The Hospital for Sick Children Technology Assessment at SickKids (TASK) FULL REPORT
|
|
- Marianna Caldwell
- 5 years ago
- Views:
Transcription
1 The Hospital for Sick Children Technology Assessment at SickKids (TASK) FULL REPORT WILL THE GROWTH SPURT CONTINUE? TRENDS IN CHILD HEALTH ECONOMIC EVALUATION: 1980 TO 2013 Authors: Shannon Sullivan, PhD Independent Consultant Wendy J. Ungar, MSc, PhD Child Health Evaluative Sciences, The Hospital for Sick Children Corresponding Author: Wendy J. Ungar, MSc, PhD The Hospital for Sick Children Peter Gilgan Centre for Research and Learning 11th floor, 686 Bay Street Toronto, ON, Canada M5G 0A4 tel: (416) , extension , fax: (416) , Report No Date: January 25, 2016 Available at:
2 ACKNOWLEDGEMENTS This research was supported with funding from The Hospital for Sick Children Research Institute. The following individuals are acknowledged with gratitude for their substantial contribution to the PEDE Project: Kate Tsiplova, Sarah Costa, Pooyeh Graili, Seija Kromm, Shayanthan Parameswaran, Richard Zur, Heather Burnett, and Elizabeth Uleryk. We thank Ms. Jeri Danyleyko and Christine Millan for administrative and technical support. CONFLICTS OF INTEREST The authors have no conflicts of interest to disclose.
3 TABLE OF CONTENTS ACKNOWLEDGEMENTS... ii LIST OF TABLES... iv LIST OF FIGURES... vi ABBREVIATIONS... vii 1 INTRODUCTION METHODS Data Source and Study Selection Search Strategy Data Collection Data Analysis RESULTS Volume of Publications Analytic Technique Journal Type Intervention Type Outcome Measures Age Group Disease category Target Population DISCUSSION Key Findings Comparison with Literature Strengths and Limitations Policy Implications and Future Research...40 REFERENCES...42 iii
4 LIST OF TABLES Table 1. Publications per 10-year period (n=2630)... 5 Table 2. Publications per 10-year interval by analytic technique (n=2630)... 7 Table 3. Publications in early ( ) and late ( ) periods by analytic technique (n=2630)... 7 Table 4. Publications in early ( ) and late ( ) periods by journal type (n=2630)... 9 Table 5. Publications by journal type and by analytic technique ( ) (n=2630 records) 10 Table 6. Publications in early ( ) and late ( ) periods by intervention type (n=2630)...11 Table 7. Publications by intervention type and by analytic technique ( ) (n=2630 records)...12 Table 8. Publications in early ( ) and late ( ) periods by outcome category (n=2630)...14 Table 9. Number of publications by outcome category and by analytic technique (n=2630 records)...15 Table 10. Publications in early ( ) and late ( ) periods by age category (n=2630 records*)...16 Table 11. Publications by intervention type and by age group (n=2630 records)...17 Table 12 Publications by summary outcome and by age group (n=2630 records)...19 Table 13. Publications in early ( ) and late ( ) periods by ICD9/10 disease category (n=2630)...21 Table 14. Publications by ICD-9/10 disease classification and by analytic technique (n=2630 records)...23 Table 15. Publications by ICD-9/10 disease classification and by intervention type (n=2630 records)...25 Table 16. Publications by ICD-9/10 disease classification and by age group (n=2630 records).29 Table 17. Publications by the ten most frequent target populations ( )...31 Table 18. Publications by the most frequent target populations ( )...32 Table 19. Publications by the ten most frequent target populations ( )...32 Table 20. Publications by the ten most frequent target populations ( )...33 Table 21. Publications by the ten most frequent target populations ( )...33 iv
5 Table 22. Most frequent target populations within infective and parasitic class ( ) (n=329 records)...34 Table 23. Most frequent target populations within pregnancy, childbirth and puerperium class ( ) (n=189 records)...34 Table 24. Most frequent target populations within certain conditions originating in the perinatal period ( ) (n=100 records)...35 Table 25. Most frequent target populations within congenital anomalies class ( ) (n=188 records)...35 Table 26. Most frequent target populations within health prevention ( ), (n=833 records)...36 Table 27. Most frequent target populations within health treatment ( ), (n=637 records)...36 Table 28. Most frequent target populations within detection ( ), (n=418 records)...36 v
6 LIST OF FIGURES Figure 1 Distribution of economic evaluations in PEDE by year ( )... 8 Figure 2. Analytic technique according to type of intervention studied...13 vi
7 ABBREVIATIONS PEDE CBA CEA CMA CUA HIV HPV ICD QALY QOL RSV WHO Pediatric Economic Database Evaluation cost benefit analysis cost-effectiveness analysis cost-minimization analysis cost-utility analysis human immunodeficiency virus human papilloma virus International Classification of Diseases quality adjusted life year quality of life respiratory syncytial virus World Health Organization vii
8 SUMMARY Introduction Economic evaluations conducted as part of health technology assessments in pediatric populations have unique features compared to those conducted in adults. The Pediatric Economic Database Evaluation (PEDE) project includes a comprehensive database of pediatric health economic evaluations published since The objective was to identify significant trends over time as well as methodological gaps to improve the quality of future studies and evidence for decision-making. Methods Medical and grey literature were searched for pediatric economic evaluations, key characteristics were extracted, frequencies were tabulated and selected cross-tabulations were performed. Differences in study characteristics between early (1980 and1999) and late (2000 and 2013) pediatric economic evaluations were assessed using a chi-squared statistic. Results A total of 2630 pediatric economic evaluations were published between 1980 and 2013 with an average annual growth rate of 15%. Substantially more cost-effectiveness analyses (CEAs) and cost utility analyses (CUAs) were published compared with cost benefit analyses (CBAs) and cost minimization analyses (CMAs) (64.5% and 24.0% versus 7.7% and 3.7%, respectively). This trend was consistent regardless of the type of intervention, disease or age group studied. A trend toward higher proportions of CUAs and CEAs was evident in the later period (X 2 p<0.0001). Other significant trends included more publications in health economics/policy journals and sub-specialty journals in the later period (X 2 p<0.0001), a higher proportion of studies of preventive interventions in the later period (X 2 p<0.0001), and more studies in children and fewer in perinates in the later period (X 2 p<0.0001). Overall the most common disease class studied was infectious diseases (29%). viii
9 Conclusions The field of pediatric economic evaluation continues to grow in volume and methodologic complexity. While CUAs have increased, the quality of CUAs remains unknown. Although most studies are in infectious disease, the volume of publications may not align with emerging child health priorities and target populations, such as adolescent health, injury, developmental disabilities, mental health, and the use of personalized medicine. Increasing economic evaluations in these areas will enhance pediatric decision-making. ix
10 1 INTRODUCTION Health economic evaluations provide a comparison of the costs and health consequences of various interventions in a specified population. Results of economic evaluations are used by health practitioners and decision makers to assist with both clinical treatment and health policy decisions(1, 2). However, economic evaluations conducted in pediatric populations have unique features and challenges when compared with those conducted in adults. This includes the impact of child growth and development on disease processes and intervention effectiveness; a reliance on care-giving adults such as parents and teachers to facilitate access to healthcare services and act as a proxy for reporting health outcomes; the inability to accurately measure preferences for health states for very young children and infants; and the importance of considering lost productivity of caregivers and over a child s lifetime(3-6). The Pediatric Economic Database Evaluation (PEDE) project was developed to identify methodological gaps in order to improve the quality of pediatric economic evaluations. PEDE is a publicly available, searchable, comprehensive database of pediatric economic evaluations published since 1980(7, 8). An initial analysis of pediatric economic evaluations in the database covering the period from 1980 to 1999 indicated that the annual volume of studies was growing but that cost utility analyses were infrequently conducted, suggesting the need for greater methodological developments in ascertaining child health utilities(9). Continuing to monitor trends in pediatric economic evaluations will highlight areas of recent growth in the field as well as identify areas for future methodological developments in pediatric health economics. This could help advance methodologies in child health economic evaluation and ultimately enhance pediatric healthcare decision-making. Although globally infectious diseases have been a key focus in pediatric populations (10), in recent years shifts in priorities in child health include a greater policy emphasis on chronic non-infectious diseases, mental health, and conditions resulting from prematurity of birth(11, 12). There has also been a recent growth in the fields of genetics and personalized medicine for primary and secondary prevention of conditions affecting children over their lifetime (13-15). Economic evaluations of emerging technologies are essential to inform budget allocation decision-making, but it remains unclear whether shifts in child health priorities are reflected in the pediatric health economic literature. 1
