NEURO-DEGENERATION CONCEPT
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1 Brain guard. NEURO-DEGENERATION CONCEPT Unique Brain Protection Therapy.
2 New therapy potentials new confidence. Neurodegenerative diseases are defined as a series of diseases that primarily affect the nerve cells of the human brain. They are caused by accumulations of proteins (so-called fibrins) that have not been broken down in the area of the nerve cell synapses, thereby blocking the transfer of information from cell to cell and leading to motor and cognitive dysfunctions. Nerve cells are the building blocks of the nervous system, which includes the brain and spinal cord. The assumption that nerve cells do not or cannot regenerate has been proved to be incorrect by the latest scientific research. 2
3 Nerve cells can be regenerated from specific stem cells, such as through the so-called nerve growth factor, in which especially PQQ plays a decisive role. This opens the door to a novel treatment concept for neurodegenerative diseases like dementia, Parkinson, Alzheimer and ALS. The active ingredients that we have selected and put together in this concept constitute an extensive therapy package that help patients to stabilise themselves and can lead to a significant delay of the symptoms. 3
4 The therapy modules MITO-ENERQ + PQQ Dietary supplement with pyrroloquinoline quinone (PQQ) and highly absorbable coenzyme Q10. Ingredients per capsule: coenzyme Q10 complex 300 mg, which includes 60 mg of coenzyme Q10 and 40 mg of pyrroloquinoline quinone. The properties of Q10: Potential radical scavenger Improves the functional capability of mitochondria (the power plants of cells) Increases the number of mitochondria in the brain As coenzyme, it controls 95% of the entire body energy (ATP) through oxidative phosphorylation Stabilises the cell membrane The properties of PQQ: Promotes more mitochondrial biogenesis Increases mitochondrial efficiency Has a performance-enhancing effect Promotes the production of NGF (nerve growth factor) Takes over an important healing function after post-traumatic brain injuries SOD Dietary supplement with the antioxidants superoxide dismutase, 5-hydroxytyrosol and epigallocatechin gallate. Ingredients per capsule: SOD extract 40 mg, activity 560 IU, 5-hydroxytyrosol 100 mg, green tea extract 200 mg that includes 100 mg of EGCG 4
5 The properties of SOD: Removes oxygen radicals produced by the mitochondria Mitigates inflammatory processes The properties of 5-hydroxytyrosol: Counteracts oxidative stress in the brain Counteracts hypoxic brain damage (oxygen deficiency in the brain) Dampens an induced inflammation Has a positive effect on insulin resistance in connection with Alzheimer s/dementia Inhibits COMT activity, which leads to higher intracellular DA levels 5
6 The properties of EGCG: Anti-oxidative, anti-carcinogenic, anti-apoptotic, anti-inflammatory The antioxidant stimulates the production of new nerve cells The polyphenols it contains promote oxygen supply, thereby protecting you from memory loss Promotes physical and mental skills, especially in older people Prevents oxidative brain damage GC-BOOST Dietary supplement with vitamin D, colostrum, chondroitin and lactoferrin. Vitamin D contributes to the normal functioning of the immune system. Ingredients per capsule % NRV*: Vitamin D vitamin D 50 mcg 1000%, lactoferrin 200 mg**, chondroitin sulphate 100 mg**, colostrum 80 mg** The properties of GC-Boost: Stimulates the defence cells by means of natural immunomodulating and anti-inflammatory substances and vitamin D Strengthens the health-promoting effects ** nutrient reference values acc. to Regulation (EC) no. 1169/2011. ** no reference values available. NADH Dietary supplement with reduced nicotinamide adenine dinucleotide (NADH). Ingredient per tablet: NADH 50 mg 6
7 The properties of NADH: Increases the ATP level in the cell Stimulates the production of interleukin-6 to support the immune system Improves physical and mental performance Boosts mental performance in case of jetlag and sleep deficit Improves the symptoms of chronic fatigue 7
8 CURCUMIN i.v. Curcumin is effective in neurological diseases. Curcumin inhibits brain damage triggered by exogenous noxious agents such as glutamate and glucose. Curcumin acts preventatively, and also slows down neurological aging processes. Curcumin, like resveratrol, binds numerous important cell proteins (receptors). This leads to complex regulations, which can lead to a longer life. The effect of curcumin on neurological diseases is much more pronounced than that of other plant compounds. SAMe (S-adenosyl methionine) i.v. Increases the concentration of different neurotransmitters in the brain: Noradrenaline (a natural stimulant) Dopamine (creates a feeling of well-being) Serotonin (a natural sedative) SAMe is involved in the functions of the immune system and helps to maintain cell membranes healthy EPINATIV Activates the enzyme telomerase and lengthens the telomeres Increases sensitivity of the hypothalamus for hormonal effects Inhibits spontaneous and induced carcinogenesis (generation of tumours) Normalises the immune function of T cells Normalises the electrolyte balance in the metabolism and circulation Normalises the cholesterol level 8
