In the name of Allah The most gracious The most merciful
|
|
|
- Wesley Young
- 6 years ago
- Views:
Transcription
1 In the name of Allah The most gracious The most merciful
2 By Dr.Nancy Abd El Fattah Assistant prof. of internal medicine
3 3-6 m in length 300m2 in surface area Upper 40% duodenum & Jejunum Folds villi micro villi
4 Enteric nervous system : 10 8 neurons Controls the functioning of the small intestine Autonomous Coordinate with C.N.S
5 Gut motility interstitial cells of Cajal. MMC I. Quiescence period II. irregular contractile activity III. regular phasic contractions
6 Neuroendocrine peptide production : APUD cells hormones Complex action Interact with each other & with ENS
7
8 General principles of absorption simple diffusion facilitated diffusion active transport
9 Absorption of nutrients in the small intestine (1) Carbohydrates amylase - starch monosaccharide (2) protein: trypsin - dietary protein a.a. & peptides (3) fat Bile & P.lipase - TGDcholesterol F.A. & M.G. fat soluble V. medium MCT portal Vein
10
11 Water & electrolytes Dietary & intestinal secretions absorbed coupled with absorption of monos. a.a. & bicarbonate in jejunum also ileum & colon
12 water soluble vitamins metals & trace elements calcium absorption Iron absorption
13 Response of small bowel to antigens & pathogens physical defence mucus layer shedding of surface epithelial like cells movement of luminal contents colonization resistance
14 chemical defence Enzymes = lysozymes Antimicrobial peptides : defensins Trefoil peptides : 3 factors, promotion of repair
15 Immunological defence Humoral : Ig A B cell sensitization B cell turn into plasma cell Mesenteric L.N. TD blood small bowel LP Cellular defence T lymphocytes : GALT peyer CD4 lamina propria CD8 Intraepithelial
16 Commensal bacteria hundred thousand billion microbes activated immune system driven by the flora chemical signals recognized by toll like receptors that repair the epithelium.
17 Oral tolerance barrier function to prevent excess Ag uptake active inhibition by T cells & dendritic cells excessive responce to gluten Coeliac
18
19 presenting features of small bowel disease : 10 20% no symptoms! diarrhoea streatorrhoea abdominal pain weight loss Nutritional deficiencies
20
21 Investigation of small bowel disease
22 Tests of absorption fat malabsorption lactose tolerance test hydrogen breath test tests for pancreatic insufficiency other blood tests tests for PLE antitrypsin clearance Bile salt loss Stool tests
23
24
25 Inflammation of mucosa of upper small bowel 1% population Prolamins gliadin wheat hordeins barley secalins rye
26 Resist digestion & remain in the intestine triggering immune response Bind to APC HLAII CD 4 T interferon gamma B cell endomysial & tissue glutaminase a.b. villous atrophy mainly proximal small bowel
27 10 15% of 1st degree relative 90% of pts has HLADQ2 C/P any age more silent or? IBS routine ex MCV or Fe tiredness, malaise & anaemia neuropsychiatric : anxiety or depression osteoporosis
28 Diagnosis small bowel biopsy (2nd part) endoscopy subtotal villous atrophy endomysial & anti tissue glutaminase a.b. 90% sensitivity HLA DQ2 in 90% Ca, Fe &folate P Albumin & Hb Howell Jolly bodies S.B. follow through Dilatation DXA Capsule endoscopy
29 ttt Replace iron folic acid, Ca, vits, gluten free diet for life Oats are tolerated Meat dairy products & fruits are all safe EMA, t TG for monitoring pneumococcal vaccine every 5 ys
30 Complications refractory C.D. enteropathy associated Tcell lymphoma small bowel adenocarcinoma ulcerative jejunitis carcinoma of the oesophagus
31 uncommon blistening subepidermal eruption of the skin associated with gluten sensitive enteropathy morph.abn. not as severe as in C.D. skin condition responds to dapsone gluten free diet improves both enteropathy & skin lesion
32 chronic diarrhoea in residents or visitors of tropical areas T.sprue : severe malabs T. malabsorption : mild asymptomatic Aet : unknown? infective
33 Clinical features : Diarrhoea, anorexia abd. distension & wt loss (of variable intensity ) Epidemics thousands
34 Diagnosis &ttt Acute infective causes must be excluded esp. giardia Partial villous atrophy Leave the sprue area + f. A, 5 mg/d tetracycline lg daily /6m B12 in acute cases
35 Anaerobic bacteria more than aerobic Ileum & colon mainly major functions : ferment non digestible residue vit K production protect gut mucosa of colonization B.O. found in structural abnormality as stricture or div. Elderly It deconj. B. salts so can be found in small bowel aspirates
36 C/P & ttt diarrhoea & steatorrhoea steatorrhoea dto conj. Bile salt deficiency B12 serum folate Diagnosis : hydrogen breath test ttt : correct underlying lesion Metronidazole, teracycline or ciprofloxacin
37
38 If massive leaving < 1m.of small intestine J.R. better tolerated than I.R. Ileal resection : Bile salt induced diarrhoea. Steatorrhoea and gallstone formation. Oxaluria & oxalate stones. B12 deficiency Diagnosis: SBFT, SeHCAT, B12 ttt : B12 & Cholestyramine.
