Role of Dietary Fats and Cardiovascular Risk
|
|
- Moses Henderson
- 6 years ago
- Views:
Transcription
1 Role of Dietary Fats and Cardiovascular Risk Julie Lovegrove Hugh Sinclair Unit of Human Nutrition & Institute for Cardiovascular and Metabolic Research University of Reading, UK Alpro Student Symposium 24 th October 2017 University of Reading
2 Leading cause of global deaths Heart & Circulatory Disorders WHO. Global Health Estimates: Deaths by Cause, Age, Sex and Country, Geneva, WHO,
3 Dietary fat recommendations Nutrient Total fat < 33 % Saturated fat < 10 % UK (% total energy) Polyunsaturated fat 0.2% - 10% Monounsaturated fat 12% EPA/DHA > 0.45 g Trans fat < 2 % X X currently assessing saturated fat guidance 3
4 SFA GUIDANCE MET BY ONLY 11% COUNTRIES ID = Indonesia; BE = Belgium; DK = Denmark; SI = Slovenia; AT = Austria; DE = Germany; CM = Cameroon; FR = France; RU = Russia; IE = Ireland; FI = Finland; NL = Netherlands; GR = Greece; NZ = New Zealand; CZ = Czech Republic; SK = Slovakia; AU = Australia; SE = Sweden; BG = Bulgaria; NO = Norway; ES = Spain; UK = United Kingdom; PL = Poland; SG = Singapore; US = United States; HU = Hungary; IT = Italy; CA = Canada; MY = Malaysia; MX = Mexico; GT = Guatemala; IL = Israel; PT = Portugal; ZA = South Africa; JP = Japan; HK = Hong Kong; IN = India; KP = South Korea; CN = China; BD =Bangladesh. Harika et al., Ann Nutr Metab. 2013;63;229 4
5 CONFUSION OVER SATURATES GUIDANCE 5
6 6
7 Relative risk for coronary outcomes for SFA intake - Meta-analysis of prospective cohort studies Reduced risk higher intake Increased risk higher intake ++ corrected for lipid Chowdhury et al., Annals of Internal Medicine. 2014:160;
8 Hierarchy of Scientific Evidence HIGH Level of evidence Meta-analysis Randomly Controlled Trials (RCTs) Prospective Cohort Trials Prevalence Studies Ecological (cross-cultural) Studies Evidence based medicine Epidemiology LOW Animal Studies 8
9 SFA reduction vs usual diet on CVD events - Meta-analysis of randomised control trials Reduced risk low SFA Increased risk low SFA Hooper et al. Cochrane Library. 2015, Issue 6 CD
10 Dietary manipulation is complex! 10
11 Saturation fat substitution with carbohydrates and unsaturated fat Saturated with polyunsaturated fat Saturated fat with carbohydrates 26% lower risk Reduced risk Increased risk Reduced risk Increased risk Substitution of saturated for polyunsaturated fats significantly reduces hazard ratios for coronary deaths Jakobson M et al. Am. J. Clin. Nutr. 2009:89;
12 Change in CHD associated with isocaloric substitution of dietary components Substitution of SFA Nurses Health Study (84,628) and Health Professionals Follow-up (42,908) years of follow-up (FFQ every 4 years) Li et al. J Am Coll Cardiol 2015;66:
13 Sources of unsaturated fats Polyunsaturated fats cis PUFA cis n-3 PUFA (alpha linolenic acid) cis n-6 PUFA (linoleic acid) Long chain cis n-3 PUFA (eicosapentaenoic acid docosahexaenoic acid) 13
14 Sources of unsaturated fats Polyunsaturated fats cis PUFA cis n-6 PUFA (linoleic acid) 14
15 Linoleic acid associated with lower CHD 0.79 (0.71, 0.89) Favours Linoleic acid Farvid et al., Circulation. 2014:130;
16 Sources of unsaturated fats Polyunsaturated fats cis PUFA cis n-3 PUFA (alpha linolenic acid) 16
17 Alpha linolenic associated with lower risk CVD Dietary ALNA intake Biomarker ALNA intake Overall 0.86 (0.77, 0.97) 100 Pan et al., AJCN 2012;96: Higher ALNA associated with a moderately lower risk CVD (1g/day increase in ALNA associated with 10% lower risk CAD death) 17
18 Sources of unsaturated fats Polyunsaturated fats cis PUFA Long chain cis n-3 PUFA (eicosapentaenoic acid docosahexaenoic acid) 18
19 Regular fish or LC n-3 PUFA reduces CVD Total mortality CVD ~20% reduction in relative risk CHD death CHD Mozzaffarian & Wu., JACC. 2011:58; Reduced risk Increased risk 19
20 Sources of unsaturated fats Monounsaturated fats cis MUFA Oleic acid Oleic acid 20
21 Relative risk for coronary outcomes for MUFA intake - Meta-analysis of prospective cohort studies Reduced risk higher intake Increased risk higher intake ++ corrected for lipid Chowdhury et al., Annals of Internal Medicine. 2014:160;
22 Pooled RR for combined CVD events (top vs bottom tertile) MUFA MUFA: 0.95 (0.89, 1.02) P = 0.14 MUFA:SFA ratio MUFA:SFA: 0.93 (0.86, 1.01) P = 0.07 Olive oil Olive oil: 0.72 (0.57, 0.91) P = Oleic acid OVERALL Oleic acid: 0.87 (0.76, 1.00) P = 0.04 Overall: 0.91 (0.86, 0.96) P = Schwingshackl and Hoffmann Lipids in Health and Disease 2014, 13:154 22
23 Med diet & incidence of composite CVD endpoints Predimed study 7447 participants (288 events) years 4 year follow-up Group: a. MD & virgin olive oil (1l/wk) b. MD & nuts (30g/d) c. Low fat diet No change in activity or weight Years Estruch R et al (2013) New Engl J Med 368,
