Evaluation of 4 artemisinin-based combinations for treating uncomplicated malaria in African children Preliminary results

A Head-to-Head Comparison of Four Artemisinin-Based Combinations for Treating Uncomplicated Malaria in African Children: A Randomized Trial

A Head-to-Head Comparison of Four Artemisinin-Based Combinations for Treating Uncomplicated Malaria in African Children: A Randomized Trial The Four Artemisinin-Based Combinations (4ABC) Study Group* "

Clinical Analysis Report For Study Sample Study

Clinical Analysis Report For Study Sample Study Automated report generated by WWARN May 9, 2014 Falciparum class org.wwarn.csr.clinicalstudyreport Version 1.020140508-1558 1 Contents 1 Executive Summary

Status of RTS,S/AS01 malaria vaccine candidate

Status of RTS,S/AS01 malaria vaccine candidate Multi-center RTS,S malaria vaccine efficacy trial Phase 3, randomized, controlled, double-blind trial conducted in 11 centers in 7 African countries 15,460

Sponsor / Company: Sanofi Drug substance(s): artesunate plus amodiaquine Title of the study:

These results are supplied for informational purposes only. Prescribing decisions should be made based on the approved package insert in the country of prescription. Sponsor / Company: Sanofi Drug substance(s):

Supplementary figures

Weight, kg Lumefantrine concentration μg/ml Supplementary figures 8 7 6 5 4 3 2 model data 1 0 0 5 10 15 Days Supplementary Figure 1. Plasma lumefantrine concentrations in African children [1] and model-fitted

Sponsor / Company: Sanofi Drug substance(s): SSR103371

These results are supplied for informational purposes only. Prescribing decisions should be made based on the approved package insert in the country of prescription. Sponsor / Company: Sanofi Drug substance(s):

Statistical Analysis Plan (SAP)

Statistical Analysis Plan (SAP) Comparison of artemether-lumefantrine and chloroquine with and without primaquine for the treatment of Plasmodium vivax in Ethiopia: a randomized controlled trial Contents

IMPLEMENTING RISK MANAGEMENT PLANS IN AFRICA: THE ASAQ Winthrop RISK MANAGEMENT PLAN. François Bompart Access to Medicines - Sanofi

IMPLEMENTING RISK MANAGEMENT PLANS IN AFRICA: THE ASAQ Winthrop RISK MANAGEMENT PLAN François Bompart Access to Medicines - Sanofi Artesunate Amodiaquine Winthrop (ASAQ Winthrop ) Infant (

Partnerships in action

From field experience to the discovery of antimalarials: Partnerships in action Chairman: Wilfred Mbacham, Biotechnologies Centre, University of Yaounde I, Cameroon Co-chairmen: Timothy Wells, Chief Scientific

A Simple Dose Regimen of Artesunate and Amodiaquine Based on Arm Span- or Age Range for Childhood Falciparum Malaria: A Preliminary Evaluation

JOURNAL OF TROPICAL PEDIATRICS, VOL. 58, NO. 4, 2012 A Simple Dose Regimen of Artesunate and Amodiaquine Based on Arm Span- or Age Range for Childhood Falciparum Malaria: A Preliminary Evaluation by Akintunde

EDCTP Portfolio Evaluating clinical trials in Africa

EDCTP Portfolio Evaluating clinical trials in Africa - 1 - 1.1 Munguambe... - 5-1.2 Pare Toe... - 7-1.3 Asante... - 9 - - 2 - JCMS 2010 call for Evaluating the Impact of Clinical Trials in Africa supported

Jaderson Lima, MD On behalf of François Bompart, MD

Challenges and Successes of the FACT Project through Innovative Partnerships for the Development of Artesunate Combination Therapies for Malaria 5º. ENIFarMed São Paulo Brazil August 2011 Public-private

Risk associated with asymptomatic parasitaemia occurring post-antimalarial treatment

Tropical Medicine and International Health doi:10.1111/j.1365-3156.2007.01977.x volume 13 no 1 pp 83 90 january 2008 Risk associated with asymptomatic parasitaemia occurring post-antimalarial treatment