39 Jejunal resection: Ileum compensate for absorption. Gastrin hypersecretion.
40 Massive intestinal resection (Short bowel syndrome) (1) Shortened S.I ending at a terminal S.B. stoma : sodium & fluid depletion. ttt : Octreotide, PPI, loperamide cholestyramine & Bile acids. (2) Shortend S.I continuity with colon: ttt: low fat high CHO diet.
41 Rare bact. Dse, Tropheryma whipplei 1000 cases 87% male, Arthritis, wt loss, diarrhoea Fever, heart, lung, joint & Brain. Endoscope: Pale shaggy duod mucosa ẻ eroded red friable patches. Diagnosis ttt Trilaminar cell wall of T. whipplei inside macrophages PCR & T. antibodies. 2wks streptomycin & penicillin or ceftriaxone then cotrimoxazole dialy for a year
42 > 40 Gy will damage the intestine fibrotic stricture ischaemia & obstruction ms atrophy & ulcerative changes Nausea, vomiting, diarrhea that improve in 6wks If > 3m. chronic radiation enteritis Malabs. dto bact. over growth ttt Symptomatic Surgery only if obst. or perf. Local steroids for proctitis.
43 Giardia Cryptosporidiosis HIV patients.
44 Bile salt binders & some antibiotics Orlistat ( lipase) Thyrotoxicosis. Zollinger Ellison S. Int.lymphangiectasia. Lymphoma. D.M. Hypogammaglobulinaemia.
45
Malabsorption: etiology, pathogenesis and evaluation
Malabsorption: etiology, pathogenesis and evaluation Peter HR Green NORMAL ABSORPTION Coordination of gastric, small intestinal, pancreatic and biliary function Multiple mechanisms Fat protein carbohydrate
Refractory celiac disease (RCD) KASSEM BARADA LEBANESE SOCIETY OF GASTROENTEROLOGY NOVEMBER, 2014
Refractory celiac disease (RCD) KASSEM BARADA LEBANESE SOCIETY OF GASTROENTEROLOGY NOVEMBER, 2014 Case scenario (1) A 49 year woman presents with intermittent watery diarrhea and bloating of two years
Digestion and Absorption
Digestion and Absorption Digestion and Absorption Digestion is a process essential for the conversion of food into a small and simple form. Mechanical digestion by mastication and swallowing Chemical digestion
Malabsorption is characterized by defective absorption of: Fats fat- and water-soluble vitamins Proteins Carbohydrates Electrolytes Minerals water
Malabsorption Malabsorption is characterized by defective absorption of: Fats fat- and water-soluble vitamins Proteins Carbohydrates Electrolytes Minerals water presents most commonly as chronic diarrhea
NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE SCOPE. Coeliac disease: recognition, assessment and management of coeliac disease
Appendix B: NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE 1 Guideline title SCOPE Coeliac disease: recognition, assessment and management of coeliac disease 1.1 Short title Coeliac disease 2 The remit
Coeliac Disease Bible Class Questions and Answers
Coeliac Disease Bible Class Questions and Answers Jan Hendrik Niess What is the definition of coeliac disease? Coeliac disease is an immune reaction to gluten (wheat, barely, rye) in an genetic predisposed
Lower Gastrointestinal Tract KNH 406
Lower Gastrointestinal Tract KNH 406 Lower GI Tract A&P Small Intestine Anatomy Duodenum, jejunum, ileum Maximum surface area for digestion and absorption Specialized enterocytes from stem cells of crypts
Celiac Disease. M. Nedim Ince, MD University of Iowa Hospital
Celiac Disease M. Nedim Ince, MD University of Iowa Hospital Contents Cases Definition Etiopathogenesis Pathology Diagnosis Management of the disease Management of complications Case I Five year old boy
Kristin Kenrick, FRNZCGP Department of General Practice and Rural Health Dunedin School of Medicine (Supported by Coeliac New Zealand)
