Jornada sobre INVESTIGACIÓN CLÍNICA EN PEDIATRÍA. Cristina Calvo Hospital Universitario La Paz
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1 Jornada sobre INVESTIGACIÓN CLÍNICA EN PEDIATRÍA Cristina Calvo Hospital Universitario La Paz
2
3 INDEX 1. Research structure 1. Clinical Trials Unit 2. Pediatric Research Groups 2. Research Networks 3
4 RESEARCH STRUCTURE
5 CLINICAL TRIALS UNIT (UCICEC) 5
6 LA PAZ: PEDIATRIC CLINICAL TRIAL UNIT (UCICEC) DIRECTORY ON PEDIATRIC RESEARCH UNITS 2º FLOOR Mother & child hospital. 6
7 LA PAZ: PEDIATRIC CLINICAL TRIAL UNIT (UCICEC) Areas of Pediatric Clinical Trials Alberto Borobia Clinical Pharmacologist Allergy Anesthesia and Resuscitation Clinical Pharmacology Biochemistry Cardiology Children's Cardiology Cardiac surgery for children General Surgery Maxillofacial Surgery Orthopedic Surgery and Traumatology Pediatric surgery Pediatric Intensive Care Dermatology Digestive / Gastroenterology Endocrinology Nursing Pharmacy Clinical Pharmacology Gynecology Pediatric Hemato-oncology Hematology Hepatology Pediatric Infectious-Tropical Diseases and Vaccines Immunology Immunology Medical and Molecular Genetic Institute Internal Medicine Microbiology Nephrology Neonatology Pneumology Neurology Child nutrition Obstetrics / Gynecology Ophthalmology Oncology General Pediatrics Psychiatry Radiology Rehabilitation Rheumatology Traumatology Childhood Pain Unit Electrophysiology Sleep Unit HIV Unit Pediatric Emergencies 7
8 LA PAZ: PEDIATRIC CLINICAL TRIAL UNIT (UCICEC) FACILITIES 8 beds 2 simultaneous admissions phase I. Personnel trained in Advance Life Support 8
9 LA PAZ: PEDIATRIC CLINICAL TRIAL UNIT (UCICEC) PERSONNEL UCICEC Permanent: 6 Non-permanent: 7 Partial time: 15 PEDIATRIC UNITS 20 Physicians in the dayshift, 10 of them also make guards (24-hour shift) 15 Nurses of pediatric hospitalization plants accustomed to the management of children, distributed among all shifts and all specialties. At least 1 nurse per specialty and shift. In morning shifts, 6 nurses participating in CT are also added from the external consultations of the pediatric specialties 9
10 LA PAZ: PEDIATRIC CLINICAL TRIAL UNIT (UCICEC) SUBJECTS & PATIENTS POPULATION Healthy volunteers Patients Adopters, inmigrants and refugees Tertiary reference center of all especialities. PHARMACODYNAMIC / PHARMACOKINETIC 14 CT in Phase 1 with evaluation PK/PD 7 CT Phase I-II in which blood samples are processed for cell immunity 10
11 LA PAZ: PEDIATRIC CLINICAL TRIAL UNIT (UCICEC) EXPERIENCE (5 LAST YEARS) Phase Number of studies I II III IV Observational Pharmaceutical company Independent group Individual research 11
12 AREAS & RESEARCH GROUPS
13 PEDIATRIC RESEARCH GROUPS INFECCIOUS DISEASES & IMMUNITY AREA PATOLOGÍA INFECCIOSA RESPIRATORIA, SISTÉMICA Y NEUROLÓGICA EN LA INFANCIA, Y RESPUESTA INMUNOLÓGICA DEL HUÉSPED Cristina Calvo Rey INFECCIONES SISTÉMICAS EN PEDIATRÍA; VIH, TUBERCULOSIS, PATOLOGÍA IMPORTADA Y ENFERMEDADES EMERGENTES María José Mellado Peña INVESTIGACIÓN TRASLACIONAL EN CÁNCER INFANTIL, TRASPLANTE HEMATOPOYÉTICO Y TERAPIA CELULAR Antonio Pérez Martínez 13
14 PEDIATRIC RESEARCH GROUPS PATHOLOGY OF LARGE SYSTEMS NEONATOLOGÍA Adelina Pellicer HEPATOLOGÍA MOLECULAR Paloma Jara Vega CIRUGÍA DE MALFORMACIONES CONGÉNITAS Leopoldo Martínez Martínez TRASPLANTES Francisco Hernandez Oliveros SURGERY, TRANSPLANTATION AND HEALTH TECHNOLOGY 14
15 Networks
16 European Reference Network in Pediatric Transplantation
17 TRASPLANTCHILD Health Care Improvement Identify areas of research and innovation Facilitating patient empowerment Improvement of the results of the procedures and the quality of life (clinical guidelines). Spread Knowledge 17
18 IDIPAZ FOUNDATION EXECUTIVE COMMITTEE GENERAL COORDINATOR Federico Martinón CLINICAL LEADERS OF CONSOLIDATED/THEMATIC CENTRES HOSPITAL UNIVERSITARIO 12 DE OCTUBRE Daniel Blázquez HOSPITAL UNIVERSITARIO Y POLITÉCNICO LA FE Eduardo Montesinos HOSPITAL INFANTIL UNIVERSITARIO NIÑO JESÚS Lucas Moreno HOSPITAL UNIVERSITARIO VALL D HEBRON Carlos Rodrigo HOSPITAL UNIVERSITARIO LA PAZ José Luis Narro MANAGEMENT LEADERS HOSPITAL SANT JOAN DE DÉU Joana Claverol HOSPITAL CLÍNICO UNIVERSITARIO DE SANTIAGO DE COMPOSTELA María Gómez Reino RED DE INVESTIGACIÓN TRALACIONAL EN INFECTOLOGÍA PEDIÁTRICA (RITIP) Cristina Calvo THEMATIC NETWORKS RED DE SALUD MATERNO INFANTIL Y DESARROLLO (SAMID) Fernando Cabañas 18
19 SAMID NETWORK RETICS financiada por el PN I+D+I , ISCIII - Subdirección General de Evaluación y Fomento de la Investigación y el Fondo Europeo de Desarrollo Regional (FEDER), ref. RD16/0022. Maximo Vento & Fernando Cabañas 19
20 SAMID NETWORK Fernando Cabañas Leopoldo Martínez 20
21 RITIP NETWORK Traslational Research Network in Pediatric Infectious Diseases Cristina Calvo & Federico Martinón 21
22 RITIP NETWORK Cristina Calvo Mª José Mellado 22
23 TEDDY network Task-force in Europe for Drug Development for the Young Mª José Mellado 23
24 TEDDY network Task-force in Europe for Drug Development for the Young 24
25 THANK YOU Working in Group Working in Network Working in Europe 25
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