Brain Balance. Restoring Damaged Neurotransmitter Connections. Melissa Warner

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1 Brain Balance Restoring Damaged Neurotransmitter Connections Melissa Warner

2 Meet Melissa

3 Brain Balance Restoring Damaged Neurotransmitter Connections Melissa Warner

4 Goals for Today: Review Success Rates of Nutrition + Recovery 1. How The Brain Functions 2. How Nutrition Impacts Brain Function 3. How to Balance Brain Biochemistry Using Nutrients to Maintain Recovery

5 Success Rates of Nutrition Program in Recovery Setting Published research shows that: Traditional recovery strategy 25% success If you combine strategy with a strong Nutrition Program, evidence suggests increase chance of recovery to 83.33%.

6 Success Rates of Nutrition Program in Recovery Setting Published research shows that: Traditional recovery strategy 25% success Research data suggests 20% substance abusers recovered with no treatment at all. If you combine strategy with a strong Nutrition Program, evidence suggests increase chance of recovery to 83.33%.

7 Nutrition Should Be Used in Combination with Recovery Treatment When brain chemistry is back to normal, the recovery of mind and spirit can much more readily take place. Balance your biochemistry at cellular level

8 Goals for Today: Review Success Rates of Nutrition + Recovery 1. How The Brain Functions 2. How Nutrition Impacts Brain Function 3. How to Balance Brain Biochemistry Using Nutrients to Maintain Recovery

9 How the Brain Works 2 percent of your body s weight Uses 20-30% of the calories you consume as energy to function

10 How the Brain Works The brain takes energy to transmit electrical signals through chemical molecules called neurotransmitters.

11 Neurotransmitters Most Affected By Addiction Serotonin Dopamine GABA Endorphins

12 Serotonin Mood Regulation

13 Serotonin Mood Regulation Balanced Serotonin: Positive Outlook Emotional Stability Self-Confidence Sense of Humor Ability relate to others Organize life Sleep Regulation Brain Relaxant During Addiction / Low Serotonin: Negativity, depression Worry, anxiety, low self esteem Panic attacks, Obsessive thoughts, Controlling, perfectionism Winter blues, SAD ADHD Irritability, Rage, Violent Sleep issues: Night-owl PMS, Estrogen Cycling

14 Serotonin Mood Regulation Substances that Fire Serotonin: Sweets Starch Tobacco Chocolate Ecstasy Marijuana Alcohol SSRI s: Prozac, Zoloft, Paxil Nutrients that Synthesize Serotonin: 5HTP Tryptophan

15 Dopamine The Spark

16 Dopamine The Spark Balanced Dopamine: Confidence, Ambition Motivation Focus, Ability solve problems Persistence, Determination Integrating information for creative solutions During Addiction / Low Dopamine: Apathetic depression Lack energy, drive Boredom Lack of focus ADD Cravings for stimulation from substances or thrills

17 Dopamine The Spark Substances that Fire Dopamine: Caffeine, Chocolate Sugar, Aspartame Prescription stimulants Cocaine, crack Methamphetamine Tobacco, Alcohol Opiates Diet pills Nutrients that Synthesize Dopamine: L-Tyrosine L-Phenylalanine DL-Phenylalanine Omega 3 s

18 Neurotransmitter - GABA

19 GABA The Calmer Balanced GABA: Calming, Grounding, Stabilizing Slow down & relax Resilient (stress) Restful sleep Organized, complete tasks Filter out distracting stimuli Muscle Relaxant During Addiction / Low GABA: Stressed, anxious, overwhelmed Stiff, tense, painful muscles Hard to relax Fatigued yet wired Overwhelmed, burned out Epilepsy, tremors Highly distractible

20 Substances that Fire GABA Substances that Fire GABA: Sugar Starches Alcohol Marijuana Tobacco Benzodiazepines Valium, Librium, Ativan, Xanax Nutrients that Synthesize GABA: GABA L-Theanine Glutamine True Calm

21 Neurotransmitter Endorphin Group

22 Endorphins Contentment Balanced Endorphin Production: Body s natural opioids Secretion leads to euphoric enjoyment Relieves pain, creates numbness Runner s High, bonding with baby, recalling happy memory During Addiction / Symptoms of Low Endorphins: Lack of pleasure Sensitive nature Chronic physical pain Chronic emotional pain Tearfulness Loneliness, grief

23 Endorphins Contentment Substances that Fire Endorphins: Sugar Opiates Food Alcohol Marijuana Heroine Self-harmful behaviors Nutrients that Synthesize Endorphins: Full amino-acid profile DL-Phenylalanine D-Phenylalanine Glutamine Glycine

24 Causes of Neurotransmitter Deficiency Poor Nutrition Maldigestion Malabsorption Environmental Pollution Pesticides Chemical Additives Recreation, Prescription, and OTC Drugs Physical and Emotional Stress

25 We re most fully alive, engaged, and productive when our brains have enough of the nutrients necessary to manufacture all of the neurotransmitters we need.