Kristin Kenrick, FRNZCGP Department of General Practice and Rural Health Dunedin School of Medicine (Supported by Coeliac New Zealand) That you will go away thinking about your practice population, and
Chapter 20 The Digestive System Exam Study Questions
Chapter 20 The Digestive System Exam Study Questions 20.1 Overview of GI Processes 1. Describe the functions of digestive system. 2. List and define the four GI Processes: 20.2 Functional Anatomy of the
BPK 312 Nutrition for Fitness & Sport. Lecture 2. Digestion & Absorption of Food Nutrients
BPK 312 Nutrition for Fitness & Sport Lecture 2 Digestion & Absorption of Food Nutrients 1. Overview of digestion & absorption of nutrients 2. Functional anatomy of the gastrointestinal (GI) tract 3. Digestion
Chapter 20 The Digestive System Exam Study Questions
Chapter 20 The Digestive System Exam Study Questions 20.1 Overview of GI Processes 1. Describe the functions of digestive system. 2. List and define the four GI Processes: 20.2 Functional Anatomy of the
Done By : shady soghayr
Done By : shady soghayr Malabsorption Malabsorption is characterized by defective absorption of: Fats fat- and water-soluble vitamins Proteins Carbohydrates Electrolytes Minerals Water presents most commonly
Dr Kristin Kenrick. Senior Lecturer Dunedin School of Medicine
Dr Kristin Kenrick Senior Lecturer Dunedin School of Medicine Kristin Kenrick, FRNZCGP Department of General Practice and Rural Health Dunedin School of Medicine (Supported by Coeliac New Zealand) Because
Biomarkers of GI tract diseases. By Dr. Gouse Mohiddin Shaik
By Dr. Gouse Mohiddin Shaik Introduction The gastrointestinal (GI) tract is a complex system performing multiple biological functions which are anatomically distributed Site for food processing and absorption
SIBO
SIBO What is it? Small Intestinal Bowel Overgrowth A chronic bacterial infection of the small intestine Caused by bad bacteria such as E Coli and Clostridium migrating to the small intestine There is not
Digestive System 2. Lecture 12. Pathology and Clinical Science 1 (BIOC211) Department of Bioscience. endeavour.edu.au
Digestive System 2 Lecture 12 Pathology and Clinical Science 1 (BIOC211) Department of Bioscience Text Reference: Grossman, S.C. & Porth, C.M. (2014). Porth s Pathophysiology: concepts of altered health
Chronic diarrhea. Dr.Nasser E.Daryani Professor of Tehran Medical University
1 Chronic diarrhea Dr.Nasser E.Daryani Professor of Tehran Medical University Timing Acute diarrhea: 4 weeks Definitions Derived from Greek
Ingestion Digestion- Absorption- Elimination
DIGESTIVE SYSTEM 1 FUNCTIONS Organization GI tract==mouth anus Accessory organs Salivary glands, liver, pancreas, gallbladder Major Functions: Ingestion-mouth, teeth, tongue Digestion- chemical and mechanical
Tips for Managing Celiac Disease. Robert Berger MD FRCPC Gastroenterology New Brunswick Internal Medicine Update April 22, 2016
Tips for Managing Celiac Disease Robert Berger MD FRCPC Gastroenterology New Brunswick Internal Medicine Update April 22, 2016 Disclosures None relevant to this presentation Objectives Briefly review the
Level 2. Non Responsive Celiac Disease KEY POINTS:
Level 2 Non Responsive Celiac Disease KEY POINTS: Celiac Disease (CD) is an autoimmune condition triggered by ingestion of gluten leading to intestinal damage and a variety of clinical manifestations.
Coeliac Disease: Diagnosis and clinical features
Coeliac Disease: Diagnosis and clinical features Australasian Gastrointestinal Pathology Society AGM 28 Oct 2016 Dr. Hooi Ee Gastroenterologist, Sir Charles Gairdner Hospital Coeliac disease Greek: koiliakos
Soft palate elevates, closing off the nasopharynx. Hard palate Tongue Bolus Epiglottis. Glottis Larynx moves up and forward.
