Crestor vs lipitor for women

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1 Crestor vs lipitor for women If you've already found that your cholesterol levels are getting dangerously out of sync, you can. American Heart Association: High Risk Factors and Coronary Heart Disease., and the actual numbers measuring HDL and LDL cholesterol are not nearly as important as the ratio, which should remain around 2:1 (HDL:LDL). Atorvastatin oral tablet is used for long-term treatment. It comes with risks if you don't take it as prescribed. If you miss doses or don't take the drug on schedule:. Get the latest tips on diet, exercise and healthy living. Atorvastatin may increase your blood sugar levels. You and your doctor should monitor your blood sugar levels carefully while you're taking this drug. Typical starting dosage: mg taken once per day., or "nasopharyngitis." Up to 12.9 percent of patients on Lipitor can expect to form a cold within a short period of time of starting

2 Lipitor. No studies have been done on the recurrence of colds or damage to the immune system that may also occur later on for those taking this drug long term. Strengths: 10 mg, 20 mg, 40 mg, and 80 mg. This Dr. Axe content is medically reviewed or fact checked to ensure factually accurate information. Insulin wasn't the only affected element, however. The study cites a reduced blood level of several vital nutrients by 22 percent, including alphatocopherol, beta-carotene and coenzyme Q10. This does not bode well, as one of the antioxidant qualities of. cold symptoms such as runny nose, sneezing, and coughing diarrhea gas heartburn joint pain forgetfulness confusion. 3 Tips To Make Your Wine Habit A Little Healthier. Lab tests for your liver may be abnormally high while you're taking atorvastatin and you may have liver problems. Your doctor will monitor this while you're taking this drug. 3. May Reduce the Risk of Liver Disease. wherever possible, avoiding sugars and refined carbohydrates, and limiting your alcohol and caffeine intake will have great impact on the way your body functions. Swelling of the eyelids or around the face. The FDA recognizes statins to be responsible for occasional development of diabetes but claims, "Clearly we think that the heart benefit of statins outweighs this small increased risk.". In addition to these fairly extensive Lipitor side effects, you can find a massive list of more side effects that range from mild to severe. Lipitor is also associated with: 10 Best Anti-Anxiety Apps That Will Help You De-Stress. are not the answer. High cholesterol and its associated treatments are another Western medicine attempt to treat symptoms of an underlying problem: horrendous dietary habits that cripple the body's natural ability to operate. cme/ce Parents Often Unaware of Adolescents' Suicidal Thoughts. In the recent past, these differences were explained by theories of hormonal differences between men and women

3 theories that led to the widespread prescription of hormone therapy (HT) for menopausal women to protect against heart disease. However, in 2002, the groundbreaking Women's Health Initiative tested this hypothesis and found the opposite to be true; and, most recently, additional evidence has linked HT with an increased risk of developing breast cancer. The rationale for prescribing these drugs is based on the cholesterol hypothesis which argues that drugs that can lower total cholesterol (TC) or LDL cholesterol (often called "bad" cholesterol) or raise HDL ("good" cholesterol) will prevent heart disease. The measurement of cholesterol lowering is called a surrogate endpoint, which is different from the measurement of the hard endpoints of decreased heart disease or death. Having cholesterol is often thought of as a virtual disease state. However, cholesterol performs many vital functions in the body: it maintains cell wall structure, is crucial for hormone and Vitamin D synthesis, bile salt production and digestion, brain and neuron function. It is critical in fetal development and is an essential component of breast milk. Researchers Harriet Rosenberg and Danielle Allard at Women and Health Protection recently reviewed the effectiveness and safety of statin medications for women in Canada. They were looking for the evidence base for use of this widely prescribed class of drugs. What they found was evidence for caution. Nonetheless, he pointed out the increased risk appears early in Crestor treatment and at low doses mg. Moreover, during the press briefing Dr. Grundy flatly stated that even with the report from Dr. Karas and colleagues he had "no evidence that one statin is safer than another.". With all of the words With the exact phrase With at least one of the words Without the words. There are many risk factors associated with heart disease, including smoking, diet, poverty and exposure to environmental pollutants