Downloaded from:

Abreha, T; Alemayehu, B; Assefa, A; Awab, GR; Baird, JK; Bezabih, B; Cheah, PY; Day, NP; Devine, A; Dorda, M; Dondorp, AM; Girma, S; Hien, TT; Jima, D; Kassa, M; Kebende, A; Khu, NH; Leslie, T; Ley, B;

ATAQ EASY. Coarsucam versus Coartem for uncomplicated Plasmodium falciparum malaria

ATAQ EASY versus Coartem for uncomplicated Plasmodium falciparum malaria A multinational, randomized study comparing the tolerability and efficacy Randrianarivelojosia M,, Randrianasolo L, Ratsimbasoa

Summary. keywords in vivo efficacy, sulphadoxine pyrimethamine, chloroquine, amodiaquine, combination therapy, falciparum malaria, Uganda

Tropical Medicine and International Health volume 9 no 2 pp 222 229 february 2004 Efficacy of sulphadoxine pyrimethamine alone or combined with amodiaquine or chloroquine for the treatment of uncomplicated

Malaria Journal This Provisional PDF corresponds to the article as it appeared upon acceptance. Fully formatted PDF and full text (HTML) versions will be made available soon. Efficacy of artesunate-amodiaquine

Akintunde Sowunmi 1,2,5*, Kazeem Akano 1, Adejumoke I. Ayede 3, Godwin Ntadom 4, Temitope Aderoyeje 5, Elsie O. Adewoye 6 and Bayo Fatunmbi 7

Sowunmi et al. BMC Infectious Diseases (2016) 16:240 DOI 10.1186/s12879-016-1565-4 RESEARCH ARTICLE Clinical illness and outcomes in Nigerian children with late-appearing anaemia after artemisinin-based

Artesunate plus pyronaridine for treating uncomplicated Plasmodium falciparum malaria (Review)

Artesunate plus pyronaridine for treating uncomplicated Plasmodium falciparum malaria (Review) Bukirwa H, Unnikrishnan B, Kramer CV, Sinclair D, Nair S, Tharyan P This is a reprint of a Cochrane review,

Clinical Study Therapeutic Efficacy of Artemether-Lumefantrine for the Treatment of Uncomplicated Plasmodium falciparum Malaria in Northern Ethiopia

Malaria Research and Treatment Volume 2012, Article ID 548710, 6 pages doi:10.1155/2012/548710 Clinical Study Therapeutic Efficacy of Artemether-Lumefantrine for the Treatment of Uncomplicated Plasmodium

Malaria in pregnancy programmes: challenges and priorities in antimalarial drug development for African pregnant women

7 th MIM Pan African Malaria Conference 15-20 April 2018 Dakar, Senegal The power of sharing science EDCTP session on Malaria in pregnancy programmes: challenges and priorities in antimalarial drug development

Abstract. Introduction

MSF Field Research Dihydroartemisinin-piperaquine and artemether-lumefantrine for treating uncomplicated malaria in African children: a randomised, non-inferiority trial Item type Authors Citation DOI

H. Tinto 1,2, E. B. Zoungrana 1, S. O. Coulibaly 1, J. B. Ouedraogo 1,2, M. Traoré 1,2, T. R. Guiguemde 1, E. Van Marck 3 and U.

Tropical Medicine and International Health volume7no11pp925 930november2002 Chloroquine and sulphadoxine-pyrimethamine efficacy for uncomplicated malaria treatment and haematological recovery in children

Articles. The West African Network for Clinical Trials of Antimalarial Drugs (WANECAM)*

Pyronaridine artesunate or dihydroartemisinin piperaquine versus current first-line therapies for repeated of uncomplicated malaria: a randomised, multicentre, open-label, longitudinal, controlled, phase

Checchi, F; Piola, P; Kosack, C; Ardizzoni, E; Klarkowski, D; Kwezi, E; Priotto, G; Balkan, S; Bakyaita, N; Brockman, A; Guthmann, J P

