Study of Rate of Hysterectomy in Patients with Cervical Cancer Referring to Radiotherapy and Oncology Ward of Ahvaz Golestan Hospital in
|
|
- Jacob Parks
- 5 years ago
- Views:
Transcription
1 International Journal of Advanced Biotechnology and Research (IJBR) ISSN , Online ISSN X, Vol-7, Special Issue-Number5-July, 2016, pp Research Article Study of Rate of Hysterectomy in Patients with Cervical Cancer Referring to Radiotherapy and Oncology Ward of Ahvaz Golestan Hospital in Hodjatollah Shahbazian *1, Sholeh Arvandi 1 and Younes Joonaki 2 1 Department of Radiotherapy and Oncology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran 2 School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran *Corresponding author hjshahbazian@yahoo.com ABSTRACT Background and Objective: Cervical cancer is one the common genital cancer in females, and it is the third cancer in women. We can improve the life time and life style of patients with treatment. In early stages the first treatment options are hysterectomy or radiotherapy, while in the progressive stages is chemoradiotherapy. This study aimed to investigate the rate of hysterectomy in patients with cervical cancer. Materials and Methods: This was a retrospective study conducted on the medical records of patients with cervical cancer referring to radiotherapy and oncology ward of Ahvaz Golestan Hospital, Iran during 1995 to Data included age, type of treatment, disease stage, and time of admission and were analyzed with SPSS version 16. Results: Out of 430 patients, 16 patients were in metastatic stage and received palliative chemoradiotherapy and radiotherapy. Of 414 non-metastatic patients, 161 patients (39%) went under hysterectomy. Of the hysterectomy cases, 32% received adjuvant chemoradiotherapy, whereas the 7% underwent other treatments. Conclusion: Rate of hysterectomy in this study was 39% that was similar to some other studies. The trend has not significantly changed during the study period, 1995 to It seems that the surgeons desire to perform hysterectomy or chemoradiotherapy has not changed over the time. Keywords: Cervical cancer, Hysterectomy, Chemoradiotherapy INTRODUCTION Cervical cancer is one of the common genital tract cancers, and in terms of prevalence is the third cancer in women (1) and treatment not only extends the life, but also increases the quality of life. Thus, recognizing its outbreak is of great importance, and it is of few cancers that can be detected in pre-emergence stage (2). Annually, half a million women worldwide are diagnosed with cervical cancer. Twenty-five percent of deaths in women are caused by malignant tumors, 18% of them are cervical cancer, and its prevalence in Iran is 6.64 % (3). Cervical cancer is one of the most prevalent cancers in developing countries. Factors such as sexual ones and reproduction, sex at an early age, low economic and social class, smoking, long-term use of contraceptives are known as risk factors (4). Moreover, human papillomavirus has been detected in 99.7% of patients with cervical cancer (5). Dysplasia of cervical indicates disorder in its growth that is identified with appearance of cancerous and pre-cancerous cells at cervical. Cervical dysplasia often does not have any symptoms, but in 5% of cases, it can advance to cervical cancer. Early detection of these lesions by Pap smear has greatly prevented the progress towards cancer (6). The average age of cervical cancer in the United States is 47 years of age and the peak age is between the ages of 35 to 39 and 60 to 64 (7). Moreover, by screening that was
2 conducted in some countries over 50 years, its prevalence and incidence could be reduced. This is while in most parts of the world, this cancer is the second or third most common cancer in women (8). Treatment of cervical cancer includes simple hysterectomy in stage IA1, radical hysterectomy and pelvic lymphadenectomy in stage IA2, radical hysterectomy and pelvic lymphadenectomy or pelvic radiotherapy along with brachytherapy in stage IB2, radiotherapy along with chemotherapy in IIA-IVA and IB2 stages, and chemotherapy along with palliative radiotherapy in stage IVB (9). Hysterectomy means removal of the uterus and can include the removal of all or part of it, such as fundus, cervix, or its body (10). In this study, by determining the extent of hysterectomy and chemoradiotherapy as the main treatment for cervical cancer, probable changes of surgeons' tend to hysterectomy (primarily in early stage of the disease) were assessed in 15 years. The findings of this study will be effective in educational planning and treatment for the disease and improving the quality of treatment. Materials and Methods This was a retrospective study conducted on the medical records of patients with cervical cancer referring to radiotherapy and oncology ward of Ahvaz Golestan Hospital, Iran during a 15 year period (1995 to 2010). Total of 430 patients were studied in this study. Inclusion criteria included all patients with cervical cancer referring to the radiotherapy and oncology wards of Golestan Hospital, and exclusion criteria included incomplete records of patient. The medical records were studied separately for each year, and hysterectomy and chemoradiotherapy cases performed on patients with cervical cancer each year were examined separately and their processes were checked. Data included age, type of treatment, disease stage, and time of admission and were classified according to inclusion and exclusion criteria. Since the beginning of the study, the patients with cervical cancer were divided into two groups: the first group consisted of patients who had undergone curative treatment (hysterectomy with or without adjuvant chemoradiotherapy and Definitive chemoradiotherapy) and the second group was (metastatic) that had received palliative treatment. The main objective of the study was to study the first group. In this study, the clinical information of patients from the records were