Principles of ACL graft fixation. Ph. Landreau Aspetar Doha Qatar
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1 Principles of ACL graft fixation Ph. Landreau Aspetar Doha Qatar
2 Introduction The success of ACL surgery relies on patient selection, graft selection, fixation method, surgical technique (position, tensioning and surgical approach) and postoperative rehabilitation program. ACL graft fixation: major factor influencing the graft s mechanical properties in the immediate postoperative period. ==> Physiotherapy timing and protocol. Industry Numerous publications
3 ACL and Graft strength Noyes 1984 BTB = mean strength of 159 to 168 % of that of ACL. Estimation of the ACL in vivo loading during normal activity, on average, of 454 N.
4 Graft fixation Kurosaka 1987 Better mechanical properties on BPTB grafts fixed with interference screw than staples or sutures tied over buttons The fixation site is the weakest link of ACL reconstruction
5 ACL reconstruction decision 1. Graft choice Biomechanical Properties of Selected ACL Graft Tissues Tissue Ultimate tensile load N (% ACL) Stiffness (N/ mm) Cross-sectional area (mm2) Intact ACL 2160 (100%) BTB 10 mm 2977 (138%) Quadruple hamstring 4090 (189%) Quadriceps tendon 2352 (109%) West et al. 2. Fixation choice Fixation is the weakest link
6 Fixation Characteristics Strength: Load that causes permanent displacement of the graft fixation complex. Measured in newtons (N) Stiffness: Amount of strain or displacement produced by a given load. Measured in N/mm Slippage: Change in position of the initial graft fixation position at a specific number of submaximal load cycles
7 Strength: Activities of daily living and rehabilitation Minimum must be: 454 N (native ACL) Noyes FR, Butler DL, Grood ES, Zernicke RF, Hefzy MS. Biomechanical analysis of human ligament grafts used in knee-ligament repairs and reconstructions. J Bone Joint Surg Am. 1984; 66:
8 Characteristics of the fixation devices Jackson DW, Grood ES, Goldstein JD, et al: Acomparison of patellar tendon autograft and allograft used for anterior cruciate ligament reconstruction in the goat model. Am J Sports Med 1993;21: Kousa P, Jarvinen TL, Vihavainen M, Kannus P, Jarvinen M: The fixation strength of six hamstring tendon graft fixation devices in anterior cruciate ligament reconstruction: I. Femoral site. Am J Sports Med 2003;31: Kousa P, Jarvinen TL, Vihavainen M, Kannus P, Jarvinen M: The fixation strength of six hamstring tendon graft fixation devices in anterior cruciate ligament reconstruction: II. Tibial site. Am J Sports Med 2003;31: Exceed the 450-N safe early physiological loading threshold proposed by Noyes et al. West et al.
9 Stiffness and Slippage Stiffness: Aperture fixation (joint line) > nonaperture (at distant site) Ishibashi Y, Rudy TW, Livesay GA, Stone JD, Fu FH, Woo SL. The effect of anterior cruciate ligament graft fixation site at the tibia on knee stability:evaluation using a robotic testing system. Arthroscopy. 1997; 13: Scheffler SU, Sudkamp NP, Gockenjan A, Hoffmann RF, Weiler A. Biomechanical comparison of hamstring and patellar tendon graft anterior cruciate ligament reconstruction techniques: the impact of fixation level and fixation method under cyclic loading. Arthroscopy. 2002; 18: Slippage: 6 weeks of activities of daily living corresponds to approximately 220,000 cycles to the ACL. Grover DM, Howell SM, Hull ML. Early tension loss in an anterior cruciate ligament graft. A cadaver study of four tibial fixation devices. J Boint Joint Surg Am. 2005; 87:
10 Graft fixation must be: Strong enough to avoid failure. Stiff enough to restore load displacement response and allow biological incorporation of the graft into the bone tunnels. Secure enough to resist slippage under cyclic loading (during the first 1 to 2 months when conversion from mechanical to biologic fixation is occurring).
11 Efficiency of Graft Fixation: Multifactorial Characteristics of the fixation devices Site of fixation (aperture or nonaperture) Density of the bone Tibia or Femur Type of graft
12 Site of fixation / Graft / Tunnel Direct Indirect Aperture Non anatomical Semi-anatomical Anatomical Intratunnel Cortical Cancellous Cortical
13 Graft tunnel motion 2 types of motion, longitudinal graft motion (bungee effect) and sagittal graft motion (windshield wiper effect) Direct/non direct fixation to bone Level of fixation (aperture or nonaperture) Tunnel enlargement multifactorial Clatworthy MG, Annear P, Bulow JU, Bartlett RJ. Tunnel widening in anterior cruciate ligament reconstruction:a prospective evaluation of hamstring and patella tendon grafts. Knee Surg Sports Traumatol Arthrosc. 1999; 7:
14 Bone Mineral Density & Femur vs Tibia Bone dualenergy X-ray absorptiometry has shown that tibial metaphysis has a lower bone density compared to the femur. The force on the graft is in line with the tibial tunnel as opposed to the femoral tunnel. Fixation at the tibial interface is the weakest link in the graft construct system
15 BTB fixation: What you need to know. Bone plug healing: usually 6 weeks. Interference screw Transverse compression Transverse suspension Hybrid system: compression and suspension Press-fit
16 BTB interference screws Screw diameter: Comparison in both tibial and femoral of 7 and 9 mm screws with a gap size of 1 mm show superior fixation with the 9 mm screw on both sides. It was recommended that 7 mm screws should not be used on the tibial side. Kohn D, Rose C. Primary stability of interference screw fixation: influence of screw diameter and insertion torque. Am J Sports Med 1994;22:334-8.
