* Construction of a Frailty Index short (19 items) based on TOPICS-MDS questionnaire 2017 (baseline).
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1 * Encoding: UTF-8. ***************************************************************. * CR_Baseline_MDS2017_FrailtyIndex_19items. * Construction of a Frailty Index short (19 items) based on TOPICS-MDS questionnaire 2017 (baseline). * Specifically morbidities and ADL items were skipped from this Frailty Index, see Lutomski JE et al, Validation of a frailty index from the older persons and informal caregivers survey minimum data set.;. ** * Last updated: March 15, * Protocol of Searle et al "A standard procedure for creating a frailty index" BMC Geriatrics. * Convert values of included health deficits to indicate worsening condition - Range of 0 to 1. * ADVICE: run this syntax in pieces; running it all at once may create errors/problems. ***************************************************************. ***** Define deficits *****. *** Psych sub-scale ***. IF (T0_PW_NERV = 6) T0_FI_nerv=0. IF (T0_PW_NERV = 5) T0_FI_nerv=0.2. IF (T0_PW_NERV = 4) T0_FI_nerv=0.4. IF (T0_PW_NERV = 3) T0_FI_nerv=0.6. IF (T0_PW_NERV = 2) T0_FI_nerv=0.8. IF (T0_PW_NERV = 1) T0_FI_nerv=1. IF (T0_PW_BLUE = 6) T0_FI_blue=0.
2 IF (T0_PW_BLUE = 5) T0_FI_blue=0.2. IF (T0_PW_BLUE = 4) T0_FI_blue=0.4. IF (T0_PW_BLUE = 3) T0_FI_blue=0.6. IF (T0_PW_BLUE = 2) T0_FI_blue=0.8. IF (T0_PW_BLUE = 1) T0_FI_blue=1. IF (T0_PW_DOWN = 6) T0_FI_down=0. IF (T0_PW_DOWN = 5) T0_FI_down=0.2. IF (T0_PW_DOWN = 4) T0_FI_down=0.4. IF (T0_PW_DOWN = 3) T0_FI_down=0.6. IF (T0_PW_DOWN = 2) T0_FI_down=0.8. IF (T0_PW_DOWN = 1) T0_FI_down=1. IF (T0_PW_CALM = 6) T0_FI_calm=1. IF (T0_PW_CALM = 5) T0_FI_calm=0.8. IF (T0_PW_CALM = 4) T0_FI_calm=0.6. IF (T0_PW_CALM = 3) T0_FI_calm=0.4. IF (T0_PW_CALM = 2) T0_FI_calm=0.2. IF (T0_PW_CALM = 1) T0_FI_calm=0. IF (T0_PW_HAPPY = 6) T0_FI_happy=1. IF (T0_PW_HAPPY = 5) T0_FI_happy=0.8. IF (T0_PW_HAPPY = 4) T0_FI_happy=0.6. IF (T0_PW_HAPPY = 3) T0_FI_happy=0.4.
3 IF (T0_PW_HAPPY = 2) T0_FI_happy=0.2. IF (T0_PW_HAPPY = 1) T0_FI_happy=0. *** EQ-5D-5L ***. IF (T0_EQ5MO = 1) T0_FI_EQ_mob=0. IF (T0_EQ5MO = 2) T0_FI_EQ_mob=0.25. IF (T0_EQ5MO = 3) T0_FI_EQ_mob=0.5. IF (T0_EQ5MO = 4) T0_FI_EQ_mob=0.75. IF (T0_EQ5MO = 5) T0_FI_EQ_mob=1. IF (T0_EQ5SC = 1) T0_FI_EQ_selfcare=0. IF (T0_EQ5SC = 2) T0_FI_EQ_selfcare=0.25. IF (T0_EQ5SC = 3) T0_FI_EQ_selfcare=0.5. IF (T0_EQ5SC = 4) T0_FI_EQ_selfcare=0.75. IF (T0_EQ5SC = 5) T0_FI_EQ_selfcare=1. IF (T0_EQ5ACT= 1) T0_FI_EQ_act=0. IF (T0_EQ5ACT = 2) T0_FI_EQ_act=0.25. IF (T0_EQ5ACT = 3) T0_FI_EQ_act=0.5. IF (T0_EQ5ACT = 4) T0_FI_EQ_act=0.75. IF (T0_EQ5ACT = 5) T0_FI_EQ_act=1.
4 IF (T0_EQ5PAIN= 1) T0_FI_EQ_pain=0. IF (T0_EQ5PAIN = 2) T0_FI_EQ_pain=0.25. IF (T0_EQ5PAIN = 3) T0_FI_EQ_pain=0.5. IF (T0_EQ5PAIN = 4) T0_FI_EQ_pain=0.75. IF (T0_EQ5PAIN = 5) T0_FI_EQ_pain=1. IF (T0_EQ5ANX= 1) T0_FI_EQ_mood=0. IF (T0_EQ5ANX = 2) T0_FI_EQ_mood=0.25. IF (T0_EQ5ANX = 3) T0_FI_EQ_mood=0.5. IF (T0_EQ5ANX = 4) T0_FI_EQ_mood=0.75. IF (T0_EQ5ANX = 5) T0_FI_EQ_mood=1. *** Social functioning and self-reported health ***. IF (T0_SOCFUNC = 5) T0_FI_SocFunc=0. IF (T0_SOCFUNC = 4) T0_FI_SocFunc=0.25. IF (T0_SOCFUNC = 3) T0_FI_SocFunc=0.50. IF (T0_SOCFUNC = 2) T0_FI_SocFunc=0.75. IF (T0_SOCFUNC = 1) T0_FI_SocFunc=1. IF (T0_HEALTH = 0) T0_FI_Health=1. IF (T0_HEALTH = 1) T0_FI_Health=0.9. IF (T0_HEALTH = 2) T0_FI_Health=0.8. IF (T0_HEALTH = 3) T0_FI_Health=0.7.