extracted and studied without mentioning personal characteristics or their names and no intervention took place for the patient. In recording patient data, the name and individual properties of the patients were not included and during the research, for classification of data, some codes were used instead of their names. It was also tried to practice all religious rules and legal ethics at all stages of the project. Results were statistically analyzed using SPSS 16 statistical software. RESULTS The study was conducted for 15 years from 1995 to 2010 on patients with cervical cancer referring to the Radiotherapy and Oncology wards of Golestan Hospital. About 10 cases due to defects were excluded. Out of the 430 cases 16 patients had been treated with metastatic, and out of 161 remaining patients hysterectomized patients were 39% and non-hysterectomized ones were 61%, which are given separately according to table 1. The hysterectomy in 2009 with 47% was the highest and in 2002 was the lowest with 25%. The hysterectomy during the study years showed no significant change (P-value= 0.097). Table 1. The frequency of hysterectomy in cervical cancer patients separately for each year Hysterectomized Non-hysterectomized Year 33% 3 67% % 5 59% % 4 67% % 4 67% Hojatollah Shahbazian, et al. 946
3 36% 5 64% % 7 63% % 10 60% % 7 74% % 9 68% % 15 66% % 12 64% % 14 61% % 16 53% % 15 57% % 17 53% % 18 56% Out of all non-metastatic cases studied, 61% received (camo) definitive radiotherapy and from hysterectomized patients, 32% of patients with non-metastatic, 85% received (camo) Adjuvant radiotherapy and 15% did not receive (camo) Adjuvant radiotherapy (Figure 1). Figure 1. Percentage of Patients with Cervical Cancer hysterectomized (with or without radiotherapy Adjuvant) and non-hysterectomized Definitive Chemoradiotherapy treatment was done in about 61% of patients and was examined separately for each year. The treatment had the highest rate in 2002 with 74% and the lowest in 2009 had the lowest rate. Definitive Chemoradiotherapy showed no significant changes during the studied years (P-value= 0.05). Table 2. Absolute frequency and the frequency of Definitive Chemoradiotherapy treatment in patients with cervical cancer Absolute Frequency percent Year frequency Hojatollah Shahbazian, et al. 947
4 Total years From among the patients, 61% received Definitive treatment and among them, most of the patients were at Stage IIb and the fewest patients were at Stage Ib (Figure 2). Frequency percent Figure 2. Relative frequency of the disease stages of the patients treated by Definitive Chemoradiotherapy Chemoradiotherapy Adjuvant Treatment was generally carried out for about 32% of patients (85% of hysterectomy patients) and had the highest frequency in 2007 with 44 percent and the lowest was in 2003 with 22% of all patients (Table 3). Table 3. Absolute frequency and frequency percentage of patients treated by Adjuvant Chemoradiation each year Frequency Absolute percent frequency Year Total years The frequency perecentage of the patients who underwent Palliative Chemoradiation due to high stage and being metastatic without hysterectomy was overall 16 patients out of 430 patients studied. The relative frequency percent of Palliative treatment to all therapies was 3.7 percent, and had the highest frequency in 1995 with 10% and the lowest in 2008 and 2009 with zero percent (Table 4). Table 4. Relative frequency of Palliative treatment to all patients separately for years Frequency percent Year Hojatollah Shahbazian, et al. 948
5 Total DISCUSSION According to the results of this study, approximately 39% of patients (254 patients) had undergone hysterectomy. The figure compared with the results of previous studies results that we had showed no significant difference. For example, in a study by Hashemi et al. (11) in Tehran, of 346 patients with cervical cancer, 44 percent underwent hysterectomy, which is roughly consistent to the results obtained in this research. Moreover, in another study by Macintosh et al. (12) conducted in New Zealand, 42% hysterectomy in patients with cervical cancer was obtained that compared with our results showed little difference. The results were more similar in others, for example, in a study by Michael et al. (13), 35.2% of women underwent hysterectomy. Another study conducted in the United States showed that 37% of women with this disease before the age of 70 received hysterectomy. In another study by Gianfranco et al. (14), hysterectomy performed by women gynecological surgeons was 33.3 percent. However, our findings showed some differences with the findings of some previous similar studies. In the study by Coughlan et al. (15) on 210 patients with cervical cancer, 58% hysterectomy was reported and this difference may be due to different methods of incomplete hysterectomy or difference in guidelines relevant in the past years. In a study by Kamura et al. (16), 77% of women with cervical cancer underwent hysterectomy. These differences may be due to stages of patients and surgeons' preferences. CONCLUSION The choice of treatment depends on several other factors in addition to treatment guidelines. As the methods of cervical cancer screening in the area are more prevalent or start at younger ages, the disease of the person will be diagnosed at lower stages. Considering the fact that hysterectomy happens mostly in primary and lower stages, it can be done much more in these areas. Moreover, other factors such as the level of public awareness, the number of hospitals, physician gender, greater availability, more willingness to do surgery, socioeconomic status of patients, and the number of hospital beds are the important factors determining the rate of hysterectomies carried out in any area. The difference in data obtained in our study compared to other studies is probably because of these points. REFERENCES 1. Taherian AAFAS, B. The effective factors in cervical cancer: a case-control study in Isfahan. University of Medical Sciences. 