MSF Field Research Antimalarial efficacy of sulfadoxine-pyrimethamine, amodiaquine and a combination of chloroquine plus sulfadoxinepyrimethamine in Bundi Bugyo, western Uganda. Authors Citation DOI Publisher

Safe and efficacious artemisinin-based combination treatments for African pregnant women with malaria: a multicentre randomized control trial

Nambozi et al. Reproductive Health 2015, 12:5 STUDY PROTOCOL Open Access Safe and efficacious artemisinin-based combination treatments for African pregnant women with malaria: a multicentre randomized

Dihydroartemisinin/Piperaquine Application for Inclusion in the 17 th WHO Model List of Essential Medicines 15 November 2010

APPLICATION FOR INCLUSION OF DIHYDROARTEMISININ PLUS PIPERAQUINE (DHA/PPQ) FIXED DOSE COMBINATION TABLETS IN THE 17 th EDITION OF THE WHO MODEL LISTS OF ESSENTIAL MEDICINES Page 1 TABLE OF CONTENTS 1.

JTEG s Summary of RTS,S/ AS01 Clinical Trial Data

JTEG s Summary of RTS,S/ AS01 Clinical Trial Data Peter Smith On behalf of the Joint Technical Expert Group (JTEG) based on Cohen et al 2010 RTS,S/AS01 Malaria Vaccine l Based on large segment of P. falciparum

La terapia della malaria

Verona, 15 marzo 2018 La terapia della malaria Zeno Bisoffi Ritardo diagnostico e carica parassitaria Turista (Kenya), 50 a, febbre da 3 h Turista (G. Bissau), 36 a, febbre da 8 gg Ritardo diagnostico

Malaria Control. Umberto D Alessandro

Malaria Control Umberto D Alessandro Zanzibar - hospitalizations et malaria deaths 1999-2008 2 The Gambia - slide positivity rates 2003-2009 Under-5 mortality rate (per 1,000 live births) 300 250 200 150

The global context for financing delivery innovations in fever case management and malaria treatment. Ramanan Laxminarayan

The global context for financing delivery innovations in fever case management and malaria treatment Ramanan Laxminarayan Changed environment 1. Greater challenges in continued funding for global health

ACTs in East Africa REALITY CHECK. Nathan Mulure MD Novartis Pharma

ACTs in East Africa REALITY CHECK Nathan Mulure MD Novartis Pharma 1 Agenda Introduction and background Drug resistance to antimalarials Policy change Antimalarial market Challenges 2 Malaria Burden 34,000

Low Efficacy of Vocamine (MMH8, Pediatric Formulation) in the Treatment of Uncomplicated Plasmodium falciparum Malaria

8 The Open Tropical Medicine Journal, 2009, 2, 8-12 Low Efficacy of Vocamine (MMH8, Pediatric Formulation) in the Treatment of Uncomplicated Plasmodium falciparum Malaria Open Access Didier Ménard 1,*,

Early rising asexual parasitaemia in Nigerian children following a first dose of artemisinin-based combination treatments of falciparum malaria

Sowunmi et al. BMC Infectious Diseases (2017) 17:110 DOI 10.1186/s12879-016-2173-z RESEARCH ARTICLE Early rising asexual parasitaemia in Nigerian children following a first dose of artemisinin-based combination

METHODS FOR SURVEILLANCE OF ANTIMALARIAL DRUG EFFICACY ISBN

METHODS FOR SURVEILLANCE OF ANTIMALARIAL DRUG EFFICACY METHODS FOR SURVEILLANCE OF ANTIMALARIAL DRUG EFFICACY ISBN 978 92 4 159753 1 METHODS FOR SURVEILLANCE OF ANTIMALARIAL DRUG EFFICACY WHO Library Cataloguing-in-Publication

Development of a Malaria Vaccine for Sub-Saharan African Children December 3, 2009 Lode Schuerman

Development of a Malaria Vaccine for Sub-Saharan African Children December 3, 2009 Lode Schuerman Copyright John-Michael Maas, Darby Communications Agenda Malaria Disease burden Prevention and vaccine