4 which are modifiable, but cholesterol has become the most prominent and feared risk, perhaps because it is the only one that can conveniently be addressed by taking a pill. Dr. Karas compared the adverse event reporting rates for Pravachol, Zocor, Lipitor, and Crestor using a composite endpoint of rhabdomyolysis, proteinuria, nephropathy or renal failure. Richard H. Karas, M.D., Ph.D., director of preventive cardiology and the Woman's Heart Center at Tuft-New England Medical Center, noted that the absolute risk remains low: 28 events per million prescriptions for Crestor, versus 13 per million for Zocor, 3.5 per million for Pravachol, and 4.3 per million for Lipitor. That said, they concluded that it "would seem prudent at the current time for doctors to consider other statins as firstline therapy, to initiate therapy in appropriate patients at lower doses, to consider combination LDL-cholesterollowering therapy (e.g. statin combined with ezetimide), and to vigilantly monitor for adverse events if rosuvastatin is used.". Harriet G. Rosenberg, PhD is an Associate Professor in the Health and Society Program at York University doing research on women and health. Danielle Allard is a PhD candidate at the Faculty of Information Studies at the University of Toronto. She works as a research assistant at Women and Health Protection. Analysis by researchers at the Therapeutics Initiative at the University of British Columbia, which looked at a total of 10,990 women, also found no evidence that statin therapy reduced coronary events in women without heart disease. Advise patients who ask about statin safety that the drugs are safe when appropriately prescribed. Caution patients about the danger of stopping statin therapy. Discuss this study with patients currently taking Crestor and point out that the risks reported here are very low. Patients who want to discontinue the drug should be switched to another statin. He added that even when muscle or

5 TEENney problems are reported those "events seem dose related and will reverse when the drug is stopped or the dose lowered." Dr. Grundy said, too, that most adverse events occur in patients who "don't meet AHA/ACC criteria for statin therapy.". The statin guidelines list as high risk individuals: frail elderly (over age 80) who have small body frames, patients with multisystem disease, patients following surgery, patients taking multiple drugs, patients consuming more than a quart of grapefruit juice daily, and patients who abuse alcohol. Weed and Teen Brains; TEENs' Seizure Smartband; Parkinson's Subtyping. Statins have been described as "so safe they should be in the drinking water." Yet, evaluating the safety of statin therapy for women is exceptionally difficult due to a lack of gender-based analysis in research. Also, only two of 14 key statin drug trials have released all of their serious adverse events data despite repeated requests by researchers. Access to these unreleased data is urgently needed to thoroughly evaluate the risks as well as the benefits of statins. There are many on-line groups of former statin users, and their partners, who describe experiences with cognitive and memory impairments, including amnesia, episodes of depression, mood problems, especially extreme irritability, peripheral neuropathy, muscle pain and exercise intolerance, weakness and fatigue, blood sugar problems, and the unmasking of underlying genetic conditions (e.g., Parkinson's disease, ALS) that are disabling or life-altering. Three Book Reviews: Reading About Women's Experiences of Breast Cancer. Yet, Dr. Karas and colleagues did not recommend that Crestor be withdrawn from the market. Instead, they suggested "that vigilant surveillance for adverse effects during initiation of therapy may help ameliorate the risk of toxicity when rosuvastatin is used.". Since 2004, Dr. Beatrice Golomb