9 Normalises the uric acid level Normalises the level of gonadotropin hormones (e.g. prolactin) Positive impact on haemodynamics, which means improved blood flow and blood supply in the body s vascular system Regulates the compounds affected by acute inflammation processes Regulates the neuroendocrine system Strengthens and rejuvenates the entire immune system 9
10 Natural power of polyphenol from the vegetation water extracted from olives The base, OLIPHENOLIA i. v, is a fluid phytocomplex, consisting of a natural mix of the polyphenols in olives (hydroxytyrosol, oleuropein-aglycone, tyrosol, verbascoside, chlorogenic acis, secologanoside and many others). The concentration is 20 times higher in comparison with extra virgin olive oil. The filtered and mechanically cold-processed vegetation water is treated without the use of chemical solutions. We have pharmacologically developed this substance and provide it as an infusion preparation with the active ingredient hydroxytyrosol in a homoeopathic carrier solution. The ingredients and field of action of this organic polyphenol cocktail has already been proven in numerous scientific studies. 10
11 OLIPHENOLIA i.v. Organic polyphenol cocktail Positive effects of Oliphenolia i.v.: Vascular health Bowel Antibiotic effect Metabolism/diabetes Nerves Gout Cancer prevention Anti-inflammatory Anti-rheumatic Improved, quicker tissue repair 11
12 The therapy package The therapy plan EPINATIV 2 ml CUR- CUMIN 150 mg SAMe 400 mg OLIPHE- NOLIA i.v. MITO- ENERQ Day 1 Day 2 Day 3 Day 4 Day 5 This regimen is repeated with the same treatment schedule in week 2. This corresponds to a trea month. Of course, the programme can be repeated after a period of 4-6 months, 1-2 x p.a., if this 12
13 SOD GC BOOST NADH Laser i.v. Therapy time 2 hours 2 hours 1 hour 2 hours 2 hours a treatment duration of 10 days, except for the oral products. This is a medication for one, if this is benefi cial from a therapeutic perspective and/or at the request of the patient. 13
14 NEURO-DEGENERATIO Unique Brain Protection Therap ADDITIONAL INTENSIV PQQ PYRROLOQUINOLINE QUINONE Neuroprotective agent helps to protect memory and cognition Discovered 50 years ago Formation of new nerve cells Growth of new mitochondria Prevents diseases caused by aging During the life span, the brain suffers from multiple sources of damage. As these effects accumulate, the result is often the development of neurodegenerative disorders, as well as the risk of stroke resulting from the progressive injury to brain blood vessels. Brain trauma is yet another way in which the delicate microstructure of brain cells is disrupted, leading to loss of cognition and function. The properties of PQQ: Guards the brain against major brain-threatening processes Improves brain energy metabolism 14 THREATS TO THE BRAIN PQQ has been shown to help and protect the brain from neurodegenerative diseases, such as dementia, stroke damage and traumatic brain injury = unrelated events. Fundamental = loss of brain cells
15 ON CONCEPT apy. VE THERAPY: PQQ i.v. PQQ > Protects against Excitotoxicity An excessive glutamate stimulation. Triggers undesired programmed cell death (apoptosis) Major factor in long-term neurodegenerative disorders, stroke and schizophrenia Modulates cellular receptors that triggers excitatory response PQQ > helps to prevent these dangerous responses from occurring in the first place (hippocampus) PQQ > reduces significant cell death and starts recovery PQQ > Prevents Glucose-Induced Brain Damage People with diabetes are 60 % more likely to develop dementia High rates of blood sugar concentration result in high rates of cell death Reverses high-glucose damage, reduces production of ROS Scientists call Alzheimer s disease TYPE III diabetes 15
16 PQQ > Promotes New Mitochondrial Formation Stimulates the formation of new mitochondria and improves the function of existing mitochondria The mitochondria function decreases with age! This is linked to all killer diseases like Parkinson s and Alzheimer s Human studies demonstrated that PQQ improves the mitochondrial function: a daily dose of a 20 mg PQQ supplement has an impact after 3 days + leads to decreased inflammation (CRP, JL 6) PQQ > Leading to the formation of brand-new nerve cells Laboratory experiments show that this occurs through the stimulation of NGF = nerve growth factor A. NGF: small protein molecule = development and maintenance of those nerve cells which are responsible for memory, cognition and learning B. NGF: NGF: important for nerve plasticity. Nerve cells help to form connections allowing communication with each other PQQ > Protecting nerve stem cells and protecting cells against oxidative damage PQQ > Shows or reverses cognitive decline and dementia (current global epidemic!) PQQ > Reduces ischemic damage following a stroke 16
17 PQQ > Reduces the significantly damaged brain tissue-region PQQ > Could be given to stroke patients in the emergency room in order to reduce paralysing brain damage PQQ > Reduces harmful neuroinformation inhibiting the production of two pro-inflammatory signalling molecules 17
18 Intensive therapy: PQQ IV The therapy plan PQQ 40 mg Day 1 Day 2 Day 3 Day 4 D 18
19 Day 5 Day 6 Day 7 Day 8 Day 9 Day 10 19
20 October 2018 Burg Pharmacy Königstein Pharmacist Uwe-Bernd Rose Frankfurter Straße Königstein im Taunus/Germany Tel.: /-37/-38 Fax: therapiebestellung@apotheke-koenigstein.de
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