26 Goals for Today: Review Success Rates of Nutrition + Recovery 1. How The Brain Functions 2. How Nutrition Impacts Brain Function 3. How to Balance Brain Biochemistry Using Nutrients to Maintain Recovery

27 Nutrition and the Brain Uses 20-30% of the calories you consume A low-quality diet actually changes chemistry and functionality of your brain

28 Basal Metabolic Rate: Liver 27% Brain 20% Heart - 7% Kidneys 10% Skeletal Muscle 18% Other Organs 19%

29 DISTRIBUTION ENERGY goes first to: ENERGY goes last to:

30 DISTRIBUTION ENERGY goes first to: 7% 5-10% 37% ~35-40% ENERGY goes last to:

31 DURING ADDICTION DISTRIBUTION ENERGY goes first to: 7% 5-10% 15-20% 37% 50%+ <25% ~35-40% ENERGY goes last to:

32 Nutrient Therapy Hippocrates (( BC) Let Food Be Thy Medicine and Medicine Be Thy Food s work by Carl Pfeiffer, MD, PhD Pfeiffer s Law: For every drug that benefits a patient, there are natural substances that can achieve the same effect.

33 Epigenetics The study of how external factors influence gene expression. Epigenetic research confirms that the behavior of a person s genes doesn t depend on genes DNA sequence, but instead on external modifications to DNA through diet and lifestyle that turn genes on or off.

34 Epigenetics The study of how external factors influence gene expression.

35 Epigenetics Person A Person B Epigenetic Influences Epigenetic Influences -STRONG -VULNERABLE

36 Genetic Predisposition Means you re more genetically vulnerable to specific nutritional deficiencies and that your reactions when exposed to certain toxins are more severe than those of most other people

37 Neurotransmitter Synthesis Not given a lifetime supply at birth. The brain is a chemical factory that continuously produces neurotransmitter Primary raw materials for neurotransmitter synthesis are nutrients Amino acids, vitamins, minerals, and other natural biochemicals

38 Key to unlocking door to recovery is getting brain chemistry back to normal; and then recovery of mind and spirit can much more readily take place.

39 Goals for Today: Review Success Rates of Nutrition + Recovery 1. How The Brain Functions 2. How Nutrition Impacts Brain Function 3. How to Balance Brain Biochemistry Using Nutrients to Maintain Recovery

40 Nutrient Therapy Biochemically, the body identifies food in two forms: 1. Nutrient - Improve cellular function 2. Toxin - Impair cellular function

41 Nutrient Therapy #1. Eat nutrient-dense foods Full plate of real, plant-based food Well sourced meats Support cellular activity w/ lots of micronutrients B Vits aid synthesis of Serotonin, Dopamine, & GABA

42

43 #2. Avoid toxins Nutrient Therapy High fructose corn syrup, Trans Fats Artificial colors / flavors / sugars Pesticides, insecticides Clean 15 vs Dirty Dozen Drugs / Addictive Substances

44 Environmental Working Group

45 Nutrient Therapy #3. Maintain healthy blood sugar levels Eat EVERY 3-4 hours Protein and low-glycemic complex carbohydrates Healthy fats keep blood sugar in optimal range

46 How Hunger Causes Relapse A hungry brain goes off-line Less self-control Less impulse control Less access to sobriety skills Conditioned Response: Drug of Choice used to restore equilibrium

47 Specific Populations & Hypoglycemia Premenstrual Women Have more reactive blood sugar & need to eat more frequently. Smokers Most women relapse premenstrually Smoking causes a rapid rise in blood sugar with just as rapid a drop shortly after the cigarette is put out. Nicotine is the culprit. A smoker must totally stop in order to return their blood levels to normal and eliminate their symptoms.