6 and colleagues at the University of California (San Diego) have been compiling information on statin-related problems, including memory loss, mood and violent or aggressive behaviour. Their work has found associations between aggressive behaviour and statin use not seen in clinical trials. This research found that some statin users who had mood and memory problems also had muscle problems and weakness, which would affect their ability to undertake proven heart-protective exercise programs. Their research has estimated that, while clinical trials may report 1 to 7% of patients experience adverse drug reactions, the number of adverse reactions with statin use may be closer to 15%. Warnings and Precautions (5.1) and Clinical Pharmacology (12.3) ]. Lipitor is classified as a statin drug; it works by inhibiting an enzyme involved in cholesterol production in the body. Research indicates that magnesium has statin effects as well. Consult your doctor before taking magnesium supplements if you also use Lipitor. In the METEOR study, involving 981 participants treated with rosuvastatin 40 mg (n=700) or placebo (n=281) with a mean treatment duration of 1.7 years, 5.6% of subjects treated with Crestor versus 2.8% of placebo-treated subjects discontinued due to adverse reactions. The most common adverse reactions that led to treatment discontinuation were: myalgia, hepatic enzyme increased, headache, and nausea [see Clinical Studies (14.8) ]. Atorvastatin may increase your blood sugar levels. Your doctor may adjust your diabetes medications if this happens. Warnings for other groups. After initiation or upon titration of Crestor, lipid levels should be analyzed within 2 to 4 weeks and the dosage adjusted accordingly. The following serious adverse reactions are discussed in greater detail in other sections of the label:. While eating a healthy diet can sometimes improve your

7 cholesterol levels, atorvastatin can help them even more. If you don't take atorvastatin, your cholesterol levels may not be controlled. This may raise your risk for heart attack or stroke. In heterozygous familial hypercholesterolemia, the recommended dose range is 5 to 10 mg orally once daily in patients 8 to less than 10 years of age, and 5 to 20 mg orally once daily in patients 10 to 17 years of age. Clinical Studies ]. Doses should be individualized according to the recommended goal of therapy [see INDICATIONS AND USAGE and. Initiate Crestor therapy with 5 mg once daily. The dose of Crestor should not exceed 10 mg once daily [see Warnings and Precautions (5.1), Drug Interactions (7.3) and Clinical Pharmacology (12.3) ]. Having TEENney problems raises your risk for muscle breakdown while taking atorvastatin. Your doctor may monitor you more closely for muscle problems. Drugs.com: Drug Interactions Between Lipitor and Magnesium Hydroxide. Crestor is indicated as adjunctive therapy to other lipidlowering treatments (e.g., LDL apheresis) or alone if such treatments are unavailable to reduce LDL C, Total C, and ApoB in adult patients with homozygous familial hypercholesterolemia. Lab tests for your liver may be abnormally high while you're taking atorvastatin and you may have liver problems. Your doctor will monitor this while you're taking this drug. For patients with severe renal impairment (CL cr 3 times the upper limit of normal occurred in 1.1% of patients taking Crestor versus 0.5% of patients treated with placebo. Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

8 Adverse reactions reported in 2% of patients in placebo-controlled clinical studies and at a rate greater than placebo are shown in Table 1. These studies had a treatment duration of up to 12 weeks. Table 1: LIPITOR Tablet Strengths and Identifying Features. Rhabdomyolysis with myoglobinuria and acute renal failure and myopathy (including myositis) [see Warnings and Precautions (5.1) ]. Muscle problems. Symptoms can include: unexplained muscle weakness, tenderness, or pain tiredness. transient ischemic attack ( TIA ) within the previous 6 months treated with LIPITOR 80 mg (n=2365) or placebo (n=2366) for a median follow-up of 4.9 years, there was a higher incidence of persistent hepatic transaminase elevations ( 3xULN twice within 4-10days) in the atorvastatin group (0.9%) compared to placebo (0.1%). Elevations of CK ( > 10 x ULN) were rare, but were higher in the atorvastatin group (0.1%) compared to placebo (0.0%). Diabetes was reported as an adverse reaction in 144 subjects (6.1%) in the atorvastatin group and 89 subjects (3.8%) in the placebo group [see WARNINGS AND. The material appearing on LIVESTRONG.COM is for educational use only. It should not be. The dosage of LIPITOR in patients with HoFH is 10to 80mg daily. LIPITOR should be used as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) in these patients or if such treatments are unavailable.