Harry Tagbor 1, Matthew Cairns 2, Emmanuel Nakwa 1, Edmund Browne 1, Badu Sarkodie 3, Helen Counihan 4, Sylvia Meek 4 and Daniel Chandramohan 2

Tropical Medicine and International Health doi:10.1111/j.1365-3156.2010.02699.x volume 16 no 3 pp 280 289 march 2011 The clinical impact of combining intermittent preventive treatment with home management

APPLICATION FOR REVISION AND INCLUSION OF MALARIA MEDICINES IN WHO MODEL LIST OF ESSENTIAL MEDICINES

APPLICATION FOR REVISION AND INCLUSION OF MALARIA MEDICINES IN WHO MODEL LIST OF ESSENTIAL MEDICINES The objective of this application is to assure compatibility between the WHO Model list of essential

Clinical Study Clinical Efficacy of Artemether-Lumefantrine in Congolese Children with Acute Uncomplicated Falciparum Malaria in Brazzaville

Malaria Research and Treatment Volume 2012, Article ID 749479, 5 pages doi:10.1155/2012/749479 Clinical Study Clinical Efficacy of Artemether-Lumefantrine in Congolese Children with Acute Uncomplicated

Copyright The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND license.

Comparison of artesunate mefloquine and artemether lumefantrine fixed-dose combinations for treatment of uncomplicated Plasmodium falciparum malaria in children younger than 5 years in sub-saharan Africa:

Dihydroartemisinin-piperaquine for treating uncomplicated Plasmodium falciparum malaria (Review)

Dihydroartemisinin-piperaquine for treating uncomplicated Plasmodium falciparum malaria (Review) Zani B, Gathu M, Donegan S, Olliaro PL, Sinclair D This is a reprint of a Cochrane review, prepared and

EDCTP Executive diseases of poverty in Africa. It is certainly a very vital platform for networking,

Vol 3, No 1 EDCTP newsletter January 2008 Executive Director s Note News about Calls and Grants Calls open for application - HIV Treatment - HIV Microbicides - HIV Vaccines Funded projects TB treatment

Antimalarial drug resistance

Antimalarial drug resistance Md Mushfiqur Rahman*, Leonard Ortega**, R M Rastogi* and Krongthong Thimasarn* Abstract Antimalarial drug resistance is of great concern in the WHO South-East Asia (SEA) Region.

GRADE tables to assist guideline development and recommendations. Plain Language Summary of Results

Seasonal Malaria Chemoprevention (formally known as Intermittent Preventive Treatment in children) for preventing malaria morbidity in children aged less than 5 years living in areas of marked seasonal

Study No.: Title: Rationale: Phase: Study Period: Study Design: Centers: Indication: Treatment: Objective: Primary Outcome/Efficacy Variable:

The study listed may include approved and non-approved uses, formulations or treatment regimens. The results reported in any single study may not reflect the overall results obtained on studies of a product.

Changes in proximate determinants of fertility in sub-saharan Africa

Changes in proximate determinants of fertility in sub-saharan Africa Kazuyo Machiyama, Andy Sloggett, John Cleland London School of Hygiene & Tropical Medicine Quality and comparability of demographic

Schramm et al. Malaria Journal 2013, 12:251

Schramm et al. Malaria Journal 2013, 12:251 RESEARCH Open Access Efficacy of artesunate-amodiaquine and artemether-lumefantrine fixed-dose combinations for the treatment of uncomplicated Plasmodium falciparum

Stakeholders meeting on Malaria

Plans and progress towards EDCTP2 Stakeholders meeting on Malaria 19 September 2013 Austrian Ministry of Science and Research First district of Vienna, Freyung 3, Vienna, Austria. Michael Makanga, MD PhD.

European & Developing Countries Clinical Trials Partnership. project portfolio. Networking grants

European & Developing Countries Clinical Trials Partnership project portfolio Networking grants 1 Networking grants... 2 1.1.1 Marleen Temmerman... 4 1.1.2 Bob Colebunders... 5 1.1.3 Daniel Kyabayinze...

