Relationships between Basal Metabolic Rate and Reproductive Output and Visceral Organs in Lactating Mice

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1 Chinese Journal of Zoology ~ KM Mus musculus BMR Pearson BMR BMR BMR BMR BMR Q Q494 A Relationships between Basal Metabolic Rate and Reproductive Output and Visceral Organs in Lactating Mice ZHAO Zhi-Jun CAO Jing LI Lu-Sheng School of Agricultural ScienceLiaocheng UniversityLiaocheng China Abstract The basal metabolic rate BMR was measured in the female KM mice Mus musculus prior to reproduction and at late lactation using a closed-circuit respirometer. Relationships between BMRreproductive output and visceral organs were examined using Regression residuals and Pearson correlation analyses. It was showed that the BMR was 66% higher at late lactation than that prior to reproduction. There was no significant correlation between the BMR prior to reproduction and reproductive output. Howeverthe BMR at late lactation was positively correlated with maternal body massfood intakelitter size and massas well as the weight of visceral organs and gastrointestinal tractwithin which the correlation between BMR and gastrointestinal tract was higher relative to the other visceral organs. Our data have provided support for the hypothesis that animals with high BMR during lactation might have a greater capacity for absorbing energyand consequently have more energy export for reproductive output. Key words Basal metabolic rate Lactation Mice Reproduction 4-5 Thompson basal metabolic ratebmr No No. J09LC70 No zhaozj73@ yahoo. com. cn

2 40 Chinese Journal of Zoology 45 BMR Harvey 6 BMR 11 d 31 n = BMR 3 17 early lactationearly L BMR late lactationlate L 7 17 BMR BMR BMR prior to reproductionpri BMR BMR BMR at late lactation LL BMR 1. 2 BMR LKOH CO 2 BMR BMR 8-9 BMR 30 ± 1 14 ± 1 4 h 1 h 5 BMR min 60 min Selman MF1 Mus BMR ml O 2 / h musculus 1. 3 brown adipose tissue BMR BAT BMR 11 BMR 15 BMR BMR KM repeated measures BMR BMR Pearson BMR BMR BMR BMR BMR BMR / ~ KM SCXK BMR cm 18 cm 16 cm 12L 12D 23 ± SPSS ± Mean ± SE P P ~ 8 9 ~ 17 F = 3. 6P < A BMR 76. 3

3 4 41 ± 1. 7 ml O 2 / h ± 3. 0 ml 2A O 2 / h 66% F 130 = P < BMR Fig. 1 1 KM A B C D Maternal body mass A food intake B litter size C and litter mass D during lactation in KM mice 2. 2 BMR 3 4A BMR ± 0. 5 g3 ~ 7 8 ~ B ± 0. 8 g 3 ~ 17 F = 4. 6 P < B BMR BMR 4D 2B 2. 4 BMR BMR 2. 3 BMR 1 BMR BAT 3 ~ BMR ± ± ~ 17 BMR ± 0. 5 F = 6. 4P < C BMR 4C ± 1. 4 g 1. 6 F = P < D BMR

4 42 Chinese Journal of Zoology 45 2 KM A B Fig. 2 Relationships between basal metabolic rate BMR and body mass A and asymptotic food intake B in lactating KM mice Pri. LL. Pri. Prior to reproduction LL. Late lactation. 3 KM 21 g / d g BMR 17 - BMR KM BMR BMR 66% BMR MF1 3 Mesocricetus KM auratus 10 BMR BMR Phodopus sungorus Monodelphis domestica Tenrec 19 - ecaudatus BMR Thompson 21 BMR BMR 3 KM Fig. 3 Relationships between basal metabolic rate BMR prior to reproduction and at late lactation in KM mice Pri BMR. LL BMR. Pri. Prior to reproduction LL. Late lactation. Kleiber KM MF1 BMR Thompson 21 BMR Poppitt 22 BMR BMR

5 KM A B C D Fig. 4 Relationships between litter size and BMR prior to reproduction A and at late lactation B and relationships between litter mass and BMR prior to reproduction C and at late lactation D in KM mice Pri BMR LL BMR Early L Late L Pri Prior to reproduction LL Late lactation. Early L Litter size at early lactation Late L Litter size at late lactation KM BMR BMR MF KM Mirotus mandarinus KM BMR BMR MF1 KM 7 Johnson 7 BMR MF

6 44 Chinese Journal of Zoology 45 BMR 17 Table 1 1 KM Relationships between basal metabolic rate BMR and organs in lactating KM mice BMR Carcass BAT Heart Liver Lung Spleen Kidney Mammary gland Stomach SI LI Carcass * BAT Heart Liver * * * Lung * Spleen Kidneys * Mammary gland * Stomach * Small intestine Large intestine * Caecum * R 2 BMR BAT * P < 0. 05P < The data was the coefficient of correlation between the variables R 2. BMR Basal metabolic rate BAT Brown adipose tissue * < P < BMR BMR MF BMR 2 ~ 3 8 ~ 10 BMR 5% 31 BMR 3716 BMR KM BMR BMR BMR 0. 8 P < BMR 1 KM BMR BMR BMR BMR Speakman J RKrol E. Limits to sustained energy intake IX a review of hypotheses. J Comp Physiol B Speakman J RMcQueenie J. Limits to sustained metabolic rate The link between food intakebasal P

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RESEARCH ARTICLE Energy budget during lactation in striped hamsters at different ambient temperatures

RESEARCH ARTICLE Energy budget during lactation in striped hamsters at different ambient temperatures 988 The Journal of Experimental iology 214, 988-99 211. Published by The Company of iologists Ltd doi:1.1242/jeb.4939 RESERCH RTICLE Energy budget during lactation in striped hamsters at different ambient