1996;1: Tabeshian A F, F.. Studying the effect of health education on the prevention of cervical cancer in teachers of Isfahan. Islamic Azad University, Tehran University of Medical Sciences. 2009;19: Mobaraki AM, F, Mohebi, Z. Knowledge,. Attitude and Practice of Female Employees in the field of Yasouj hospitals Pap test. Journal of Nursing and Midwifery, Gorgan. 2008;5: Nabaei B B, A.. Tehran University of Medical Sciences Journal. Risk factors in the development of invasive cervical cancer: a case-control study. 2001;59(2): Walboomers JM, Jacobs MV, Manos MM, Bosch FX, Kummer JA, Shah KV, et al. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. The Journal of pathology. 1999;189(1): Ehdaei Vand FN, M.T. Amini Sani F, Chinifurush, M.. Pap smear for cervical dysplasia study in 5000 in the city of Ardabil. 2005;5(1): Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ. Cancer statistics, CA: a cancer journal for clinicians. 2007;57(1): Hojatollah Shahbazian, et al. 949
6 8. Behtash N, Karimizarchi, M.. Cervical cancer: role of vaccines in preventing HPV.. Tehran University Medical Journal. 2006;64: Townsend Jr CM, Beauchamp RD, Evers BM, Mattox KL. Sabiston textbook of surgery: Elsevier Health Sciences; Wu JM, Wechter ME, Geller EJ, Nguyen TV, Visco AG. Hysterectomy rates in the United States, Obstetrics & Gynecology. 2007;110(5): Amuzgarhashemi ZE, A. Kalaghchi, B.. Checking cervical cancer: pathologic characteristics, treatment and follow-up. Tehran University Medical Journal. 2007;65(11): Macintosh M. Incidence of hysterectomy in New Zealand. The New Zealand medical journal. 1987;100(825): Moen M, Noone M, Cholkeri-Singh A, Vassallo B, Locker B, Miller C. Progressive reduction in abdominal hysterectomy rates: impact of laparoscopy, robotics and surgeon factors. Journal of Robotic Surgery. 2014;8(1): Domenighetti G, Luraschi P, Gutzwiller F, Pedrinis E, Casabianca A, Spinelli A, et al. Effect of information campaign by the mass media on hysterectomy rates. The Lancet. 1988;332(8626): Coughlan C, McAuliffe F, Bermingham N, Gleeson N. Vaginal cytology following primary hysterectomy for cervical cancer: Is it useful? Irish journal of medical science. 2006;175(1): Kamura T, Tsukamoto N, Tsuruchi N, Kaku T, Saito T, To N, et al. Histopathologic prognostic factors in stage IIb cervical carcinoma treated with radical hysterectomy and pelvic node dissection an analysis with mathematical statistics. International Journal of Gynecological Cancer. 1993;3(4): Hojatollah Shahbazian, et al. 950
Sciences, Ahvaz, Iran. Received on Accepted on
ISSN: 0975-766X CODEN: IJPTFI Available Online through Research Article www.ijptonline.com A STUDY ON THE AGE OF CERVIX CANCER INCIDENCE IN PATIENTS REFERRING TO RADIOTHERAPY AND ONCOLOGY WARD OF AHVAZ
More informationand treating joins with the top of canal). at risk for cervical carcinomas, cervix.
CERVICAL CANCER Worldwide, cervical cancer is twelfth most common and the fifth most deadly cancer in women. It affects about 16 per 100,000 women per year and kills about 9 per 100,000 per year. Cervical
More informationGynecologic Cancer InterGroup Cervix Cancer Research Network. Management of Cervical Cancer in Resource Limited Settings.
Management of Cervical Cancer in Resource Limited Settings Linus Chuang MD Conflict of Interests None Cervical cancer is the fourth most common malignancy in women worldwide 530,000 new cases per year
More informationECC or Margins Positive?
CLINICAL PRESENTATION This practice algorithm has been specifically developed for M. D. Anderson using a multidisciplinary approach and taking into consideration circumstances particular to M. D. Anderson,
More informationRisk Factors for Failing Cervical Cancer. Time of Simple Hysterectomy
Risk Factors for Failing Cervical Cancer Screening in Incidental Cervical Carcinoma at Time of Simple Hysterectomy Tara Castellano, MD Gynecologic Oncology Fellow Oklahoma Health Sciences Center, Stephenson
More informationUPDATE IN THE MANAGEMENT OF INVASIVE CERVICAL CANCER
UPDATE IN THE MANAGEMENT OF INVASIVE CERVICAL CANCER Susan Davidson, MD Professor Department of Obstetrics and Gynecology Division of Gynecologic Oncology University of Colorado- Denver Anatomy Review
More informationChapter 8 Adenocarcinoma
Page 80 Chapter 8 Adenocarcinoma Overview In Japan, the proportion of squamous cell carcinoma among all cervical cancers has been declining every year. In a recent survey, non-squamous cell carcinoma accounted
More informationRitu Salani, M.D., M.B.A. Assistant Professor, Dept. of Obstetrics & Gynecology Division of Gynecologic Oncology The Ohio State University
Cervical Cancer Ritu Salani, M.D., M.B.A. Assistant Professor, Dept. of Obstetrics & Gynecology Division of Gynecologic Oncology The Ohio State University Estimated gynecologic cancer cases United States
More informationCervical cancer presentation
Carcinoma of the cervix: Carcinoma of the cervix is the second commonest cancer among women worldwide, with only breast cancer occurring more commonly. Worldwide, cervical cancer accounts for about 500,000
More informationQuality Improvement Measures for Cervical Cytology Screening
Quality Improvement Measures for Cervical Cytology Screening Dr. Julie Baker-Townsend, DNP, FNP-BC, WHNP-BC Assistant Professor University of North Florida School of Nursing Jacksonville, Florida, U.S.A
More informationVagina. 1. Introduction. 1.1 General Information and Aetiology
Vagina 1. Introduction 1.1 General Information and Aetiology The vagina is part of internal female reproductive system. It is an elastic, muscular tube that connects the outside of the body to the cervix.
More informationPara-aortic laparoscopic lymph-node dissection for advanced cervical cancers
Para-aortic laparoscopic lymph-node dissection for advanced cervical cancers P. Mathevet, Hôpital Femme-Mère-Enfant, Bron Lymph-node involvement Is one of the major prognostic factor in gynecologic cancers.
