. Bandyopadhyay, H. Fukui, H.Mizuguchi. Mast cell stabilization and antihistaminic potentials of Curculigo orchioides rhizomes. Journal of Ethnopharmacology, 2009, 126, 3, Impact factor: P a g e

4 13. P. K. Mukherjee, Venkatesan Kumar, N. Satheesh Kumar, Micheal Heinrich. The Ayurvedic medicine Clitoria ternatea--from traditional use to scientific assessment. Journal of Ethnopharmacology, 2008,120(3), Impact factor: V. Kumar, K. Mukherjee, N. Satheesh Kumar, M. Mal, and P. K. Mukherjee. Validation of HPTLC method for the analysis of taraxerol in Clitoria ternatea. Phytochemical analysis, 2008, 19, Impact factor: P. K. Mukherjee, Atish K Sahoo, Nisha Narayanan, N. Satheesh Kumar, S. Ponnusankar. Lead finding from Medicinal plants with hepatoprotective potentials, Expert Opinion on Drug Discovery, 2009, 4, Impact factor: Atish K Sahoo, Nisha Narayanan, N Satheesh Kumar, S Rajan and P. K. Mukherjee, Phytochemical and therapeutic potentials of Morinda tinctoria Roxb. (Indian mulberry) Oriental Pharmacy and Experimental Medicine (2), P. K. Mukherjee, N. Satheesh Kumar and Micheal Heinrich. Plant Made Pharmaceuticals (PMPs) - Development of Natural Health Products from Bio-Diversity., Indian Journal of Pharmaceutical Education & Research, Vol. 42(2), 2008, PK Mukharjee, NS Kumar, V Kumar. Exploring phytomedicines from biological diversity, Mesra , Ranchi (India), 2007, RESEARCH PUBLICATIONS (MANUSCRIPTS AT DIFFERENT STAGES OF PREPARATION): 1. N. Satheesh Kumar et al. A Quality by design based HPLC method for estimation of Paliperidone in pharmaceutical dosage forms. Journal of Pharmaceutical and Biomedical Analysis (Under Review). 2. Satheesh Nanjappan, Vudataneni Spandana, Saladi Shantikumar and Ragampeta Srinivas. Experimental design approach to optimize stability indicating LC method for the determination of Naftopidil in its bulk and tablet dosage form. Chromatography Research International (Under Review). 3. "N. Satheesh Kumar et al. A Novel RP-HPLC Method for the Simultaneous Estimation of Some Drugs Used in Cardiovascular Therapy. Chromatographia (Under Review). 4. N. Satheesh Kumar et al. A Stability Indicating RP-HPLC Method For Ambrisentan-An Endothelin Receptor Antagonist" Journal of Chromatographic Science (Under Review). 5. N. Satheesh Kumar et al. Pioglitazone: A Review of Analytical Methods. Analytical Letters (Under Review). 6. N. Satheesh Kumar et al. Development of Validated Stability indicating Assay method for Simultaneous Estimation of Metformin hydrochloride and Vildagliptin by RP-HPLC. Drug Research (Under Review). 4 P a g e

5 SYMPOSIUMS/CONFERENCES PRESENTATIONS AND PARTICIPATIONS: 1. A Validated Stability-indicating RP-LC study for Naftopidil in Pharmaceutical Formulation. N. Satheesh Kumar, Vudataneni Spandana, R. Srinivas. American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition, McCormick Place, Chicago, USA, October 14 18, Determination of mahanimbine in Murraya Koenigii by HPTLC. Satheesh Kumar. N, Mukherjee P. K. International Symposium for High-Performance Thin-Layer Chromatography, 06th - 08th July 2011, Basel, Switzerland. 3. Acetylcholinesterase inhibitors from Trigonella foenum graecum L. Satheesh Kumar. N, Kumar V, Mukherjee P. K XX Simpósio de Plantas Medicinais do Brasil XX Congresso Internacional de Etnofarmacologia São Paulo, Brazil, September 16-19, Mahanimbine in Murraya Koenigii Marker Analysis and acetyl cholinesterase enzyme Inhibition. Satheesh Kumar. N, Mukherjee PK.International Herbal Conference 2009, Bangalore, February 26-29, In vitro Acetylcholinesterase Inhibitory Activity of Mahanimbine in Murraya Koenigii. N. Satheesh Kumar, P.K. Mukherjee. 9th International Conference on Alzheimer's and Parkinson's Diseases. Prague, Czech Republic, March 11-15, Baliospermum Montanum Inhibited Compound 48/80 Induced Systemic Anaphylaxis in mice Venkatesh P, Satheesh Kumar, Venkatesh M. A International conference on Herbal Medicine Evaluation of Quality, Efficacy and Safety at Bangalore February 26-29, 2009; p Trigonelline in Trigonella foenum graecum - Marker analysis and acetyl cholinesterase enzyme inhibition. N. Satheesh. Kumar, P.K. Mukherjee, Jadavpur University, India, 18th Neuropharmacology conference, Washington, November 12-14, Immunomodulatory Activity of Standardized Extract of Nelumbo Nucifera Gaertn. (Nymphaceae) Rhizome and Seed. Debajyoti Mukherjee, Tarak Nath Khatua, N.Satheesh Kumar,. A International conference on Herbal Medicine Evaluation of Quality, Efficacy and Safety at Bangalore February 26-29, 2009; p P a g e

Summary and Conclusion

Summary and Conclusion Chapter 7 7.1. Summary 7.2. Conclusion 100 7.1. Summary Evaluation of anti-aging efficacy of herbal drugs has become one of the major concerns with tremendous increase in the application of traditional