24 Sources of unsaturated fats Trans unsaturated fatty acids trans Industrial trans t-elaidic acid Ruminant trans t-vaccenic acid t-palmitoleic acid 24
25 Relative risk of CHD with trans fat intake Risk of CHD Risk of CHD Little impact on CHD risk at current mean UK dietary intakes BUT important to minimise TFA in food chain and monitor intake Trans fatty acid intake (g/day) UK Women (2017) (0.7 %E, 1.2 g/day) UK Men (2017) (0.7 %E, 1.6 g/day) SACN. Update on trans fatty acids report
26 RR of total, industrial & ruminant TFA on mortality Total TFA Industrial TFA Ruminant TFA Trans fats are associated with all cause mortality, total CHD, and CHD mortality probably due to i-trans de Souza et al. BMJ 2015;101h;
27 Macronutrients & CVD mortality PURE study. 18 non-western countries (n=135,335 men and women. 7.4 yrs follow-up) No association between between macronutrients and CVD SFA (%E) MUFA (9%E) PUFA (%E) CARB (%E) <10%E 45-50%E Dehghan et al., PURE study. Lancet 29 Aug [online] 27
28 CVD Risk Factors Obesity Gender Raised LDL chol Genetic determination Raised blood pressure Ethnicity Raised triacylglycerol Age Diabetes Menopausal status Vascular function Inflammation DIET Smoking Alcohol Physical activity Non-modifiable Stress Modifiable Lifestyle 28
29 Blood Cholesterol Coronary Heart Disease LDL-cholesterol 29
30 MUFA & carbohydrate replacement of SFA - RCT SFA MUFA Carbohydrate 0,2 0,1 0 n = month 0,1 0, ,3 0, LDL-C TC:HDL-C Jebb et al, Am J Clin Nutr. 2010;92:
31 MUFA & n-6 PUFA replacement of SFA - RCT 0,3 SFA rich diet MUFA rich diet SFA MUFA PUFA TC:HDL C change from baseline 0,2 0,1 0 0,1 0,2 *** ** ** *** n = months 0,3 TC:HDL LDL:HDL Vafeiadou et al, Am J Clin Nutr 2015:102:
32 Predicted change in plasma lipids with replacement of dietary carbohydrates Micha & Mozzaffarin. Lipids 2010:45;
33 Risks leading to death 33
34 MUFA & n-6 PUFA replacement of SFA - RCT SFA MUFA PUFA Absolute difference in mean night SBP (mmhg) 6,0 5,0 4,0 3,0 2,0 1,0 0,0 1,0 Appel L J et al. Hypertension 2006;47: ,0 3,0 * Overall time x treatment P=0.019 n = months Vafeiadou et al, Am J Clin Nutr 2015:102:
35 Importance of food based recommendations versus Nutrients Whole Foods 35
36 Impact of replacing 10% US dietary fat Mensink et al., Am J Clin Nutr 2003:1146;55. 36
37 Contribution of foods to SFA in UK diet Milk & milk products 24% Butter 6% NDNS (2016) 37
38 Effect of SFA food source on CVD risk Multi-ethnic Study of Atherosclerosis (MESA) Years Follow-up MEAT FAT +5g/d +5% of energy +48% DAIRY FAT +26% CVD RISK +5g/d +5% of energy -21% -38% de Oliveira Otto et al., Am J Clin Nutr 2012;96:
39 RR of CVD for every 244g/d milk intake 1.01 (0.93, 1.10) / 244g/d Guo et al., Eur. J Epidemiol. 2017:32;
40 RR of CVD for every 20 g/d of fermented dairy 0.97 (0.97, 0.99) / 244g/d Guo et al., Eur. J Epidemiol. 2017:32;
41 Dairy potential mechanisms Potential mechanisms for dairy Blood pressure Bioactive Magnesium, peptides Potassium and Calcium Ma, K and Ca Bioactive peptides Peptides Minerals Regulation van Meijl et al. (2008) Nutr Res Rev; Turpeinen et al. (2004) Annals of Medicine FitzGerald et al. (2004) J Nutr;134:980S-988S. Arterial stiffness Similar to blood pressure? L-arganine precursor of nitric oxide? Similar to blood pressure? 41
42 Conclusions Replacement of SFA with PUFA reduces CHD mortality and risk factors Replacement of SFA with MUFA reduces CVD risk factors Increased LC n-3 PUFA associated with reduction in CHD mortality and CVD risk factors Benefit in mini-mising itfa intake for reduction in CHD risk Different fat-rich foods impacts on response to fats 42
43 ACKNOWLEDGEMENTS 43
44 44
45 THANK YOU 45
46 LDL-chol after consumption of ~80 g/d fat (~36g/d SFA) as cheese or butter Cheese vs butter Hjerpsted et al. Am J Clin Nutr 2011;94:
47 Dose response and time course for altering clinical events from fish and fish oil Mozaffarian D & Rimm EB. JAMA. 2006:296;
Fatty acids, cardiovascular disease and diabetes
Fatty acids, cardiovascular disease and diabetes Rajiv Chowdhury, Nita Forouhi 28 th October 2015 Workshop on nutritional biomarkers A joint PHRI/MRC Epidemiology Unit Initiative Population nutrient goal
More informationDietary Reference Values: a Tool for Public Health
HOGE GEZONDHEISRAAD Dietary Reference Values: a Tool for Public Health CONSEIL SUPERIEUR DE LA SANTE Belgian Dietary Reference Values for Energy and Macronutrients: FATS G. De Backer Brussels, February
More informationDiet and Non-Communicable Diseases (NCDs): latest evidence
Diet and Non-Communicable Diseases (NCDs): latest evidence Fumiaki Imamura, MS, PhD fumiaki.imamura@mrc-epid.cam.ac.uk 23 Nov 2016, London publications in our field N journals=436 N publications: 90000
More informationCan foods change your health? Good fats and bad fats: what is the evidence? Kay-Tee Khaw. Main categories of fats
