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1 .5159 : : : :. :. 84 : Burden Iranian Version of Caregiver.. Neuropsychiatric Inventory () /4 39/3 : ebrahemen@gmail.com : 89/10/4 : 89/8/26: :. : 40 (116 58). : (1) ( ) (35) ). () ( (36).(1) ( ) (23) ().(4)

2 .(5) 95.(61012) ()..(7) (891011).(12) ) ( ) (......( ).. (Delusion)..(10) ().(10).(16). ) (. 84 ) (() Iranian Version of Caregiver Burden Neuropsychiatric Inventory.(1718) (Demographic).. (content) (construct) ) (Inter Rater (Frequency) %79 (Severity) %86.(61015) 3. )

3 : 3/ (. 12.(15) 1) (4 1) (3..(101518) Iranian Version of Caregiver Burden. 29 ) (. ) ( 98/6 99/ ICC ) ( 4) (0 116 ) 0 (116.(17). Caregiver Burden 2. T test (ANOVA) (Correlation) ) (.. Dummy» «.» «. 84 ) ( ) (. ) ( (6/7) 76/5 (4/9) 4/8. ) ( ) ( 10/7 45/1. 2/76 4/6. 85/7) ( / ) ( ) (58. 39/3 34/5 2/4 8/ Bi variate

4 /54 ( ) 1 12 (%14/3) 43 (%51/2) 30 (%23/8) 9 (%10/7) 53/54(8/11) /24(5/2) 45/1 (32) 66 (%78/6) 12 (%14/3) 3 (%3/5) 3 (%3/5) 27 (%32/1) 39 (%46/4) 8 (%9/5) 10 (%12) (777482) ( n =84) /5(6/7) 48(57/1%) 36(42/9%) 4/8(4/9) 6 (%7/2) 12 (%14/3) 66 (%78/5) 10/7 (1/75) 2/76 4/6 (1/9) 50 (%59/6) 1 (%1/2) 30 (%35/7) 3 (%3/5) 62 (73/8) 16 (%19) 6 (%7/2) /83 (13/5) () ( /) () () ( /) ( ) () * 58/85 (25). *

5 : 5/ 1 84 ) (. (Pvalue <0/006) 0/302).(r= 2 Bivariate (S.D) Pvalue r 14 (1/3) 0/55 (3/7) 1/47 0/040 0/ (1/4) 0/85 (2/7) 1/5 0/604 0/ (1/5) 0/76 (2/7) 1/27 0/185 0/ (1/7) 1/25 (4/2) 2/7 0/293 0/ (1/3) 0/64 (2/6) 1/13 0/943 0/ (1/8) 1/2 (3/7) 2/21 0/032 0/ (1/5) 0/77 (2/7) 1/24 0/034 0/ (1/5) 0/75 (2/9) 1/42 0/046 0/222 2 (0/3) 0/05 (1/7) 0/2 0/843 0/ (1/6) 0/85 (3/4) 1/66 0/032 0/ (1/8) 1/25 (3/5) 2/26 0/521 0/072 7 (0/9) 0/3 (1/4) 0/38 0/306 0/115 * (13/5) 14/83 0/006 0/302 *

6 /6 (Pvalue <0/006). 21/7 (Pvalue <0/005) 27/8 25/6.(Pvalue<0/008). ( ) P Bivariate. 1/5 (P value<0/025).(pvalue<0/022) 1/7 3 (β) β 95 β t < 0/001 90/ / / / 346 (Constant) 0/228 0/ 137 4/ / 275 6/ 922 1/ 218 ( ) 0/232 0/ / 547 8/ / 929 1/ 206 0/372 0/ / 547 8/ 182 6/ 683 0/ 898 0/710 0/ / / 924 2/ 515 0/ 374 0/008 0/ / 166 7/ / 584 2/ 750 0/593 0/ / / 314 6/ 357 0/ 536 0/168 0/ / 891 5/ / 105 1/ 394 0/006 0/ / 999 6/ / 677 2/ 826 0/005 0/ / 877 8/ / 815 2/ 915 0/056 0/ 199 5/ 812 0/ 077 2/ 867 1/ 945 0/025 0/ 233 0/ 191 2/ 765 1/ 478 2/ 295 0/022 0/ 213 0/ 243 3/ 076 1/ 659 2/ 340 < 0/001 0/ / 141 4/ / 488 3/ 706

7 : 57/ Backward ) (. Variance Inflation Factor(VIF) ) VIF 3 3/6 1/7 (. (co linearity). 3. 0/542 ) (.(R 2 =0/542).(5). ) (....(21).(10).(16) 14/8 (411).(615) 85...(6710) Bivariate....» «.» «21/7 27/8. 13/1. ).(Pvalue=0/168).(19)

8 ... ) (.. 25/5.(Pvalue =0/008). (5620) ) (...( ) ) (..... Bivariate ) (2. ) (. ).(3. ) (.. ) (..» «. 116) (58 40

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10 8 / Abstracts Iranian Journal of Epidemiology 2011; 7(2): Original Article Psychiatric Symptoms in Patients with Dementia: Prevalence and their Relationship with Caregiver Burden Abdollahpour I 1, Noroozian M 2, Nedjat S 3, Majdzadeh R 4 1 Master of epidemiology, Boukan Health Network. Urmia University of Medical Science, PhD Candidate in Epidemiology, Epidemiology and Biostatistics Department of Public Health School, Tehran University of Medical Sciences, Tehran, Iran 2 Associate Professor of Neurology, Tehran University of Medical Science, Tehran, Iran 3 Epidemiology and Biostatistics Department of Public Health School, Knowledge Utilization Research Center, Tehran University of Medical Sciences, Tehran, Iran 4 Professor, Epidemiology and Biostatistics Department of Public Health School, Knowledge Utilization Research Center, Tehran University of Medical Science, Tehran, Iran Corresponding author: Abdollahpour I., ebrahemen@gmail.com Background & Objectives: Although it is important to study the association between caregiver burden and individual with dementia, a little has been paid attention to this issue in Iranian population therefore the aim of study was to investigate the frequency of psychiatric symptoms and patients with dementia and caregiver burden associated with individual with dementia. Methods: In this study 84 patients who had referred to Iran Alzheimer s Association, along with their caregivers were included in our study. Iranian Version of Caregiver Burden and questionnaires were employed. Factors affecting factors on burden was analyzed by multivariate linear regression. Results: Our findings showed that there was at least one psychiatric disorder in all patients. Among all psychiatric symptoms delusion and elation had the highest and lowest rates with 39.3 and 2.4 percentages, respectively. Linear regression indicated that indifference and irritability symptoms were the effective psychiatric symptoms on the amount of burden placed on the caregivers. Conclusion: The symptom frequency of irritability and other symptoms showed a statistically significant positive correlation with caregiver's D score. These findings suggest that improvement of treatments for delusions, irritability among dementia patients may reduce caregiver burden. Keywords: Dementia, Psychiatric symptoms, Caregiver burden, Prevalence, Iran