11 The objectives of this study are to report and evaluate trends in pediatric health economic evaluation over the period of 1980 to The analysis compared study characteristics between two periods: 1980 to 1999 (early period) and 2000 to 2013 (late period). 2
12 2 METHODS 2.1 Data Source and Study Selection The analysis was conducted using the PEDE database, a comprehensive database of all pediatric economic evaluations published since January 1, A publication is eligible to be included in PEDE if one or more comparators exists and descriptions of both costs and health outcomes are present. Eligible studies examined interventions directed at children of any age, or at pregnant or breastfeeding women as long as outcomes were measured in the offspring. The economic evaluation did not have to be the primary objective of the study to be eligible for the database. Detailed inclusion and exclusion criteria for determining eligibility are provided elsewhere (7). Because the database focuses on patient health outcomes rather than the structures and processes of health care, studies of interventions consisting of a guideline, a quality improvement process, or a new operating procedure or policy targeted toward improving practice or efficiency were excluded. Inter-rater reliability training is performed for all reviewers performing citation selection and data extraction to achieve a high level agreement (kappa values >0.9). 2.2 Search Strategy PEDE is updated annually using custom search strategies for retrieval of citations designed to achieve high sensitivity. Economic and medical literature citation databases routinely searched include MEDLINE, CINAHL, EMBASE, IPA, EconLit, the Cochrane Collection, NHS EED, DARE, HTA, and ERIC. Over 73 web sites of HTA agencies and research groups are also searched for inclusion of eligible grey literature. The full search strategy for each citation database is available on request. 2.3 Data Collection The database includes characteristics for each citation and is linked to a searchable bibliographic database containing the full citation information and abstract. Variables extracted for each citation include: year journal type (dentistry, general medicine, health economics/policy/methods, pediatrics/perinatal medicine, pharmacology, public health, sub-specialty medicine, other) target population (free-text) 3
13 disease classification (based on International Classification of Diseases (ICD)-9 Clinical Modification (CM) or ICD-10 schema) age group (perinate, neonate, infant, child, adolescent, adult) intervention(s) studied intervention category (dental, detection, diagnosis, educational, health care delivery, health program, health treatment, health prevention, surgical) health outcome(s) (free-text) analytical technique (CMA, CEA, CUA, CBA) For free-text variables, summary categories are used when possible and recorded in the database. On-line data entry is performed using REDCap, a secure, web-based application designed to support data capture for research studies (16), and data are managed using Microsoft Access (Redmond, WA) and EndNote (Philadelphia, PA). Additional details on the development of the database and variable definitions are provided elsewhere (7, 17). 2.4 Data Analysis Trends in the pediatric economic evaluations were explored by performing one-way frequency distributions and two-way cross-tabulations on variables within the database. Descriptive statistics were used to describe the key characteristics of publications including publication year, disease category, intervention type, outcome measures, age group and target population. Data analyses were performed using Microsoft Excel (Redmond, WA). The trend analysis considered two main periods: 1980 to 1999 (early period) and 2000 to 2013 (late period). Study characteristics were compared between periods using a chi-squared statistic. For the purposes of analysis, only the primary study outcome was considered. 4
14 3 RESULTS Trends over time and difference between early and late intervals are presented for volume of publications, analytic technique, journal type, intervention type, outcome measures, age group, disease category and target population. Select cross-tabulation by age group and by analytic technique are also presented. 3.1 Volume of Publications Between 1980 and 2013, a total of 2630 pediatric economic evaluations were published, with numbers steadily increasing over time (Table 1). Between 1980 and 1989, there were 154 studies published (5.9% of the total), rising to 655 (24.9%) between 1990 and 1999, and increasing again to 1335 (50.8%) between 2000 and Between the four-year period of 2010 and 2013, there were 486 publications (18.5%). The average annual increase in publication volume between 1980 and 2013 was 15.2%. Table 1. Publications per 10-year period (n=2630) Year n % % change % % 325.3% % 103.8% % -- TOTAL % 5
15 3.2 Analytic Technique Economic evaluations are often classified based on the analytic technique. The four main types are cost-effectiveness analysis (CEA), cost-utility analysis (CUA), cost-benefit analysis (CBA), or cost-minimization analysis (CMA). Of the 2,630 economic evaluations included in PEDE, 64.5% are CEAs, 24.0% are CUAs, 7.7% are CBAs, and 3.7% are CMAs. The distribution of the types of analyses have changed significantly over time (X 2 p<0.0001). Both CEAs and CUAs have increased over time while the CMAs and CBAs have decreased. This trend can be observed by looking at 10-year periods and when comparing early (1980 to 1999) versus late (2000 to 2013) periods (Table 2 and Table 3). More recently there has been a trend of decreasing CEAs between 2010 and 2013 compared with earlier decades. This decrease is CEAs was offset by an increase in CUAs during the same period (Figure 1). In 2009, CUA, the approach recommended by economic evaluation guidelines (1, 2), overtook CEA as the most common type of analytic technique for the first time. 6
16 Table 2. Publications per 10-year interval by analytic technique (n=2630) Analytic Technique TOTAL n col% row% n col% row% n col% row% n col% row% n % CBA % 19.2% % 37.9% % 36.5% % 6.4% % CEA % 5.9% % 29.8% % 53.0% % 11.3% % CMA % 11.2% % 42.9% % 43.9% 2 0.4% 2.0% % CUA 4 2.6% 0.6% % 4.9% % 50.3% % 44.1% % TOTAL % 5.9% % 24.9% % 50.8% % 18.5% % Abbreviations: CBA = cost benefit analysis; CEA = cost-effectiveness analysis; CMA = cost-minimization analysis; CUA = cost-utility analysis Table 3. Publications in early ( ) and late ( ) periods by analytic technique (n=2630) Analytic Technique Early ( ) Late ( ) TOTAL n col% row% n col% row% n % CBA % 57.1% % 42.9% % CEA % 35.7% % 64.3% % CMA % 54.1% % 45.9% % CUA % 5.5% % 94.5% % TOTAL % 30.8% % 69.2% % Abbreviations: CBA = cost benefit analysis; CEA = cost-effectiveness analysis; CMA = cost-minimization analysis; CUA = cost-utility analysis 7
17 Number of Economic Evaluations CBA CEA CMA CUA Year of Publication Figure 1 Distribution of economic evaluations in PEDE by year ( ) 3.3 Journal Type Economic evaluations may be published in a variety of journal types given the breadth of topics and analyses that are conducted. Of the eight journal categories (dentistry, general medicine, health economics/policy/methods, pediatrics/perinatal medicine, pharmacology, public health, sub-specialty medicine, other), pediatric economic evaluations were most frequently published in subspecialty medicine journals and pediatrics/perinatal medicine journals (35.3% and 26.2%, respectively). This trend was consistent across both early and late periods (Table 4). However, the overall distribution of the type of journal in which economic evaluations are published changed significantly over time (X 2 p<0.0001). In the late period compared with the early period, publications decreased in general medicine, pediatrics/perinatal medicine and public health journals and increased in health economics/policy/methods journals and sub-specialty medicine journals (Table 4). 8