More informationCARCINOMA CERVIX. Dr. PREETHI REDDY. B. M S OBG II yr POST GRADUATE.
CARCINOMA CERVIX Dr. PREETHI REDDY. B M S OBG II yr POST GRADUATE. Introduction Cervical cancer is the second most common female malignancy worldwide. It is responsible for 4,66,000 deaths annually worldwide
More informationPRINCESS MARGARET CANCER CENTRE CLINICAL PRACTICE GUIDELINES GYNECOLOGIC CANCER CERVIX
PRINCESS MARGARET CANCER CENTRE CLINICAL PRACTICE GUIDELINES GYNECOLOGIC CANCER CERVIX Site Group: Gynecology Cervix Author: Dr. Stephane Laframboise 1. INTRODUCTION 3 2. PREVENTION 3 3. SCREENING AND
More informationWhat is cervical cancer?
What is cervical cancer? The cervix is the bottom part, or neck, of the uterus. Cervical cancer happens when normal cells in the cervix change into abnormal cells, and grow out of control. Most women whose
More informationAdjuvant Therapies in Endometrial Cancer. Emma Hudson
Adjuvant Therapies in Endometrial Cancer Emma Hudson Endometrial Cancer Most common gynaecological cancer Incidence increasing in Western world 1-2% cancer deaths 75% patients postmenopausal 97% epithelial
More informationIndex. Surg Oncol Clin N Am 14 (2005) Note: Page numbers of article titles are in boldface type.
Surg Oncol Clin N Am 14 (2005) 433 439 Index Note: Page numbers of article titles are in boldface type. A Abdominosacral resection, of recurrent rectal cancer, 202 215 Ablative techniques, image-guided,
More informationGynecologic Malignancies. Kristen D Starbuck 4/20/18
Gynecologic Malignancies Kristen D Starbuck 4/20/18 Outline Female Cancer Statistics Uterine Cancer Adnexal Cancer Cervical Cancer Vulvar Cancer Uterine Cancer Endometrial Cancer Uterine Sarcoma Endometrial
More informationThe Pap Smear Test. The Lebanese Society of Obstetrics and Gynecology. Women s health promotion series
The Lebanese Society of Obstetrics and Gynecology Women s health promotion series The Pap Smear Test Since the Pap smear test started to be used the number of cases of cervical cancer was greatly reduced.
More informationHIV and AIDS Related Cancers DR GORDON AMBAYO UHS
HIV and AIDS Related Cancers DR GORDON AMBAYO UHS INTRODUCTION People with HIV/AIDS are at high risk for developing certain cancers, such as: Kaposi's sarcoma, non-hodgkin lymphoma, and cervical cancer.
More informationStaging. Carcinoma confined to the corpus. Carcinoma confined to the endometrium. Less than ½ myometrial invasion. Greater than ½ myometrial invasion
5 th of June 2009 Background Most common gynaecological carcinoma in developed countries Most cases are post-menopausal Increasing incidence in certain age groups Increasing death rates in the USA 5-year
More informationAlgorithms for management of Cervical cancer
Algithms f management of Cervical cancer Algithms f management of cervical cancer are based on existing protocols and guidelines within the ESGO comunity and prepared by ESGO Educational Committe as a
More informationNorth of Scotland Cancer Network Clinical Management Guideline for Carcinoma of the Uterine Cervix
THIS DOCUMENT North of Scotland Cancer Network Carcinoma of the Uterine Cervix UNCONTROLLED WHEN PRINTED DOCUMENT CONTROL Prepared by A Kennedy/AG Macdonald/Others Approved by NOT APPROVED Issue date April
More informationCervical Cancer 3/25/2019. Abnormal vaginal bleeding
Cervical Cancer Abnormal vaginal bleeding Postcoital, intermenstrual or postmenopausal Vaginal discharge Pelvic pain or pressure Asymptomatic In most patients who are not sexually active due to symptoms
More informationEstimated New Cancers Cases 2003
Harvard-MIT Division of Health Sciences and Technology HST.071: Human Reproductive Biology Course Director: Professor Henry Klapholz Estimated New Cancers Cases 2003 Images removed due to copyright reasons.
More informationRetrospective evaluation of clinical and pathological features, as well as diagnostic and treatment protocols of primary vaginal malignancy
ORIGINAL PAPER / GYNECOLOGY Ginekologia Polska 2016, vol. 87, no. 8, 541 545 Copyright 2016 Via Medica ISSN 0017 0011 DOI: 10.5603/GP.2016.0041 Retrospective evaluation of clinical and pathological features,
More informationMost common cancer Africans & Asians more prone because of poor socioeconomic condition Drastic decline in west as more detection of preinvasive
CANCER CERVIX Most common cancer Africans & Asians more prone because of poor socioeconomic condition Drastic decline in west as more detection of preinvasive leison by PAP Smears. Etiology: Age - 2 peaks
More informationKnowledge of Carcinoma Cervix among rural women of Reproductive age in Trichy district, India
Original Article Knowledge of Carcinoma Cervix among rural women of Reproductive age in Trichy district, India A.M Veerakumar. Assistant Professor, Community Medicine, Chennai Medical College Hospital
More informationRisk group criteria for tailoring adjuvant treatment in patients with endometrial cancer : a validation study of the GOG criteria
Risk group criteria for tailoring adjuvant treatment in patients with endometrial cancer : a validation study of the GOG criteria Suk-Joon Chang, MD, Hee-Sug Ryu MD Gynecologic Cancer Center Department
More information17 th ESO-ESMO Masterclass in clinical Oncology
17 th ESO-ESMO Masterclass in clinical Oncology Cervical and endometrial Cancer Cristiana Sessa IOSI Bellinzona, Switzerland Berlin, March 28 th, 2018 Presenter Disclosures None Cervical Cancer Estimated
More informationCervical cancer is a disease in which malignant (cancer) cells form in the tissues of the cervix.