17 BTB interference screws Screw length: No significance Brown CH Jr, Hecker AJ, Hipp JA, Myers ER, Hayes WC. The biomechanics of interference screw fixation of patellar tendon anterior cruciate ligament grafts. Am J Sports Med 1993;21: Black KP, Saunders MM, Stube KC, Moulton J, Jacobs CR. Effects of interference fit screw length on tibial tunnel fixation for anterior cruciate ligament reconstruction. Am J Sports Med 2000;28: No difference between screws which were 20 mm and 25 mm long. No significant difference in displacement, load to failure and stiffness (porcine ) between interference screws of length 12.5, 15 and 20 mm.
18 BTB interference screws Screw divergence: Fixation by the interference screw is maximal at angles up to 10. There is a significant reduction in tensile strength at angles over 20 (However, the mean pull-out strength remain at 497 N at 20 ). Divergence < 20 Ishibashi Y, Rudy TW, Livesay GA, et al. The effect of anterior cruciate ligament graft fixation site at the tibia on knee stability: evaluation using a robotic testing system. Arthroscopy 1997;13: Martin SD, Martin TL, Brown CH. Anterior cruciate ligament graft fixation. Orthop Clin North Am. 2002; 33:
19 BTB interference screws Bone mineral density: most important variable that influences initial fixation strength and stiffness and resistance to slippage during cyclic loading. Higher in femoral tunnel than tibial tunnel. > Larger screw diameter in tibial tunnel. > Anteromedial area of the tibia = most acceptable. A BMD of less than 0.6 g/cm2 had a mean ultimate load to failure below 500 N
20 BTB interference screws Metal or Bioabsorbable/ Biocomposite: no significant difference in fixation strength and outcome. Absorbable > Metal Less hardware Undistorted postoperative MRI Decreased graft laceration Easier revision surgery Absorbable < Metal Reported foreign-body reactions Potential for tunnel lysis Breakage or drive failure during insertion
21 BTB interference screws: Summary Relatively easy to use and inexpensive Provide aperture fixation Excellent stiffness Minimal slippage after cycling But potential screw laceration of either the bone plug suture or mostly the graft
22 Soft Tissue fixation: What you need to know. Soft tissue graft-bone integration: usually 6-12 weeks. Femur Compression Transfixion/Expansion Suspension Tibia Compression Expansion Cortical anchoring Hybrid fixation
23 Soft Tissue fixation: Interference screws Can be used on the tibia and the femur, and both bioabsorbable and metal screws show similar biomechanical properties in fixation of soft-tissue grafts Weiler A, Hoffmann RF, Stahelin AC, Bail HJ, Siepe CJ, Sudkamp NP. Hamstring tendon fixation using interference screws:a biomechanical study in calf tibial bone. Arthroscopy. 1998; 14:29-37 But lowest fixation strength, with significant slippage over time up to 5 mm Ahmad CS, Gardner TR, Groh M, Arnouk J, Levine WN. Mechanical properties of soft tissue femoral fixation devices for anterior cruciate ligament reconstruction. Am J Sports Med. 2004; 32:
24 Soft Tissue fixation: Interference screws Femur: Endopearl device Tibia: backup washers or staples Increasing the diameter to 1 mm more than the tunnel and length of the screw Compaction drilling (Selby et al.) Precise match of the tunnel to the graft diameter (0,5 mm) (Steenlage et al.)
25 Soft Tissue fixation: Interference screws Screw diameter: Bigger is better for fixation! Indeed, using screws smaller than tunnel diameter increases the risk of graft slippage, while larger screws might lead to graft damage. > Hybrid fixation: Suspension/screw Screw divergence: < 20
26 Soft Tissue fixation: Interference screws In contrast to bone plug fixation, metallic or bioabsorbable screws require greater lengths to adequately fix a soft tissue graft. On the tibial side, about 30 to 35 mm screws are recommended to achieve secure graft fixation. Bone mineral density.
27 Soft Tissue fixation: Alternative Femur Suspension Transfixion/Expansion Compression + Hybrid system
28 Soft Tissue fixation: Alternative Tibia Compression Expansion Cortical anchoring + Hybrid system
29 Conclusion The ACL fixation method chosen should consider: the immediate graft fixation strength and stiffness, according to the graft which is used, the surgeon s comfort, the appropriate rehabilitation program, the long-term clinical outcomes (potential future revision surgery).
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