The Cephalic Phase Chemical and mechanical digestion begins in the mouth Saliva is an exocrine secretion Salivary secretion is under autonomic control Softens and lubricates food Chemical digestion: salivary
Gastrointestinal Anatomy and Physiology. Bio 219 Napa Valley College Dr. Adam Ross
Gastrointestinal Anatomy and Physiology Bio 219 Napa Valley College Dr. Adam Ross Functions of digestive system Digestion Breakdown of food (chemically) using enzymes, acid, and water Absorption Nutrients,
Chapter 26 The Digestive System
Chapter 26 The Digestive System Digestive System Gastroenterology is the study of the stomach and intestine. Digestion Catabolism Absorption Anabolism The actions of the digestive system are controlled
Series Editors: Daniel Kamin, MD and Christine Waasdorp Hurtado, MD
NASPGHAN Physiology Lecture Series GI Physiology Module: Absorption of Water and Ions Jason Soden, MD Reviewers: George Fuchs MD: UAMS College of Medicine / Arkansas Children s Hospital Wayne Lencer MD:
Short Bowel Syndrome: Medical management
Short Bowel Syndrome: Medical management La Sindrome dell'intestino Corto in età pediatrica Brescia 18 marzo 2011 Jon A.Vanderhoof, M.D. Division of Pediatric GI Harvard Medical School Children s Hospital,
Guidelines NICE, not NICE and the Daily Mail. Dr Andy Poullis Consultant Gastroenterologist
Guidelines NICE, not NICE and the Daily Mail 2018 Dr Andy Poullis Consultant Gastroenterologist Coeliac IBS Gall bladder polyps PEI PPI Who to test for Coeliac persistent unexplained abdominal or gastrointestinal
Digestive System. Part 3
Digestive System Part 3 Digestion Ingested materials must be broken down for absorption Majority of absorption in small intestine Water and alcohol in stomach mucosa Some salts and vitamins in large intestine
CIE Biology GCSE 7: Human nutrition
CIE Biology GCSE 7: Human nutrition Notes Humans need many different nutrients to survive. To receive these nutrients in the correct quantities, a balanced diet must be eaten. A balanced diet includes
NOTES: The Digestive System (Ch 14, part 2)
NOTES: The Digestive System (Ch 14, part 2) PANCREAS Structure of the pancreas: The pancreas produces PANCREATIC JUICE that is then secreted into a pancreatic duct. The PANCREATIC DUCT leads to the The
LECTURE 12: MUCOSAL IMMUNITY GUT STRUCTURE
LECTURE 12: MUCOSAL IMMUNITY GUT STRUCTURE - Small intestine in humans is around 3-4 metres long - Internal surface of the small intestines are lined by villi o Villi are composed of absorptive cells (epithelial/enterocytes)
Coeliac Disease: Symptoms, Diagnosis, Treatment and Management
Coeliac Disease: Symptoms, Diagnosis, Treatment and Management Dr Matthew Kurien Senior Clinical Lecturer and Honorary Consultant Gastroenterologist, University of Sheffield Benign Diseases Talk Outline
Digestive Lecture Test Questions Set 4
Digestive Lecture Test Questions Set 4 1. Which of the following is not associated directly with the small intestine: a. villi b. circular folds c. microvilli d. haustrae e. secretin 2. The largest (longest)
Monosaccharides: Little amounts Don t need any digestion
Slide 8 Digestion result in mono and disaccharides & alpha-dextrins (oligosaccharides) Alpha1-4 in sequences / alpha1-6 at branches Dietary carbohydrates: Polysaccharides: 1) Containing α(1,4)/ α(1,6)
Section Coordinator: Jerome W. Breslin, PhD, Assistant Professor of Physiology, MEB 7208, ,
IDP Biological Systems Gastrointestinal System Section Coordinator: Jerome W. Breslin, PhD, Assistant Professor of Physiology, MEB 7208, 504-568-2669, jbresl@lsuhsc.edu Overall Learning Objectives 1. Characterize
PATHOLOGY OF NON NEOPLASTIC LESIONS OF THE UPPER GASTROINTESTINAL TRACT.