Authors Depoortere, E; Guthmann, J P; Pressé, J; Sipilanyambe, N; Nkandu, E; Balkan, S; de Pécoulas, P E; Legros, D /j

MSF Field Research Efficacy and effectiveness of the combination of sulfadoxine/pyrimethamine and a 3-day course of artesunate for the treatment of uncomplicated falciparum malaria in a refugee settlement

Stephan Duparc 1*, Isabelle Borghini-Fuhrer 1, J Carl Craft 1,2, Sarah Arbe-Barnes 3, Robert M Miller 3, Chang-Sik Shin 4 and Lawrence Fleckenstein 5

Duparc et al. Malaria Journal 213, 12:7 http://www.malariajournal.com/content/12/1/7 RESEARCH Open Access Safety and efficacy of pyronaridine-artesunate in uncomplicated acute malaria: an integrated analysis

MALARIA IS ONE OF THE

ORIGINAL CONTRIBUTION Combination Therapy for Uncomplicated Falciparum Malaria in Ugandan Children A Randomized Trial Grant Dorsey, MD, PhD Sarah Staedke, MD Tamara D. Clark, MPH Denise Njama-Meya, MB

14th Stakeholders Meeting

14th Stakeholders Meeting Steady progress towards malaria elimination: Interventions for today and tomorrow Denpasar, Bali 11 12 October 2017 David Hughes, Novartis 12th October 2017 Defeating Malaria

Against intervention No recommendation Strong Conditional Conditional Strong. For intervention. High Moderate Low Very low

Draft recommendation: Consider using MDA as an additional tool for the elimination of malaria in low prevalence island or nonisland settings where the risk of imported malaria is low Balance of desirable

The Challenge of Malaria

The Challenge of Malaria Prof. Awa-Marie Coll-Seck Executive Director of RBM Partnership Donors Forum (co-organized by MMV & CRESIB) Barcelona, 15 March 2010 A DECADE OF ROLLING BACK MALARIA: WHERE ARE

Artesunate Mefloquine (AsMq)

Artesunate Mefloquine (AsMq) Introduction AsMq in Rakhine in 1996 AsMq FDC compared to other ACTs AZG (MSF-Holland) malaria activities in Western Myanmar 9 townships 25 DoH clinics with AZG support (area

MMV s Access & Product Management Strategy

MMV s Access & Product Management Strategy Siem Reap, Cambodia 24-26 February 2015 George Jagoe, EVP, Access & Product Mgmt Defeating Malaria Together OUR MISSION to reduce the burden of malaria in disease-endemic

Chemoprophylaxis and intermittent treatment for preventing malaria in children (Review)

Chemoprophylaxis and intermittent treatment for preventing malaria in children (Review) Meremikwu MM, Donegan S, Esu E This is a reprint of a Cochrane review, prepared and maintained by The Cochrane Collaboration

HAT DNDi program progress and evolution in the path to elimination. Dr Antoine Tarral. HAT Platform, Kampala October 2018

HAT DNDi program progress and evolution in the path to elimination Dr Antoine Tarral HAT Platform, Kampala October 2018 DNDi s Mission To develop new drugs or new formulations of existing drugs for people

Phenotyping Plasmodium vivax in Indonesia using Standard Chloroquine Therapy. Puji Budi Setia Asih. Eijkman Institute for Molecular Biology

Phenotyping Plasmodium vivax in Indonesia using Standard Chloroquine Therapy Puji Budi Setia Asih Eijkman Institute for Molecular Biology Background Plasmodium vivax threatens 2.6 billion people with a

38 Current Concepts in

38 Current Concepts in Management of Falciparum Malaria Abstract: Artemisinin based Combination Therapy (ACT) is the preferred agent to treat drug resistance uncomplicated Plasmodium Falciparum (PF) Malaria.