18 Table 4. Publications in early ( ) and late ( ) periods by journal type (n=2630) Journal Type Early ( ) Late ( ) TOTAL n col% row% n col% row% n % Dentistry % 43.4% % 56.6% % General medicine % 42.5% % 57.5% % Health Economics/ policy/methods % 16.3% % 83.7% % Pediatrics/perinatal medicine % 37.7% % 62.3% % Pharmacology % 40.0% % 60.0% % Public health % 40.6% % 59.4% % Sub-specialty medicine % 22.5% % 77.5% % Other % 20.7% % 79.3% % TOTAL % 30.8% % 69.2% % When the analytic technique used in each of the journal types was considered (Table 5), it was observed that CEAs were most frequently published in subspecialty medicine and pediatric/perinatal journals (33.7% and 30.8%, respectively), while CUAs were most frequently published in subspecialty medicine and health economic methods/policy journals (39.6% and 18.5%, respectively). Across all journal types and periods, CEAs were the most frequently published analytic technique. 9
19 Table 5. Publications by journal type and by analytic technique ( ) (n=2630 records) Journal Type CBA CEA CMA CUA TOTAL n row% col% n row% col% n row% col% n row% col% n % Dentistry % 4.4% % 2.4% 2 3.8% 2.1% 2 3.8% 0.3% % General medicine % 11.3% % 11.2% 8 2.9% 8.2% % 8.2% % Health economics/ policy/ methods % 6.4% % 7.0% 9 3.5% 9.3% % 18.5% % Pediatrics/perinatal medicine % 22.2% % 30.8% % 27.8% % 15.2% % Pharmacology 2 3.9% 1.0% % 1.9% 1 2.0% 1.0% % 2.4% % Public health % 20.2% % 10.9% 5 1.6% 5.2% % 13.0% % Sub-specialty medicine % 32.0% % 33.7% % 44.3% % 39.6% % Other 5 8.5% 2.5% % 2.1% 2 3.4% 2.1% % 2.7% % TOTAL % 100.0% % 100.0% % 100.0% % 100.0% % Abbreviations: CBA = cost benefit analysis; CEA = cost-effectiveness analysis; CMA = cost-minimization analysis; CUA = cost-utility analysis 10
20 3.4 Intervention Type Economic evaluations may be conducted for a wide range of types of interventions. Of the nine categories of interventions considered in this analysis (dental, detection, diagnosis, educational, health care delivery, health program, health treatment, health prevention, surgical), economic evaluations were most frequently conducted for health prevention, health treatments and detection interventions (31.7%, 24.2% and 15.9%, respectively. This trend was observed in both early ( ) and late periods ( ) (Table 6). However, the overall distribution of the type of intervention on which economic evaluations are conducted changed significantly over time (X 2 p<0.0001). In the late period compared with the early period, an increase in the evaluation of health prevention interventions from 25.0% to 34.7% was observed, accompanied by small decreases ( 5%) that were distributed across the other interventions. Table 6. Publications in early ( ) and late ( ) periods by intervention type (n=2630) Intervention Category Early ( ) Late ( ) TOTAL n col% row% n col% row% n % Dental % 45.6% % 54.4% % Detection % 35.9% % 64.1% % Diagnosis % 32.5% % 67.5% % Educational % 19.0% % 81.0% % Health care delivery % 32.4% % 67.6% % Health program % 42.3% % 57.7% % Health treatment % 30.8% % 69.2% % Health prevention % 24.2% % 75.8% % Surgical % 33.8% % 66.2% % TOTAL % 30.8% % 69.2% % When the analytic technique used for each of the intervention types was considered (Table 7 and Figure 2), it was observed that CBAs were most frequently conducted for health prevention interventions (49.8%), CEAs were most frequently conducted for health treatment and health prevention interventions (25.5% and 24.2%, respectively), CUAs were most frequently conducted on health prevention interventions (50.5%) and CMAs were most frequently conducted for health treatment interventions (41.8%). Although CEAs were frequently used to analyze all intervention types, diagnostic and surgical interventions were predominantly studied using CEAs (81.8% and 80.5%, respectively). 11
21 Table 7. Publications by intervention type and by analytic technique ( ) (n=2630 records) Intervention Type CBA CEA CMA CUA TOTAL n row% col% n row% col% n row% col % n row% col% n % Dental % 4.9% % 3.1% 3 4.4% 3.1% 3 4.4% 0.5% % Detection % 26.1% % 17.0% 8 1.9% 8.2% % 10.8% % Diagnosis 3 3.9% 1.5% % 3.7% 2 2.6% 2.0% % 1.4% % Educational 5 6.3% 2.5% % 3.1% 2 2.5% 2.0% % 3.2% % Health care delivery 3 1.8% 1.5% % 7.7% % 14.3% % 3.6% % Health program % 8.9% % 9.4% % 13.3% % 3.6% % Health treatment % 4.9% % 25.5% % 41.8% % 24.4% % Health prevention % 49.8% % 24.2% 2 0.2% 2.0% % 50.5% % Surgical 0 0.0% 0.0% % 6.3% % 13.3% % 2.1% % TOTAL % 100.0% % 100.0% % 100.0% % 100.0% % Abbreviations: CBA = cost benefit analysis; CEA = cost-effectiveness analysis; CMA = cost-minimization analysis; CUA = cost-utility analysis 12
22 Axis Title 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% CUA CMA CEA CBA Figure 2. Analytic technique according to type of intervention studied 3.5 Outcome Measures A wide variety of outcomes (n=1280) were measured across the 2630 publications in PEDE. When considering the primary outcome in each publication, the most frequent types of outcomes were QALYs or similar units, cases of non-infectious disease/condition/abnormality, cases of infectious disease/condition/abnormality and life years (22.0%, 18.6%, 13.6% and 13.2%, respectively). When comparing the early ( ) and late periods ( ), an increase in the use of QALYs was observed over time (4.9% versus 29.5%) paralleling the increased frequency of CUA (Table 8). 13
23 Table 8. Publications in early ( ) and late ( ) periods by outcome category (n=2630) Outcome Category Early ( ) Late ( ) TOTAL n col% row% n col% row% n % Cases of complications/ % 44.9% % 55.1% % adverse events Cost 0 0.0% 0.0% % 100.0% % Cases of % 49.7% % 50.3% % cures/improvements/healing Cases of infectious % 42.9% % 57.1% % disease/condition/abnormality Cases of injury 9 1.1% 45.0% % 55.0% % Life years % 31.6% % 68.4% % Cases of non-infectious % 40.8% % 59.2% % disease/condition/abnormality Other 6 0.7% 24.0% % 85.0% % Changes in physiologic measure % 37.1% % 62.9% % Changes in % 25.9% % 74.1% % behavioural/psychosocial QALYs, or similar unit % 6.9% % 93.1% % Changes in quality of life 3 0.4% 14.3% % 85.7% % Surrogate health outcomes 5 0.6% 17.9% % 82.1% % Time outcomes* % 24.3% % 75.7% % Unspecified 0 0.0% 0.0% 6 0.3% 100.0% 6 0.2% Cases of vaccination % 41.9% % 58.1% % TOTAL % 30.8% % 68.7% % *This category refers to days in a state or days absent from a state, time to achieve an outcome or to recover When the outcome category was grouped by analytic technique (Table 9), as expected, the outcome most frequently reported for CUAs were QALYs or similar measures (88.0%). For CEAs, the most frequently reported outcome measures were cases of non-infectious disease/condition/abnormality and life-years (23.2% and 18.1%, respectively). For CBAs, the most frequently reported clinical outcomes were cases of infectious disease/condition/abnormality and cases of non-infectious disease/condition/abnormality (35.0% and 33.5%, respectively); these outcomes were then monetized as is the standard approach in a CBA. For CMAs, cases of cures/improvements/healing were most frequently reported (28.6%). 14
24 Table 9. Number of publications by outcome category and by analytic technique (n=2630 records) Outcome Category CBA CEA CMA CUA TOTAL n row% col% n row% col% n row% col% n row% col% n % Cases of complications/adverse 5 3.4% 2.5% % 7.5% % 14.3% 1 0.7% 0.2% % events Cost % 3.0% % 0.9% % 4.1% 1 3.8% 0.2% % Cases of cures/improvements 7 3.9% 3.4% % 8.5% % 28.6% 2 1.1% 0.3% % Cases of infectious % 35.0% % 15.4% 3 0.8% 3.1% % 3.5% % disease/condition/abnormality Cases of injury % 1.5% % 0.9% 1 5.0% 1.0% 0 0.0% 0.0% % Life Years % 5.4% % 18.1% 7 2.0% 7.1% % 3.5% % Cases of non-infectious % 33.5% % 23.2% % 14.3% % 2.4% % disease/condition/abnormality Other 2 5.0% 1.0% % 2.0% 3 7.5% 3.1% 1 2.5% 0.2% % Changes in physiologic measure 5 2.5% 2.5% % 10.8% % 11.2% 3 1.5% 0.5% % Changes in behavioral/ psychosocial % 6.9% % 3.6% 4 4.9% 4.1% 2 2.5% 0.3% % QALYs, or similar unit 4 0.7% 2.0% % 1.1% 0 0.0% 0.0% % 88.0% % Changes in QOL 0 0.0% 0.0% % 1.0% 0 0.0% 0.0% % 0.6% % Surrogate Health Outcomes 1 3.6% 0.5% % 1.4% % 3.1% 1 3.6% 0.2% % Time Outcomes 0 0.0% 0.0% % 4.1% 2 2.7% 2.0% 2 2.7% 0.3% % Unspecified % 1.0% % 0.1% % 2.0% 0 0.0% 0.0% 6 0.2% Cases of vaccination % 2.0% % 1.5% 2 6.5% 2.0% 0 0.0% 0.0% % TOTAL % 100.0% % 100.0% % % % Abbreviations: CBA = cost benefit analysis; CEA = cost-effectiveness analysis; CMA = cost-minimization analysis; CUA = cost-utility analysis 15