48 Amino Acid Therapy

49 Amino Acid Therapy Analysis Take the assessment to see if you re experiencing symptoms of a specific Neurotransmitter Deficiency Use substances to suggestively diagnose Neurotransmitter Deficiency Find the Amino Acid Solution and begin supplementing

50 Why Amino Acid Therapy? Amino acids are raw materials for Neurotransmitter Synthesis Phenylalanine & Tyrosine; Pyridoxine (B6), Folic Acid (B9), Nicotinamide (B12) GABA Taurine & Glutamine; L-Theanine; Zinc, Pyridoxine(B6); GABA Tryptophan; Pyridoxine (B6)

51 Why Amino Acid Therapy? Extremely safe Effective Short onset to noticeable effects Empty stomach, 20 minutes Temporary Nutrient reserves built over time Oral amino acid therapy is cost effective and convenient Depending on how starved brain is, dose all day

52 Amino Acid Analysis X X X x

53 Amino Acid Therapy: Serotonin

54 Amino Acid Analysis X X x X X x X coffee

55 Amino Acid Therapy: Dopamine Omega 3 s

56 Amino Acid Analysis X X X X X coffee

57 Amino Acid Therapy: GABA

58 Endorphins Contentment Full amino complex DL-Phenylalanine D-Phenylalanine

59 Amino Acid Therapy: Hypoglycemia L-Glutamine Chromium

60 Nutrition Should Be Used in Combination with Recovery Treatment When brain chemistry is back to normal, the recovery of mind and spirit can much more readily take place. Balance your biochemistry at cellular level

61 Success Rates of Nutrition Program in Research shows that: Recovery Setting Traditional recovery strategy 25% success If you combine strategy with a strong Nutrition Program, evidence suggests increase chance of recovery to 83.33%.

62 References: Asprey, L, The Better Baby Book. How to Have A Healthier, Smarter, Happier Baby. Biochemistry. 5th edition. Section 30.2Each Organ Has a Unique Metabolic Profile. Bourre, JM, Effects of nutrients (in food) on the structure and function of the nervous system: update on dietary requirements for brain. Part 1: micronutrients. Bray, G, et al Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity. Am J Clin Nutr. Burgess JR, et al, Long-chain polyunsaturated fatty acids in children with attention-deficit hyperactivity disorder. Eliott, SS, et al Fructose, weight gain, and the insulin resistance syndrome1, 2, 3. Fagiolini, M et al., Epigenetic influences on brain development and plasticity. Neurobiology. Hathcock, J.N., Vitamin B6 (pyridoxine). In: Vitamin and Mineral safety 2nd edition. Hurley, Dan, Your Backup Brain. Psychology Today Javier A. Bravo, et al. Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. PNAS 2011 : v Ketchum, Katherine & Meuller, L. Ann: Eating Right to Live Sober Larson, Joan Mathews: Seven Weeks to Sobriety Lyte, M. Probiotics function mechanistically as delivery vehicles for neuroactive compounds: Microbial endocrinology in the design and use of probiotics. Joshi, K., et al, "Supplementation with flax oil and vitamin C improves the outcome of Attention Deficit Hyperactivity Disorder (ADHD). Kidd, PM A review of nutrients and botanials in the integrative management of cognitive dysfunction. Konikowska K, et al, "The influence of components of diet on the symptoms of ADHD in children. Improvement of neurobehavioral disorders in children supplemented with magnesium-vitamin B6. I. Attention deficit hyperactivity disorders Murrell A, et al, From genome to epigenome. Hum Mol Genet 14(Spec No 1):R3 R10 7 Purdue University Study Finds Link Between Fatty Acid Deficiency & Attention Deficit Hyperactivity Disorder (ADHD) Ross, Julia: The Mood Cure and The Diet Cure Schauss, Alexander: Diet, Crime and Delinquency Slagle, Pricilla, MD: The Way Up from Down Stitt, Barbara Reed: Food and Behavior, A Natural Connection Starobrat-Hermelin B, The effect of deficiency of selected bioelements on hyperactivity in children with certain specified mental disorders. Starobrat-Hermelin B, The effect of deficiency of selected bioelements on hyperactivity in children with certain specified mental disorder. Thiel R, Natural interventions for ADD and ADHD. Update of cell damage mechanisms in thiamine deficiency: focus on oxidative stress, excitotoxicity and inflammation Waddington CH. The epigenotype. Endeavour 1942;1: Walsh, WJ, Nutrient Power: Heal Your Biochemistry and Heal Your Brian.

63 What are you Feeding Your Brain?

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