Abstract. Correspondence to: Umberto D Alessandro

College of Medicine Silver Jubilee Special Issue Artemisinin-based treatments in pregnant women with malaria 139 Research Article (New England Journal of Medicine) Four artemisinin-based treatments in

Abstract. Van Malderen et al. Malaria Journal 2012, 11:139

Van Malderen et al. Malaria Journal 2012, 11:139 RESEARCH Open Access Glucose-6-phosphate dehydrogenase deficiency, chlorproguanil-dapsone with artesunate and post-treatment haemolysis in African children

Fighting Harder and Smarter Against Malaria. Dr.Bernard Nahlen Deputy US Global Malaria Coordinator University of Georgia, February 23, 2010

Fighting Harder and Smarter Against Malaria Dr.Bernard Nahlen Deputy US Global Malaria Coordinator University of Georgia, February 23, 2010 Outline Burden of malaria Global support for rolling back malaria

Downloaded from:

Kapisi, J; Bigira, V; Clark, T; Kinara, S; Mwangwa, F; Achan, J; Kamya, M; Soremekun, S; Dorsey, G (2015) Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated malaria in the

PROGRESS REPORT ON CHILD SURVIVAL: A STRATEGY FOR THE AFRICAN REGION. Information Document CONTENTS

29 June 2009 REGIONAL COMMITTEE FOR AFRICA ORIGINAL: ENGLISH Fifty-ninth session Kigali, Republic of Rwanda, 31 August 4 September 2009 Provisional agenda item 9.2 PROGRESS REPORT ON CHILD SURVIVAL: A

Downloaded from:

Konat, AT; Yaro, JB; Oudraogo, AZ; Diarra, A; Gansan, A; Soulama, I; Kangoy, DT; Kabor, Y; Oudraogo, E; Oudraogo, A; Tiono, AB; Oudraogo, IN; Chandramohan, D; Cousens, S; Milligan, PJ; Sirima, SB; Greenwood,

Summary World Malaria Report 2010

Summary The summarizes information received from 106 malaria-endemic countries and other partners and updates the analyses presented in the 2009 Report. It highlights continued progress made towards meeting

New Partnerships The Development of ASMQ - FDC

New Partnerships The Development of ASMQ - FDC Jean-René Kiechel Senior Product Manager DNDi January 2011 1 ACTs: World Health Organization Treatment Guidelines (2006) In order to fight resistance: 1.

GSK Medicine Study Number: Title: Rationale Phase: Study Period: Study Design: Centres: Indication: Treatment: Objectives:

The study listed may include approved and nonapproved uses, formulations or treatment regimens. The results reported in any single study may not reflect the overall results obtained on studies of a product.

WHO/GMP TECHNICAL EXPERT GROUP ON PREVENTIVE CHEMOTHERAPY, Geneva 4-6 May 2011

WHO/GMP TECHNICAL EXPERT GROUP ON PREVENTIVE CHEMOTHERAPY, Geneva 4-6 May 2011 Background Report of the Technical consultation on Seasonal Malaria Chemoprevention (SMC) / Chimio-prévention saisonnière

Malaria case management and Diagnostics under artemether-lumefantrine treatment policy in Uganda

Malaria case management and Diagnostics under artemether-lumefantrine treatment policy in Uganda Dr Nankabirwa Joaniter (MBchB, MSc CEB) Malaria Consortium, Uganda National Malaria Control Programme, MoH,

BRIEFING ON RTS,S/AS01 MALARIA VACCINE FOR THE SEPTEMBER 2012 MEETING OF MPAC

BRIEFING ON RTS,S/AS01 MALARIA VACCINE FOR THE SEPTEMBER 2012 MEETING OF MPAC Introduction Date: 12 August 2012. Author: WHO Secretariat with input from JTEG Chair The most advanced vaccine candidate against

THE EFFECTS OF HAEMOGLOBINOPATHIES AND G6PD DEFICIENCY ON MALARIA AMONG CHILDREN OF THE KINTAMPO NORTH MUNICIPALITY OF GHANA

THE EFFECTS OF HAEMOGLOBINOPATHIES AND G6PD DEFICIENCY ON MALARIA AMONG CHILDREN OF THE KINTAMPO NORTH MUNICIPALITY OF GHANA Presenter: Amoako Nicholas 1 Supervisors: Dr. Kwaku Poku Asante 1, Dr. Bimi