25 3.6 Age Group The pediatric population is a heterogeneous group that is often classified and studied according to standard age groups related to periods of maturation and development. These age groups are typically perinate (antenatal period), neonate (newborn to < 1 month), infant (1 month to < 1 year), child (> 1 year to 12 years), adolescent (13 to 18 years), and adult (19 and older). The inclusion of adults age groups occurred i) in studies where interventions were targeted at pregnant or breastfeeding women and where outcomes were measured in offspring, or ii) in studied with lifetime time horizons. The most frequently studied age group was the child at 40.6% of publications, which was consistent across both early ( ) and late periods ( ) (Table 10). However, the overall distribution of the age groups studied changed significantly over time (X 2 p<0.0001). In the late period compared with the early period, economic evaluations of children increased from 35.7% to 42.9% while they decreased in perinates from 13.1% to 5.1% with small fluctuations (<5%) observed in other age groups. Table 10. Publications in early ( ) and late ( ) periods by age category (n=2630 records) Age Early ( ) Late ( ) TOTAL n col% row% n col% row% n % Perinate % 54.9% % 45.1% % Neonate % 27.1% % 72.9% % Infant % 34.6% % 65.4% % Child % 28.2% % 71.8% % Adolescent % 31.8% % 68.2% % Adult % 44.2% % 55.8% % TOTAL % 32.1% % 67.9% % Each record may contain multiple age groups; a total of 3863 age groups were studied When the type of intervention studied was categorized by age group (Table 11), diagnostic interventions were most frequently evaluated in perinates (41.4%), health prevention and detection interventions were most frequently studied in neonates (29.3% and 26.9%), health prevention interventions were most frequently studied in infants (43.6%), health prevention and health treatment interventions were most frequently studied in both children (33.0 and 29.8%) and adolescents (26.9% and 29.15). For adults included in these publications, health prevention interventions were most frequently studied (48.1%). 16
26 Table 11. Publications by intervention type and by age group (n=2630 records) (A = Perinate, Neonate, Infant; B = Child, Adolescent, Adult, Total) A INTERVENTION Perinate (antenatal period) Neonate (newborn to < 1 month) Infant (1 month to < 1 year) n row% col% n row% col% n row% col% Dental 0 0.0% 0.0% 1 1.0% 0.2% 7 7.3% 1.0% Detection % 41.4% % 26.9% % 7.5% Diagnosis 5 3.9% 1.7% % 3.2% % 4.0% Educational 0 0.0% 0.0% 7 6.4% 1.1% % 1.9% Health Care Delivery % 8.1% % 8.2% % 7.6% Health Program % 10.8% % 11.1% % 7.9% Health Treatment % 12.9% % 16.5% % 20.1% Health Prevention % 24.1% % 29.3% % 43.6% Surgical 3 1.4% 1.0% % 3.2% % 6.3% TOTAL % 100.0% % 100.0% % 100.0% B Intervention Type Child (> 1 year to 12 years) Adolescent (13 to 18 years) Adult (19 and older) TOTAL n row% col% n row% col% n row% col% n % Dental % 4.1% % 4.0% 0 0.0% 0.0% % Detection % 7.2% % 8.7% 7 1.4% 13.0% % Diagnosis % 3.3% % 3.3% 2 1.6% 3.7% % Educational % 3.7% % 5.0% 1 0.9% 1.9% % Health Care Delivery % 6.2% % 7.7% 2 0.7% 3.7% % Health Program % 6.4% % 7.0% 3 1.0% 5.6% % Health Treatment % 29.8% % 29.1% % 18.5% % Health Prevention % 33.0% % 26.9% % 48.1% % Surgical % 6.3% % 8.2% 3 1.4% 5.6% % TOTAL % 100.0% % 100.0% % 1.0% % Each record may contain multiple age groups; a total of 3863 age groups were studied) 17
27 When outcome measures were categorized by age group (Table 12), cases of non-infectious disease/condition/abnormality were most frequently reported for perinates (39.0%). For neonates, life-years, QALYs or similar measures and cases of non-infectious disease/condition/abnormality were the most frequently reported outcomes (22.5%, 22.3% and 21.2%, respectively). For infants, QALYs or similar measures and cases of infectious disease/condition/abnormality were the most frequently reported outcomes (20.7% and 18.0%, respectively). Among both children and adolescents, the most frequently reported outcomes were QALYs or similar measures (23.2% and 19.1%). For adults included in these publications, cases of infectious disease/condition/abnormality was the most frequently reported outcome (24.1%). 18
28 Table 12 Publications by summary outcome and by age group (n=2630 records) (A = Perinate, Neonate, Infant: B = Child, Adolescent, Adult, Total) A Perinate (antenatal period) Neonate (newborn to < 1 month) Infant (1 month to < 1 year) OUTCOMES n row% col% n row% col% n row% col% Cases of complications/adverse events 9 3.8% 3.1% % 3.6% % 6.9% Cost 2 5.3% 0.7% % 0.6% % 1.3% Cases of cures/improvements/healing 4 1.4% 1.4% % 3.8% % 7.3% Cases of infectious disease/condition/abnormality % 15.3% % 13.0% % 18.0% Cases of injury 1 3.0% 0.3% 3 9.1% 0.5% % 0.7% Life Years % 15.3% % 22.5% % 15.0% Cases of non-infectious disease/condition/abnormality % 39.0% % 21.2% % 14.6% Other 2 3.6% 0.7% % 1.3% % 1.0% Changes in physiologic measure % 12.2% % 6.5% % 5.0% Changes in behavioural/psychosocial 1 0.9% 0.3% % 1.9% % 1.4% QALYs, or similar unit % 10.5% % 22.3% % 20.7% Changes in QOL 0 0.0% 0.0% 0 0.0% 0.0% % 1.0% Surrogate Health Outcomes 2 4.7% 0.7% % 1.1% % 0.9% Time Outcomes 0 0.0% 0.0% 8 6.4% 1.3% % 4.2% Unspecified 0 0.0% 0.0% % 0.2% % 0.3% Cases of vaccination 2 4.9% 0.7% 1 2.4% 0.2% % 1.6% TOTAL % 100.0% % 100.0% % 100.0% 19
29 Table 12, continued B OUTCOMES Child (> 1 year to 12 years) Adolescent (13 to 18 years) Adult (19 and older) TOTAL n row% col% n row% col% n row% col% n % Cases of complications/adverse events % 6.8% % 8.0% 4 1.7% 7.4% % Cost % 1.1% % 0.8% 0 0.0% 0.0% % Cases of cures/improvements/healing % 9.4% % 8.5% 5 1.8% 9.3% % Cases of infectious disease/condition/abnormality % 13.0% % 14.0% % 24.1% % Cases of injury % 1.1% % 1.2% 0 0.0% 0.0% % Life Years % 9.9% % 9.4% 6 1.2% 11.1% % Cases of non-infectious disease/condition/abnormality % 14.7% % 14.7% 8 1.2% 14.8% % Other % 1.8% % 1.7% 0 0.0% 0.0% % Changes in physiologic measure % 7.2% % 8.4% 3 1.1% 5.6% % Changes in behavioural/psychosocial % 3.6% % 6.2% 0 0.0% 0.0% % QALYs, or similar unit % 23.2% % 19.1% 9 1.1% 16.7% % Changes in QOL % 1.2% % 1.8% 2 5.1% 3.7% % Surrogate health outcomes % 1.3% % 1.3% 0 0.0% 0.0% % Time outcomes % 3.9% % 4.0% 3 2.4% 5.6% % Unspecified % 0.3% % 0.3% 0 0.0% 0.0% 9 0.2% Cases of vaccination % 1.5% 3 7.3% 0.5% 1 2.4% 1.9% % TOTAL % 100.0% % 100.0% % 100.0% % 20
30 3.7 Disease category Established disease classifications schema were applied to the publications in PEDE. Over the period covered by the database ( ), both ICD-9-CM and ICD-10 schema (18, 19) were used and are merged in this analysis. Overall, infective and parasitic diseases were most frequently studied in pediatric populations (29.2%), a trend which was consistent in both early and late periods (Table 13). Table 13. Publications in early ( ) and late ( ) periods by ICD9/10 disease category (n=2630) ICD 9/10 DISEASE Early ( ) Late ( ) TOTAL CLASSIFICATION n col% row% n col% row% n % Accidents, poisonings, and violence % 52.2% % 47.8% % Blood and blood-forming organs % 22.1% % 77.9% % Certain conditions originating in the % 70.0% % 30.0% % perinatal period Infective and parasitic % 24.9% % 75.1% % Pregnancy, childbirth and the % 44.4% % 55.6% % puerperium Circulatory system % 26.9% % 73.1% % Congenital anomalies % 46.8% % 53.2% % Dental % 97.0% 1 0.1% 3.0% % Digestive system % 30.1% % 69.9% % Nervous system and sensory organs % 22.1% % 77.9% % Genitourinary system % 24.7% % 75.3% % Musculoskeletal system 4 0.5% 16.0% % 84.0% % Skin and sub-cutaneous tissue 3 0.4% 11.5% % 88.5% % Respiratory system % 17.4% % 82.6% % Endocrine, nutrition and metabolism, % 30.3% % 69.7% % and immunity disorders External causes of morbidity and 0 0.0% 0.0% % 100.0% % mortality Factors influencing health status and 3 0.4% 3.2% % 96.8% % contact with health services General health % 62.3% % 37.7% % Mental disorders % 14.1% % 85.9% % Neoplasms % 36.1% % 63.9% % Symptoms, Signs and Ill-defined % 33.3% % 81.8% % Conditions Other 2 0.2% 66.7% 1 0.1% 33.3% 3 0.1% TOTAL % 30.7% % 69.1% % 21
31 When the ICD-9/10 disease classification was categorized by analytic technique (Table 14), CEAs and CUAs were most frequently conducted on infectious and parasitic diseases (24.6% and 40.6%, respectively). No CUAs were conducted in the area of dental diseases or general health conditions. In all disease categories, CEAs were most frequently conducted with the lowest proportion of CEAs being 39.3% for external causes of morbidity and mortality. 22
32 Table 14. Publications by ICD-9/10 disease classification and by analytic technique (n=2630 records) ICD 9/10 DISEASE CLASSIFICATION CBA CEA CMA CUA TOTAL n row% col% n row% col% n row% col% n row% col% n % Accidents, poisonings, and violence 6 8.7% 3.0% % 3.0% % 7.2% 5 7.2% 0.8% % Blood and blood-forming organs 4 3.1% 2.0% % 5.0% 5 3.8% 5.2% % 5.9% % Certain conditions originating in the 4 4.0% 2.0% % 4.5% 5 5.0% 5.2% % 2.4% % perinatal period Infective and parasitic % 40.9% % 24.6% % 10.3% % 40.6% % Pregnancy, childbirth and the puerperium % 5.9% % 9.0% 8 4.2% 8.2% % 2.7% % Circulatory system 3 5.8% 1.5% % 2.2% 3 5.8% 3.1% % 1.4% % Congenital anomalies % 13.3% % 8.1% 6 3.2% 6.2% % 2.9% % Dental % 2.0% % 1.6% 2 6.1% 2.1% 0 0.0% 0.0% % Digestive system 1 1.4% 0.5% % 3.5% 4 5.5% 4.1% % 1.4% % Nervous system and sensory organs 4 2.6% 2.0% % 5.1% 7 4.5% 7.2% % 8.9% % Genitourinary system 3 3.7% 1.5% % 2.5% 6 7.4% 6.2% % 4.6% % Musculoskeletal system 0 0.0% 0.0% % 1.1% 2 8.0% 2.1% % 0.6% % Skin and sub-cutaneous tissue 0 0.0% 0.0% % 1.0% 1 3.8% 1.0% % 1.3% % Respiratory system 2 1.1% 1.0% % 7.3% 3 1.7% 3.1% % 7.8% % Endocrine, nutrition and metabolism, and % 7.9% % 6.1% 4 2.6% 4.1% % 5.1% % immunity disorders External causes of morbidity and mortality % 2.5% % 0.6% 1 3.6% 1.0% % 1.7% % Factors influencing health status and % 5.4% % 3.1% 3 3.2% 3.1% % 4.6% % contact with health services General health % 4.9% % 3.2% 5 7.2% 5.2% 0 0.0% 0.0% % Mental disorders 5 5.9% 2.5% % 2.9% 3 3.5% 3.1% % 4.3% % Neoplasms 1 1.4% 0.5% % 2.7% % 10.3% % 2.5% % Symptoms, Signs and Ill-defined Conditions 2 3.7% 1.0% % 2.7% 2 3.7% 2.1% 4 7.4% 0.6% % Other 0 0.0% 0.0% % 0.2% 0 0.0% 0.0% 0 0.0% 0.0% 3 0.1% TOTAL % 100.0% % 100.0% % 100.0% % 100.0% % Abbreviations: CBA = cost benefit analysis; CEA = cost-effectiveness analysis; CMA = cost-minimization analysis; CUA = cost-utility analysis 23
