Clinical & Rehabilitative Medicine Research Program
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1 Clinical & Rehabilitative Medicine Research Program UNCLASSIFIED Dr. Tony Gover, Civilian Deputy Director Clinical & Rehabilitative Medicine Research Program US Army Medical Research & Materiel Command UNCLASSIFIED 1
2 Purpose To increase understanding of the Clinical & Rehabilitative Medicine Research Program (CRMRP), the CRMRP Program Areas, and the Program Areas objectives. Outline CRMRP Overview CRMRP Program Areas Neuromusculoskeletal Injury Pain Management Regenerative Medicine Sensory Systems The views expressed in this presentation are those of the author(s) and may not reflect the official policy or position of the Department of the Army, Department of Defense, or the U.S. Government. UNCLASSIFIED 2
3 CRMRP Overview Mission To implement long-term strategies to develop knowledge and materiel products to reconstruct, rehabilitate, and provide definitive care for injured Service Members. The ultimate goal is to return the Service Member to duty and restore their quality of life. UNCLASSIFIED 3
4 CRMRP Program Areas Pain Management: Management of pain ranging from the point of injury to chronic pain management Regenerative Medicine: Extremity and craniomaxillofacial injuries, burns and scarless wound healing, hand and face transplants, genitourinary lower abdominal reconstruction Neuromusculoskeletal Injury: Prosthetics, orthotics, and orthopedic injury rehabilitation Sensory Systems: Visual, auditory, and vestibular dysfunction associated with traumatic injury UNCLASSIFIED 4
5 Neuromusculoskeletal Injury Neuromusculoskeletal Injury includes research (applied science to advanced development) in rehabilitation/reintegration in the areas of amputation/prosthetics, limb trauma/orthotics and other neuromusculoskeletal injury. Purpose: Maximized rehabilitation after service-related neuromusculoskeletal injuries. Neuromusculoskeletal Injury Objectives: 1. Development/evaluation/validation of new and existing reintegration interventions 2. Evaluation of afferent/efferent systems toward enhanced and intuitive control of prosthetics 3. Identifying biomarkers of secondary health deficits 4. Evaluation/validation of dose, timing, frequency, and duration of rehabilitation UNCLASSIFIED 5
6 Pain Management Pain Management includes research (applied science to advanced development) for the management of pain ranging from point of injury to chronic pain management. Purpose: Provide products and information solutions for the diagnosis and alleviation of battlefield, acute and chronic pain and sequela. Pain Management Objectives: 1. Investigate battlefield pain management strategies 2. Investigate precision medicine/ personalized pain management strategies 3. Investigate treatment approaches for chronic pain in complex patients 4. Validate non-pharmacological approaches to pain management UNCLASSIFIED 6
7 Regenerative Medicine Regenerative Medicine includes research (applied science to advanced development) in repair, reconstruction or regeneration of tissue lost or damaged from traumatic injury in the areas of: extremity injury, craniomaxillofacial injury, burns/scarring, composite tissue transplantation, and genitourinary/lower abdomen reconstruction. Purpose: Restoration of form and function to injured bone and soft tissues. Regenerative Medicine Objectives: 1. Identify/evaluate technologies that increase speed and completeness of healing following volumetric muscle loss, peripheral nerve and vascular injury 2. Identify/evaluate technologies to generate and integrate functional composite tissues 3. Identify/evaluate technologies that increase speed and completeness of skin healing following burn injuries UNCLASSIFIED 7
8 Sensory Systems Sensory Systems includes research (applied science to advanced development) focused on understanding the mechanisms of and developing treatment strategies for traumatic injuries resulting in visual, auditory, and vestibular dysfunction. Purpose: Restore and rehabilitate sensory systems (vision, hearing and balance) following traumatic injury. Sensory System Objectives: 1. Identify/evaluate optimal corneal treatment options 2. Identify/evaluate regenerative and pharmaceutical therapies for restoring and treating optical nerve injuries 3. Quantify impacts of TBI on multisensory integration and balance to aid diagnosis and treatment post-injury UNCLASSIFIED 8
9 Questions? For additional questions after the conclusion of the conference, send an message to UNCLASSIFIED 9
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