Ablation of atrial fibrillation Techniques and workflow in AF rotors. G. Hindricks and Ph. Sommer
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1 IDSS - Israel Tel Aviv 2016 Ablation of atrial fibrillation Techniques and workflow in AF rotors G. Hindricks and Ph. Sommer University of Leipzig - Heart Center - Department of Electrophysiology
2 Presenter Disclosure Information Gerhard Hindricks/Department of Electrophysiology has received scientific grants and research & development grants through the University Leipzig / Heart Center from St. Jude Medical, Biotronik, Boston Scientific, and Volkswagen Foundation. No personal relations to disclosure.
3 Catheter ablation at Heart Center Leipzig
4 Catheter ablation of atrial fibrillation at the Heart Center Leipzig: Agenda Infrastructure Work flow Treatment standards Techniques and technologies Quality control Follow-up
5 Ablation of atrial fibrillation general thoughts Precise and personalized indications - what s the profit and what are the risks? Optimal patient preparation - meaningful resource utilization - do the necessary but don t waste resources Select the best treatment technology available - 3-D mapping systems / cryo balloon / FIRM - steerable sheath technology - force sensing catheters Choose the optimal treatment technique - PVI plus substrate modification plus rotor ablation
6 AF ablation at the Heart Center Leipzig: Infrastructure 5 cathlabs - 4 advanced mapping techologies - Stereotaxis, Mediguide, UniView, - Rhythmia, Topera - MRI interventional suite 65 patient beds for EP (plus ICU beds) 10 outpatient beds outpatient clinic dedicated AF follow-up center (Cardiocenter)
7 MRI
8 AF ablation at the Heart Center Leipzig: Work flow Day 1 - history, physical examination, blood tests - ECG, stress tests (if necessary) - informed consent TTE, MRI/CT Day 2 - cath labs start at 06: AF cases - puncture 07:30 (sharp) - after ablation 2h close observation - back to normal ward
9 AF ablation at the Heart Center Leipzig: Work flow Day 3 - ECG, TTE - physical examination - 7 day ECG, - follow-up information letter - potential discharge (or on Day 4)
10 AF ablation at the HZL: Treatment standards start analgosedation with propofol 5 punctures (4 veins, 1 artery) - 4F, 5F, 6F, 8F, 12F catheters RVA, CS, 1/2 LA single/double TSP with steerable sheaths heparine administration (ACT 300) accept INR < 3.0, 5000 IE before TSP check pts. status
11 Specific workflow for FIRM ablation
12 Sommer et al.; JCE 2015 Techniques and Workflow for AF Rotors Patients selection for FIRM ablation
13 Specific issues for FIRM ablation MRI assessment of LA / RA size Usually, patients enter the lab in AF If not, AF is induced Sustained AF could be induced in all pts. > 10 min ongoing AF before FIRM mapping
14 Planning the case: left atrial size measured from MRI
15
16 Sommer et al.; JCE 2015 Techniques and Workflow for AF Rotors Workflow for FIRM ablation
17 Leipzig workflow for FIRM ablation Take geometry of RA Check ACT (>300) Position 1 RA: high right atrium Take data, analyze (and ablate)
18 Workflow for the case: step 1
19 Leipzig workflow for FIRM ablation Take geometry of RA Check ACT (>300) Position 1 RA: high right atrium Take data, analyze (and ablate) Position 2 RA: basal right atrium Take data, analyze (and ablate)
20 Workflow for the case: step 2
21 Leipzig workflow for FIRM ablation Take geometry of RA Check ACT (>300) Position 1 RA: high right atrium Take data, analyze (and ablate) Position 2 RA: basal right atrium Take data, analyze (and ablate) Go transseptal Take geometry of LA
22 Clinical study for AF ablation using magnetic navigation (III)
23 Leipzig workflow for FIRM ablation Go transseptal Take geometry of LA Position 1 LA: left side / LUPV
24 Workflow for the case: step 3
25 Leipzig workflow for FIRM ablation Go transseptal Take geometry of LA Position 1 LA: left side / LUPV Take data, analyze (and ablate) Position 2 LA: LA central
26 Workflow for the case: step 4
27 Workflow for the case: step 5
28 Leipzig workflow for FIRM ablation Go transseptal Take geometry of LA Position 1 LA: left side / LUPV Take data, analyze (and ablate) Position 2 LA: LA central Take data, analyze (and ablate) Position 3 LA: right side
29 Workflow for the case: step 6
30 Workflow for the case: summary of cath. positions
31 Workflow for the case: ablation sites
32 Case example: 45 year old male patient LA diameter 40mm, LVEF 65%; EHRA III 3 previous ablation procedures: 2011: VSD closure with cryoablation 10/2013 PVI alone 08/2014 PV still isolated, additional box lesion Recurrences of AF appr. 1 week after ablation/cv
33 Case example: RA + LA: 0 rotors!
34 Case example: FIRM mapping in LPSVC
35 Case example: ablation of 6 rotor regions
36 Case example: redo after 9 months
37 Summary FIRM ablation can be well implemented in efficient ablation workflow. As always: development and systematic application of workflow standards is important for safe, effective, and economically balanced procedures. The next step will be the developement and evaluation of standard workflow for FIRM stabd alone procedures.
38
39 Catheter ablation of atrial fibrillation: Leipzig perspective - JHRS 2014 Isolation of the pulmonary veins II III V1 PV 1/2 PV 3/4 PV 5/6 PV 7/8 PV 9/10 CS 1/2 CS 3/4 CS 5/6 CS 7/8 RVA
40 Catheter ablation of atrial fibrillation: Leipzig perspective - JHRS 2014 Isolation of the pulmonary veins II III V1 PV 1/2 PV 3/4 PV 5/6 PV 7/8 PV 9/10 CS 1/2 CS 3/4 CS 5/6 CS 7/8 RVA
41 Catheter ablation of atrial fibrillation: Leipzig perspective - JHRS 2014 Isolation of the pulmonary veins II III V1 PV 1/2 PV 3/4 PV 5/6 PV 7/8 PV 9/10 CS 1/2 CS 3/4 CS 5/6 CS 7/8 RVA
42 Catheter ablation of atrial fibrillation: Leipzig perspective - JHRS 2014 AF ablation at the HZL: Treatment standards verification and documentation of complete circumferential isolation induction via CS and LAA - CL 300, 250, 200 ms / 15 sec. further treatment according to specific protocols withdraw catheters and sheaths after administration of protamine
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