PATHOLOGY OF NON NEOPLASTIC LESIONS OF THE UPPER GASTROINTESTINAL TRACT. OESOPHAGEAL LESIONS OESOPHAGITIS AND OTHER NON NEOPLASTIC DISORDERS Corrosive Gastroesophageal reflux (GERD), Pills, Acid intake,
RADIATION INDUCED SMALL BOWEL DISEASE. Dr Mnguni Supervisor: Dr Lohlun Radiation Oncology
RADIATION INDUCED SMALL BOWEL DISEASE Dr Mnguni Supervisor: Dr Lohlun Radiation Oncology INTRODUCTION Radiation therapy is not regularly indicated in the treatment of small bowel disease. Reasons are complex
Digestive System 7/15/2015. Outline Digestive System. Digestive System
Digestive System Biology 105 Lecture 18 Chapter 15 Outline Digestive System I. Functions II. Layers of the GI tract III. Major parts: mouth, pharynx, esophagus, stomach, small intestine, large intestine,
Non responsive coeliac disease: next steps for investigation. Dr Peter Mooney Clinical Research Fellow Royal Hallamshire Hospital, Sheffield, UK
Non responsive coeliac disease: next steps for investigation Dr Peter Mooney Clinical Research Fellow Royal Hallamshire Hospital, Sheffield, UK Outline Cases Non Responsive Coeliac Disease Causes Investigation
HDF Case Whipple s disease
HDF Case 952556 Whipple s disease 63 yo female complaining of a diarrhea for 2 months, weigth loss (12 Kg in 3 months), and joint pains. Duodenal biopsy performed. Scanning view, enlarged intestinal villi,
Digestion and Absorption
Digestion and Absorption General Considerations - No absorption in esophagus, little in the stomach and vast majority of absorption occurs in small intestine. - The small intestine has specialized structures
The Digestive System. What is the advantage of a one-way gut? If you swallow something, is it really inside you?
The Digestive System What is the advantage of a one-way gut?! If you swallow something, is it really inside you? Functions and Processes of the Digestive System: Move nutrients, water, electrolytes from
Chapter 9: Digestion Review Assignment
_ Date: Mark: /45 Chapter 9: Digestion Review Assignment 45 Multiple Choice = 45 Marks Identify the choice that best completes the statement or answers the question. 1. Which of the following roles do
Sphincters heartburn diaphragm The Stomach gastric glands pepsin, chyme The Small Intestine 1-Digestion Is Completed in the Small Intestine duodenum
Sphincters are muscles that encircle tubes and act as valves. The tubes close when the sphincters contract and they open when the sphincters relax. When food or saliva is swallowed, the sphincter relaxes
DIGESTION SBI 3C: NOVEMBER 2010
DIGESTION SBI 3C: NOVEMBER 2010 DIAGRAM OF DIGESTIVE SYSTEM: Mouth Esophagus Liver Gallbladder Large Intestine Appendix Stomach Pancreas Small Intestine Rectum Anus STAGES OF DIGESTION: 1. INGESTION Taking
Chapter 14: The Digestive System
Chapter 14: The Digestive System Digestive system consists of Muscular tube (digestive tract) alimentary canal Accessory organs teeth, tongue, glandular organs 6 essential activities 1. 2. 3. 4. 5. 6.
5. Which component of the duodenal contents entering the stomach causes the most severe changes to gastric mucosa:
Gastro-intestinal disorders 1. Which are the most common causes of chronic gastritis? 1. Toxic substances 2. Chronic stress 3. Alimentary factors 4. Endogenous noxious stimuli 5. Genetic factors 2. Chronic
SUMMARY Coeliac disease is a common food intolerance in Western populations, in which it has a prevalence of about 1%. In early infancy, when the transition is made to a gluten-containing diet (particularly
Understandings, Applications & Skills
D.2 Digestion Understandings, Applications & Skills Statement D.2.U1 Nervous and hormonal mechanisms control the secretion of digestive juices. D.2.U2 Exocrine glands secrete to the surface of the body
Ch 18. Physiology of the Digestive System
Ch 18 Physiology of the Digestive System SLOs List the functions of the digestive system Distinguish and describe the different patterns of motility observed in the GI tract. Name and explain the various
Tuesday 10 th April 2018 Dr Rukhsana Hussain. Disclaimers apply:
