1. はじめに. Key Words : Mini - Mental State Examination MMSE ; Folstein et al., Dementia Japan 27 : , 2013

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1 360 Dementia Japan 27 : , 2013 原著 要旨 HDS - R 14.7± ±7.6 p<0.001 MMSE 17.5± ±5.8 p<0.001 DBD 10.8± ±9.3 Vitality Index 6.9± ±1.9 GDS5 2.6± ±1.4 p< HDS - R 14 HDS - R Intensive rehabilitation for dementia in a Geriatric Health Services Facility (Roken) : Effect of intervention with 5 principles of Brain - activating rehabilitation Asako Sekine 1, Anna Nagashio 1, Kumiko Takahashi 1, Makoto Kato 1, Masamitsu Takatama 1, Haruyasu Yamaguchi 2 1) Youkouen Geriatric Health Services Facility, Geriatrics Research Institute Ootomo, Maebashi , Japan 2) Gunma University Graduate School of Health Sciences Showa, Maebashi , Japan Key Words : 1. はじめに HDS - R ; 1991 Mini - Mental State Examination MMSE ; Folstein et al.,

2 361 2, ; 2011 ; 2011 ; 2011 ; HDS - R 18, 19, 対象 方法 2.1. 対象 ; HDS - R MMSE ±9.3 ± 2.2. 方法 ; Yamaguchi et al., : 1) 快 : 2) コミュニケーション : 3) 褒める : 4) 役割 : 5) 失敗を防ぐ支援 : 2 3 HDS - R MMSE 30 BPSD Dementia Behavior Disturbance Scale DBD ; ; 1993 Vitality Index VI ; ; Toba et al., 2002 Geriatric Depression Scale 5 GDS5 ; 5 5 ; Hoyl et al., 1999 ; 2002 Table 1 Wilcoxon 122

3 362 Dementia Japan Vol. 27 No. 3 September 2013 a All 122 subjects Table 1. Effects of rehabilitation Scale Before intervention After intervention P value Cognitive function HDS - R 14.7± ±7.63 p<0.001 MMSE 17.5± ±5.81 p<0.001 BPSD DBD 10.8± ±9.31 p<0.001 Vitality VI 6.89± ±1.90 p<0.001 Depression GDS5 2.55± ±1.38 p<0.001 b Low HDS - R 14 or less group, 58 subjects Scale Before intervention After intervention P value Cognitive function HDS - R 8.83± ±4.61 p=0.005 MMSE 13.1± ±4.56 p<0.001 BPSD DBD 16.5± ±10.8 p<0.001 Vitality VI 6.31± ±2.03 p<0.001 Depression GDS5 2.38± ±1.35 p=0.005 c High HDS - R 15 or more group, 64 subjects Scale Before intervention After intervention P value Cognitive function HDS - R 20.1± ±5.16 p<0.001 MMSE 21.5± ±4.04 p=0.006 BPSD DBD 5.55± ±4.71 p=0.09 Vitality VI 7.42± ±1.72 p=0.02 Depression GDS5 2.70± ±1.39 p=0.003 Any scales showed significant improvement by comparison before and after the intensive rehabilitation for dementia with 5 principles of Brain - activating rehabilitation mean±s.d. ; Wilcoxon single - rank test. HDS - R HDS - R MMSE ± DBD ± VI GDS5 ± 結果 Table 1a HDS - R 14.7 ±6.48 ± 16.5±7.63 p<0.001 MMSE 17.5± ±5.81 p<0.001 BPSD DBD 10.8± ±9.31 p<0.001

4 363 HDS-R 40% 48% 11% MMSE DBD VI GDS5 34% 34% 46% 43% 56% 52% 36% 47% 11% 14% 18% 11% Improved Maintained Deteriorated 0% 20% 40% 60% 80% 100% Ratio Fig. 1. Ratio of subjects in improved, maintained and deteriorated groups, which were divided by the score of each scale. Ratio of the improved group was much higher than that of deteriorated group in any scales, showing the effects of intensive rehabilitation for dementia in Roken. HDS - R : Hasegawa dementia scale - revised ; MMSE : Mini - mental state examination ; DBD : Dementia disturbance scale ; VI : Vitality index ; GDS5 : Geriatric depression scale 5 item - version VI 6.89± ±1.90 p<0.001 GDS5 2.55± ±1.38 p<0.001 HDS - R 2 HDS - R Table 1b HDS - R DBD Table 1c DBD DBD DBD 12.8± ±3.79 p< Fig % 11 18% 考察 3 BPSD HDS - R MMSE HDS - R HDS - R 14 DBD HDS - R DBD 5.55 HDS - R /3 BPSD DBD HDS - R DBD