Cervical Cancer Cervical cancer is a disease in which malignant (cancer) cells form in the tissues of the cervix. The cervix is the lower, narrow end of the uterus (the hollow, pear-shaped organ where
More informationEvolving Treatment Strategies for Cervical Cancer
Evolving Treatment Strategies for Cervical Cancer Nadeem Abu-Rustum, MD Memorial Sloan Kettering Cancer Center Evolving Treatment Strategies 1. Surgery 2. Radiation 3. Chemotherapy Incidence of cervix
More informationPromoting Cervical Screening Information for Health Professionals. Cervical Cancer
Promoting Cervical Screening Information for Health Professionals Cervical Cancer PapScreen Victoria Cancer Council Victoria 1 Rathdowne St Carlton VIC 3053 Telephone: (03) 635 5147 Fax: (03) 9635 5360
More informationPrognostic significance of positive lymph node number in early cervical cancer
1052 Prognostic significance of positive lymph node number in early cervical cancer JUNG WOO PARK and JONG WOON BAE Department of Obstetrics and Gynecology, Dong A University Hospital, Dong A University
More informationManagement of Cervical Cancer in Resource Limited Settings
Management of Cervical Cancer in Resource Limited Settings Linus Chuang MD MPH MS Professor, Gynecologic Oncology Icahn School of Medicine at Mount Sinai New York NY 84% of incidence and death occur in
More informationEndometrial Cancer. Saudi Gynecology Oncology Group (SGOG) Gynecological Cancer Treatment Guidelines
Saudi Gynecology Oncology Group (SGOG) Gynecological Cancer Treatment Guidelines Endometrial Cancer Emad R. Sagr, MBBS, FRCSC Consultant Gynecology Oncology Security forces Hospital, Riyadh Epidemiology
More informationPAP smear. (Papanicolaou Test)
PAP smear (Papanicolaou Test) Is a screening test to prevent/ detect cancerous processes in endocervical canal It reduces the mortality caused by cervical cancer up to 80% M. Arbyn; et al. (2010). "European
More informationVaginal intraepithelial neoplasia
Vaginal intraepithelial neoplasia The terminology and pathology of VAIN are analogous to those of CIN (VAIN I-III). The main difference is that vaginal epithelium does not normally have crypts, so the
More informationEvaluation the Correlation between Ki67 and 5 Years Disease Free Survival of Breast Cancer Patients
BIOSCIENCES BIOTECHNOLOGY RESEARCH ASIA, December 2015. Vol. 12(3), 2221-2225 Evaluation the Correlation between Ki67 and 5 Years Disease Free Survival of Breast Cancer Patients S.M. Hosseini¹, H. Shahbaziyan
More informationStaging and Treatment Update for Gynecologic Malignancies
Staging and Treatment Update for Gynecologic Malignancies Bunja Rungruang, MD Medical College of Georgia No disclosures 4 th most common new cases of cancer in women 5 th and 6 th leading cancer deaths
More informationProposed All Wales Vulval Cancer Guidelines. Dr Amanda Tristram
Proposed All Wales Vulval Cancer Guidelines Dr Amanda Tristram Previous FIGO staging FIGO Stage Features TNM Ia Lesion confined to vulva with
More informationDEPARTMENT OF ONCOLOGY ELECTIVE
DEPARTMENT OF ONCOLOGY ELECTIVE 2015-2016 www.uwo.ca/oncology Oncology Elective Program Administrator: Ms. Kimberly Trudgeon Room A4-901C (Admin) LHSC London Regional Cancer Centre (Victoria Campus) Phone:
More informationRESEARCH ARTICLE. Kuanoon Boupaijit, Prapaporn Suprasert* Abstract. Introduction. Materials and Methods
RESEARCH ARTICLE Survival Outcomes of Advanced and Recurrent Cervical Cancer Patients Treated with Chemotherapy: Experience of Northern Tertiary Care Hospital in Thailand Kuanoon Boupaijit, Prapaporn Suprasert*
More informationPap Smears Pelvic Examinations Well Woman Examinations. When should you have them performed???
Pap Smears Pelvic Examinations Well Woman Examinations. When should you have them performed??? Arlene Evans-DeBeverly, PA-C Copyright 2012 There are always ongoing changes in gynecology, including the
More informationJanjira Petsuksiri, M.D
GYN malignancies Janjira Petsuksiri, M.D Outlines Cervical cancer Endometrial cancer Ovarian cancer Vaginal cancer Vulva cancer 2 CA Cervix Epidemiology - Second most common female cancer Risk factors
More informationIs Ovarian Preservation Feasible in Early-Stage Adenocarcinoma of the Cervix?
e-issn 1643-3750 DOI: 10.12659/MSM.897291 Received: 2015.12.27 Accepted: 2016.01.13 Published: 2016.02.08 Is Ovarian Preservation Feasible in Early-Stage Adenocarcinoma of the Cervix? Authors Contribution:
More informationCoversheet for Network Site Specific Group Agreed Documentation
Coversheet for Network Site Specific Group Agreed Documentation This sheet is to accompany all documentation agreed by Pan Birmingham Cancer Network Site Specific Groups. This will assist the Network Governance
More informationRole and Techniques of Surgery in Carcinoma Cervix. Dr Vanita Jain Additional Professor OBGYN PGIMER, Chandigarh
Role and Techniques of Surgery in Carcinoma Cervix Dr Vanita Jain Additional Professor OBGYN PGIMER, Chandigarh Points for Discussion Pattern of spread Therapeutic options Types of surgical procedures
More informationPrevention, Diagnosis and Treatment of Gynecologic Cancers
Prevention, Diagnosis and Treatment of Gynecologic Cancers Jubilee Brown MD and Pamela T. Soliman MD, MPH Department of Gynecologic Oncology and Reproductive Medicine University of Texas MD Anderson Cancer
More informationChapter 2: Initial treatment for endometrial cancer (including histologic variant type)
Chapter 2: Initial treatment for endometrial cancer (including histologic variant type) CQ01 Which surgical techniques for hysterectomy are recommended for patients considered to be stage I preoperatively?