Tuesday 10 th April 2018 Dr Rukhsana Hussain What is Non-Coeliac Gluten Sensitivity (NCGS)? Symptoms Pathophysiology Diagnosis Treatment Summary NCGS is a condition in which consumption of gluten leads
Diagnosis of chronic Pancreatitis. Christoph Beglinger, University Hospital Basel, Switzerland
Diagnosis of chronic Pancreatitis Christoph Beglinger, University Hospital Basel, Switzerland Pancreatitis Pancreas Pancreas - an organ that makes bicarbonate to neutralize gastric acid, enzymes to digest
Laboratory assessment of nutritional status in children
Laboratory assessment of nutritional status in children Dr O Kiabilua Block 10 Chemical Pathology department University of Pretoria Malnutrition CHO, proteins, lipids,vitamins, mineral and trace elements
2013 Pearson Education, Inc. THE DIGESTION PROCESS: PART II
THE DIGESTION PROCESS: PART II Digestion in the Small Intestine Chyme from stomach contains Partially digested carbohydrates and proteins Undigested fats 2-3 hours in small intestine (up to 6 if sluggish)
Chapter 15 Gastrointestinal System
Chapter 15 Gastrointestinal System Dr. LL Wang E-mail: wanglinlin@zju.edu.cn Rm 608, Block B, Research Building, School of Medicine, Zijingang Campus Pancreatic Secretion The exocrine cells in the pancreas
Diseases of the gastrointestinal system. H Awad Lecture 2: small intestine/ part 2 and appendix
Diseases of the gastrointestinal system H Awad Lecture 2: small intestine/ part 2 and appendix Malabsorption most important causes of malabsorption: Celiac disease tropical sprue Lactase deficiency Whipple
PHYSIOLOGY OF THE DIGESTIVE SYSTEM
Student Name CHAPTER 26 PHYSIOLOGY OF THE DIGESTIVE SYSTEM D igestion is the process of breaking down complex nutrients into simpler units suitable for absorption. It involves two major processes: mechanical
Digestion and Nutrition. Chapter 40
Digestion and Nutrition Chapter 40 Impacts, Issues Hormones and Hunger Fat cells secrete leptin, which reduces appetite; an empty stomach secretes ghrelin, which makes you hungry the goal is healthy nutrition
Small Bowel Obstruction after operation in a severely malnourished man. By: Ms Bounmark Phoumesy
Small Bowel Obstruction after operation in a severely malnourished man By: Ms Bounmark Phoumesy Normal length of GI tract Normal length(achieved by age 9) Small bowel 600cm (Men: 630 cm; Women: 592 cm)
Chapter 8: Digestion. Structure and Functions of Digestive Organs Macronutrients Digestive Enzymes
Chapter 8: Digestion Structure and Functions of Digestive Organs Macronutrients Digestive Enzymes What organisms need Digestion? Heterotrophs - rely on ingestion of organic molecules for production of
Small bowel diseases. Györgyi Műzes 2015/16-I. Semmelweis University, 2nd Dept. of Medicine
Small bowel diseases Györgyi Műzes 2015/16-I. Semmelweis University, 2nd Dept. of Medicine Celiac disease (revised definition!) a systemic autoimmune disorder Occurs in genetically susceptible individuals
PERSISTENT DIARRHOEA. IAP UG Teaching slides
PERSISTENT DIARRHOEA 1 DEFINITION Prolongation of acute diarrhoea / dysentery for more than 14 days Generally associated with weight loss. 2 PROTRACTED DIARRHOEA Prolongation of acute diarrhoea or dysentery
Overview of digestion
Key concepts in Digestion. Overview of digestion introduction to the GI system Prof. Barry Campbell Cellular & Molecular Physiology e-mail: bjcampbl@liv.ac.uk http://pcwww.liv.ac.uk/~bjcampbl DIGESTION
Small intestine. Small intestine
General features Tubular organ longest part; 5-6 m most of chemical digestion absorption of nutrients reabsorption of H2O occurs. Two structural features; maximize the lumenal surface area villi microvilli
L1, 2 : Biochemical Aspects of Digestion of Lipids, Proteins, and Carbohydrates
L1, 2 : Biochemical Aspects of Digestion of Lipids, Proteins, and Carbohydrates OBJECTIVES: Understand the process of digestion of dietary lipids, protein and carbohydrates including, the organs involved,
- Most nutrients are absorbed before reaching the ileum. - Colon is responsible for final removal of electrolytes and water.