Can foods change your health? Good fats and bad fats: what is the evidence? Kay-Tee Khaw UNIVERSITY OF CAMBRIDGE Hong Kong July 6 213 Yerushalmy J Hilleboe HE NY State J Med 1957 Coronary heart disease
More informationFATS The Facts. compiled by the Nestlé Research Center
FATS The Facts compiled by the Nestlé Research Center Dietary fats are a public health concern Dietary fats are necessary for ensuring optimal health. Recent dietary guidelines focus on fat quality and
More informationFatty acids and cardiovascular health: current evidence and next steps
Fatty acids and cardiovascular health: current evidence and next steps Emanuele Di Angelantonio, MD, PhD Department of Public Health and Primary Care NICE guidelines on fatty acids Eliminate the use of
More informationUNIVERSITY OF CAMBRIDGE. Fatty acids and heart disease. Kay-Tee Khaw
UNIVERSITY OF CAMBRIDGE Fatty acids and heart disease Kay-Tee Khaw Bristol 3 October 2013 Yerushalmy J Hilleboe HE NY State J Med 1957 Coronary heart disease death rates in relation to blood cholesterol
More informationHealthy Fats & Fatty Acids Current Dietary Recommendations and Popular Opinions
Healthy Fats & Fatty Acids Current Dietary Recommendations and Popular Opinions Presentation 1 of 2 Penny M. Kris-Etherton PhD RD FAHA FNLA FASN CLS Department of Nutritional Sciences Penn State University
More informationProven and Proposed Cardiovascular Benefits of Soyfoods
Proven and Proposed Cardiovascular Benefits of Soyfoods Mark Messina, PhD, MS Soy Nutrition Institute Loma Linda University Nutrition Matters, Inc. markjohnmessina@gmail.com Alpro Foundation 20 years symposium
More informationFacts on Fats. Ronald P. Mensink
Facts on Fats Ronald P. Mensink Department of Human Biology NUTRIM, School for Nutrition, Toxicology and Metabolism Maastricht University Maastricht The Netherlands Outline of the Presentation Saturated
More informationTraditional Asian Soyfoods. Proven and Proposed Cardiovascular Benefits of Soyfoods. Reduction (%) in CHD Mortality in Eastern Finland ( )
Proven and Proposed Cardiovascular Benefits of Soyfoods Mark Messina, PhD, MS Soy Nutrition Institute Loma Linda University Nutrition Matters, Inc. markjohnmessina@gmail.com 1000 80 20 60 40 40 60 20 80
More informationCardiovascular risk potential of dietary saturated fats: an update and some implications
Cardiovascular risk potential of dietary saturated fats: an update and some implications Gerard Hornstra, PhD Med" Prof. Em. of Experimental Nutrition" Maastricht University" The Netherlands" Cardiovascular
More informationDietary priorities for type 2 diabetes
Dietary priorities for type 2 diabetes Edinburgh, 17 th July 2018 Nita Gandhi Forouhi MRC Epidemiology Unit, University of Cambridge MRC Epidemiology Unit World Congress on Prevention of Diabetes and its
More informationEU Market Situation for Poultry. Committee for the Common Organisation of the Agricultural Markets 20 April 2017
EU Market Situation for Poultry Committee for the Common Organisation of the Agricultural Markets 2 April 217 -9.% -11.% -5.% -.1% -.7% -2.2% 3.% 1.7% 1.2%.8%.6%.%.%.% 7.9% 7.% 6.4% 6.2% 6.% 5.5% 5.3%
More informationGoing Coconut over Saturated Fat? Why So Much Confusion? Part 1 Interpreting Conflicting Research
Going Coconut over Saturated Fat? Why So Much Confusion? Part 1 Interpreting Conflicting Research Disclosures Alice H Lichtenstein Board Member/Advisory Panel Food and Nutrition Board, National Academies
More informationThe impact of dairy products on cardiovascular health
The impact of dairy products on cardiovascular health D Vasilopoulou 2014 1 Overview CVD mortality in UK Does dairy consumption increase the risk of CVD? Dairy intake as part of healthy lifestyle RESET
More informationImpact of trans fats on health EFSA s work related to trans Fatty acids
Setting the scene Impact of trans fats on health EFSA s work related to trans Fatty acids Prof. Ambroise Martin Member of the EFSA WG on DRVs (former chair 2006-2015) and NDA Panel 2006-2015 (former chair
More informationPattern of lipid biomarkers and risk of cardiovascular disease
Pattern of lipid biomarkers and risk of cardiovascular disease Robert Clarke Clinical Trial Service Unit University of Oxford 9 January 2017 Biomarkers for dietary fats Blood lipids (LDL, HDL, triglycerides,
More informationThe Mediterranean Diet: The Optimal Diet for Cardiovascular Health
The Mediterranean Diet: The Optimal Diet for Cardiovascular Health Vasanti Malik, ScD Research Scientist Department of Nutrition Harvard School of Public Health Cardiovascular Disease Prevention International
More informationMilk and Dairy for Cardiometabolic Health
Milk and Dairy for Cardiometabolic Health Anne Mullen, BSc, PhD, FHEA, RD Director of Nutrition at The Dairy Council November 2016 Email: a.mullen@dairycouncil.org.uk Tel: 020 7025 0560 Web: www.milk.co.uk
More informationCardiac patient quality of life. How to eat adequately?