More informationMichael G. Kelly, MD Gynecologic Oncologist University of Colorado Cancer Center
Michael G. Kelly, MD Gynecologic Oncologist University of Colorado Cancer Center 50 yo healthy postmenopausal female with BMI = 35 with screening PAP smear = AGUS. What is the next step? (1) Colposcopy
More informationMANAGEMENT OF CERVICAL CANCER
MANAGEMENT OF CERVICAL CANCER Dr. Ujeen Shrestha Malla* and Prof. Dr. Zhang Shui Rong Department of Obstetrics and Gynaecology, Clinical Medical College of Yangtze University, Jingzhou Central Hospital,
More informationGynecologic Oncology Level: PGY-4
Gynecologic Oncology Level: PGY-4 Service: Oncology Length of Rotation: 4 months Supervision: PGY-4 Resident Oncology Faculty All resident activity is directly supervised by the attending physician assigned
More informationInvasive Cervical Cancer: Squamous Cell, Adenocarcinoma, Adenosquamous
Note: If available, clinical trials should be considered as preferred treatment options for eligible patients (www.mdanderson.org/gynonctrials). Other co-morbidities are taken into consideration prior
More informationENDOMETRIAL CANCER. Endometrial cancer is a great concern in UPDATE. For personal use only. Copyright Dowden Health Media
For mass reproduction, content licensing and permissions contact Dowden Health Media. UPDATE ENDOMETRIAL CANCER Are lymphadenectomy and external-beam radiotherapy valuable in women who have an endometrial
More informationDepartment of Pathology, Kathmandu Medical College & Teaching Hospital, Sinamangal, Kathmandu, Nepal
Kathmandu University Medical Journal (2007), Vol. 5, No. 4, Issue 20, 461-467 Original Article Correlation of PAP smear findings with clinical findings and cervical biopsy Pradhan B 1, Pradhan SB 2, Mital
More informationMRI in Cervix and Endometrial Cancer
28th Congress of the Hungarian Society of Radiologists RCR Session Budapest June 2016 MRI in Cervix and Endometrial Cancer DrSarah Swift St James s University Hospital Leeds, UK Objectives Cervix and endometrial
More informationStudy of incidence and different aspects of cervical malignancy in tertiary centre of Jharkhand, India
International Journal of Reproduction, Contraception, Obstetrics and Gynecology Bijeta et al. Int J Reprod Contracept Obstet Gynecol. 2017 Jul;6(7):3118-3123 www.ijrcog.org DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20172945
More informationANAL CANCER Updated May 2016 by Dr. Daniel Yokom (PGY-5 Medical Oncology Resident, University of Toronto)
ANAL CANCER Updated May 2016 by Dr. Daniel Yokom (PGY-5 Medical Oncology Resident, University of Toronto) Reviewed by Dr. Lee-Ying (Staff Medical Oncologist, University of Calgary), Dr. Kzyzanowska (Staff
More informationARROCase: Locally Advanced Endometrial Cancer
ARROCase: Locally Advanced Endometrial Cancer Charles Vu, MD (PGY-3) Faculty Advisor: Peter Y. Chen, MD, FACR Beaumont Health (Royal Oak, MI) November 2016 Case 62yo female with a 3yr history of vaginal
More informationAn Unusual Case of Cervical Cancer with Inguinal Lymph Node Metastasis: A Case Report and Review of the Literature
Archives of Clinical and Medical Case Reports doi: 10.26502/acmcr.9655003 Volume 1, Issue 1 Case Report An Unusual Case of Cervical Cancer with Inguinal Lymph Node Metastasis: A Case Report and Review
More informationGynecology Oncology Rotation
McGill University Obstetrics and Gynecology Residency Program Goals and Objectives Gynecology Oncology Rotation Overview Goal The primary goal of the resident s Gynecology Oncology rotation of 4 weeks
More informationFact about Cervical Cancer
Cervical Cancer Fact about Cervical Cancer Approximately 500,000 deaths linked to Cancer in US every year (Singh-Cundy and Cain 261) Nearly all cases are linked to HPV (Savard) All women are at risk Sexually
More informationCervical Cancer Guidelines L and SC Network July Introduction:
Cervical Cancer Guidelines L and SC Network July 2018 Introduction: There was a total number of 442 cases of cervix cancer diagnosed in Lancashire and South Cumbria Cancer Network in the period 2005 2009
More informationCervical Screening for Dysplasia and Cancer in Patients with HIV
Cervical Screening for Dysplasia and Cancer in Patients with HIV Adult Clinical Guideline from the New York State Department of Health AIDS Institute w w w.hivg uidelines.org Purpose of the Guideline Increase
