SAFETY E-CIGS: CLINICAL STUDIES
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1 SAFETY E-CIGS: CLINICAL STUDIES
2 SAFETY ECIGS: clinical studies Source: Safety evaluation and risk assessment of electronic cigarettes as tobacco cigarette substitutes: A systematic review. Ther Adv Drug Saf, 2014, 5:
3 SAFETY ECIGS: clinical studies BLOOD COUNT Source: Acute effects of electronic and tobacco cigarette smoking on complete blood count. Food Chem Toxicol., 2012, 50:
4 SAFETY ECIGS: clinical studies LUNG FUNCTION NOT significantly affected by e-cigarette smoking (active or 1 h passive e-cigarette smoking) passive tobacco cigarette smoking significantly affected by active tobacco cigarette smoking Source: Acute impact of active and passive electronic cigarette smoking on serum cotinine and lung function. Inhal Toxico,. 2013, 25:
5 SAFETY ECIGS: clinical studies CORONARY CIRCULATION Electronic cigarette use does not affect the oxygenation of the heart no immediate effects v= ztrgafeg4 Source: Immediate effects of electronic cigarette use on coronary circulation and blood carboxyhemoglobin levels: comparison with cigarette smoking. European Heart Journal, 2013, 34, Issue suppl 1, 01.
6 SAFETY ECIGS: clinical studies MYOCARDIAL FUNCTION Source: Acute effects of using an electronic nicotine-delivery device (electronic cigarette) on myocardial function: Comparison with the effects of regular cigarettes. BMC Cardiovascular Disorders, 2014, 14:78.
7 SAFETY ECIGS: clinical studies HARM REVERSAL IN ASTHMATIC SMOKERS Source: Effect of smoking abstinence and reduction in asthmatic smokers switching to electronic cigarettes: Evidence for harm reversal. Int. J. Environ. Res. Public Health, 2014, 11:
8 SAFETY ECIGS: clinical studies HARM REVERSAL IN ASTHMATIC SMOKERS Source: Effect of smoking abstinence and reduction in asthmatic smokers switching to electronic cigarettes: Evidence for harm reversal. Int. J. Environ. Res. Public Health, 2014, 11:
9 SAFETY ECIGS: propylene glycol However, the larger data set indicates that these compounds have low sensitization potential in animal studies, and therefore are unlikely to represent human allergens. The existing safety evaluations of the FDA, USEPA, NTP and ATSDR for these compounds are consistent and point to the conclusion that the propylene glycols present a very low risk to human health. Source: A toxicological review of the propylene glycols. Critical Reviews in Toxicology, 2013, 43:
10 NICOTINE SAFETY Source: How much nicotine kills a human? Tracing back the generally accepted legal dose to dubious self-experiments in the nineteenth century. Arch Toxicol, 2014, 88: 5-7.
11 NICOTINE SAFETY Effect of long-term (two years) inhalation of nicotine on rats: compared to controls NO increase in mortality in atherosclerosis in frequency of tumors No indication for any harmful effect of nicotine when given in its pure form by inhalation. Source: Long-term effects of inhaled nicotine. Life Science, 1996, 58:
12 NICOTINE SAFETY Source: Adverse events associated with nicotine replacement therapy (NRT) for smoking cessation. A systematic review and meta-analysis of one hundred and twenty studies involving 177,390 individuals. Tobacco Induced Diseases, 2010, 8:8.
13 NICOTINE SAFETY Source: Adverse events associated with nicotine replacement therapy (NRT) for smoking cessation. A systematic review and meta-analysis of one hundred and twenty studies involving 177,390 individuals. Tobacco Induced Diseases, 2010, 8:8.
14 NICOTINE SAFETY Source: Does nicotine replacement therapy cause cancer? Evidence from the Lung Health Study. Nicotine & Tobacco Research, 2009, 11:
15 NICOTINE SAFETY Source: Cardiovascular events associated with smoking cessation pharmacotherapies: A network meta-analysis. CIRCULATIONAHA v1
16 NICOTINE SAFETY Source:
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