Cardiac patient quality of life How to eat adequately? François Paillard CV Prevention Center CHU Rennes JESFC, Paris, 17/01/2013 Mrs. L. 55 yrs, Coronary artery disease, normal weight, mild hypertension
More informationOverview. The Mediterranean Diet: The Optimal Diet for Cardiovascular Health. No conflicts of interest or disclosures
The Mediterranean Diet: The Optimal Diet for Cardiovascular Health No conflicts of interest or disclosures Vasanti Malik, ScD Research Scientist Department of Nutrition Harvard School of Public Health
More information13/09/2012. Dietary fatty acids. Triglyceride. Phospholipids:
CARDIOVASCULAR DISEASES (CVD) and NUTRITION Major cause of morbidity & mortality in Canada & other developed countries e.g., majority of approved health claims on food labels relate to lowering CVD Relation
More informationModifying effects of dietary polyunsaturated fatty acid (PUFA) on levels of cholesterol and their implications for heart health
Modifying effects of dietary polyunsaturated fatty acid (PUFA) on levels of cholesterol and their implications for heart health Robert Clarke Clinical Trial Service Unit University of Oxford 28 th May
More informationDairy Intake and Risk Factors for Chronic Disease
Dairy Intake and Risk Factors for Chronic Disease Seminar, Nutrition 566-1 Amber Brouillette Hannah Griswold LETS TAKE A POLL Claims for Dairy Consumption Unnatural Claims Against Cancer development High
More informationDairy matrix effects on T2 diabetes and cardiometabolic health?
Department of Nutrition, Exercise and Sports Dairy matrix effects on T2 diabetes and cardiometabolic health? Arne Astrup Head of department, professor, MD, DMSc. Department of Nutrition, Exercise and Sports
More informationWhat should I eat? I am so confused. Jennifer Lyon DO
What should I eat? I am so confused. Jennifer Lyon DO Conflict of Interest Disclosure I have no conflict of interest to report Overview 2015-2020 Dietary Guidelines 5 primary guidelines Sugar intake Sodium
More informationSaturated Fats: What is the Link to Cardiovascular Disease?
Saturated Fats: What is the Link to Cardiovascular Disease? Benoît Lamarche, PhD Chair of Nutrition School of Nutrition INAF, Université Laval Québec, Canada CNS 2015 Winnipeg Disclosures Funding (last
More informationNutrition Counselling
Nutrition Counselling Frieda Dähler Augustiny, Nutritional Counsellor Preventive Cardiology & Sports Medicine University Clinic of Cardiology Optimal Diet for Prevention of Coronary Heart Disease Diet
More informationSaturated fat- how long can you go/how low should you go?
Saturated fat- how long can you go/how low should you go? Peter Clifton Baker IDI Heart and Diabetes Institute Page 1: Baker IDI Page 2: Baker IDI Page 3: Baker IDI FIGURE 1. Predicted changes ({Delta})
More informationDietary fats and cardiovascular disease
Dietary fats and cardiovascular disease An Evidence Check rapid review brokered by the Sax Institute for the National Heart Foundation. September 2017 An Evidence Check rapid review brokered by the Sax
More informationLow carbohydrate diets- do they have a place?
Low carbohydrate diets- do they have a place? Grant Schofield Professor of Public Health AUT University, Auckland NZ @grantsnz www.facebook.com/profgrant www.profgrant.com Atherogenic dyslipidemia is [primarily]
More informationModels of preventive care in clinical practice to achieve 25 by 25
Models of preventive care in clinical practice to achieve 25 by 25 Professor David A Wood Garfield Weston Professor of Cardiovascular Medicine International Centre for Circulatory Health Imperial College
More information10/8/2015. MN Nursing Conference October 7th, 2015 Michael Miedema, MD MPH. None
MN Nursing Conference October 7th, 2015 Michael Miedema, MD MPH None 1 Objectives Why the need for change in the guidelines? What is the potential impact of these guidelines? Where do we go from here?