More informationNew Cancer Cases By Site Breast 28% Lung 14% Colo-Rectal 10% Uterus 6% Thyroid 5% Lymphoma 4% Ovary 3%
Uterine Malignancy New Cancer Cases By Site 2010 Breast 28% Lung 14% Colo-Rectal 10% Uterus 6% Thyroid 5% Lymphoma 4% Ovary 3% Cancer Deaths By Site 2010 Lung 26% Breast 15% Colo-Rectal 9% Pancreas 7%
More informationGynecologic Cancers. What is Gynecologic Cancer. Who is at risk for GYN cancer? 3/1/2018 1
What is Gynecologic Cancer Gynecologic Cancers Marge Ramsdell RN, MN, OCN Madigan Army Medical Center Any cancer that starts in a woman s reproductive organs Each GYN cancer is unique 5 main types Cervical
More informationCase Report A Case of Malignant Melanoma of the Uterine Cervix with Disseminated Metastases throughout the Vaginal Wall
Hindawi Case Reports in Obstetrics and Gynecology Volume 2017, Article ID 5656340, 4 pages https://doi.org/10.1155/2017/5656340 Case Report A Case of Malignant Melanoma of the Uterine Cervix with Disseminated
More informationChapter 5 Stage III and IVa disease
Page 55 Chapter 5 Stage III and IVa disease Overview Concurrent chemoradiotherapy (CCRT) is recommended for stage III and IVa disease. Recommended regimen for the chemotherapy portion generally include
More informationCervixcancer. Vad är aktuellt? Jan Persson. Lund. Docent överläkare Dep of OB&G Skane univ hosp Lund Sweden
Cervixcancer Copyright Jan Persson Lund Vad är aktuellt? Jan Persson Docent överläkare Dep of OB&G Skane univ hosp Lund Sweden Controversies Preop selection related stage ( stage 1b1>= 2 cm) Neoadjuvant
More informationFocus on Cervical Cancer: Key Messages. Cancer System Quality Index 2016
Focus on Cervical Cancer: Key Messages Cancer System Quality Index 2016 A first look at cervical cancer across the care continuum Cervical cancer starts in the cells of the cervix. The cervix is the lower
More informationShrestha P CORRESPONDENCE
NJOG 2015 Jul-Dec; 20 (2):45-49 Original Article Shrestha P 1 2 2 1 Department of Obstetrics and Gynecology, Patan Academy of Health Science, Lalitpur, 2 Department of Obstetrics and Gynecology, Tribhuvan
More informationObjectives. Background. Background. Background. Background 9/26/16. Update on Cervical and HPV Screening Guidelines: To pap or not to pap?
Update on Cervical and HPV Screening Guidelines: To pap or not to pap? Marina Delazari Miller MD Clinical Assistant Professor Department of Obstetrics & Gynecology University of Iowa Hospitals and Clinics
More informationIndex. B Bilateral salpingo-oophorectomy (BSO), 69
A Advanced stage endometrial cancer diagnosis, 92 lymph node metastasis, 92 multivariate analysis, 92 myometrial invasion, 92 prognostic factors FIGO stage, 94 histological grade, 94, 95 histologic cell
More informationWhat women should know about. cervical cancer. American Cancer Society Guidelines for the Early Detection of Cervical Cancer
What women should know about cervical cancer American Cancer Society Guidelines for the Early Detection of Cervical Cancer One of the best things you can do so you don t get cervical cancer is get regular
More informationRESEARCH ARTICLE. Abstract. Introduction
DOI:http://dx.doi.org/10.7314/APJCP.2013.14.11.6935 Prognostic Model in Patients with Early-stage Squamous Cell Carcinoma of the Uterine Cervix RESEARCH ARTICLE Prognostic Model in Patients with Early-stage
More informationCase Scenario 1. History
History Case Scenario 1 A 53 year old white female presented to her primary care physician with post-menopausal vaginal bleeding. The patient is not a smoker and does not use alcohol. She has no family
More informationOne of the commonest gynecological cancers,especially in white Americans.
Gynaecology Dr. Rozhan Lecture 6 CARCINOMA OF THE ENDOMETRIUM One of the commonest gynecological cancers,especially in white Americans. It is a disease of postmenopausal women with a peak incidence in
More informationClinical statistics of gynecologic cancers in Japan
J Gynecol Oncol. 2017 Mar;28(2):e32 pissn 2005-0380 eissn 2005-0399 Review Article Clinical statistics of gynecologic cancers in Japan Wataru Yamagami, 1,7 Satoru Nagase, 2,7 Fumiaki Takahashi, 3 Kazuhiko
More informationWhat is a Pap smear?