33 When the ICD-9/10 disease classification was categorized by intervention type (Table 15), some associations were observed. For example, detection interventions were most frequently studied in congenital abnormalities (24.9%) while health prevention interventions were most frequently studied in infective and parasitic diseases (66.0%). 24
34 Table 15. Publications by ICD-9/10 disease classification and by intervention type (n=2630 records) (A = Detection, Diagnosis, Educational; B = Health Care Delivery, Health Care Program, Health Treatment; C = Surgical, Dental, Total) A ICD 9/10 DISEASE CLASSIFICATION Detection Diagnosis Educational n row% col% n row% col% n row% col% Accidents, poisonings, and violence 6 8.7% 1.4% 1 1.4% 1.3% 2 2.9% 2.5% Blood and blood-forming organs % 8.1% 4 3.1% 5.2% 0 0.0% 0.0% Certain conditions originating in the perinatal period % 3.1% 3 3.0% 3.9% 0 0.0% 0.0% Infective and parasitic % 16.0% % 18.2% 7 0.9% 8.9% Pregnancy, childbirth and the puerperium % 10.0% 1 0.5% 1.3% 1 0.5% 1.3% Circulatory system % 3.3% 4 7.7% 5.2% 2 3.8% 2.5% Congenital anomalies % 24.9% % 18.2% 1 0.5% 1.3% Dental 2 6.1% 0.5% 0 0.0% 0.0% 0 0.0% 0.0% Digestive system 6 8.2% 1.4% 6 8.2% 7.8% 1 1.4% 1.3% Nervous system and sensory organs % 11.7% 6 3.9% 7.8% 0 0.0% 0.0% Genitourinary system 4 4.9% 1.0% 7 8.6% 9.1% 0 0.0% 0.0% Musculoskeletal system % 0.7% 1 4.0% 1.3% 0 0.0% 0.0% Skin and sub-cutaneous tissue 0 0.0% 0.0% 1 3.8% 1.3% 2 7.7% 2.5% Respiratory system 7 3.9% 1.7% 4 2.2% 5.2% % 12.7% Endocrine, nutrition and metabolism, and immunity % 10.5% 4 2.6% 5.2% % 13.9% disorders External causes of morbidity and mortality 2 7.1% 0.5% 0 0.0% 0.0% % 5.1% Factors influencing health status and contact with health 3 3.2% 0.7% 0 0.0% 0.0% % 25.3% services General health 1 1.4% 0.2% 0 0.0% 0.0% 3 4.3% 3.8% Mental disorders 7 8.2% 1.7% 1 1.2% 1.3% % 13.9% Neoplasms % 2.2% 2 2.8% 2.6% 1 1.4% 1.3% Symptoms, signs and ill-defined conditions 1 1.9% 0.2% 4 7.4% 5.2% 3 5.6% 3.8% Other 0 0.0% 0.0% 0 0.0% 0.0% 0 0.0% 0.0% TOTAL % 100.0% % 100.0% % 100.0% 25
35 Table 15, continued B ICD 9/10 DISEASE CLASSIFICATION Health Care Delivery Health Program Health Treatment n row% col% n row% col% n row% col% Accidents, poisonings, and violence % 4.1% % 3.3% % 4.3% Blood and blood-forming organs 4 3.1% 2.4% 0 0.0% 0.0% % 10.1% Certain conditions originating in the 8 8.0% 4.7% % 10.4% % 5.8% perinatal period Infective and parasitic % 9.4% % 17.0% % 11.3% Pregnancy, childbirth and the % 16.5% % 17.0% % 4.9% puerperium Circulatory system 4 7.7% 2.4% 1 1.9% 0.5% % 3.0% Congenital anomalies % 5.9% 2 1.1% 0.9% % 2.8% Dental 0 0.0% 0.0% 0 0.0% 0.0% 0 0.0% 0.0% Digestive system 5 6.8% 2.9% 1 1.4% 0.5% % 2.8% Nervous system and sensory organs 4 2.6% 2.4% 3 1.9% 1.4% % 11.0% Genitourinary system 5 6.2% 2.9% 0 0.0% 0.0% % 3.0% Musculoskeletal system 0 0.0% 0.0% 0 0.0% 0.0% % 1.7% Skin and sub-cutaneous tissue 1 3.8% 0.6% 0 0.0% 0.0% % 2.4% Respiratory system % 10.0% % 6.1% % 12.3% Endocrine, nutrition and metabolism, % 7.6% % 8.5% % 6.9% and immunity disorders External causes of morbidity and % 2.4% 2 7.1% 0.9% % 0.5% mortality Factors influencing health status and 8 8.4% 4.7% % 5.7% % 1.6% contact with health services General health % 7.6% % 13.7% 5 7.2% 0.8% Mental disorders 5 5.9% 2.9% % 8.5% % 5.4% Neoplasms 5 6.9% 2.9% 3 4.2% 1.4% % 6.5% Symptoms, Signs and Ill-defined % 6.5% % 3.8% % 3.0% Conditions Other % 1.2% % 0.5% 0 0.0% 0.0% TOTAL % 100.0% % 100.0% % 100.0% 26
36 Table 15, continued C ICD 9/10 DISEASE CLASSIFICATION Surgical Dental TOTAL n row% col% n row% col% n % Accidents, poisonings, and violence 2 2.9% 1.5% 0 0.0% 0.0% % Blood and blood-forming organs 8 6.1% 6.0% 0 0.0% 0.0% % Certain conditions originating in the perinatal period 3 3.0% 2.3% 0 0.0% 0.0% % Infective and parasitic 5 0.7% 3.8% 0 0.0% 0.0% % Pregnancy, childbirth and the puerperium 3 1.6% 2.3% 0 0.0% 0.0% % Circulatory system 5 9.6% 3.8% 0 0.0% 0.0% % Congenital anomalies % 24.8% 0 0.0% 0.0% % Dental 0 0.0% 0.0% % 45.6% % Digestive system % 17.3% 1 1.4% 1.5% % Nervous system and sensory organs % 7.5% 1 0.6% 1.5% % Genitourinary system % 12.8% 0 0.0% 0.0% % Musculoskeletal system % 6.8% 0 0.0% 0.0% % Skin and sub-cutaneous tissue 1 3.8% 0.8% 0 0.0% 0.0% % Respiratory system 1 0.6% 0.8% 0 0.0% 0.0% % Endocrine, nutrition and metabolism, and immunity 5 3.2% 3.8% 0 0.0% 0.0% % disorders External causes of morbidity and mortality 1 3.6% 0.8% 0 0.0% 0.0% % Factors influencing health status and contact with 3 3.2% 2.3% % 32.4% % health services General health 0 0.0% 0.0% % 16.2% % Mental disorders 0 0.0% 0.0% 2 2.4% 2.9% % Neoplasms 3 4.2% 2.3% 0 0.0% 0.0% % Symptoms, Signs and Ill-defined Conditions 1 1.9% 0.8% 0 0.0% 0.0% % Other 0 0.0% 0.0% 0 0.0% 0.0% 3 0.1% TOTAL % 100.0% % 100.0% % 27
37 When ICD-9/10 disease classification was categorized by age group (Table 16), diseases of pregnancy, childbirth and the puerperium and congenital anomalies were the most frequently studied conditions in perinates (37.6% and 24.4%, respectively). Among the remaining age groups - neonates, infants, children, adolescents and adults - infective and parasitic diseases were the most frequently studied conditions (25.9%, 44.6%, 34.6%, 28.9% and 51.9%, respectively). 28
38 Table 16. Publications by ICD-9/10 disease classification and by age group (n=2630 records) (A = Perinate, Neonate, Infant; B = Child, Adolescent, Adult, Total) A ICD 9/10 DISEASE CLASSIFICATION Perinate (antenatal period) Neonate (newborn to < 1 month) Infant (1 month to < 1 year) n row% col% n row% col% n row% col% Accidents, poisonings, and violence 0 0.0% 0.0% 5 7.2% 0.8% % 3.4% Blood and blood-forming organs % 5.1% % 5.9% % 3.5% Certain conditions originating in the perinatal period % 5.4% % 11.3% % 2.8% Infective and parasitic % 7.5% % 25.9% % 44.6% Pregnancy, childbirth and the puerperium % 37.6% % 12.2% 6 3.2% 0.9% Circulatory system 2 3.8% 0.7% % 1.7% % 1.5% Congenital anomalies % 24.4% % 12.2% 6 3.2% 0.9% Dental 0 0.0% 0.0% 0 0.0% 0.0% 3 9.1% 0.5% Digestive system 0 0.0% 0.0% % 1.7% % 3.8% Nervous system and sensory organs 3 1.9% 1.0% % 5.3% % 6.7% Genitourinary system 2 2.5% 0.7% % 1.8% % 2.8% Musculoskeletal system 1 4.0% 0.3% 2 8.0% 0.3% % 0.5% Skin and sub-cutaneous tissue 0 0.0% 0.0% % 0.6% % 1.7% Respiratory system 9 5.1% 3.1% % 5.0% % 8.1% Endocrine, nutrition and metabolism, and immunity disorders % 3.4% % 5.6% % 4.4% External causes of morbidity and mortality 2 7.1% 0.7% % 0.8% % 0.8% Factors influencing health status and contact with health services 2 2.1% 0.7% % 3.5% % 3.4% General health % 9.2% % 2.9% % 1.8% Mental disorders 1 1.2% 0.3% 2 2.4% 0.3% 5 5.9% 0.8% Neoplasms 0 0.0% 0.0% 3 4.2% 0.5% % 3.2% Symptoms, Signs and Ill-defined Conditions 0 0.0% 0.0% % 1.5% % 3.5% Other 0 0.0% 0.0% % 0.2% % 0.5% TOTAL % 100.0% % 100.0% % 100.0% 29
39 Table 16, continued B Child (> 1 year to 12 years) Adolescent (13 to 18 years) Adult (19 and older) ICD 9/10 DISEASE CLASSIFICATION n row% col% n row% col% n row% col% n % Accidents, poisonings, and violence % 4.2% % 4.4% 2 2.9% 3.7% % Blood and blood-forming organs % 5.2% % 6.9% 3 2.3% 5.6% % Certain conditions originating in the perinatal period % 0.7% 1 1.0% 0.2% 0 0.0% 0.0% % Infective and parasitic % 34.6% % 28.9% % 51.9% % Pregnancy, childbirth and the puerperium 2 1.1% 0.1% 8 4.2% 1.4% 1 0.5% 1.9% % Circulatory system % 2.1% % 3.9% 2 3.8% 3.7% % Congenital anomalies 2 1.1% 0.1% 8 4.3% 1.4% 1 0.5% 1.9% % Dental % 2.1% % 2.5% 0 0.0% 0.0% % Digestive system % 4.2% % 3.5% 0 0.0% 0.0% % Nervous system and sensory organs % 7.2% % 4.2% 1 0.6% 1.9% % Genitourinary system % 4.0% % 4.4% 1 1.2% 1.9% % Musculoskeletal system % 0.9% % 2.5% 2 8.0% 3.7% % Skin and sub-cutaneous tissue % 1.4% % 1.2% 0 0.0% 0.0% % Respiratory system % 8.3% % 7.4% 5 2.8% 9.3% % Endocrine, nutrition and metabolism, and immunity % 6.6% % 5.4% 4 2.6% 7.4% % disorders External causes of morbidity and mortality % 1.3% % 1.5% 0 0.0% 0.0% % Factors influencing health status and contact with health % 4.3% % 3.9% 1 1.1% 1.9% % services General health % 1.5% % 1.2% 1 1.4% 1.9% % Mental disorders % 4.0% % 7.9% 0 0.0% 0.0% % Neoplasms % 4.3% % 4.4% 2 2.8% 3.7% % Symptoms, signs and ill-defined conditions % 2.6% % 2.5% 0 0.0% 0.0% % Other % 0.2% % 0.3% 0 0.0% 0.0% 3 0.2% TOTAL % 100.0% % 100.0% % 100.0% % Total 30
Course Outline Introduction to ICD-10 Coding Course
Course Outline Introduction to ICD-10 Coding Course Module 1 An Introduction to Clinical Coding History and Background of the International Classification of Diseases and Related Health Problems Features