More informationFinnish international trade 2017 Figures and diagrams. Finnish Customs Statistics
Finnish international trade 217 Figures and diagrams Finnish Customs Statistics IMPORTS, EXPORTS AND TRADE BALANCE 199-217 Billion e 7 6 5 4 3 2 1-1 9 91 92 93 94 95 96 97 98 99 1 2 3 4 5 6 7 8 9 1 11
More information508 the number of suicide deaths in deaths per 100,000 people was the suicide rate in Suicide deaths in 2013 by gender
An overview of suicide statistics This document summarises information about suicide deaths in New Zealand covering up to 13. It does not attempt to explain causes of suicidal behaviour or causes of changes
More informationFinnish international trade 2017 Figures and diagrams. Finnish Customs Statistics
Finnish international trade 217 Figures and diagrams Finnish Customs Statistics IMPORTS, EXPORTS AND TRADE BALANCE 199-217 Billion e 7 6 5 4 3 2 1-1 9 91 92 93 94 95 96 97 98 99 1 2 3 4 5 6 7 8 9 1 11
More informationEating Patterns. did you know. Peanuts and Peanut Butter 67% Peanut butter is one of the most frequently consumed plant proteins in the U.S.
Peanuts are the Most Popular Nut Peanuts are the most commonly eaten nuts in America. When peanut butter is factored in, they comprise over 2/3 of the nut consumption in the U.S. Pecans 4% 2% Pistachios
More informationReplacement Of Partially Hydrogenated Soybean Oil By Palm Oil In Margarine Without Unfavorable Effects On Serum Lipoproteins
Replacement Of Partially Hydrogenated Soybean Oil By Palm Oil In Margarine Without Unfavorable Effects On Serum Lipoproteins Muller H, Jordal O, et al. (998) Replacement of partially hydrogenated soybean
More informationMetabolic Health: The impact of Dairy Matrix. Arne Astrup, MD, DMSc Head of department & professor. Department of Nutrition, Exercise and Sports
Department of Nutrition, Exercise and Sports Metabolic Health: The impact of Dairy Matrix 3 October 2017 Dias 1 Arne Astrup, MD, DMSc Head of department & professor Department of Nutrition, Exercise and
More informationMetabolic Health: The impact of Dairy Matrix. Arne Astrup, MD, DMSc Head of department & professor. Department of Nutrition, Exercise and Sports
Metabolic Health: The impact of Dairy Matrix 1 November 2017 Dias 1 Arne Astrup, MD, DMSc Head of department & professor EFSA: As low as possible 1 November 2017 Dias 2 People don t want to hear the truth
More informationSecondary prevention and systems approaches: Lessons from EUROASPIRE and EUROACTION
Secondary prevention and systems approaches: Lessons from EUROASPIRE and EUROACTION Dr Kornelia Kotseva National Heart & Lung Insitute Imperial College London, UK on behalf of all investigators participating
More informationPublic Health Nutrition:
Capital Region of Denmark Research Centre for Prevention and Health Public Health Nutrition: Major Areas in Need of Decisions Update on trans and saturated fats What might taxes and regulations have to
More informationThe Rockefeller Report I. The Rockefeller Report II. The Rockefeller Study. The Mediterranean Diet MEDITERRANEAN DIET. Antonia Trichopoulou, MD.
MEDITERRANEAN DIET The Rockefeller Report I Antonia Trichopoulou, MD. WHO Collaborating Centre for Nutrition Medical School, University of Athens Summer School in Public Health Nutrition and Ageing The
More informationNutritional Benefits of Animal Products
Nutritional Benefits of Animal Products Ruth K Price 1, Alison J Yeates 1, L Kirsty Pourshahidi 1, M Barbara E Livingstone 1 1 Northern Ireland Centre for Food and Health (NICHE), Ulster University, Cromore
More informationFOURIER STUDY GREYLOCK PRESS: CTS PRODUCT SAMPLE - FOURIER YES. Did the study achieve its main objective?
FOURIER STUDY Did the study achieve its main objective? 2 15% 1 5% 9.8% YES FOURIER compared Repatha with placebo in patients who were taking a statin and had hardening or narrowing of the arteries and
More informationNutrition and Health Benefits of Rice Bran Oil. Dr. B. Sesikeran, MD, FAMS Former Director National Institute of Nutrition (ICMR) Hyderabad
Nutrition and Health Benefits of Rice Bran Oil Dr. B. Sesikeran, MD, FAMS Former Director National Institute of Nutrition (ICMR) Hyderabad 1 Fats are needed for life Energy 9 K Cals/g Low fat intakes in
More informationCardiovascular health benefits of plant-based eating
Cardiovascular health benefits of plant-based eating Ian Rowland University of Reading Alpro Foundation Student Symposium March 2017 Leeds Overview What is plant-based eating? Cardiovascular disease Benefits
More informationSTABILITY Stabilization of Atherosclerotic plaque By Initiation of darapladib TherapY. Harvey D White on behalf of The STABILITY Investigators
STABILITY Stabilization of Atherosclerotic plaque By Initiation of darapladib TherapY Harvey D White on behalf of The STABILITY Investigators Lipoprotein- associated Phospholipase A 2 (Lp-PLA 2 ) activity:
More informationPerception and insights on fats and fatty acids: knowledge of fat quality of the diet
Perception and insights on fats and fatty acids: knowledge of fat quality of the diet Background Research indicates that consumers nowadays are very aware of their health and the major role nutrition plays
More informationNEWS & VIEWS. Hole in the diet-heart hypothesis?