University of Jordan Department of physiology and Biochemistry Gastro-Intestinal physiology, Medical, Pt III. ---------------------------------------------------------------------------- Academic year:
Overview of digestion or, gut reactions - to food
Key concepts in Digestion. Indigestion module Overview of digestion or, gut reactions - to food Prof. Barry Campbell Gastroenterology Cellular & Molecular Physiology e-mail: bjcampbl@liv.ac.uk http://pcwww.liv.ac.uk/~bjcampbl
THE DIGESTIVE SYSTEM
THE DIGESTIVE SYSTEM Composed of two parts: 1. 2. There are 4 main parts of digestion: 1. Ingestion: 2. Digestion: a. Mechanical Digestion: Example: b. Chemical Digestion: Example: 3. Absorption: 4. Egestion:
ADVANCED DIPLOMA IN PRINCIPLES OF NUTRITION
ADVANCED DIPLOMA IN PRINCIPLES OF NUTRITION BY AMANDA BRODERICK BSc ANutR BSC HONS Sports Biomedicine and Nutrition Course Educators: Thomas Woods, William Eames @ShawPhotoTom BY AMANDA BRODERICK LESSON:
Abdulrahman Alhanbali. Lojayn Salah. Mohammad Khatatbeh. 1 P a g e
7 Abdulrahman Alhanbali Lojayn Salah Mohammad Khatatbeh 1 P a g e In this lecture we will talk about digestion and absorption of food in the alimentary tract. But first of all we have some important points
Anatomy of the Intes.ne: Epithelium, Lympha.cs, Vessels and Nerves
Master Course Gastroenterology 2015 Anatomy of the Intes.ne: Epithelium, Lympha.cs, Vessels and Nerves Dr. Stephanie Ganal Department Klinische Forschung University of Bern stephanie.ganal@dkf.unibe.ch
IBD 101. Ronen Stein, MD Assistant Professor of Clinical Pediatrics Division of Gastroenterology, Hepatology, and Nutrition
IBD 101 Ronen Stein, MD Assistant Professor of Clinical Pediatrics Division of Gastroenterology, Hepatology, and Nutrition Objectives Identify factors involved in the development of inflammatory bowel
UNIT 2: From Food to Fuel: How the Human Body Utilizes Food
UNIT 2: From Food to Fuel: How the Human Body Utilizes Food Introduction to the Digestive System PART ONE Systems of the Body The Digestive System Also referred to as alimentary system, the gut, gastrointestinal
Digestive System. Why do we need to eat? Growth Maintenance (repair tissue) Energy
Digestive System Why do we need to eat? Growth Maintenance (repair tissue) Energy Nutrients Nutrient = chemical that must be obtained by an organism from it s environment in order to survive; nutrients
Histologic Follow-up of People With Celiac Disease on a Gluten-Free Diet Slow and Incomplete Recovery
Anatomic Pathology / HISTOLOGIC FOLLOW-UP OF PEOPLE WITH CELIAC DISEASE ON A GLUTEN-FREE DIET Histologic Follow-up of People With Celiac Disease on a Gluten-Free Diet Slow and Incomplete Recovery Peter
P A T I E N T H A N D B O O K
PATIENT HANDBOOK Heal Your Gut, Heal Your Body The gastrointestinal (GI) tract is one of the most sophisticated systems of the human body. We often think of the GI tract for its primary role in digesting
NICE guideline Published: 2 September 2015 nice.org.uk/guidance/ng20
Coeliac disease: recognition, assessment and management NICE guideline Published: 2 September 2015 nice.org.uk/guidance/ng20 NICE 2017. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-ofrights).
Crohn's Disease. What causes Crohn s disease? What are the symptoms?
Crohn's Disease Crohn s disease is an ongoing disorder that causes inflammation of the digestive tract, also referred to as the gastrointestinal (GI) tract. Crohn s disease can affect any area of the GI
IBD 101. Ronen Stein, MD Assistant Professor of Clinical Pediatrics Division of Gastroenterology, Hepatology, and Nutrition
IBD 101 Ronen Stein, MD Assistant Professor of Clinical Pediatrics Division of Gastroenterology, Hepatology, and Nutrition Objectives Identify factors involved in the development of inflammatory bowel
Adult coeliac disease
Postgrad. med. J. (August 1968) 44, 632-640. PATENTS with idiopathic steatorrhoea present in many different ways. The dominant feature of the clinical presentation in 100 patients is shown in Table 1.
Overview of digestion or, gut reactions - to food
1 Key concepts in Digestion. Indigestion module Overview of digestion or, gut reactions to food Prof. Barry Campbell Gastroenterology Cellular & Molecular Physiology email: bjcampbl@liv.ac.uk http://pcwww.liv.ac.uk/~bjcampbl
Mucosal Immunology Sophomore Dental and Optometry Microbiology Section I: Immunology. Robin Lorenz
Mucosal Immunology Sophomore Dental and Optometry Microbiology Section I: Immunology Robin Lorenz rlorenz@uab.edu Why do we Need to Understand How the Mucosal Immune System Works? The mucosa is the major
Necrotizing Enterocolitis: The Role of the Immune System
Necrotizing Enterocolitis: The Role of the Immune System Patricia Denning, M.D. Associate Professor in Pediatrics Division of Neonatology Emory University School of Medicine What is NEC? What is NEC? Necrotizing
COMPLETE DIGESTIVE STOOL ANALYSIS - Level 5
COMPLETE DIGESTIVE STOOL ANALYSIS - Level 5 MACROSCOPIC DESCRIPTION Stool Colour Brown Result Range Brown Markers Colour - Brown is the colour of normal stool. Other colours may indicate abnormal GIT conditions.