More informationICD-10 Back Up The Truck. Andrea Romero, RHIT, CCS, CPC NMHIMA Leadership Conference April 10, 2014
ICD-10 Back Up The Truck Andrea Romero, RHIT, CCS, CPC NMHIMA Leadership Conference April 10, 2014 ICD-10 IS DELAYED AGAIN Classification Structure ICD-9-CM Infectious and Parasitic Diseases (001 139)
More informationIsle of Wight Joint Strategic Needs Assessment: Core Dataset 2009
Isle of Wight Joint Strategic Needs Assessment: Core Dataset 2009 Domain: Burden of Ill Health Indicator: Hospital Admissions - Top 10 Causes Sub-Domain: Misc Indicator References: JSNA Core Dataset number
More informationICD. International Classification of Diseases
ICD International Classification of Diseases ICD international standard diagnostic classification for general epidemiological health management purposes clinical use analysis of the general health situation
More informationNon-covered ICD-10-CM Codes for All Lab NCDs
Non-covered ICD-10-CM s for All Lab NCDs This section lists codes that are never covered by Medicare for a diagnostic lab testing service. If a code from this section is given as the reason for the test,
More informationDiagnosis-specific morbidity - European shortlist
I Certain infectious and parasitic diseases 1 Tuberculosis A15-A19 X X Z 2 Sexually transmitted diseases (STD) A50-A64 Y Z 3 Viral hepatitis (incl. hepatitis B) B15-B19 X Z 4 Human immunodeficiency virus
More informationPrioritized ShortList MORBIDITY
Report on in-depth analysis of pilot studies in 16 Member States on diagnosis-specific morbidity statistics Annex 2 (Rev 11_11_13) Prioritized ShortList MORBIDITY Legend: X recommended for collection Y
More informationIntegrating ICD-10s in SmarTrack
Paul Russell BSN, RN Midas+ Solutions Educator Objectives Discuss change from ICD-9 to ICD-10 Define Indicator using ICD-10 Create a Worklist using ICD-10 2 2016 Midas+ Symposium May 23-25 Tucson, AZ 1
More informationChild mortality of children aged 5-15 years in the UK and Sweden: a comparison
Child mortality of children aged 5-15 years in the UK and Sweden: a comparison Parag Tambe, Helen M Sammons, Imti Choonara Academic Unit of Child Health, University of Nottingham, Derbyshire Children s
More informationThe Nottingham eprints service makes this work by researchers of the University of Nottingham available open access under the following conditions.
Tambe, Parag and Sammons, Helen M. and Choonara, Imti (2016) Child mortality of children aged 5-15 years in the UK and Sweden: a comparison. Archives of Disease in Childhood, 101 (4). pp. 409-410. ISSN
More informationICD-10-CM Foundation Training
ICD-10-CM Foundation Training 1 Objectives What is ICD-10? Benefits of ICD-10 ICD-10 Impacts Important Facts about ICD-10 Where to Get More Information Codebook Structure Conventions Overview Code Structure
More informationNon-covered ICD-10-CM Codes for All Lab NCDs
Non-covered ICD-10-CM s for All Lab NCDs This section lists codes that are never covered by Medicare for a diagnostic lab testing service. If a code from this section is given as the reason for the test,
More informationOptum360 Learning: Detailed Instruction for Appropriate ICD-10-CM Coding
Optum360 Learning: Detailed Instruction for Appropriate Coding An educational guide to the structure, conventions, and guidelines of coding 2017 Contents Section 1: Introduction...1 Documentation...7 Documentation
More informationCochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library)
A systematic review of smoking cessation and relapse prevention interventions in parents of babies admitted to a neonatal unit (after delivery) Divya Nelson, Sarah Gentry, Caitlin Notley, Henry White,
More informationCENTRAL TEXAS COLLEGE SYLLABUS FOR HITT 1341 CODING AND CLASSIFICATION SYSTEMS. Semester Hours Credit: 3
I. INTRODUCTION CENTRAL TEXAS COLLEGE SYLLABUS FOR HITT 1341 CODING AND CLASSIFICATION SYSTEMS INSTRUCTOR: Semester Hours Credit: 3 OFFICE HOURS: A. Fundamentals of coding rules, conventions, and guidelines
More informationNon-covered ICD-10-CM Codes for All Lab NCDs
Non-covered ICD-10-CM Codes for All Lab NCDs This section lists codes that are never covered by Medicare for a diagnostic lab testing service. If a code from this section is given as the reason for the
More informationA chapter by chapter look at the ICD-10-CM code set Coding Tip Sheet
Coding Tip Sheet Chapter 1 - Certain Infectious and Parasitic Diseases Terminology changes: The term Sepsis (ICD-10-CM) has replaced the term Septicemia (ICD-9-CM) Urosepsis is a nonspecific term and is
More informationUniversity of Bristol - Explore Bristol Research
Hunt, L., Ben-Shlomo, Y., Whitehouse, M., Porter, M., & Blom, A. (2017). The Main Cause of Death Following Primary Total Hip and Knee Replacement for Osteoarthritis: A Cohort Study of 26,766 Deaths Following
More informationFlorida EMS Advisory Council. Chief Darrel Donatto, Chair. January 18, 2018
Florida EMS Advisory Council Chief Darrel Donatto, Chair January 18, 2018 EMSAC Data Committee Meeting A G E N D A Welcome/ Opening Remarks Review/Approval of Meeting Records Update on Action Items Update
More informationIII. KNOWLEDGE BASE ON THE 65 CAUSES OF DEATH (EUROSTAT SHORT LIST)
III. KNOWLEDGE BASE ON THE 65 CAUSES OF DEATH (EUROSTAT SHORT LIST) This section of the report on the 'Knowledge base on the 65 causes of death' comprises two parts: a published studies database and an
More informationEconomic evaluation of health promotion activities for older people conceptual questions
Economic evaluation of health promotion activities for older people conceptual questions Pro Health 65+ Health promotion and prevention of risk Action for Seniors EUHEA Conference 2016, Hamburg Know the
More informationAHIMA Academy for ICD-10-CM/PCS: Building Expert Trainers in Diagnosis and Procedure Coding
AGENDA AHIMA Academy for ICD-10-CM/PCS: Building Expert Trainers in Diagnosis and Procedure Coding Day 1 7:30 8:00 am Registration Orientation to Training Materials and Instructional Methods ICD-10-CM
More informationHospital admissions in migrant and native groups in the Netherlands
Statistics Netherlands Division of Social and Spatial Statistics Department of Personal Data Registers E-mail: gvry@cbs.nl; abun@cbs.nl Hospital admissions in migrant and native groups in the Netherlands
More informationMedicare Update or Planning for ICD-10. Maureen Brooks February 20, 2014
Medicare Update or Planning for ICD-10 Maureen Brooks February 20, 2014 Partial Code Freeze October 1, 2013 a partial update to include new technology and new diseases published October 1, 2014 no update
More informationICD-9-CMCoding I Common Course Outline
ICD-9-CMCoding I Common Course Outline Course Information Organization South Central College Revision History 2008-2009 Course Number HC 1920 Department Health Careers Total Credits 3 Description This
More informationAppropriate Use of 7 th Character in ICD 10 CM
Appropriate Use of 7 th Character in ICD 10 CM Jameel Ahmed RHIA,CCS Corporate, Group HIM Manager SEHA - Abu Dhabi Health Services Co SEHA: Abu Dhabi Healthservices 18,000 Employees 12 Hospitals 57 Ambulatory
More informationAll-Cause Hospitalizations, Waterloo Region and Ontario, 2013, 2014, 2015
All-Cause Hospitalizations, Waterloo Region and Ontario, 2013, 2014, 2015 Table 1. Number of hospitalizations and age-standardized hospitalization rate per 100,000 population, by place of residence, Waterloo
More informationEconomic evaluation of health promotion and primary prevention actions for older people a systematic review
Economic evaluation of health promotion and primary prevention actions for older people a systematic review Katarzyna Dubas-Jakóbczyk, Ewa Kocot, Katarzyna Kissimova-Skarbek, (Jagiellonian University Medical
More informationAboriginal and Torres Strait Islander Health Performance Framework Report
Aboriginal and Torres Strait Islander Health Performance Framework 26 Report Report Findings Tier 1: Health Status and Outcomes Improvements: Mortality Infant Mortality Deaths due to Circulatory Disease
More informationPHO: Metadata for Mortality from Avoidable Causes
Snapshots @ PHO: Metadata for Mortality from Avoidable Causes This indicator captures individuals under 75 years of age who have died with a condition considered as avoidable recorded as the primary cause
More informationPreconception care: Maximizing the gains for maternal and child health
POLICY BRIEF WHO/FWC/MCA/13.02 Preconception care: Maximizing the gains for maternal and child health A new WHO report shows that preconception care has a positive impact on maternal and child health outcomes
More informationHI-1051: Certified Professional Coder Preparation Course
Course Code/Title: HI-1051: Certified Professional Coder Preparation Course Course Hours: 320 Duration (wks): 16 weeks Chapter 1 The Business of Medicine Coding as a Profession The Difference between Hospital
More informationInjuries and Illnesses of Vietnam War POWs Revisited: III. Marine Corps Risk Factors LT Saima S. Raza, MSC, USN, Jeffrey L. Moore, John P.