NEWS & VIEWS Hole in the diet-heart hypothesis? Philip C. Calder Faculty of Medicine, University of Southampton, MP887 Southampton General Hospital, Tremona Road, Southampton SO16 6YD, United Kingdom and
More informationDietary Cholesterol in Cold Water Prawns: Implications for Cardiovascular Disease Risk
Dietary Cholesterol in Cold Water Prawns: Implications for Cardiovascular Disease Risk Professor Bruce Griffin Department of Nutritional Sciences Faculty of Health & Medical Sciences Coronary Heart Disease
More information3/25/2013. Healthy Aging: Approaches to Reduce Chronic Disease Risk. Overview. Chronic disease risk and older adults
Healthy Aging: Approaches to Reduce Chronic Disease Risk Alice H. Lichtenstein, D.Sc. Gershoff Professor of Nutrition Science and Policy Tufts University Overview Chronic disease risk and older adults
More informationSteering committee members:
Steering committee members: Prof. R. Uauy (Chair, President of International Union for Nutrition Scienc Prof. P. Puska (Co-chair, President elect of the World Heart Foundation) Prof. I. Elmadfa (President
More informationEPOA. Latest Insights on Palm Oil & Health. European Industry Meeting on Palm Oil Nicolette Drieduite I EPOA Project team member I Cargill 2 June 2015
EPOA Latest Insights on Palm Oil & Health European Industry Meeting on Palm Oil Nicolette Drieduite I EPOA Project team member I Cargill 2 June 2015 Summary 1. In the nineties palm oil s success was related
More informationDietary Fats and Oils March 2015
Dietary Fats and Oils March 2015 TABLE OF CONTENTS EXECUTIVE SUMMARY 2 DEFINITIONS AND CLASSIFICATIONS 5 DIETARY FATS & OILS 7 Total fat 8 Saturated fatty acids 8 Monounsaturated fatty acids (MUFA) 11
More informationSeafood consumption, the DHA content of mothers' milk and prevalence rates of postpartum depression: a cross-national, ecological analysis
Seafood consumption, the DHA content of mothers' milk and prevalence rates of postpartum depression: a cross-national, ecological analysis 1 Journal of Affective Disorders: Volume 69, Issues 1-3, May 2002,
More informationQUANTITY VERSUS QUALITY OF FAT IN THE DIET. Marius Smuts
QUANTITY VERSUS QUALITY OF FAT IN THE DIET Marius Smuts Centre of Excellence in Nutrition marius.smuts@nwu.ac.za CONTENT Background on fatty acids Roles of Essential fats Quantity of fat in the diet Quality
More informationJohn J.P. Kastelein MD PhD Professor of Medicine Dept. of Vascular Medicine Academic Medial Center / University of Amsterdam
Latest Insights from the JUPITER Study John J.P. Kastelein MD PhD Professor of Medicine Dept. of Vascular Medicine Academic Medial Center / University of Amsterdam Inflammation, hscrp, and Vascular Prevention
More informationEffects of Dietary Fat Intake on HDL Metabolism
Elmer ress Review J Clin Med Res. 2015;7(3):145-149 Effects of Dietary Fat Intake on HDL Metabolism Hidekatsu Yanai a, c, Hisayuki Katsuyama a, Hidetaka Hamasaki a, Shinichi Abe b, Norio Tada b, Akahito
More informationFLAXSEED Health Benefits and Functionality. Kelley C. Fitzpatrick Director of Health FLAX COUNCIL OF CANADA
FLAXSEED Health Benefits and Functionality Kelley C. Fitzpatrick Director of Health FLAX COUNCIL OF CANADA Consumers are interested in Positive Nutrition The trend is no longer just to remove bad ingredients
More informationThe Role of Monounsaturated Fatty Acids in Cardiovascular Disease. and Diabetes Mellitus Type 2. By Jovan Duvall. May 21 st 2012 NUTR 420
Duvall 1 The Role of Monounsaturated Fatty Acids in Cardiovascular Disease and Diabetes Mellitus Type 2 By Jovan Duvall May 21 st 2012 NUTR 420 Duvall 2 Introduction American s waistbands are not the only
More informationA Fresh Perspective. Lean Beef and Heart Health: ... Fresh red meat is not associated with CHD risk
Spring 2012... Fresh red meat is not associated with CHD risk R Lean Beef and Heart Health: A Fresh Perspective esearchers from the Harvard School of Public Health recently concluded that consuming 100
More informationDr. Laurence Eyres ECG Ltd Associate Professor Marie Wong, Massey University Oils and Fats Specialist Group November 2013
New Zealand Extra Virgin Olive Oil and Your Health The Facts Dr. Laurence Eyres ECG Ltd Associate Professor Marie Wong, Massey University Oils and Fats Specialist Group November 2013 Estimated influence
More informationProf. Renata Cífková, MD, CSc.