Bisoffi, Zeno; Sirima, Bienvenu Sodiomon; Angheben, Andrea; Lodesani, Claudia; Gobbi, Federico; Tinto, Halidou; Van den Ende, Jef

MSF Field Research Rapid malaria diagnostic tests vs. clinical management of malaria in rural Burkina Faso: safety and effect on clinical decisions. A randomized trial Item type Authors Article Bisoffi,

Effect of diagnostic testing on medicines used by febrile children less than five years in 12 malariaendemic African countries: a mixed-methods study

Johansson et al. Malaria Journal (2015) 14:194 DOI 10.1186/s12936-015-0709-0 RESEARCH Open Access Effect of diagnostic testing on medicines used by febrile children less than five years in 12 malariaendemic

Common EQA Mistakes - A provider Perspective. Experience from East African Regional External Quality Assessment Scheme (EA-REQAS)

Common EQA Mistakes - A provider Perspective Experience from East African Regional External Quality Assessment Scheme (EA-REQAS) Overview of Amref Health Africa Leading health development INGO in Africa

Clinical Drug Trials

Clinical Drug Trials Drug resistance to chloroquine in P. falciparum was reported in India for the first time from Assam in 1973. Since then the foci of resistance have spread to many more states all over

REPORT OF THE TECHNICAL CONSULTATION BACKGROUND

Defining and validating a measure of parasite resistance to sulfadoxinepyrimethamine (SP) that would be indicative of the protective efficacy of SP for intermittent preventive treatment in infancy (SP-IPTi)

Malaria Journal. Open Access RESEARCH

DOI 10.1186/s12936-016-1381-8 Malaria Journal RESEARCH Open Access Therapeutic efficacy trial of artemisinin based combination therapy for the treatment of uncomplicated malaria and investigation of mutations

Therapeutic efficacy and artemisinin resistance in northern Myanmar: evidence from in vivo and molecular marker studies

DOI 10.1186/s12936-017-1775-2 Malaria Journal RESEARCH Open Access Therapeutic efficacy and artemisinin resistance in northern Myanmar: evidence from in vivo and molecular marker studies Moe Kyaw Myint

Nr. 53. September 2006 INSTITUT FÜR MEDIZINISCHE BIOMETRIE UND INFORMATIK RUPRECHT-KARLS-UNIVERSITÄT HEIDELBERG

FORSCHUNGSBERICHTE DER ABTEILUNG MEDIZINISCHE BIOMETRIE, UNIVERSITÄT HEIDELBERG Nr. 53 Safety and efficacy of the combination of chloroquine and methylene blue in the treatment of uncomplicated falciparum

Is there Artemisinin Resistance in Western Cambodia?

Is there Artemisinin Resistance in Western Cambodia? Preliminary results, February 2008 Arjen Dondorp on behalf of the Task Force on Antimalarial Drug Resistance in Cambodia S769N PfATPase6 mutation Artemether

Downloaded from:

Myrick, A; Leemann, E; Dokomajilar, C; Hopkins, H; Dorsey, G; Kamya, MR; Rosenthal, PJ (2006) Short report: Dynamics of Plasmodium falciparum malaria after sub-optimal therapy in Uganda. The American journal

Monique A Dorkenoo 1,6*, Amy Barrette 2, Yao M Agbo 1,6, Hervé Bogreau 3, Séenam Kutoati 4, Yao K Sodahlon 5 and Kodjo Morgah 6

Dorkenoo et al. Malaria Journal 2012, 11:338 RESEARCH Open Access Surveillance of the efficacy of artemetherlumefantrine and artesunate-amodiaquine for the treatment of uncomplicated Plasmodium falciparum

Zwang et al. Malaria Journal 2012, 11:260

Zwang et al. Malaria Journal 2012, 11:260 RESEARCH Open Access Clinical tolerability of artesunate-amodiaquine versus comparator treatments for uncomplicated falciparum malaria: an individual-patient analysis