Injuries and Illnesses of Vietnam War POWs Revisited: III. Marine Corps Risk Factors LT Saima S. Raza, MSC, USN, Jeffrey L. Moore, John P. Albano Operation Homecoming (O/H), the negotiated release of 566
More informationInjury Chronic Disease Infant Mortality Maternal & Child Health Infectious Disease Life Expectancy
Visit WatchUsThrive.org to learn more Welcome to the Community Health Pathway of WeTHRIVE! SM Here you will find a brief Community Health Assessment for your community. This will provide you with health
More informationPROJECT INFORMATION DOCUMENT (PID) APPRAISAL STAGE Report No.: PIDA Project Name. Region. Country. Sector(s) Health (100%) Theme(s)
Public Disclosure Authorized Public Disclosure Authorized Public Disclosure Authorized Public Disclosure Authorized PROJECT INFORMATION DOCUMENT (PID) APPRAISAL STAGE Report No.: PIDA62480 Project Name
More informationHighlights of the NEW 2017 Codes ICD-10- CM
Highlights of the NEW 2017 Codes ICD-10- CM Maine HIMA September 22, 2016 ICD-10-CM o 1943 New Codes o 422 Revised Codes o 305 Deleted Codes Overall Picture o Which revisions apply most to your facility?
More informationInjuries and Illnesses of Vietnam War POWs Revisited: II. Army Risk Factors LT Saima S. Raza, MSC, USN, Jeffrey L. Moore, John P.
Injuries and Illnesses of Vietnam War POWs Revisited: II. Army Risk Factors LT Saima S. Raza, MSC, USN, Jeffrey L. Moore, John P. Albano Operation Homecoming (O/H), the negotiated release of 566 US Servicemen
More informationMalignancy ; 191.6; Malignant neoplasm of brain
APPENDIX 15 Comparison of ICD-9 Diagnostic Codes Used to Identify Children with Life-Threatening or Life-Limiting or Comple Chronic Conditions By Five CHI PACC Programs ICD-9 Category ICD-9 Description
More informationSelected tables standardised to Segi population
Selected tables standardised to Segi population LIST OF TABLES Table 4.2S: Selected causes of death, all-ages, 2000 2004 (Segi Standard) Table 5.3S: Public hospitalisations by major cause of admission
More informationStudy population The study population comprised HIV-infected pregnant women seeking antenatal care.
Cost-effectiveness of nevirapine to prevent mother-to-child HIV transmission in eight African countries Sweat M D, O'Reilly K R, Schmid G P, Denison J, de Zoysa I Record Status This is a critical abstract
More informationThe Cochrane Library Impact Factor Data Pack
Attachment 2 The Cochrane Library Impact Factor Data Pack When considering the data presented below, please be aware of the following: The dataset we have used to generate impact factors for individual
More informationMaureen Brooks, CPC HMWC H.E.L.P September 6, 2012
Maureen Brooks, CPC HMWC H.E.L.P September 6, 2012 The compliance date for upgrading to Version 5010 standards d for electronic health transactions was January 1, 2012; CMS enforcement discretion is in
More informationPUBLIC HEALTH IN THE REPUBLIC OF BELARUS
NATIONAL STATISTICAL COMMITTEE OF THE REPUBLIC OF BELARUS PUBLIC HEALTH IN THE REPUBLIC OF BELARUS Statistical book MINSK 2014 EDITORIAL BOARD: Vladimir Zinovsky Chair Irina Kostevich, Irina Kangro, Elena
More informationThe Aboriginal Maternal and Infant Health Service: a decade of achievement in the health of women and babies in NSW
The Aboriginal Maternal and Infant Health Service: a decade of achievement in the health of women and babies in NSW Elisabeth Murphy A,B and Elizabeth Best A A Maternity, Children and Young People s Health
More information0301 Anemia Others. Endocrine nutritional and metabolic disorders Others Vascular dementia and unspecified dementia
Certain infectious and parasitic diseases 0101 Intestinal infectious diseases 0102 Tuberculosis 0103 Infections with a predominantly sexual mode of transmission 0104 Viral infections characterized by skin
More informationThe Cochrane Library 2014 CRG Impact Factor and Usage report
The Cochrane Library 2014 CRG Impact Factor and Usage report When considering the citation data presented below, please be aware of the following: The data used to generate Impact Factors for individual
More informationpresented by the APMA Coding Committee LIVE: January 9, pm ET
Welcome to the APMA ICD-10 is Here Webinar Series presented by the APMA Coding Committee LIVE: January 9, 2014 8pm ET 1 Tonight s Webinar: ICD-10-CM Timelines / Rules / Basics 2 Welcome to the APMA ICD-10-CM
More informationAttending Physician s Statement
( Form A A This form is used for claiming the social insurance benefit. This form should be completed and signed by the attending physician outpatient and One form for each month, one form for hospitalization
More informationPortland Area Health Priorities
Portland Area Indian Health Service Portland Area Health Priorities CAPT Thomas Weiser, MD, MPH Medical Epidemiologist Portland Area Budget Formulation Meeting Portland, November 30, 2017 Overview Brief
More informationMethods for the Estimation of the NICE Cost Effectiveness Threshold
Methods for the Estimation of the NICE Cost Effectiveness Threshold Karl Claxton, 1,2 Steve Martin, 2 Marta Soares, 1 Nigel Rice, 1,2 Eldon Spackman, 1 Sebastian Hinde, 1 Nancy Devlin, 3 Peter C Smith,
More informationMethods for the Estimation of the NICE Cost Effectiveness Threshold
Methods for the Estimation of the NICE Cost Effectiveness Threshold Karl Claxton, 1,2 Steve Martin, 2 Marta Soares, 1 Nigel Rice, 1,2 Eldon Spackman, 1 Sebastian Hinde, 1 Nancy Devlin, 3 Peter C Smith,
More informationComprehensive cost-utility analysis of newborn screening strategies Carroll A E, Downs S M
Comprehensive cost-utility analysis of newborn screening strategies Carroll A E, Downs S M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS
More informationSupplementary Online Content
Supplementary Online Content Acuna SA, Fernandes KA, Daly C, et al. Cancer mortality among recipients of solidorgan transplantation in Ontario, Canada. JAMA Oncol. Published online January 7, 2016. doi:10.1001/jamaoncol.2015.5137
More information2015 Emergency Department Data Annual Report
2015 Emergency Department Data Annual Report Health Systems Epidemiology Program Epidemiology and Response Division New Mexico Department of Health 2015 Emergency Department Data New Mexico Department
More informationPrecyse University ICD-10 Education Tracks
Precyse University ICD-10 Education Tracks The following information will help you understand the Precyse University ICD-10 Educational Tracks. Each impacted population requires specific education to prepare
More informationPublic Health Outcomes Framework. Summary for Sefton. Indicators at a glance (May 2017)
Public Health Outcomes Framework Indicators at a glance (May 2017) Notes: - Value cells are shaded red, amber or green to show significance compared to England, or where the value can be benchmarked against
More informationPublic Health Outcomes Framework. Summary for East Sussex. Indicators at a glance (February 2017)
Public Health Outcomes Framework Indicators at a glance (February 2017) Notes: - Value cells are shaded red, amber or green to show significance compared to England, or where the value can be benchmarked
More informationTABLE C-1 RESIDENT DEATHS, LIVE BIRTHS, FETAL, INFANT, NEONATAL, AND MATERNAL DEATHS: PENNSYLVANIA,
TABLE C-1 RESIDENT DEATHS, LIVE BIRTHS, FETAL, INFANT, NEONATAL, AND MATERNAL DEATHS: PENNSYLVANIA, 1950-1997 - TOTAL LIVE FETAL INFANT NEONATAL MATERNAL DEATHS BIRTHS DEATHS DEATHS DEATHS DEATHS ----------------------------------------------------------------------------------
More informationEpisodes of Care Risk Adjustment
Episodes of Care Risk Adjustment Episode Types Wave 1 Asthma Acute Exacerbation Perinatal Total Joint Replacement Wave 2 Acute Percutaneous Coronary Intervention COPD Acute Exacerbation Non-acute Percutaneous
More informationMeet the Presenter. Welcome to PMI s Webinar Presentation. Understanding the ICD- 10-CM Guidelines. On the topic:
Welcome to PMI s Webinar Presentation Brought to you by: Practice Management Institute pmimd.com Meet the Presenter On the topic: Understanding the ICD- 10-CM Guidelines Libby Purser, CHI, CMC, CMIS, CMOM,
More informationCOMPLETING THE MEDICAL CERTIFICATE OF DEATH
COMPLETING THE MEDICAL CERTIFICATE OF DEATH This is an information bulletin for physicians. A Handbook is available on the BC Vital Statistics website http://www.vs.gov.bc.ca located in Service Information
More informationINDEX FOR 3 AND 4 DIGIT DIAGNOSTIC CODES (ICD9)
INDEX FOR 3 AND 4 DIGIT DIAGNOSTIC CODES (ICD9) INFECTIONS AND PARASITIC DISEASES 001-009.3 Intestinal and Infectious Diseases 010-018.9 Tuberculosis 020-027.9 Zoonotic Bacterial Diseases 030-041.9 Other
More informationTHAILAND THAILAND 207
THAILAND 27 List of Country Indicators Selected Demographic Indicators Selected demographic indicators Child Mortality and Nutritional Status Trends in neonatal, infant and child mortality rates Distribution
More informationICD- 10- CM General Coding Guidelines and Mapping
PECAA Professional Eye Care Associates of America ICD- 10- CM General Coding Guidelines and Mapping Introduction The International Classification of Diseases, 10 th revision, Clinical Modifications (ICD-
More informationWHO analysis of causes of maternal death: a proposed protocol for a global systematic review
WHO analysis of causes of maternal death: a proposed protocol for a global systematic review R. Champaneria 1, J. Daniels 1,2, K.S. Khan 1, L. Say 3, A.M. Gulmezoglu 3, S. Cousens 4, A.J.Howman 2 1 Academic
More informationSmartVA Analyze Outputs Interpretation Sheet
SmartVA Analyze Outputs Interpretation Sheet SmartVA-Analyze uses an algorithm called Tariff 2.0 to assign the cause of death based on the details of the verbal autopsy (VA) interview. The output from
More informationBrant County Community Health Status Report: 2001 OVERVIEW
Brant County Community Health Status Report: 2001 OVERVIEW Brantford County of Brant Brant County Health Unit and Grand River District Health Council April 2001 Brant County Community Health Status Report:
More informationPopulation Population Projections 2005, Region of Peel and Municipalities Mississauga Brampton Caledon Peel Male Female
Peel Health Facts Population Population Projections 2005, Region of Peel and Municipalities Mississauga Brampton Caledon Peel Male 322,000 195,000 28,000 545,000 Female 330,000 199,000 28,000 557,000 Total
More informationPertussis in adolescents and adults: should we vaccinate Lee G M, LeBaron C, Murphy T V, Lett S, Schauer S, Lieu T A
Pertussis in adolescents and adults: should we vaccinate Lee G M, LeBaron C, Murphy T V, Lett S, Schauer S, Lieu T A Record Status This is a critical abstract of an economic evaluation that meets the criteria
More informationPrioritized research questions for adolescent HIV testing, treatment and service delivery
Prioritized research questions for adolescent HIV testing, treatment and service delivery The World Health Organization (WHO) and the Collaborative Initiative for Paediatric HIV Education and Research
More informationPROSPERO International prospective register of systematic reviews
PROSPERO International prospective register of systematic reviews Preventing falls and associated mortality in older people: an umbrella review of systematic reviews Mukesh Dherani, Stefanie Buckner, Daniel
More informationTransitional Doctor of Physical Therapy Pediatric Science
Transitional Doctor of Physical Therapy Pediatric Science Jane Sweeney PT, PhD, PCS, FAPTA Program Director jsweeney@rmuohp.edu 122 East 1700 South Provo, UT 84606 801.375.5125 866.780.4107 Toll Free 801.375.2125
More informationTuberculosis Mortality in Karnataka
Tuberculosis Mortality in Karnataka N Suseendra Babu $ NTI Bulletin Vol 44/3&4, 2008, Summary An analysis was carried out to assess the position of Tuberculosis (TB) among all the causes of death. The
More informationMid-West Local Collaborative Priority Area: Kensington Chinatown, Focus on Low Urgency ED Visits
Mid-West Local Collaborative Priority Area: Kensington Chinatown, Focus on Low Urgency ED Visits Preliminary Results April 27, 2017 Contents 1. Kensington Chinatown map, background and methodology/considerations/limitations
More informationIntroduction to the POWER Study Chapter 1
ONTARIO WOMEN S HEALTH EQUITY REPORT Introduction to the POWER Study Chapter 1 AUTHORS Susan K. Shiller, MSc Arlene S. Bierman, MD, MS, FRCPC INSIDE Why do we need a Women s Health Equity Report in Ontario?