Prof. Renata Cífková, MD, CSc. Head of the Department of Preventive Cardiology, Thomayer Teaching Hospital, Prague Focuses on arterial hypertension epidemiology, clinical trials, target organ damage prevention
More informationFAT. Dr. Shamsul Azahari Zainal Badari Department of Resource Management and Consumer Studies Faculty of Human Ecology
FAT Dr. Shamsul Azahari Zainal Badari Department of Resource Management and Consumer Studies Faculty of Human Ecology OBJECTIVES LECTURE By the end of this lecture, student can: Define what is lipid/fat
More informationDairy, Saturated Fat and Cardiometabolic Disease
Dairy, Saturated Fat and Cardiometabolic Disease Anne Mullen, BSc, PhD, FHEA, RD Director of Nutrition at The Dairy Council February 2016 Email: a.mullen@dairycouncil.org.uk Tel: 020 7025 0560 Web: www.milk.co.uk
More informationEIIW Competitiveness Report on the EU Market
EIIW Competitiveness Report on the EU Market Jens K. Perret Wuppertal, January 215 Preliminary European Institute for International Economic Relations at the University of Wuppertal, Rainer-Gruenter-Str.
More informationA healthy approach to dietary fats: understanding the science and taking action to reduce consumer confusion
A healthy approach to dietary fats: understanding the science and taking action to reduce consumer confusion The Harvard community has made this article openly available. Please share how this access benefits
More informationMaintain Cholesterol
Maintain Cholesterol What is Cholesterol? Cholesterol is a Lipid Molecule that has a waxy appearance and is found in every cell of the body and has some important natural functions. It is manufactured
More informationComposition and Structure of Oil and Fats and its Relationship to Health and Nutrition
Composition and Structure of Oil and Fats and its Relationship to Health and Nutrition SB Neoh* & K. Sundram** * Managing Director, Soon Soon Oilmills Sdn Bhd, Malaysia **Deputy CEO and Director, Science
More informationFacts on fats: Dietary fats and health
Facts on fats: Dietary fats and health 13 February 2015 This part of our Facts on Fats review explains in more detail the different functions that dietary fats have in the human body, it covers dietary
More informationOf Cows and Men: Reviewing the Link Between Dairy Fat and Human Health
Of Cows and Men: Reviewing the Link Between Dairy Fat and Human Health The Times, They Are A Changing To keep in mind: what 100% of experts believe and recommend usually changes over time Thomas Kuhn Eduardo
More informationThe Great Dairy Debate. Is dairy healthy for you or not? It isn t black and white
The Great Dairy Debate Is dairy healthy for you or not? It isn t black and white Dairy (sticky note affinity analysis) Benefits Concerns Learning Objectives Identify nutrients found in different dairy
More informationHealth Maintained and Restored Begins With Nutrition
Health Maintained and Restored Begins With Nutrition T. Colin Campbell Professor Emeritus Nutritional Biochemistry Cornell University 1 1 To The Future From The Present Hi Carb:Lo Fat:Lo Prot Lo Carb:Hi
More informationLipids. PBHL 211 Darine Hachem, MS, LD
Lipids PBHL 211 Darine Hachem, MS, LD Outline Functions of lipids in our body Types of lipids Sources of lipids Recommendation of fat intake Fat association with heart diseases Provide energy (9Kcal/g
More informationWhat is a healthy balance of fats and oils?
What is a healthy balance of fats and oils? AUGUST 2017 for Healthcare Professionals EXPERT SCIENTIFIC ROUNDTABLE This roundtable report was created by a multidisciplinary panel of leading academics and
More informationNo conflicts of interest or disclosures
Egg and Dairy Consumption: Impact on CVD Risk No conflicts of interest or disclosures Vasanti Malik, ScD Research Scientist Department of Nutrition Harvard School of Public Health Cardiovascular Disease
More informationCurrent dietary habits in Europe far from plant based eating
Current dietary habits in Europe far from plant based eating Stefaan De Henauw Ghent University Department of Public Health Stefaan.dehenauw@ugent.be The menu What is plant based diet? Nutrition transition
More informationDietary Fats & Health
Dietary Fats & Health Navigating the Slippery Slope Ed Cox, M.D. Fat is good for you Repeat after me: Fat in my diet is good for me The myth USDA, American Heart Assn, American Cancer Society have kept
More informationOverview of European Consumption Databases
FEDERAL INSTITUTE FOR RISK ASSESSMENT Overview of European Consumption Databases Katrin Büsch Workshop Food Consumption Data and Dietary Exposure in the European Union, 15-16 May 2008, Berlin Introduction
More informationREVIEW ABSTRACT. 674 ã2015 American Society for Nutrition. Adv Nutr 2015;6:674 93; doi: /an
REVIEW A Systematic Review of High-Oleic Vegetable Oil Substitutions for Other Fats and Oils on Cardiovascular Disease Risk Factors: Implications for Novel High-Oleic Soybean Oils 1,2 Peter J Huth, 3 *
More informationSaudi Arabia February Pr Michel KOMAJDA. Université Pierre et Marie Curie Hospital Pitié Salpétrière
Prevention of Cardiovascular events with Ivabradine: The SHIFT Study Saudi Arabia February 2011 Pr Michel KOMAJDA Université Pierre et Marie Curie Hospital Pitié Salpétrière Paris FRANCE Declaration Of