5 IF (T0_HEALTH = 4) T0_FI_Health=0.6. IF (T0_HEALTH = 5) T0_FI_Health=0.5. IF (T0_HEALTH = 6) T0_FI_Health=0.4. IF (T0_HEALTH = 7) T0_FI_Health=0.3. IF (T0_HEALTH = 8) T0_FI_Health=0.2. IF (T0_HEALTH = 9) T0_FI_Health=0.1. IF (T0_HEALTH = 10) T0_FI_Health=0. *** Tasks and occupations in daily life ***. IF (T0_GARS_HH=1) T0_FI_GARS_HH=0. IF (T0_GARS_HH=2) T0_FI_GARS_HH=0.33. IF (T0_GARS_HH=3) T0_FI_GARS_HH=0.66. IF (T0_GARS_HH=4) T0_FI_GARS_HH=1. IF (T0_GARS_SHOP=1) T0_FI_GARS_SHOP=0. IF (T0_GARS_SHOP=2) T0_FI_GARS_SHOP=0.33. IF (T0_GARS_SHOP=3) T0_FI_GARS_SHOP=0.66. IF (T0_GARS_SHOP=4) T0_FI_GARS_SHOP=1. IF (T0_LASA_MED=1) T0_FI_LASA_MED=0. IF (T0_LASA_MED=2) T0_FI_LASA_MED=0.33. IF (T0_LASA_MED=3) T0_FI_LASA_MED=0.66. IF (T0_LASA_MED=4) T0_FI_LASA_MED=1.
6 IF (T0_LASA_TRANSP=1) T0_FI_LASA_TRANSP=0. IF (T0_LASA_TRANSP=2) T0_FI_LASA_TRANSP=0.33. IF (T0_LASA_TRANSP=3) T0_FI_LASA_TRANSP=0.66. IF (T0_LASA_TRANSP=4) T0_FI_LASA_TRANSP=1. *** Dental care is counted as one deficit ***. IF (T0_MOUTH_PAIN=1) T0_FI_MOUTH_PAIN = IF (T0_MOUTH_PAIN=0) T0_FI_MOUTH_PAIN = 0. IF (T0_MOUTH_CHEW=1) T0_FI_MOUTH_CHEW = IF (T0_MOUTH_CHEW=0) T0_FI_MOUTH_CHEW = 0. IF (T0_MOUTH_DRY=1) T0_FI_MOUTH_DRY = IF (T0_MOUTH_DRY=0) T0_FI_MOUTH_DRY = 0. IF (T0_MOUTH_SWAL=1) T0_FI_MOUTH_SWAL = IF (T0_MOUTH_SWAL=0) T0_FI_MOUTH_SWAL = 0. COMPUTE T0_FI_MOUTH = SUM (T0_FI_MOUTH_PAIN, T0_FI_MOUTH_CHEW, T0_FI_MOUTH_DRY, T0_FI_MOUTH_SWAL). *** Compute T0_FI ***. *** First determine the number of missing values ***. COMPUTE FI_short_missing_number =NMISS (T0_FI_Health, T0_FI_EQ_mob, T0_FI_EQ_selfcare, T0_FI_EQ_act, T0_FI_EQ_pain, T0_FI_EQ_mood, T0_LASA_MEMO1, T0_LASA_FALL, T0_FI_GARS_HH,
7 T0_FI_GARS_SHOP, T0_FI_LASA_MED, T0_FI_LASA_TRANSP, T0_FI_MOUTH, T0_FI_nerv, T0_FI_calm, T0_FI_blue, T0_FI_happy, T0_FI_down, T0_FI_SocFunc). *** Calculate the total number of deficits accrued ***. COMPUTE Frailty_short_total = sum (T0_FI_Health, T0_FI_EQ_mob, T0_FI_EQ_selfcare, T0_FI_EQ_act, T0_FI_EQ_pain, T0_FI_EQ_mood, T0_LASA_MEMO1, T0_LASA_FALL, T0_FI_GARS_HH, T0_FI_GARS_SHOP, T0_FI_LASA_MED, T0_FI_LASA_TRANSP, T0_FI_MOUTH, T0_FI_nerv, T0_FI_calm, T0_FI_blue, T0_FI_happy, T0_FI_down, T0_FI_SocFunc). *** Examine different methods to address missing ***. *** Complete case analysis - all deficits must be present (no missing values) ***. *** WARNING --> Results in high levels of missing values ***. DO IF FI_short_missing_number = 0. COMPUTE T0_FI_short_complete_case=T0_Frailty_short_total/19. END IF. *** Establish a minimum number of permissible missing deficits ***. *** Adjustment of base for missing data ***. IF (FI_short_missing_number <= 3) FI_short_corrected=Frailty_short_total/(19- FI_short_missing_number).
8 *** Dichotomize the frailty index ***. *** No established threshold, cut-offs generally made at either 0.25 or 0.20 (see Searle et al above) ***. IF (FI_short_corrected ge 0.25) FI_short_binary_25cut=1. IF (FI_short_corrected lt 0.25) FI_short_binary_25cut=0. IF (FI_short_corrected ge 0.2) FI_short_binary_20cut=1. IF (FI_short_corrected lt 0.2) FI_short_binary_20cut=0.
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