More informationReport on Cancer Statistics in Alberta. Kidney Cancer
Report on Cancer Statistics in Alberta Kidney Cancer November 29 Surveillance - Cancer Bureau Health Promotion, Disease and Injury Prevention Report on Cancer Statistics in Alberta - 2 Purpose of the Report
More informationCombination therapy compared to monotherapy for moderate to severe Alzheimer's Disease. Summary
Combination therapy compared to monotherapy for moderate to severe Alzheimer's Disease Summary Mai 17 th 2017 Background Alzheimer s disease is a serious neurocognitive disorder which is characterized
More informationNorth Carolina Inpatient Hospital Discharge Data - Data Dictionary FY 2016 Alphabetic List of Variables and Attributes Standard Research File
North Carolina Inpatient Hospital Discharge Data - Data Dictionary FY 2016 Alphabetic List of Variables and Attributes Standard Research File For a standard research file request one of three variables
More informationNon-covered ICD-10-CM Codes for All Lab NCDs
Non-covered ICD-10-CM s for All Lab NCDs This section lists codes that are never covered by Medicare for a diagnostic lab testing service. If a code from this section is given as the reason for the test,
More informationNUTRITIONAL AND METABOLIC DISEASES CAUSE PREMATURE DEATHS IN BIHOR COUNTY?
Analele Universităţii din Oradea, Fascicula: Ecotoxicologie, Zootehnie si Tehnologii de Industrie Alimentara, Vol. XV/B Anul15, 2016 NUTRITIONAL AND METABOLIC DISEASES CAUSE PREMATURE DEATHS IN BIHOR COUNTY?
More informationFirst Nations Health Status Report - Alberta Region
Your health and safety our priority. Votre santé et votre sécurité notre priorité. First Nations Health Status Report - Alberta Region 29-21 First Nations and Inuit Health Alberta Region VISION: To be
More informationDiabetes in Manitoba 1989 to 2006 R E P O R T O F D I A B E T E S S U R V E I L L A N C E
Diabetes in Manitoba 1989 to 2006 R E P O R T O F D I A B E T E S S U R V E I L L A N C E May 2009 Key Results Diabetes Prevalence Manitoba has experienced a considerable growth in the number of people
More informationData Sources, Methods and Limitations
Data Sources, Methods and Limitations The communicable diseases contained in this report are reportable to the local Medical Officer of Health under the jurisdiction of the Health Protection and Promotion
More informationSummary Report Report on Cancer Statistics in Alberta. February Surveillance and Health Status Assessment Cancer Surveillance
Summary Report 2008 Report on Cancer Statistics in Alberta February 2011 November 25, 2011 ERRATUM: Summary Report, 2008 Report on Cancer Statistics in Alberta There was an error in the spelling of prostate
More informationTABLE I-1: RESIDENT INFANT DEATHS PER 1,000 LIVE BIRTHS, BY RACE AND ETHNICITY, FLORIDA AND UNITED STATES, CENSUS YEARS AND
TABLE I-1: RESIDENT INFANT DEATHS PER 1,000 LIVE BIRTHS, BY RACE AND ETHNICITY, FLORIDA AND UNITED STATES, CENSUS YEARS 1970-2000 AND 2004-2014 FLORIDA 1 UNITED STATES 1 YEAR WHITE2 BLACK2 HISPANIC3 WHITE2
More informationHealth Economics & Decision Science (HEDS) Discussion Paper Series
School of Health And Related Research Health Economics & Decision Science (HEDS) Discussion Paper Series Understanding the experience and impact of living with a vascular condition from the patients perspective:
More informationEvidence-Based Population Health Management through Analytics
Evidence-Based Population Health Management through Analytics Presented to: Human Factor Analytics, Inc. Slide 1 What can a geological principle teach us about risk management? Human Factor Analytics,
More informationLeading causes of death among Minneapolis residents,
Leading causes of death among Minneapolis residents, 2005-2014 Leading causes of death in Minneapolis and the U.S. March 2016 Final Report (Revised May 2016) T he five leading causes of death among Minneapolis
More informationBlue represents coding updates. G0389 with diagnosis V81.2, V15.82, or with diagnosis V79.1, or
An Independent Licensee of the Blue Cross and Blue Shield Association Preventive Care Services The following is a list of preventive services (HCP rider) along with the diagnoses and procedure codes that
More informationValidating and Grouping Diagnosis
Validating and Grouping Diagnosis DataSci Consulting CMS SAS User Group Conference, 2007 Grouping Grouping Grouping Goals Cover basic concepts about diagnoses and codes Share some examples Provide useful,
More informationProposed Maternal and Child Health Funding Highlights Fiscal Year 2013 Senate Labor, Health and Human Services Appropriations
Proposed Maternal and Child Health Funding Highlights Fiscal Year 2013 Senate Labor, Health and Human Services Appropriations Background: On June 14 th the Senate Appropriations Committee approved the
More informationGENERAL PROFILE OF PEDIATRICS
GENERAL PROFILE OF PEDIATRICS HUANG Guo-ying, M.D. ( 黄国英教授 ) Professor, Department of Pediatrics Shanghai Medical College Fudan University gyhuang@shmu.edu.cn Requirements in this lesson To be familiar
More informationNSW INJURY PROFILE: During to
I R M R C N S W I n j u r y R i s k Management Research centre NSW INJURY PROFILE: A Review of Injury Hospitalisations During 1989 1990 to 2003 2004 Andrew Hayen and Rebecca Mitchell NSW Injury Risk Management
More informationCASE-MIX ANALYSIS ACROSS PATIENT POPULATIONS AND BOUNDARIES: A REFINED CLASSIFICATION SYSTEM DESIGNED SPECIFICALLY FOR INTERNATIONAL USE
CASE-MIX ANALYSIS ACROSS PATIENT POPULATIONS AND BOUNDARIES: A REFINED CLASSIFICATION SYSTEM DESIGNED SPECIFICALLY FOR INTERNATIONAL USE A WHITE PAPER BY: ROBERT MULLIN, MD JAMES VERTREES, PHD RICHARD
More information2012 HOSPITAL INPATIENT DISCHARGE DATA
2012 HOSPITAL INPATIENT DISCHARGE DATA NM OH Mexico Po Comm Health Systems Epidemiology Program Epidemiology and Response Division New Mexico Department of Health Revised March 2014 The New Mexico Department
More informationCalifornia. Maternal and Child Health Block Grant 2018
California Maternal and Child Health Block Grant 2018 The Maternal and Child Health Services Block Grant, Title V of the Social Security Act, is the only federal program devoted to improving the health
More informationThis proposal represents a significant improvement over the previous version.
May 9, 2018 VIA ELECTRONIC MAIL Donna Pickett, MPH, RHIA ICD-10 Coordination and Maintenance Committee National Center for Health Statistics 3311 Toledo Road Hyattsville, Maryland 20782 Dear Ms. Pickett:
More information5.2 Main causes of death Brighton & Hove JSNA 2013
Why is this issue important? We need to know how many people are born and die each year and the main causes of their deaths in order to have well-functioning health s. 1 Key outcomes Mortality rate from
More informationCost-effectiveness of strategies to reduce mother-to-child HIV transmission in Mexico, a lowprevalence
Cost-effectiveness of strategies to reduce mother-to-child HIV transmission in Mexico, a lowprevalence setting Rely K, Bertozzi S M, Avila-Figueroa C, Guijarro M T Record Status This is a critical abstract
More information