Lessons learned from the IeDEA West Africa Collaboration

Lessons learned from the IeDEA West Africa Collaboration François DABIS with the contribution of Didier Koumavi EKOUEVI INSERM U-897, Bordeaux, France, Programme PACCI, ANRS site, Abidjan, Côte d Ivoire

PDF hosted at the Radboud Repository of the Radboud University Nijmegen

PDF hosted at the Radboud Repository of the Radboud University Nijmegen The following full text is a publisher's version. For additional information about this publication click this link. http://hdl.handle.net/2066/172604

Authors van den Broek, I; Kitz, C; Al Attas, S; Libama, F; Balasegaram, M; Guthmann, J P

MSF Field Research Efficacy of three artemisinin combination therapies for the treatment of uncomplicated Plasmodium falciparum malaria in the Republic of Congo. Item type Article Authors van den Broek,

APPENDIX 1 DATA COLLECTION AND DISSEMINATION STEPS

APPENDIX 1 DATA COLLECTION AND DISSEMINATION STEPS 97 Country/ area APPENDIX 2a DRUG REGIMENS SEA REGION, 2001 (dosage for adults) : P. falciparum Lab confirmed Treatment failure Severe malaria Pregnancy

Efficacy of artesunate-amodiaquine for the treatment of acute uncomplicated falciparum malaria in southern Mauritania

Ouldabdallahi et al. Malaria Journal 2014, 13:496 RESEARCH Open Access Efficacy of artesunate-amodiaquine for the treatment of acute uncomplicated falciparum malaria in southern Mauritania Mohamed Ouldabdallahi

Correspondence should be addressed to Wilfred F. Mbacham;

Malaria Research and Treatment Volume 2013, Article ID 234683, 10 pages http://dx.doi.org/10.1155/2013/234683 Clinical Study Amodiaquine-Artesunate versus Artemether-Lumefantrine against Uncomplicated

Original Article. Ayan Basu 1, Santanu Saha 2, Subhasish Kamal Guha 3. Introduction. Abstract

32 Journal of The Association of Physicians of India Vol. 63 May 2015 Original Article Comparative Study of Effectiveness and Resistance Profile of Chloroquine and Sulfadoxine-Pyrimethamine in Uncomplicated

The authoritative academic voice on malaria research. Improving health worldwide

The authoritative academic voice on malaria research Improving health worldwide At the 6 th MIM Conference Durban, 6-11 October 2013 Where we work in Africa Economic evaluations of four prevention trials

Downloaded from:

Bukirwa, H; Yeka, A; Kamya, MR; Talisuna, A; Banek, K; Bakyaita, N; Rwakimari, JB; Rosenthal, PJ; Wabwire-Mangen, F; Dorsey, G; Staedke, SG (2006) Artemisinin combination therapies for treatment of uncomplicated

RTS,S malaria candidate vaccine reduces malaria by approximately one-third in African infants

Embargoed until Friday 9 th November, 0900 London (GMT); 1000 Brussels (CEST); 1100 Cape Town; 0400 (EST) New York RTS,S malaria candidate vaccine reduces malaria by approximately one-third in African

The PREGACT Study Group* abstract

The new england journal of medicine established in 1812 March 10, 2016 vol. 374 no. 10 Four Artemisinin-Based Treatments in African Pregnant Women with Malaria The PREGACT Study Group* abstract BACKGROUND

Artesunate combinations for treatment of malaria: meta-analysis

Articles Artesunate combinations for treatment of malaria: meta-analysis International Artemisinin Study Group* Summary Background Addition of artemisinin derivatives to existing drug regimens for malaria

MONITORING THE THERAPEUTIC EFFICACY OF ANTIMALARIALS AGAINST UNCOMPLICATED FALCIPARUM MALARIA IN THAILAND

SOUTHEAST ASIAN J TROP MED PUBLIC HEALTH MONITORING THE THERAPEUTIC EFFICACY OF ANTIMALARIALS AGAINST UNCOMPLICATED FALCIPARUM MALARIA IN THAILAND C Rojanawatsirivej 1, S Vijaykadga 1, I Amklad 1, P Wilairatna