Risk Analysis Activity APPENDIX 19. Consumer. Since 2003, Food Safety Policy and implementation have been campaigned in Thailand

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1 Since 2003, Safety Policy and implementation have been campaigned Mr. Mongkol Chenchittikul Director of Bureau of Quality and Safety of Department of Medical Sciences, Ministry of Pubic Health, Thailand Dr. Songsak Srianujata Senior Advisor, Safety Institute of Nutrition, Mahidol University Safety strategies and road map covering the food chain were developed In 2008, Law to establish National Committee on was issued 2 Regulatory measure comply with international standard Standardized of 1.Imported 2.Domestic 3.Exported 1 Strengthen on 2 Improve 3 Improve 4 Improve 5 consumer s human lab Safety potential resource potential monitoring work Risk management process 1.Stimulante system public relate 1.Quarantine 1.Educate lab. 2.Logo working announce 2.Mobile lab. Control imported food Quarantine Control food production Farm/ Factory Transportation/Logistic 3.Co-operateoperate government / private sector for sale (consumer protection) 1.Market food test kits 2.Restaurant clean food good taste 3.Street food vender 4.Check FDA label personal 2.Network & linking 3.Mini FDA volunteer in school Consumer 3.Lab. capacity 4.Develop food test kit 3 In 2008, Law to establish National Committee on has been issued. (National Committee on Act 2551) To coordinate the activities: 1. quality 2. safety 3. security 4. education Chair by the prime minister safety based on risk analysis 4 Generic components of risk analysis Risk Communication Risk Analysis Activity Risk Risk Management Scientific inputs Decisions involving Policy and values Interactive and ongoing exchange of information and opinions

2 Benefits for national governments of using food safety risk analysis Risk Analysis allows likely costs of implementation and compliance to be compared with expected benefits. Supports setting research priorities of food safety problems. Supports food safety regulators for effective decision-making for food safety management chemical risk assessment 2007 Thai FDA 2011 Thai FDA exposure 3- MCPD Seasoning sauce sulfure dioxide ochratoxin cadmium acrylamide Sodium benzoate Ready to eat food packed in plastic bag 7 8 microbiological risk assessment 2002 ACFS Exposure V. parahaemolyticus Shrimp Salmonella Chicken C. jejuni Chicken V. parahaemolyticus Crab meat 2005 ACFS Exposure Consumption 2006 ACFS L. monocytogenes Chicken Staph. aureus Nham Muu 2008 V. parahaemolyticus Shrimp Salmonella Vegetable 2009 Hazard Salmonella + Characterization V. parahaemolyticus 2010 Thai FDA B. cereus Milk powder microbiology risk assessment 2002 ACFS Exposure V. parahaemolyticus Shrimp Salmonella Chicken C. jejuni Chicken V. parahaemolyticus Crab meat 2005 ACFS Exposure Consumption 2006 ACFS L. monocytogenes Chicken Staph. aureus Nham Muu 2008 V. parahaemolyticus Shrimp Salmonella Vegetable 2009 Hazard Characterization Salmonella + V. parahaemolyticus 2010 Thai FDA B. cereus Milk powder 9 [Text] Activity : Identification of the responsible organization for risk assessment, risk management, and risk communication Draw risk assessment road map and frame work Expert list Priority areas [ Text] Capacity building Risk Analysis Agencies Thai FDA ACFS DMSc Organization Institute of Nutrition Knowledge Network Institute of Thailand Some Universities FSOC Role Risk manager, Risk communicator Risk manager, Risk communicator Risk communicator Abbreviation : FDA = and Drug Administration, ACFS = National Bureau of Agricultural Commodity and Standards, DMSc = Department of Medical Sciences, FSOC = Safety Operation Center

3 Microbiology Chemical GMOs 2011 : Committee on Risk for Safety of Thailand Toxicity of 3-MCPD A long-term study indicates that Carcinogenicity of rat s kidney relates to the quantity of exposure to 3-MCPD. However, 3-MCPD is not a genotoxic substance. The 3-MCPD regulatory levels Organizations/Countries Scientific Committee on (SCF) < 10 ppb EU < 20 ppb Advisory Committee (FAC) < 10 ppb USA < 1 ppm (only acid-hvp) Canada < 1 ppm Australia and New Zealand < 20 ppb Malaysia < 20 ppb Codex and Japan Objectives Areas of Study To obtain the risk assessment data for CODEX and Thai FDA decision on the maximum level to be set as standard d To improve and develop the efficiency of analysts in risk assessment on-the-job training) Hazard Identification Dose-response assessment Exposure Risk Characterization 3

4 Hazard Identification Dose-response assessment Study the properties of 3-MCPD Study its toxicological properties and estimate its abilities to cause toxicity in human Study relations between quantity of 3-MCPD and its effect on experimental animals and human Study the process that cause an effect to experimental animals and human Exposure Risk Characterization 1. Conduct a survey of food consumption data 2. Conduct a survey of contamination of 3-MCPD in food 3. Estimate the amount of 3-MCPD that can be exposed by human Collect the results from exposure assessment and from estimated responding at the different quantities to estimate the risk from toxicity as well as to indicate the uncertainty Exposure assessment result 1. General Information of households ( 512 households, 1,945 persons) in four regions Areas City (person) Countryside (person) Central North Northeast South Total , Total % , consumption survey Household food disappearance method Frequency questionares

5 Result Exposure Thai people expose to 3-MCPD from food consumed everyday at g/kg g bw/day in average Conclusion The amount of 3-MCPD that Thai people expose to is in safety level. Risk Characterization The exposure amount equals to 1.8% of PMTDI assigned by JECFA (2 g/kg bw/day)

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