More informationPalliative nursing care of children and young people across Europe
Palliative nursing care of children and young people across Europe Results of a postal survey in August 2016 Updated in April 2017 (presented at the 29th PNAE-meeting in Naples/Italy on 28th April 2017)
More informationANSC/NUTR) 618 LIPIDS & LIPID METABOLISM Dietary fat and Cardiovascular Disease
ANSC/NUTR) 618 LIPIDS & LIPID METABOLISM Dietary fat and Cardiovascular Disease I. Investigations in humans relating dietary fat intake to serum cholesterol A. Ansel Keys: the Keys Formula Cholesterol
More informationFuture directions for nutritional and therapeutic research in omega-3 3 lipids
Future directions for nutritional and therapeutic research in omega-3 3 lipids Philip Calder Professor of Nutritional Immunology University of Southampton Aim To review dietary sources and intakes of long
More informationTHE IMPORTANCE OF ANIMAL-SOURCE FOODS IN WESTERN DIETS
INSTITUTE FOR FOOD, NUTRITION AND HEALTH THE IMPORTANCE OF ANIMAL-SOURCE FOODS IN WESTERN DIETS Ian Givens Professor of Food Chain Nutrition University of Reading 1 Copyright University of Reading LIMITLESS
More informationPerformance against the USLP global nutrition targets in key countries 2017
Performance against the USLP global nutrition targets in key countries Please refer to the Sustainable Living section of www.unilever.com for a full description of global progress HIGHEST NUTRITIONAL STANDARDS
More informationSaturated Fat and Cardiometabolic Risk Factors, Coronary Heart Disease, Stroke, and Diabetes: A Fresh Look at the Evidence
Saturated Fat and Cardiometabolic Risk Factors, Coronary Heart Disease, Stroke, and Diabetes: A Fresh Look at the Evidence The Harvard community has made this article openly available. Please share how
More informationNutrition and Cancer: What We Know, What We Don t Know Walter C. Willett, MD, DrPH
Nutrition and Cancer: What We Know, What We Don t Know Walter C. Willett, MD, DrPH Department of Nutrition Harvard T. H. Chan School of Public Health November 16, 2016 Breast Cancer Deaths / 100,000 pop
More informationINC International Nut & Dried Fruit Council Symposium Nuts in Health and Disease. Granada, 19 th September 2013 Press Kit
INC International Nut & Dried Fruit Council Symposium Nuts in Health and Disease Granada, 19 th September 2013 Press Kit Index Introduction Keynote Speakers Conference Abstract Useful Information The International
More informationTHE SAME EFFECT WAS NOT FOUND WITH SPIRITS 3-5 DRINKS OF SPIRITS PER DAY WAS ASSOCIATED WITH INCREASED MORTALITY
ALCOHOL NEGATIVE CORRELATION BETWEEN 1-2 DRINKS PER DAY AND THE INCIDENCE OF CARDIOVASCULAR DISEASE SOME HAVE SHOWN THAT EVEN 3-4 DRINKS PER DAY CAN BE BENEFICIAL - WHILE OTHERS HAVE FOUND IT TO BE HARMFUL
More informationT h e g l o b a l d i s t r i b u t i o n of r o u t i n e a n d n o n - r o u t i n e w o r k. F i n d i n g s f r o m P I A A C, S T E P & C U L S
T h e g l o b a l d i s t r i b u t i o n of r o u t i n e a n d n o n - r o u t i n e w o r k. F i n d i n g s f r o m P I A A C, S T E P & C U L S P i o t r L e w a n d o w s k i ( I B S, I Z A ) W o
More informationWELLNESS COACHING. Wellness & Personal Fitness Solution Providers
WELLNESS COACHING Wellness & Personal Fitness Solution Providers Introducing Ourselves... We are Personal Wellness Coaches 2 We help people look and feel better by: - Educating on proper nutrition (80%)
More informationFlavonoids and Cardiovascular Disease
Flavonoids and Cardiovascular Disease Julie Lovegrove Hugh Sinclair Professor of Human Nutrition University of Reading Micronutrients and Health APPG University of Reading 2014 www.reading.ac.uk Global
More informationDesign and Analysis of a Cancer Prevention Trial: Plans and Results. Matthew Somerville 09 November 2009
Design and Analysis of a Cancer Prevention Trial: Plans and Results Matthew Somerville 09 November 2009 Overview Objective: Review the planned analyses for a large prostate cancer prevention study and
More informationDECLARATION OF CONFLICT OF INTEREST. None
DECLARATION OF CONFLICT OF INTEREST None Dietary changes and its influence on cardiovascular diseases in Asian and European countries Problems of Eastern European countries for cardiovascular disease prevention
More informationOmega-3 Fatty Acids. Alison L. Bailey MD, FACC Erlanger Heart and Lung Institute/University of Tennessee COM
Omega-3 Fatty Acids Alison L. Bailey MD, FACC Erlanger Heart and Lung Institute/University of Tennessee COM Chattanooga @a_l_bailey Disclosures None Objectives Describe omega-3 fatty acids Review the historic
More informationSetting the Record Straight on Cholesterol, Saturated Fat, and Heart Disease Risk
NUTRI-BITES Webinar Series Setting the Record Straight on Cholesterol, Saturated Fat, and Heart Disease Risk will begin at the top of the hour Audio for today s presentation is being broadcast over your
More informationDietary Fat and Risk of Cardiovascular Disease: Recent Controversies and Advances
Annu. Rev. Nutr. 2017. 37:423 46 First published as a Review in Advance on June 23, 2017 The Annual Review of Nutrition is online at nutr.annualreviews.org https://doi.org/10.1146/annurev-nutr-071816-064614
More information