5 364 Dementia Japan Vol. 27 No. 3 September : BPSD DBD ; p= HDS - R ; p=0.001 VI ; p= GDS HDS - R HDS - R, MMSE ADL HDS - R BPSD COGNISTAT HDS - R 20 HDS - R MMSE Yamagami Yamaguchi et al., Henderlong et al., 2002 ; Dobkin et al., 2010 ; Sugawara et al., 2012 epub 2010 ; Yamaguchi et al., BPSD 122 文献 Dobkin BH, Plummer - D Amato P, Elashoff R, Lee J, SIRROWS Group 2010 International randomized clinical trial, stroke inpatient rehabilitation with reinforcement of walking speed SIRROWS, improves outcomes. Neurorehabil Neural

6 365 Repair 24 : : Folstein MF, Folstein SE, McHugh PR 1975 Mini - Mental State ; a practical method for grading the cognitive state of patients for the clinician. J Psychiat Res 12 : : Henderlong J, Lepper MR 2002 The effects of praise on children's intrinsic motivation : a review and synthesis. Psychol Bull 128 : Hoyl MT, Alessi CA, Harker JO, Josephson KR, Pietruszka FM, Koelfgen M, Mervis JR, Fitten LJ, Rubenstein LZ 1999 Development and testing of a five - item version of the Geriatric Depression Scale. J Am Geriatr Soc 47 : HDS - R 2 : GDS5 39 Suppl : DBD Demetia Behavior Disturbance Scale 30 : : Sugawara SK, Tanaka S, Okazaki S, Watanabe K, Sadato N 2012 Social rewards enhance offline improvements in motor skill. PLoS One 7 : e48174 doi : Epub Toba K, Nakai R, Akishita M, Iijima S, Nishinaga M, Mizoguchi T, Yamada S, Yumita K, Ouchi Y 2002 Vitality Index as a useful tool to assess elderly with dementia. Geriatr Gerontol Int 2 : : BPSD OT 22 : : Yamagami T, Oosawa M, Ito S, Yamaguchi H 2007 Effect of activity reminiscence therapy as brain - activating rehabilitation for elderly people with and without dementia. Psychogeriatrics 7 : Yamagami T, Takayama Y, Maki Y, Yamaguchi H 2012 A randomized controlled trial of brain - activating rehabilitation for elderly participants with dementia in residential care homes. Dement Geriatr Cogn Disord Extra 2 : pp Yamaguchi H, Maki Y, Yamagami T 2010 Overview of non - pharmacological intervention for dementia and principles of brain - activating rehabilitation. Psychogeriatrics 10 : Yamaguchi H, Maki Y, Takahashi K 2011 Rehabilitation for dementia using enjoyable video - sports games. Int Psychogeriatr 23 :

7 366 Dementia Japan Vol. 27 No. 3 September 2013 Intensive rehabilitation for dementia in a Geriatric Health Services Facility (Roken) : Effect of intervention with 5 principles of Brain - activating rehabilitation Asako Sekine 1, Anna Nagashio 1, Kumiko Takahashi 1, Makoto Kato 1, Masamitsu Takatama 1, Haruyasu Yamaguchi 2 1 Youkouen Geriatric Health Services Facility, Geriatrics Research Institute 2 Gunma University Graduate School of Health Sciences We have examined the effect of Intensive rehabilitation for dementia in a Geriatric Health Service Facility Roken. The subjects were 51 in - patients in the facility who met the inclusion criteria. Rehabilitation session was carried out individually, for 20 minutes, 3 times a week, for 3 months, with 5 principles of Brain - activation rehabilitation ; pleasant atmosphere, communication, role - playing, praising, error - less support. When outcome measures were compared between pre - and post - intervention, all of the measures of cognitive function HDS - R and MMSE, vitality Vitality index, depression GDS5, and behavioral and psychological symptoms DBD were significantly improved Wilcoxon signed - rank test. This result was duplicated in both groups, when subjects were divided into 2 groups according to the HDS - R score. Intensive rehabilitation for dementia for 3 months, which was associated with 5 principles of Brain - activating rehabilitation, was highly effective. We hope the rehabilitation spread throughout Japanese Geriatric Health Service Facilities Roken. Key Words : Geriatric health services facility Roken, dementia, rehabilitation, behavioral and psychological symptoms of dementia BPSD Address correspondence to Dr. Haruyasu Yamaguchi, Gunma University Graduate School of Health Sciences Showa, Maebashi , Japan