Esophageal Disorders. Gastrointestinal Diseases. Peptic Ulcer Disease. Wireless capsule endoscopy. Diseases of the Small Intestine 7/24/2010
Esophageal Disorders Gastrointestinal Diseases Fernando Vega, MD HIHIM 409 Dysphagia Difficulty Swallowing and passing food from mouth via the esophagus Diagnostic aids: Endoscopy, Barium x ray, Cineradiology,
Holistic Healing Professional Practitioner Diploma Course Sample Pages Page 1
The last phase is called the intestinal phase and takes place about four hours after the gastric phase. The chyme passes through the small intestine, or duodenum, through the pyloric sphincter. This is
SHORT GUT SYNDROME (SGS) : A MANAGEMENT CHALLENGE!
SHORT GUT SYNDROME (SGS) : A MANAGEMENT CHALLENGE! Muhammad Saaiq DEPARTMENT OF SURGERY,PIMS, ISLAMABAD. Surgical Grand Round, Pakistan Institute of Medical Sciences (PIMS), Islamabad. September 23, 2005.
The Digestive System. Basic process of digestion. Mouth and Teeth 10/30/2016
The Digestive System Basic process of digestion 1. Ingestion: animal eats food. 2. Digestion: animal body breaks food down. Mechanical digestion: chewing (mastication). Chemical digestion: enzymes and
DIGESTIVE. CHAPTER 17 Lecture: Part 1 Part 2 BIO 212: ANATOMY & PHYSIOLOGY II
BIO 212: ANATOMY & PHYSIOLOGY II CHAPTER 17 Lecture: DIGESTIVE Part 1 Part 2 Dr. Lawrence G. Altman www.lawrencegaltman.com Some illustrations are courtesy of McGraw-Hill. SMALL INTESTINE DUODENUM > JEJUNUM
The Role of Food in the Functional Gastrointestinal Disorders
The Role of Food in the Functional Gastrointestinal Disorders H. Vahedi, MD. Gastroentrologist Associate professor of medicine DDRI 92.4.27 vahedi@ams.ac.ir Disorder Sub-category A. Oesophageal disorders
Digestive Care Advisor Training #1. Digestion 101 & H.O.P.E.
Digestive Care Advisor Training #1 & H.O.P.E. The Digestive System in Brief The Process of Digestion The human digestive system is a complex series of organs and glands that process food and excrete waste.
Nutritional Requirements in Intestinal Failure
Nutritional Requirements in Intestinal Failure Christopher Duggan, MD, MPH Center for Nutrition Center for Advanced Intestinal Rehabilitation (CAIR) Division of Gastroenterology, Hepatology and Nutrition
Digestive System. Part A Multiple Choice. 1. Which of the following is NOT a digestive enzyme? A. Pepsin. B. Ptyalin. C. Gastrin. D. Trypsin.
Digestive System Part A Multiple Choice 1. Which of the following is NOT a digestive enzyme? A. Pepsin. B. Ptyalin. C. Gastrin. D. Trypsin. 2. The presence of large numbers of mitochondria in the cells
Nutrients, Enzymes and Digestion Lesson 4: Digestion and Absorption. Digestive Tract and Accessory Organs
Nutrients, Enzymes and Digestion Lesson 4: Digestion and Absorption Digestive Tract and Accessory Organs http://highered.mheducation.com/sites/0072495855/student_view0/chapter26/animation organs_of_digestion.html
Objective 4- Digestion
Objective 4- Digestion 1. Describe why cells require nutrients Supply energy for metabolism (cell activities), matter for synthesis of new materials, cell reproduction, secretion and to regulate cell processes
The Wiltshire School of Beauty and Holistic Therapy
The Wiltshire School of Beauty and Holistic Therapy Certificate of Merit in Anatomy and Physiology W: www.wsbht.co.uk E: holistics@wsbht.co.uk T: 07824 337333 Certificate of Merit in Anatomy and Physiology
UNDERSTANDING THE DIGESTIVE SYSTEM
UNDERSTANDING THE DIGESTIVE SYSTEM Understanding Digestion The key to solving food and digestive issues starts with an understanding of how the digestive and intestinal system works If you know what is
University of Buea. Faculty of Health Sciences. Programme in Medicine
Faculty of Health Sciences University of Buea Wednesday, 28 th January 2009 Time: 8 00-10 00 Programme in Medicine MED 303 (Gastrointestinal Physiology) EXAMS (2008-2009) Identify the letter of the choice
Is a raised intraepithelial lymphocyte count with normal duodenal villous architecture clinically relevant?
424 ORIGINAL ARTICLE Is a raised intraepithelial lymphocyte count with normal duodenal villous architecture clinically relevant? S Mahadeva, J I Wyatt, P D Howdle... See end of article for authors affiliations...