Pap smear What is a Pap smear? A Pap smear is a test that checks for changes in the cells of your cervix. The cervix is the lower part of the uterus that opens into the vagina. Developed over forty years
More informationFREQUENCY AND RISK FACTORS OF CERVICAL Human papilloma virus INFECTION
Arch. Biol. Sci., Belgrade, 66 (4), 1653-1658, 2014 DOI:10.2298/ABS1404653M FREQUENCY AND RISK FACTORS OF CERVICAL Human papilloma virus INFECTION IN WOMEN IN MONTENEGRO GORDANA MIJOVIĆ 1, TATJANA JOVANOVIĆ
More informationA Review on Role of Human Papilomma Virus (HPV) In Cervical Cancer
21 Review Article A Review on Role of Human Papilomma Virus (HPV) In Cervical Cancer M.Sushma*, B.Vamsikrishna, M. Babu, R. Mohanraj Department of Pharmacy Practice, Raghavendra Institute of Pharmaceutical
More informationHPV the silent killer, Prevention and diagnosis
HPV the silent killer, Prevention and diagnosis HPV Human Papilloma Virus is a name given for a silent virus transmitted sexually most of the time, a virus that spreads in the name of love, passion, and
More informationAnalysis of Prognosis and Prognostic Factors of Cervical Adenocarcinoma and Adenosqumous Carcinoma of the Cervix
DOI 10.1007/s11805-009-0133-8 133 Analysis of rognosis and rognostic Factors of Cervical Adenocarcinoma and Adenosqumous Carcinoma of the Cervix Guangwen Yuan Lingying Wu Xiaoguang Li Manni Huang Department
More informationFacing a Hysterectomy? If you ve been diagnosed with gynecologic cancer, learn about minimally invasive da Vinci Surgery
Facing a Hysterectomy? If you ve been diagnosed with gynecologic cancer, learn about minimally invasive da Vinci Surgery The Surgery: Hysterectomy If you have gynecologic cancer - such as cancer of the
More informationChallenges and successes with cervical cancer early detection and treatment in Kenya
Challenges and successes with cervical cancer early detection and treatment in Kenya Omenge Orangó MD Chair, Department of Reproductive Health and Divisional Head of Gynecologic Oncology, Moi University
More informationCPC on Cervical Pathology
CPC on Cervical Pathology Dr. W.K. Ng Senior Medical Officer Department of Clinical Pathology Pamela Youde Nethersole Eastern Hospital Cervical Smear: High Grade SIL (CIN III) Cervical Smear: High Grade
More informationA phase II study of weekly paclitaxel and cisplatin followed by radical hysterectomy in stages IB2 and IIA2 cervical cancer AGOG14-001/TGOG1008
A phase II study of weekly paclitaxel and cisplatin followed by radical hysterectomy in stages IB2 and IIA2 cervical cancer AGOG14-001/TGOG1008 NCT02432365 Chyong-Huey Lai, MD On behalf of Principal investigator
More informationABSTRACT. Methods: A cross sectional study was carried out using questionnaires administered to female nurses and doctors
Knowledge, Attitudes and Practice regarding personal cervical cancer screening among Clinical Staff Working in Obstetrics and Gynaecology at Two Tertiary Institutions in Jamaica L Campbell 1 G Reynolds
More informationCERVICAL CANCER: A GUIDE FOR PATIENTS
CERVICAL CANCER: A GUIDE FOR PATIENTS PATIENT INFORMATION BASED ON ESMO CLINICAL PRACTICE GUIDELINES This guide for patients has been prepared by Reliable Cancer Therapies (RCT) as a service to patients,
More informationOpinion: Cervical cancer a vaccine preventable disease
Opinion: Cervical cancer a vaccine preventable disease Leon Snyman Principal specialist at the Department of Obstetrics and Gynaecology, Gynaecological Oncology unit, University of Pretoria and Kalafong
More informationPRINCESS MARGARET CANCER CENTRE CLINICAL PRACTICE GUIDELINES GYNECOLOGIC CANCER VULVAR
PRINCESS MARGARET CANCER CENTRE CLINICAL PRACTICE GUIDELINES GYNECOLOGIC CANCER VULVAR Last Revision Date July 2015 1 Site Group: Gynecologic Cancer Vulvar Author: Dr. Stephane Laframboise 1. INTRODUCTION
More informationEpidemiologic characteristics of cervical cancer in Korean women
Review Article J Gynecol Oncol Vol. 25, No. 1:70-74 pissn 2005-0380 eissn 2005-0399 Epidemiologic characteristics of cervical cancer in Korean women Hyun-Joo Seol, Kyung-Do Ki, Jong-Min Lee Department
More informationWhat is Cervical Cancer?
What is Cervical Cancer? Cervical cancer starts in a woman's cervix, the lower narrow part of the uterus. The uterus holds the growing fetus during pregnancy. The cervix connects the lower part of the
More informationCervical Cancer: 2018 FIGO Staging
Cervical Cancer: 2018 FIGO Staging Jonathan S. Berek, MD, MMS Laurie Kraus Lacob Professor Stanford University School of Medicine Director, Stanford Women s Cancer Center Senior Scientific Advisor, Stanford
More informationUTERINE SARCOMAS CURRENT THERAPEUTIC OPTIONS
Review Journal of Translational Medicine and Research, volume 19, no. 1-2, 2014 UTERINE SARCOMAS CURRENT THERAPEUTIC OPTIONS N. Bacalbaæa 1, A. Traistaru 2, I. Bãlescu 3 1 Carol Davila University of Medicine
More informationPrevent You can prevent cancer of the cervix
Follow the PAP Strategy Plan Act Plan to have a Pap Test Make an appointment with your doctor Prevent You can prevent cancer of the cervix Learning Objectives To know what a Pap test is and why it is important
More informationRisk factors for precancerous lesions of the cervix in a population of Georgian women
Training Course in Sexual and Reproductive Health Research Geneva, 2 March 2009 Risk factors for precancerous lesions of the cervix in a population of Georgian women Maia Chiokadze, M.D. Medical Diagnostic
More informationBCCR. Validity and Reliability of the Knowledge, Attitude and Practice (KAP) Questionnaire about Cervical Cancer and its Screening among Iranian Women
ORIGINAL ARTICLE Validity and Reliability of the Knowledge, Attitude and Practice (KAP) Questionnaire about Cervical Cancer and its Screening among Iranian Women Mahnoosh Khosravi 1,Sareh Shafaee 2,ALaleh
More information6 Week Course Agenda. Today s Agenda. Ovarian Cancer: Risk Factors. Winning the War 11/30/2016 on Women s Cancer Gynecologic Cancer Prevention
6 Week Course Agenda Winning the War 11/30/2016 on Women s Cancer Gynecologic Cancer Prevention Lee-may Chen, MD Director, Division of Gynecologic Oncology Professor Department of Obstetrics, Gynecology
More information